Search clinical trials for: efficacy and safety

Total 473948 results

Cochlear
NAMSA; LWB Consulting

Not yet recruiting

Safety and Effectiveness of Cochlear Implantation in an Expanded Adult Population (ACE)

Hearing Loss, Sensorineural | Hearing Loss, Bilateral

United States
WELT corp

Recruiting

Study of Efficacy and Safety of WELT-ED for Eating Disorder (WCTP-ED-B-01)

Binge-Eating Disorder | Binge Eating | Eating Disorders

Korea, Republic of
Zhongmou Therapeutics

Not yet recruiting

Safety and Efficacy Study of Novel Gene Therapy ZM-02 for Retinitis Pigmentosa Patients (ZM-02)

Retinitis Pigmentosa

China
Suzhou Municipal Hospital

Not yet recruiting

Safety and Efficacy Study of NGGT006 in Refractory Hypercholesterolemia Patients

Familial Hypercholesterolemia | Refractory Hypercholesterolemia
University of Monastir

Not yet recruiting

Efficacy and Safety of Intravenous Diazepam Given at 2 Different Doses Compared to Placebo in Acute Peripheral Vertigo (Vertigo)

Vertigo, Peripheral
PharmaEssentia

Not yet recruiting

Efficacy and Safety of Ropeginterferon Alfa 2b (P1101) for Patients With Low-Risk Polycythemia Vera (PV)

Polycythemia Vera | Myeloproliferative Neoplasm
CorrectSequence Therapeutics Co., Ltd

Recruiting

A Safety and Efficacy Study Evaluating CS-101 in Subjects With β-Thalassemia Major

Beta-Thalassemia Major

China
University Hospital, Rouen

Not yet recruiting

Efficacy and Safety of Immunosuppression, Caplacizumab and Plasma Infusion Without Therapeutic Plasma Exchange in Immune-mediated Thrombotic Thrombocytopenic Purpura: Multicentric Non-inferiority Single-arm Study (PEX-FREE)

Thrombotic Microangiopathies
Wuhan Union Hospital, China
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine; The Second... and other collaborators

Recruiting

Clinical Trial of the Safety and Efficacy of Peripheral Nerve Stimulation in the Treatment of Postherpetic Neuralgia.

Neuropathic Pain | Postherpetic Neuralgia

China
University Hospital Tuebingen

Not yet recruiting

First-in-man Single-dose and Multiple Dose Study to Evaluate the Safety, Tolerability and Efficacy ofHY-133 (HY-133)

Staphylococcus Aureus
Addpharma Inc.

Not yet recruiting

A Study to Evaluate the Efficacy and Safety of AD-224

Hypertension,Essential
Sanofi

Recruiting

A Study to Test the Efficacy and Safety of Riliprubart Against the Usual Treatment of Intravenous Immunoglobulin (IVIg) in People With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) (VITALIZE)

Chronic Inflammatory Demyelinating Polyneuropathy

United States
Dong-A ST Co., Ltd.

Not yet recruiting

Efficacy and Safety of DA5221-T When Added to Ongoing DA5221-B1 and DA5221-B2 Combination Therapy in Patients With Type 2 Diabetes Who Have Inadequate Glycemic Control

Type 2 Diabetes

Korea, Republic of
King Chulalongkorn Memorial Hospital

Not yet recruiting

Efficacy and Safety of Retrograde Intraarticular Injection Via Drain Tube, Topical Soaking of Tranexamic Acid (TXA), or Placebo in Elderly Patients With Femoral Neck Fractures Undergoing Cementless Bipolar Hemiarthroplasty - a Randomized Controlled Trial (TXA)

Femoral Neck Fracture | Bipolar Hemiarthroplasty

Thailand
AJU Pharm Co., Ltd.
GL Pharm Tech Corporation

Recruiting

Efficacy and Safety of AJU-S56 5% in Dry Eye Syndrome Patients

Dry Eye Syndromes

Korea, Republic of
Hutchmed

Recruiting

The Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of HMPL-523 in Adult Subjects With Immune Thrombocytopenia (ITP)

Pathologic Processes | Immune System Diseases | Autoimmune Diseases | Hematologic Diseases | Hemorrhage | Hemorrhagic Disorders | Thrombotic Microangiopathies | Purpura | Purpura, Thrombocytopenic | Skin Manifestations | Thrombocytopenia | Purpura, Thrombocytopenic, Idiopathic | Immune Thrombocytopenia | Blood Coagulation... and other conditions

United States, Spain, Norway, Australia, Germany
JKT Biopharma Co., Ltd.

Not yet recruiting

SHEN211 Tablets for the Treatment of Mild and Moderate Novel Corona Virus Infections (COVID-19)

COVID-19

China
InnoVec Biotherapeutics Inc.
Peking Union Medical College Hospital

Recruiting

Safety and Efficacy Study of IVB102 Injection in Subjects With X-linked Retinoschisis

Eye Diseases | Retinal Degeneration | Retinal Disease | Retinoschisis

China
Staidson (Beijing) Biopharmaceuticals Co., Ltd

Recruiting

Safety and Efficacy of STSP-0601 in Adult Patients With Hemophilia A or B With Inhibitor

Hemophilia

China
Regional Cardiology Center, The Copper Health Centre...

Recruiting

Lower Silesia Sinus Reducer Registry (LSSRR)

Safety Issues | Efficacy, Self

Poland
Tianjin Medical University General Hospital

Recruiting

Efficacy and Safety of Liposomal Bupivacaine Under ERAS Concept for Postoperative Analgesia of Ultrasound-Guided QLB in Gynecologic Laparoscopic Patients: A Randomized, Single-blind, Active-Controlled Clinical Study

Pharmacological Action

China
The Second Affiliated Hospital of Kunming Medical...
Guizhou Provincial People's Hospital; Central South University; First Affiliated... and other collaborators

Not yet recruiting

Safety and Efficacy of Venetoclax Combination With Decitabine(DEC3-VEN) in the Treatment of AML in the Adult

Acute Myeloid Leukemia, Adult

China
Gerbera Therapeutics, Inc.

Not yet recruiting

A Study to Assess the Efficacy, Safety, and Tolerability of Oral NORA520 in Adults With Severe Postpartum Depression (NuMom)

Postpartum Depression | Depression, Postpartum | Postnatal Depression | Post-partum Depression | Post-Natal Depression

United States
The First Affiliated Hospital of Guangzhou Medical...

Recruiting

Efficacy and Safety of Single-port Surgical Robot System in Thoraic Surgery

Lung Cancer

China
Kyowa Kirin China Pharmaceutical Co., Ltd.

Recruiting

A Study to Evaluate the Efficacy and Safety of KW-0761 in Chinese Subjects With Mycosis Fungoides or Sézary Syndrome Previously Treated With Systemic Therapy

Cutaneous T-Cell Lymphoma

China
Bioray Laboratories
Institute of Hematology & Hospital of Blood Diseases, Chinese Academy of...

Not yet recruiting

Clinical Study on the Safety and Efficacy of BRL-101 in the Treatment of Sickle Cell Disease

Sickle Cell Disease
Lin Chen

Recruiting

Tirelizumab Combined With Chemotherapy in the Treatment of HER-2 Negative Locally Advanced Gastric Cancer

Efficacy | Safety | HER2 Negative | Locally Advanced Gastric Carcinoma

China
Il-Yang Pharm. Co., Ltd.

Not yet recruiting

Study to Evaluate the Efficacy and Safety of Ilaprazole 10 mg in Prevention NSAIDs Associated Peptic Ulcer

Peptic Ulcer

Korea, Republic of
Petrovsky National Research Centre of Surgery

Recruiting

Evaluation of the Efficacy and Safety of Surgical Device "Lymphoblock" for Prevention of Lymphorrhea in Patients With Thoracoabdominal Aorta Repair.

Aorta Abdominalis; Aneurysm | Aorta Thoracic; Aneurysm

Russian Federation
Merck Sharp & Dohme LLC

Recruiting

Efficacy and Safety of MK-1167 in Participants With Alzheimer's Disease Dementia Taking Stable Donepezil Treatment (MK-1167-007)

Alzheimer's Disease

United States
argenx

Not yet recruiting

A Study to Evaluate Safety and Efficacy of Empasiprubart in Adults With Dermatomyositis (empacific)

Myositis | Dermatomyositis
The First Affiliated Hospital with Nanjing Medical...

Recruiting

Efficacy and Safety of TMZ Plus 6-MP in the Patients With Recurrent Glioblastoma

Cancer | Glioblastoma | Temozolomide

China
University of Arizona
United States Department of Defense

Not yet recruiting

Safety and Efficacy of Angiotensin (1-7) in Persons With Moderate to Severe Traumatic Brain Injury (ANGel T)

Traumatic Brain Injury
EXO Biologics S.A.

Recruiting

Safety and Efficacy of MSC-EVs in the Prevention of BPD in Extremely Preterm Infants (EVENEW)

Bronchopulmonary Dysplasia

Italy, Belgium
The Fourth Affiliated Hospital of Zhejiang University...

Recruiting

Efficacy and Safety of Chemotherapy With XELOX (Oxaliplatin + Capecitabine) and Bevacizumab in Combination With Adebrelimab in First-line Treatment of Microsatellite Stable (MSS) Initially Unresectable Metastatic Colorectal Cancer

Colorectal Cancer Metastatic

China
Tianjin Medical University Cancer Institute and...
CSPC Ouyi Pharmaceutical Co., Ltd.

Recruiting

Efficacy and Safety of Irinotecan Liposome Injection Combined With 5-FU/LV± Immunotherapy in First-line Gemsitabine + Immunoprogressive Patients With Metastatic Biliary Tract Cancer

Metastatic Biliary Tract Cancer

China
Materia Medica Holding

Recruiting

Clinical Trial of the Efficacy and Safety of Raphamin in Prevention of Recurrences of Chronic Bacterial Cystitis

Cystitis Chronic | Cystitis Bacterial | Recurrence of Chronic Bacterial Cystitis

Russian Federation
Innovaderm Research Inc.

Not yet recruiting

Efficacy, Safety, and Tolerability of Abrocitinib in Subjects With Moderate to Severe Chronic Hand Eczema Refractory to Corticosteroid Therapy

Chronic Hand Eczema

Canada
Regional Cardiology Center, The Copper Health Centre...
Department of Cardiology, Provincial Specialized Hospital in Legnica, 59-200...

Recruiting

Lower Silesia Culotte Bifurcation Registry (LSCBR). (LSCBR)

Safety Issues | Efficacy, Self

Poland
Bio-Thera Solutions

Not yet recruiting

A Study to Evaluate PK, Efficacy, and Safety of BAT3306 Plus Chemo and Compare With Keytruda®(EU/US) in Participants With IV nqNSCLC

Carcinoma, Non-Small-Cell Lung
Encoded Therapeutics

Recruiting

A Clinical Study to Evaluate the Safety and Efficacy of ETX101, an AAV9-Delivered Gene Therapy in Children With SCN1A-positive Dravet Syndrome (UK Only)

Dravet Syndrome

United Kingdom
Sanofi
Regeneron Pharmaceuticals

Recruiting

A Proof-of-Concept Study to Assess the Efficacy, Safety and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Non-cystic Fibrosis Bronchiectasis

Bronchiectasis

United Kingdom, Israel, Japan, United States, Canada, Chile
The First Affiliated Hospital of Xinxiang Medical...

Recruiting

the Efficacy and Safety of Ondansetron Oral Soluble Pellicles

Nausea and Vomiting

China
Yuhan Corporation

Recruiting

Study to Evaluate the Efficacy and Safety of TEL/AML/CTD in Elderly Patients With Essential Hypertension

Essential Hypertension

Korea, Republic of
Avistone Biotechnology Co., Ltd.

Not yet recruiting

Efficacy and Safety Evaluation of PLB1004 in Patients With Non-squamous NSCLC Harboring EGFR Exon 20 Insertion.

Non-Small-Cell Lung Cancer
Jazz Pharmaceuticals

Recruiting

Efficacy and Safety of Zanidatamab With Standard-of-care Therapy Against Standard-of-care Therapy for Advanced HER2-positive Biliary Tract Cancer

Biliary Tract Cancer | HER2 Gene Mutation

United States, Puerto Rico
Waterstone Pharmaceutical (Wuhan) Co., LTD.

Recruiting

A Study to Evaluate the Safety and Efficacy of WS016 in Patients With Hyperkalemia.

Hyperkalemia

China
Anhui Provincial Hospital
Leman Biotech Co., Ltd

Recruiting

Safety and Efficacy of Metabolically Armed CD19 CAR-T Cells (Meta10-19) in the Treatment of Relapsed and/or Refractory CD19-positive B Cell Hematological Malignancies Clinical Research

Acute Lymphoblastic Leukemia | Non-hodgkin Lymphoma

China
Fujian Medical University

Recruiting

A Study on the Safety and Efficacy of the Combination of Candenizumab, Lenvatinib, and SOX Regimen in the Treatment of HER2 Negative Advanced Gastric or Gastroesophageal Junction Adenocarcinoma Patients

Overall Response Rate

China
InventisBio Co., Ltd

Recruiting

Evaluate the Efficacy and Safety of D-2570 in Participants With Moderate-to-Severe Plaque Psoriasis

Plaque Psoriasis

China

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