Search clinical trials for: epidermal transcriptome

Total 901 results

University of Alabama at Birmingham
Ultragenyx Pharmaceutical Inc

Completed

A Trial to Assess the Safety and Efficacy of KRN23 in Epidermal Nevus Syndrome (ENS) (ENS)

Epidermal Nevus Syndrome

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI); Merck Sharp & Dohme LLC

Completed

Cetuximab and Pembrolizumab in Treating Patients With Colorectal Cancer That is Metastatic or Cannot Be Removed by Surgery

Recurrent Colorectal Carcinoma | Stage IVA Colorectal Cancer | Stage IVB Colorectal Cancer

United States
Millennium Pharmaceuticals, Inc.

Approved for marketing

An Expanded Access Protocol for Mobocertinib in Refractory Non-small Cell Lung Cancer (NSCLC) Participants With Epidermal Growth Factor Receptor (EGFR) Exon20 Insertion Mutations

Carcinoma, Non-Small-Cell Lung
National Institute of Arthritis and Musculoskeletal...

Completed

National Registry for Ichthyosis and Related Disorders

Ichthyosis | Ichthyosis, X-Linked | Ichthyosis, Lamellar | Darier Disease | Hailey-Hailey Disease | Hyperkeratosis, Epidermolytic | Keratoderma

United States
Assistance Publique - Hôpitaux de Paris
Institut National de la Santé Et de la Recherche Médicale, France; National... and other collaborators

Completed

Transcriptome Assessment After Cardiac Arrest (OMECARD)

Out-Of-Hospital Cardiac Arrest After Initial Successful Resuscitation

France
Academisch Ziekenhuis Maastricht
The Netherlands Cancer Institute; ZonMw: The Netherlands Organisation for Health...

Completed

Pharmacokinetic Boosting of Osimertinib (OSIBOOST)

Non Small Cell Lung Cancer

Netherlands
Pega-One S.A.S.
ICON plc

Withdrawn

Imgatuzumab in Patients With Advanced Cutaneous Squamous Cell Carcinoma (I-PACE)

Cutaneous Squamous Cell Carcinoma
National Cancer Institute (NCI)

Completed

Ad/HER2/Neu Dendritic Cell Cancer Vaccine Testing

Breast Cancer | Breast Neoplasms | Adenocarcinomas | Metastatic Solid Tumors Characterized by HER2/Neu Expression

United States
Kyowa Kirin Co., Ltd.

Completed

A Study of KRN23 in Subjects With Tumor-Induced Osteomalacia or Epidermal Nevus Syndrome

Tumor-Induced Osteomalacia or Epidermal Nevus Syndrome

Japan, Korea, Republic of
Dana-Farber Cancer Institute
Pfizer

Completed

Palbociclib With Everolimus + Exemestane In BC

Human Epidermal Growth Factor 2 Negative Carcinoma of Breast | Hormone Receptor (HR)-Positive Breast Cancer

United States
National Taiwan University Hospital

Completed

Optimal EGFR TKIs Treatment Strategies for Lung Adenocarcinoma Harboring EGFR Exon 19 Deletion Variants

Tumor Progression | EGFR Exon 19 Mutation

Taiwan
Centre Hospitalier Universitaire Vaudois

Completed

Nutritional and Metabolic Management of Toxidermia Patients Requiring Intensive Care (TEN Metabolism) (TEN metabolism)

Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum
Shanghai 10th People's Hospital

Completed

GLP-1 RAs in Patients With Polycystic Ovary Syndrome (PCOS)

Polycystic Ovary Syndrome

China
Celcuity, Inc.

Completed

A Study To Assess The Tolerability And Clinical Activity Of Gedatolisib In Combination With Palbociclib/Letrozole Or Palbociclib/Fulvestrant In Women With Metastatic Breast Cancer

Breast Cancer

United States
Checkpoint Therapeutics, Inc.

Completed

Phase I/II Study of CK-101 in NSCLC Patients and Other Advanced Solid Tumors

Lung Diseases | Adenocarcinoma | Carcinoma, Non-Small-Cell Lung | Lung Neoplasms

United States, Thailand, New Zealand, Australia, Poland
PT. Daewoong Infion
Equilab International

Completed

Efficacy and Safety Evaluation of EASYEF® in Acute Wound (Split-thickness Skin Graft Donor Site)

Skin Graft Scar | Split-Thickness Skin Graft (STSG)

Indonesia
National Institute of Arthritis and Musculoskeletal...

Terminated

Topical Ruxolitinib for Cutaneous Chronic Graft Versus Host Disease (cGVHD)

Graft Versus Host Disease | JNS Kinase | Topical Administration

United States
Hoffmann-La Roche

Terminated

A Phase II Study Comparing The Efficacy Of Venetoclax + Fulvestrant Vs. Fulvestrant In Women With Estrogen Receptor-Positive, Her2-Negative Locally Advanced Or Metastatic Breast Cancer Who Experienced Disease Recurrence Or Progression During Or After CDK4/6 Inhibitor Therapy (Veronica)

Estrogen Receptor-positive (ER+)/Human Epidermal Growth Factor Receptor (HER2)-Negative Locally Advanced or Metastatic Breast Cancer

Canada, United States, United Kingdom, Australia, Germany
PepsiCo Global R&D

Completed

NBA G-League Sweat Testing Study: Validity of the Gx Sweat Patch in Measuring Sweating Rate and Sweat Chloride Concentration During On-court Training With Basketball Players

Sweat Analysis

United States
Corporal Michael J. Crescenz VA Medical Center
University of Pennsylvania; National Institute on Aging (NIA)

Completed

Vasodilator Therapy for Heart Failure and Preserved Ejection Fraction

Heart Failure | Congestive Heart Failure

United States
Spanish Lung Cancer Group

Completed

Phase III Study (Tarceva®) vs Chemotherapy to Treat Advanced Non-Small Cell Lung Cancer in Patients With Mutations in the TK Domain of EGFR (EURTAC)

Non-Small Cell Lung Cancer

Spain, France, Italy
Spanish Lung Cancer Group

Completed

Individualized Treatment Based on Epidermal Growth Factor Receptor Mutations and Level of BRCA1 Expression in Advanced Adenocarcinoma (SLAT)

Non-small Cell Lung Cancer

Spain
Isfahan University of Medical Sciences

Completed

Intraorbital Dermoid/Epidermoid Cyst

Dermoid Cyst of Orbit
University Health Network, Toronto
Princess Margaret Hospital, Canada

Completed

Prospective Comprehensive Molecular Profiling In Neuroendocrine Tumors (NET-SEQ)

Neuroendocrine Tumors | Pancreatic Neuroendocrine Tumors

Canada
Hoffmann-La Roche

Completed

A Study of Trastuzumab Emtansine in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Breast Cancer Who Have Received Prior Anti-HER2 And Chemotherapy-based Treatment

Breast Cancer

Italy, Belgium, Canada, United Kingdom, Argentina, Australia, Austria, Brazil, Bulgaria, China, Croatia, Denmark, Dominican Republic, Ecuador, Estonia, Finland, France, Germany, Greece, Guatemala, Hong Kong, Hungary, Iceland, Indonesia, Irelan... and more
Montefiore Medical Center
Albert Einstein College of Medicine; Deciphera Pharmaceuticals LLC

Terminated

Rebastinib Plus Antitubulin Therapy With Paclitaxel or Eribulin in Metastatic Breast Cancer

Breast Cancer | Stage IV Breast Cancer | Recurrent Breast Carcinoma | Human Epidermal Growth Factor 2 Negative Carcinoma of Breast | Breast Adenocarcinoma

United States
Novartis Pharmaceuticals

Completed

A Study of PDR001 in Combination With CJM112, EGF816, Ilaris® (Canakinumab) or Mekinist® (Trametinib)

Colorectal Cancer, Triple Negative Breast Cancer, NSCLC - Adenocarcinoma

United States, France, Taiwan, Canada, Italy, Singapore, Belgium, Spain, Israel
Sun Pharmaceutical Industries Limited

Completed

A Study to Evaluate the Efficacy and Safety of Subcutaneous MK-3222, Followed by an Optional Long-Term Safety Extension Study, in Participants With Moderate-to-Severe Chronic Plaque Psoriasis (MK-3222-010) (reSURFACE 1)

Plaque Psoriasis
Pfizer

Completed

PF-06804103 Dose Escalation in HER2 Positive and Negative (Negative Only in Part 2) Solid Tumors

Breast Neoplasms

Spain, Korea, Republic of, United States, Australia, Italy, Russian Federation
Daiichi Sankyo Co., Ltd.
AstraZeneca

Completed

DS-8201a in Human Epidermal Growth Factor Receptor 2 (HER2)-Expressing Gastric Cancer [DESTINY-Gastric01]

Neoplasm, Gastrointestinal

Korea, Republic of, Japan
Holostem Terapie Avanzate s.r.l.
Paracelsus Medical University

Terminated

Clinical Trial to Assess Safety and Efficacy of Autologous Cultured Epidermal Grafts Containing Epidermal Stem Cells Genetically Modified in Patients With JEB (HOLOGENE17) (HOLOGENE17)

Junctional Epidermolysis Bullosa

Austria
Laura Tosi
Children's National Research Institute; Ultragenyx Pharmaceutical Inc

Active, not recruiting

Burosumab for CSHS

Cutaneous Skeletal Hypophosphatemia Syndrome (CSHS) | Epidermal Nevus Syndrome

United States
MedSIR
Roche Pharma AG; Experior

Completed

T-DM1 and Non-pegylated Liposomal Doxorubicin in Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Metastatic Breast Cancer (THELMA)

Breast Cancer

France, Spain
M.D. Anderson Cancer Center

Completed

Four Quadrants Transverse Abdominus Plane (4Q-TAP) Block With Plain and Liposomal Bupivacaine vs. Thoracic Epidermal Analgesia (TEA) in Patients Undergoing Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy (CRS-HIPEC) on an Enhanced Recovery Pathway

Peritoneal Cancer

United States
Brigham and Women's Hospital
Patient-Centered Outcomes Research Institute; McGill University; VA Boston Healthcare...

Active, not recruiting

Comparative Effectiveness and Safety of Four Second Line Pharmacological Strategies in Type 2 Diabetes Study (CER-4-T2D)

Type2 Diabetes | Renal Disease | Cardiovascular Events

United States
Holostem Terapie Avanzate s.r.l.
Paracelsus Medical University

Terminated

Clinical Trial to Assess Safety and Efficacy of Autologous Cultured Epidermal Grafts Containing Epidermal Stem Cells Genetically Modified in Patients With RDEB. (HOLOGENE7)

Recessive Dystrophic Epidermolysis Bullosa

Austria
Weill Medical College of Cornell University

Withdrawn

Rifaximin Versus Lactulose in Renal Failure

Liver Cirrhosis | Renal Failure

United States
M.D. Anderson Cancer Center
GlaxoSmithKline; AstraZeneca

Completed

Topotecan and Gefitinib (Iressa) for Ovarian, Peritoneal, or Fallopian Tube Cancer

Peritoneal Neoplasms | Ovarian Cancer | Fallopian Tube Cancer

United States
Novartis Pharmaceuticals

Completed

Study of Capmatinib and Spartalizumab Combination Therapy vs Docetaxel in Non-small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung

United States, Belgium, Germany, France, Spain, Israel
Genentech, Inc.

Completed

Safety, Tolerability, and Pharmacokinetic (PK) Study of DHES0815A in Participants With Human Epidermal Growth Factor Receptor (HER)2-Positive Breast Cancer

Breast Cancer

United States, Korea, Republic of
Daiichi Sankyo, Inc.

Terminated

DS-1205c With Osimertinib for Metastatic or Unresectable Epidermal Growth Factor Receptor (EGFR)-Mutant Non-Small Cell Lung Cancer

Non-small Cell Lung Cancer (NSCLC)

Taiwan
Eli Lilly and Company
University of Colorado, Denver; Quintiles, Inc.; PPD; Parexel; Laboratory Corporation... and other collaborators

Completed

First-line Treatment of Patients With Stage IV Nonsquamous Non-Small Cell Lung Cancer With Necitumumab (IMC-11F8) and Pemetrexed-Cisplatin (INSPIRE)

Non Small Cell Lung Cancer

Belgium, Brazil, Russian Federation, United Kingdom, Australia, Germany, Hungary, Italy, Romania, United States, Austria, Canada, Croatia, France, Greece, Poland, Portugal, Slovakia, South Africa, Spain
Chul Kim
Bristol-Myers Squibb; AstraZeneca; Walter Reed National Military Medical Center; Hackensack Meridian Health

Active, not recruiting

Dasatinib and Osimertinib (AZD9291) in Advanced Non-Small Cell Lung Cancer With EGFR Mutations

Nonsmall Cell Lung Cancer | EGFR Gene Mutation

United States
Gilead Sciences

Completed

Switching to a Fixed Dose Combination of Bictegravir/Emtricitabine/Tenofovir Alafenamide (B/F/TAF) in Human Immunodeficiency Virus Type 1 (HIV-1) Infected Adults Who Are Virologically Suppressed

HIV-1-infection

United States, Puerto Rico, France, Germany, Austria, Canada
Hoffmann-La Roche

Completed

A Study to Evaluate the Efficacy and Safety of Pertuzumab + Trastuzumab + Docetaxel Versus Placebo + Trastuzumab + Docetaxel in Previously Untreated Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Metastatic Breast Cancer (PUFFIN)

Breast Cancer

China
Genentech, Inc.

Completed

A Study of Pertuzumab With High-Dose Trastuzumab for the Treatment of Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Metastatic Breast Cancer (MBC) With Central Nervous System (CNS) Progression Post-Radiotherapy

Metastatic Breast Cancer

United States
Pfizer

Terminated

Talazoparib For Neoadjuvant Treatment Of Germline BRCA1/2 Mutation Patients With Early Human Epidermal Growth Factor Receptor 2 Negative Breast Cancer

Early Breast Cancer

United States
Novartis Pharmaceuticals

Completed

Lapatinib and Bevacizumab for Metastatic Breast Cancer

Neoplasms, Breast

United States
George Washington University
Children's National Research Institute; Universitatea de Stat de Medicina si... and other collaborators

Completed

Immune Response to BCG Vaccination in Neonates Born to HIV and LTBI Infected and Non-infected Mothers (IMMUNEO)

HIV Infections | Neonatal Infection | Immune Tolerance | LTBI - Latent Tuberculosis Infection

Moldova, Republic of
Daiichi Sankyo Co., Ltd.
AstraZeneca; Daiichi Sankyo, Inc.

Completed

DS-8201a in Human Epidermal Growth Factor Receptor2 (HER2)-Expressing Colorectal Cancer (DESTINY-CRC01)

Colorectal Neoplasm

United States, Spain, Japan, Italy, United Kingdom

Search clinical trials for: epidermal transcriptome

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