Search clinical trials for: kidney safety

Total 58894 results

University of Birmingham

Active, not recruiting

Efficacy and Safety Trial of Sodium Valproate, in Paediatric and Adult Patients With Wolfram Syndrome

Wolfram Syndrome

France, United Kingdom, Poland, Spain
ChemoCentryx

Completed

Open-Label Study to Evaluate Safety and Efficacy of CCX168 in Subjects With IGA Nephropathy on Stable RAAS Blockade

Immunoglobulin A Nephropathy

United States, Sweden
Genmab

Terminated

GEN1029 (HexaBody®-DR5/DR5) Safety Trial in Patients With Malignant Solid Tumors

Renal Cell Carcinoma | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Triple Negative Breast Cancer | Non-small Cell Lung Cancer | Urothelial Cancer

United States, United Kingdom, Spain
Novartis Pharmaceuticals

Completed

Safety, Pharmacokinetics and Preliminary Efficacy Study of CFZ533 in Patients With Lupus Nephritis.

Lupus Nephritis

China, Taiwan, Hungary, Korea, Republic of, Germany, Turkey, Argentina, Russian Federation, Hong Kong, Tunisia
Cairo University
Misr International University

Completed

Comparison of Weekly Versus Every Three Weeks of Carboplatin Plus Paclitaxel in Patients With Advanced Epithelial Ovarian Cancer

Advanced Epithelial Ovarian Cancer

Egypt
Bayer

Completed

Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and Diabetic Kidney Disease (FIDELIO-DKD)

Chronic Kidney Disease

Belgium, Finland, France, China, Hong Kong, Switzerland, United States, Turkey, Greece, New Zealand, Poland, South Africa, Spain, Korea, Republic of, Portugal, Taiwan, Japan, Russian Federation, Singapore, Australia, Netherlands, ... and more
Bayer

Completed

Study to Investigate the Safety of a Drug Called Osocimab at Low and High Doses in Adult Patients With Kidney Failure Requiring Regular Hemodialysis (CONVERT)

Hemodialysis | End-stage Renal Disease | Hemodiafiltration | Prevention of Thromboembolic Events

Spain, Greece, Belgium, Russian Federation, Netherlands, Turkey, Japan, Australia, Austria, Bulgaria, Italy, Ukraine, Czechia, Israel, United States, Hungary, Lithuania, Poland, Portugal
Inmunova S.A.
Exeltis

Terminated

Phase 2/3 Study to Evaluate PK, Safety & Efficacy of INM004 in STEC Positive Pediatric Patients for Prevention of HUS

Hemolytic-Uremic Syndrome | Pediatric Kidney Disease | Bloody Diarrhea | STEC, Unspecified

Argentina
Calliditas Therapeutics AB

Active, not recruiting

Efficacy and Safety in Patients With Primary IgA Nephropathy Who Have Completed Study Nef-301 (Nefigard-OLE) (Nefigard-OLE)

Primary IgA Nephropathy

Sweden
Calliditas Therapeutics AB

Completed

Efficacy and Safety of Nefecon in Patients With Primary IgA (Immunoglobulin A) Nephropathy (Nefigard)

Primary IgA Nephropathy

United States, Australia, Taiwan, Spain, Canada, Argentina, Belarus, Belgium, Czechia, Finland, France, Germany, Greece, Italy, Korea, Republic of, Poland, Sweden, Turkey, United Kingdom
Children's Hospital of Fudan University
Shandong Provincial Hospital; Wuhan Union Hospital, China; Children's Hospital... and other collaborators

Completed

Efficacy and Safety of Rituximab in the First Episode of Pediatric Idiopathic Nephrotic Syndrome (RTXFIRPedINS)

Steroid-Sensitive Nephrotic Syndrome

China
Advanz Pharma
AMS Advanced Medical Services GmbH; APCER Life Sciences

Completed

Collection of Data of Ceftobiprole Treated Patients: Comparison of Patients With and Without Certain Diseases (RETRACE)

Hepatic Insufficiency | Renal Insufficiency | Immunosuppression

Spain, France, Germany, Italy
Bayer

Completed

Factor XI LICA to Reduce Events Such as Heart Attack and Stroke in Patients Whose Kidneys Are no Longer Able to Work as They Should and Require Treatment to Filter Wastes From the Blood: Focus is on the Safety of BAY2976217 and the Way the Body Absorbs, Distributes and Removes the Study Drug (RE-THINc ESRD)

End Stage Renal Disease Requiring Hemodialysis

Belgium, United States, Latvia, Taiwan, Germany, Japan, Spain, Canada, Bulgaria, Greece, Ukraine, Czechia, Hungary, Korea, Republic of, Russian Federation
University of Michigan
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Department...

Completed

Anticoagulation With Enhanced Gastrointestinal Safety (AEGIS) Trial (AEGIS)

Upper Gastrointestinal Bleeding

United States
Merck Sharp & Dohme LLC

Active, not recruiting

Safety and Efficacy Study of Pembrolizumab (MK-3475) as Monotherapy in the Adjuvant Treatment of Renal Cell Carcinoma Post Nephrectomy (MK-3475-564/KEYNOTE-564)

Renal Cell Carcinoma

United States, Argentina, Australia, Brazil, Canada, Chile, Colombia, Czechia, Finland, France, Germany, Ireland, Italy, Japan, Korea, Republic of, Netherlands, Poland, Russian Federation, Spain, Taiwan, United Kingdom
Alexion

Completed

Safety and Pharmacokinetic Study of Subcutaneous ALXN1720 in Participants With Proteinuria

Proteinuria

Korea, Republic of
Sanofi

Terminated

Safety, Pharmacokinetics, and Preliminary Efficacy of Isatuximab in Patients Awaiting Kidney Transplantation

Immune System Disorder

United States, Spain
Taipei Medical University Hospital

Enrolling by invitation

Evaluate the Effect and Safety of Pu Yang Wan Wu Tang and Western Medicine on Chronic Kidney Disease

Chronic Kidney Diseases

Taiwan
Endocyte

Completed

Safety and Efficacy of FolateScan (Technetium Tc 99m EC20) in Subjects With Suspected Metastatic Renal Cell Carcinoma

Metastatic Renal Cell Carcinoma

United States
Memo Therapeutics AG

Completed

Assess Safety, Tolerability and Pharmacokinetics of AntiBKV in Healthy Adult Volunteers. (SAFE KIDNEY I)

BK Virus Nephropathy

Australia
Escient Pharmaceuticals, Inc
Novotech (Australia) Pty Limited

Completed

Evaluate the Safety, Tolerability, and PK of EP547 in Healthy Subjects and Subjects With Cholestatic or Uremic Pruritus

Pruritus | Cholestasis | Kidney Failure

Australia, New Zealand
Vera Therapeutics, Inc.

Completed

A Safety, Pharmacokinetics and Efficacy Study of MAU868 for the Treatment of BK Viremia in Kidney Transplant Recipients

BK Virus Infection

United States, Canada
Bayer

Completed

Clinical Study to Evaluate the Pharmacokinetics, Safety, Tolerability and Pharmacodynamic Effects of a Single Oral 10 mg BAY1101042 Tablet Dose in Men and Woman With Renal Impairment and in Healthy Subjects

Renal Impairment

Germany
Novome Biotechnologies Inc

Terminated

Safety, Tolerability, and Pharmacodynamics of NOV-001 in Adult Subjects

Healthy Volunteers | Enteric Hyperoxaluria

United States, Canada
Incyte Corporation

Completed

Study to Evaluate the Pharmacokinetics, Safety, and Pharmacodynamics of INCB000928 in Participants With Impaired Renal Function and Hemodialysis

Hemodialysis | Renal Impairment

United States
VectivBio AG

Completed

Study of Pharmacokinetics and Safety of Apraglutide in Participants With Normal and Impaired Kidney Function.

Chronic Kidney Disease

United States
Palladio Biosciences
Centessa Pharmaceuticals plc

Terminated

Roll-over Study to Assess Safety of Lixivaptan in Participants With ADPKD Who Completed Study PA-ADPKD-303

Polycystic Kidney Disease, Adult

United States
Gilead Sciences

Terminated

Study to Evaluate the Efficacy and Safety of Remdesivir in Participants With Severely Reduced Kidney Function Who Are Hospitalized for Coronavirus Disease 2019 (COVID-19) (REDPINE)

COVID-19

Spain, United States, United Kingdom, Portugal, Brazil, South Africa
Centre Hospitalier Universitaire, Amiens

Completed

Efficacity and Safety of Metformin XR in CKD Stage 1 to 3 (METXR/CKD)

Renal Insufficiency, Chronic

France
Sanofi

Active, not recruiting

Safety and Efficacy of Hectorol in Pediatric Patients With Chronic Kidney Disease Stage 3 and 4 With Secondary Hyperparathyroidism Not Yet on Dialysis

Secondary Hyperparathyroidism-Chronic Kidney Disease

United States, Chile
Shanghai Junshi Bioscience Co., Ltd.

Active, not recruiting

Study to Evaluate the Efficacy and Safety of Toripalimab in Combination With Axitinib Versus Sunitinib Monotherapy in Advanced Renal Cell Cancer

Primary Disease: Unresectable or Metastatic Renal Cell Carcinoma Focus of the Study:PFS Assessed by IRC Per RECIST 1.1

China
Hospital do Rim e Hipertensão

Completed

Comparison of the Efficacy and Safety of Sirolimus Versus Everolimus Versus Mycophenolate in Kidney Transplantation (SEM)

Kidney Transplant Infection

Brazil
Sunshine Lake Pharma Co., Ltd.

Completed

Single and Multiple Dose Safety, Tolerability, PK and Food Effect Study of HEC73077 in Healthy Subjects

Diabetic Nephropathy

China
Kyowa Kirin, Inc.
Kyowa Kirin Co., Ltd.

Completed

Efficacy and Safety of Burosumab (KRN23) Versus Oral Phosphate and Active Vitamin D Treatment in Pediatric Patients With X Linked Hypophosphatemia (XLH)

X-Linked Hypophosphatemia

Korea, Republic of, Canada, United States, Australia, Japan, United Kingdom, Sweden
Beni-Suef University
Cairo University

Completed

N-acetyl Cysteine: the Effectiveness and Safety in a Cohort of Pediatric Patients With Chronic Kidney Disease

Chronic Kidney Diseases

Egypt
Kyowa Kirin Co., Ltd.

Active, not recruiting

Study to Assess the Safety, Pharmacokinetics and Efficacy of KRN23 in Pediatric Chinese Patients With XLH

X-linked Hypophosphatemia (XLH)

China
Kyowa Kirin Co., Ltd.

Active, not recruiting

Study to Assess the Safety, Pharmacokinetics and Efficacy of KRN23 in Adult Chinese Patients With XLH

X-linked Hypophosphatemia (XLH)

China
Palladio Biosciences
Centessa Pharmaceuticals plc

Terminated

Safety of Lixivaptan in Subjects Previously Treated With Tolvaptan for Autosomal Dominant Polycystic Kidney Disease (ALERT)

ADPKD | Polycystic Kidney Disease, Adult

United States
Apellis Pharmaceuticals, Inc.

Active, not recruiting

Phase II Study Assessing Safety and Efficacy of APL-2 in Glomerulopathies

Lupus Nephritis | IgA Nephropathy | Membranous Nephropathy | C3 Glomerulonephritis | Dense Deposit Disease

United States
Bayer

Completed

Study on the Safety of the Drug Runcaciguat and How Well it Works When Given at the Highest Dose as Tolerated by Individual Patient Whose Kidneys Are Not Working Properly and Suffering at the Same Time From High Blood Sugar and/or High Blood Pressure and a Disease of the Heart and the Blood Vessels. (CONCORD)

Chronic Kidney Disease

Spain, Belgium, Austria, Germany, Bulgaria, Denmark, Italy, Israel, Sweden, Finland, Slovakia, Ukraine, Poland
Guangdong Hengrui Pharmaceutical Co., Ltd

Completed

A Study to Evaluate the Safety, Tolerability and Pharmacokinetics Pharmacodynamics of SHR-2010 by Intravenously/Subcutaneously in Healthy Subject

IgA Nephropathy

China
Idorsia Pharmaceuticals Ltd.
Janssen Biotech, Inc.

Completed

A Research Study to Show the Effect of Aprocitentan in the Treatment of Difficult to Control (Resistant) High Blood Pressure (Hypertension) and Find Out More About Its Safety (PRECISION)

Resistant Hypertension

Spain, Israel, Czechia, United States, Canada, China, Hungary, Netherlands, Poland, United Kingdom, Germany, Australia, Belgium, Finland, France, Greece, Italy, Lithuania, Russian Federation, Ukraine
Mansoura University

Active, not recruiting

The Efficacy and Safety of Medical Expulsive Therapy After Extracorporeal Shock Wave Lithotripsy (ESWL) in Pediatric Urolithiasis

Stone, Kidney | Pediatric Disorder | Stone, Urinary | Extracorporeal Shock Wave Lithotripsy | Tamsulosin

Egypt
Korea Institute of Oriental Medicine
DongGuk University; Korean Medicine Hospital of Pusan National University; Semyung... and other collaborators

Active, not recruiting

A Multicenter Observational Study on Safety of the Herbal Medicines at Inpatient Setting

Drug Induced Liver Injury | Drug-Induced Kidney Injury | Herbal Medicine Adverse Reaction

Korea, Republic of
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Completed

Study of the Efficacy and Safety of Pegol-Sihematide for Anemia in Patients With Chronic Kidney Disease on Dialysis

Chronic Kidney Diseases

China
Talaris Therapeutics Inc.

Terminated

A Safety and Efficacy Study of FCR001 vs Standard of Care in de Novo Living Donor Kidney Transplantation (FREEDOM-1)

Transplanted Organ Rejection

United States
Iperboreal Pharma Srl

Terminated

Efficacy and Safety Assessments of a Peritoneal Dialysis Solution Containing Glucose, Xylitol, and L-Carnitine in CAPD

End Stage Renal Disease

Italy
Talaris Therapeutics Inc.

Withdrawn

A Safety and Efficacy Study of FCR001 Cell Therapy in Previously Transplanted Living Donor Kidney Recipients (FREEDOM-2)

Kidney Transplantation

United States
Instituto de Investigación Marqués de Valdecilla

Withdrawn

Efficacy, Safety, and Immunogenicity of Vaccine Reimmunization With a Third Homologous Versus Heterologous Dose Against COVID-19 in Patients Undergoing Solid Organ Transplantation. (REIN-TX)

Covid19

Spain
Celgene

Completed

An Efficacy and Safety Study of Azacitidine Subcutaneous in Combination With Durvalumab (MEDI4736) in Previously Untreated Adults With Higher-Risk Myelodysplastic Syndromes (MDS) or in Elderly Patients With Acute Myeloid Leukemia (AML)

Myelodysplastic Syndromes | Leukemia, Myeloid, Acute

Canada, Spain, United Kingdom, United States, France, Austria, Germany, Italy, Netherlands, Belgium, Portugal, Poland

Search clinical trials for: kidney safety

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