Search clinical trials for: phase I/II

Total 18510 results

University of Michigan
Michigan, State of, Licensing and Regulatory Affairs

Recruiting

MIVetsCan: Can-Coach Trial (Phase 2)

Chronic Pain

United States
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Not yet recruiting

Phase Ⅰb/Ⅱ Study of HS-10506 in Chinese Participants With Insomnia Disorder

Insomnia Disorder

China
Dianthus Therapeutics

Recruiting

A Phase 2 Study to Evaluate DNTH103 in Adults With Generalized Myasthenia Gravis (MAGIC) (MAGIC)

Myasthenia Gravis, Generalized

United States
BioMarin Pharmaceutical

Recruiting

A Phase 1/2 Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BMN 351 in Participants With Duchenne Muscular Dystrophy

Duchenne Muscular Dystrophy

Spain, Turkey, United Kingdom, Italy
Kanglin Biotechnology (Hangzhou) Co., Ltd.

Not yet recruiting

A Phase I/II Clinical Study of the KL003 Cell Injection in β-Thalassemia Major Participants

Transfusion-dependent Beta-Thalassemia

China
Inozyme Pharma

Recruiting

The SEAPORT 1 Study: Evaluation of the Safety and Tolerability of INZ-701 in Adults With End-Stage Kidney Disease Undergoing Hemodialysis

Calciphylaxis

United States
Poitiers University Hospital
Fédération Française de Cardiologie

Recruiting

CARdiAc Mri and BiOLogical samplEs at the Acute Phase of a Myocardial Infarction (CARAMBOLE) (CARAMBOLE)

Myocardial Infarction

France
Duke University
National Human Genome Research Institute (NHGRI)

Recruiting

Genomic Medicine Risk Assessment Care for Everyone - Implementation Phase (GRACE)

Liver Diseases | Cardiovascular Diseases | Cancer | Hyperthermia

United States
Latticon Antibody Therapeutics, Inc

Recruiting

A First-in-Human, Phase 1/2 Study of LAT010 in Patients With Advanced Solid Tumors (LIGHTSPEED-1) (LIGHTSPEED-1)

Advanced Solid Tumor

United States
Institute of Liver and Biliary Sciences, India

Not yet recruiting

An Open-label Randomized Controlled Trial Comparing the Role of Therapeutic Plasma-exchange in Ameliorating Secondary Organ Dysfunctions in Patients With ACLF and Develop Biomarkers of Treatment Response

Acute on Chronic Liver Failure

India
Letolab

Not yet recruiting

A Phase I Study of LTC004 Combin With FC in Patients With Advanced/Metastatic Malignancies Tumor

Adult Solid Tumor
Jiangsu Aidea Pharmaceutical Co., Ltd
Chengdu Aidea Pharmaceutical Technology Co., Ltd

Recruiting

Single Ascending Dose, Food Effects and Drug-Drug Interactions of ACC017 Tablets in Healthy Adult Participants

Healthy Adult Participants

China
Lynk Pharmaceuticals Co., Ltd

Recruiting

A Phase 3 Study of LNK01001 Capsule in Subjects With Moderate to Severe Atopic Dermatitis.

Atopic Dermatitis

China
Xencor, Inc.

Recruiting

Phase 1, Safety and Tolerability Study of XmAb®541 in Advanced Solid Tumors

Testicular Germ Cell Tumor | Ovarian Cancer | Endometrial Cancer | Ovarian Germ Cell Tumor | Germ Cell Tumor

United States
UNICANCER
Bayer

Not yet recruiting

Treatment With Darolutamide +/- Radiation Therapy for Patients With a Castration Resistant Cancer and Metastases Detected by Functional Imaging (PEACE8)

Prostatic Cancer, Castration-Resistant
The Netherlands Cancer Institute

Not yet recruiting

Chemosensitivity During Phases of the Menstrual Cycle in Breast Cancer Patients (Chemosense)

Breast Cancer

Netherlands
National Institute of Cardiology, Warsaw, Poland

Recruiting

Optimal Medical Treatment of Difficult-to-treat Hypertension (OPTIMAL-HT)

Hypertension

Poland
M.D. Anderson Cancer Center
Janssen Scientific Affairs, LLC

Not yet recruiting

PROSTATE-IQ: Parallel RandOmized STudy of Personalized Apalutamide Treatment and Evaluation to Improve Quality of Life in Post-Operative Radiation With Androgen Axis Suppression. A Phase III Multi-center Study for Men With Detectable PSA After Prostatectomy for Prostate Cancer.

Prostate Cancer | Prostatectomy | Androgen Axis Suppression

United States
University Health Network, Toronto

Recruiting

Remote Monitoring of Patient Reported Outcomes to Improve the Efficacy of the Acute Phase Radiotherapy Review Process (PROMOTE)

Breast Cancer | Prostate Cancer

Canada
Saglik Bilimleri Universitesi

Recruiting

The Effect of Electro-fetal monıtorısıon Sound on Anxiety, paın and Postpartum Bonding at the First Phase of Delivery

Labor Pain | Maternal-Fetal Relations | Delivery Fear

Turkey
Stalicla SA
National Institute on Drug Abuse (NIDA)

Recruiting

Phase1, STP7 Cocaine Drug-Drug Interaction Study

Cocaine Use Disorder

United States
S-Infinity Pharmaceuticals Co., Ltd

Not yet recruiting

A Phase I Study of XH-S003 in Healthy Volunteers

Healthy Adults

China
University of Calgary
Mitacs; Natural Sciences and Engineering Research Council, Canada

Not yet recruiting

A Novel Iron-Based Supplement for Athletes Aged 18-25: Phase II

Iron Deficiencies
Sarepta Therapeutics, Inc.

Recruiting

An Observational Study Comparing Delandistrogene Moxeparvovec With Standard of Care in Participants With Duchenne Muscular Dystrophy (ENDURE)

Duchenne Muscular Dystrophy

United States
Pliant Therapeutics, Inc.

Recruiting

A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors

Metastatic Solid Tumor

United States
AstraZeneca

Recruiting

A Phase IIb Study to Evaluate the Safety of Zibotentan/Dapagliflozin in Participants With Cirrhosis-ZEAL-UNLOCK (ZEAL UNLOCK)

Liver Cirrhosis

Italy, Japan, Germany, Belgium, Poland, Australia, United States, United Kingdom, Czechia, Slovakia
University of Exeter
Pvolve

Recruiting

The Effect of Menstrual Cycle Phase on Muscle Protein Synthesis

Muscle Protein Synthesis | Menstrual Cycle Phase

United Kingdom
Corbus Pharmaceuticals Inc.
CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd.

Recruiting

A Phase 1/2 Study to Investigate CRB-701 in Solid Tumors

Solid Tumor, Adult

United States, Spain, Turkey, United Kingdom
AstraZeneca

Recruiting

A Phase III Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin on CKD Progression in Participants With CKD and High Blood Pressure.

Chronic Kidney Disease and Hypertension

Spain, United States, Argentina, Denmark, Italy, Sweden, United Kingdom, Belgium, France, Turkey, China, Germany, Saudi Arabia, Thailand, Vietnam, Australia, Serbia, Brazil, Canada, Japan, Malaysia, Philippines, Poland, Taiwan, Greece, Is... and more
NiKang Therapeutics, Inc.

Recruiting

A Study With NKT3447 for Adults With Advanced/Metastatic Solid Tumors

Small Cell Lung Carcinoma | Gastric Cancer | Ovarian Neoplasms | Ovarian Cancer | Solid Tumor | Endometrial Neoplasms | Triple Negative Breast Cancer | Triple Negative Breast Neoplasms | Advanced Solid Tumor | Endometrial Cancer | Small-cell Lung Cancer | Platinum-resistant Ovarian Cancer | Ovarian Carcinoma | Solid... and other conditions

United States
Fujian Akeylink Biotechnology Co., Ltd.

Recruiting

A Randomized, Double-blind, Placebo-controlled Phase IIa Clinical Study to Evaluate the Safety and Efficacy of GST-HG131 Tablets in Patients With Chronic Hepatitis B

Chronic Hepatitis B

China
Instituto de Investigación Hospital Universitario...
Instituto de Salud Carlos III

Not yet recruiting

Efficacy, Safety and Cost-efficacy of a Pre-emptive Genotyping Strategy in Patients Receiving Statins (PREVESTATGx)

Cardiovascular Diseases | Dyslipidemias | Statin Adverse Reaction | Pharmacogenic Myopathy

Spain
Association des Paralysees de France (APF)
Fondation de France

Recruiting

Interest of Adapted Physical Activity by Tele-rehabilitation in Chronic Pathology - Idiopathic Scoliosis in Adolescents

Adolescent Idiopathic Scoliosis

France
Ferring Pharmaceuticals

Recruiting

A Phase 1b Proof-of-concept Trial Exploring the Effects of FE 999322 and FE 999324 in Adults With Mild to Moderate Ulcerative Colitis

Ulcerative Colitis

United States
Valerio Therapeutics

Recruiting

A Phase 1/2 Study of VIO-01 in Participants With Recurrent Solid Tumors

Breast Cancer | Prostate Cancer | Advanced or Metastatic Solid Tumors | Recurrent Ovarian Cancer

United States
Aeonvital Biomedicine

Not yet recruiting

A Phase I Study on ReT01 ACT for the Treatment of Advanced Solid Tumors

Advanced Solid Tumor
Beijing Dongfang Biotech Co., Ltd.

Not yet recruiting

A Phase 3 Study to Evaluate the Efficacy of JY09 Compared With Dulaglutide in Combination Therapy Diabetes Mellitus Type 2 Patients With Metformin

Type2 Diabetes Mellitus

China
CSPC Baike (Shandong) Biopharmaceutical Co., Ltd.

Not yet recruiting

Phase 3 Study of TG103 Injection Monotherapy in Treatment of Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus
Aummune Ltd.

Recruiting

Study of AM003 in Patients With Locally Advanced and Metastatic Solid Tumors

Solid Tumor

Israel
BrodenBio Co., Ltd.

Recruiting

A Phase 1 Study of BB102 in Participants With Advanced Solid Tumors

Advanced Solid Tumor

China
Shanxi Province Cancer Hospital

Not yet recruiting

A Single-arm, Single-center, Open-label Phase II Study of Zanubrutinib Combined With R-CHOP/R-DHAP in Newly Diagnosed Mantle CellLymphoma Patients (Z+RCHOP/RDHAP)

Mantle Cell Lymphoma

China
Nanjing Immunophage Biotech Co., Ltd
Zhejiang Hospital

Recruiting

Phase 1 Study for IPG11406 in Health Volunteer

Inflammatory Bowel Diseases

China
Shanghai Pulmonary Hospital, Shanghai, China

Recruiting

Neoadjuvant Therapy With Toripalimab and JS004 Combined With Etoposide and Platinum Chemotherapy for Limited-stage Small Cell Lung Cancer : A Phase 2 Trial

Limited Stage Small Cell Lung Cancer

China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not yet recruiting

Randomized, Open, Controlled, Multicenter Phase III Clinical Study of Fluzoparib in Combination With Apatinib Versus Investigator-Selected Chemotherapy for HRD-Positive/HER2-negative Advanced Breast Cancer

Breast Cancer

China
UTC Therapeutics Inc.
Peking University Cancer Hospital & Institute

Recruiting

Phase 1 Study of UCMYM802 Injection in Mesothelin-positive Advanced Malignant Solid Tumors

Colorectal Cancer | Pancreatic Cancer | Rectal Cancer | Malignant Mesothelioma | Bile Duct Cancer | Breast Cancer Female | Ovary Cancer

China
Central Hospital, Nancy, France
Institut National de la Santé Et de la Recherche Médicale, France; University... and other collaborators

Not yet recruiting

Impact on Quality of Life of Symptoms Routine E-monitoring Among Dialysis Patients. (F-SWIFT)

End Stage Renal Disease

France
The First Affiliated Hospital with Nanjing Medical...
Anhui Provincial Cancer Hospital; Affiliated Hospital of Jiangnan University; The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School and other collaborators

Recruiting

The Dosing Regimen of Pyrotinib in HER2-positive Advanced First-line Breast Cancer: a Phase II Clinical Study

Breast Cancer

China
Beijing Dongfang Biotech Co., Ltd.

Not yet recruiting

A Phase 3 Study to Evaluate the Efficacy of JY09 Compared With Placebo in T2DM Patients

Type 2 Diabetes Mellitus

China
Iambic Therapeutics, Inc

Recruiting

A Phase 1/1b Study of IAM1363 in HER2 Cancers

HER2 Mutation-Related Tumors

United States
University of North Carolina, Chapel Hill
National Institute of Mental Health (NIMH)

Not yet recruiting

Causal Role of Top-Down Theta Oscillations in Prioritization

Epilepsy | Working Memory

United States

Search clinical trials for: phase I/II

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