Search clinical trials for: xerostomia

Total 525 results

Boston Children's Hospital

Completed

Effect of Childhood Radioiodine Therapy on Salivary Function

Hyperthyroidism | Xerostomia | Thyroid Cancer

United States
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Terminated

Chemo/XRT +/- Amifostine to Assess Outcomes Related to Xerostomia, Mucositis, & Dysphagia

Head and Neck Cancer | Dysphagia | Mucositis | Xerostomia

United States
Kissei Pharmaceutical Co., Ltd.

Completed

A Phase III Study of KCT-0809 in Dry Eye Patients With Sjögren's Syndrome

Dry Eye With Sjögren's Syndrome

Japan
Tung Wah Hospital

Unknown

Is Sjögren's Syndrome Associated With Meibomian Gland Dysfunction ?

Meibomian Gland Dysfunction | Sjögren's Syndrome

China
Derk Jan Jager

Unknown

Endoscopic Treatment of Salivary Glands Affected by Sjögren's Syndrome

Sjögren's Syndrome

Netherlands
Loma Linda University

Withdrawn

Saliva, Hyperbaric Oxygen Therapy, & Gland Function: A Prospective Study (SHOTGUN)

Xerostomia | Osteoradionecrosis of the Jaw

United States
Federal University of São Paulo

Completed

Resistance Exercise in Woman With Primary Sjörgen Syndrome.

Primary Sjögren Syndrome
University Hospital, Brest

Unknown

Inflammatory Myopathies in Primary Sjögren's Syndrome (AMISS)

Primary Sjögren Syndrome

France
Novartis Pharmaceuticals

Withdrawn

Study of Pharmacodynamic Effects of VAY736 in Patients With Primary Sjögren's Syndrome

Primary Sjögren's Syndrome
Norwegian University of Science and Technology
St. Olavs Hospital; Helse Midt-Norge

Completed

Acute and Longlasting Side Effects Caused by Radiotherapy in the Head and Neck Area

Head and Neck Cancer

Norway
Università degli Studi di Sassari

Completed

Effect of a Self-adhering Material in Dental Hypersensitivity

Dentin Sensitivity | Xerostomia

Italy
University of Copenhagen
Rigshospitalet, Denmark

Completed

Effect of B-cell Depletion in Patients With Primary Sjögren's Syndrome

Fatigue | Keratoconjunctivitis Sicca | Primary Sjögren's Syndrome | Xerostomia | Hyposalivation

Denmark
IRCCS Azienda Ospedaliero-Universitaria di Bologna
University of Bologna; Centro Nazionale Sangue; Regione Emilia-Romagna

Unknown

Blood Based Eyedrops From Different Sources in the Treatment of Severe Keratopathy

Sjogren's Syndrome | Keratopathy | GVHD - Graft-Versus-Host Disease

Italy
Lovisenberg Diakonale Hospital
University of Oslo

Completed

A Randomized Controlled Trial Evaluating the Effectiveness of a Salvia-based Mouthwash in Palliative Care

Xerostomia | Terminal Illness

Norway
NHS Greater Glasgow and Clyde
University of Glasgow; Lamellar Biomedical Ltd

Completed

A Study of Patients With Dry Mouth and Sticky Saliva During Radiotherapy

Xerostomia

United Kingdom
University of Zagreb

Completed

Low Level Laser Therapy for Hyposalivation

Hyposalivation

Croatia
Peking Union Medical College Hospital

Unknown

Study of Iguratimod in Sjögren's Syndrome

Sjogren's Syndrome

China
The Cleveland Clinic
Bristol-Myers Squibb

Withdrawn

Abatacept for Patients With Inflammatory Arthritis Associated With Sjögren's Syndrome: an Open-Label Phase II Study

Rheumatoid Arthritis | Inflammatory Arthritis | Primary Sjogren's Syndrome | Secondary Sjogren's Syndrome

United States
Dana-Farber Cancer Institute
National Cancer Institute (NCI); AstraZeneca; MedImmune LLC

Completed

Randomized Amifostine For SCCHN

Head and Neck Cancer | Mucositis | Xerostomia | Radiation Toxicity | Chemotherapeutic Agent Toxicity

United States
Nihon University

Completed

Deterioration of Resilient Denture Liners and Patient Characteristics

Menopause | Xerostomia | Kidney Disease
University of Sao Paulo

Unknown

Effect of Pilocarpine in Patients With Xerostomia

Xerostomia

Brazil
Thomas Kuhnt
Verband Deutscher Druckkammerzentren

Terminated

Hyperbaric Oxygen for the Treatment of a Dry Mouth Which Occurred After Radiotherapy

Radiation-induced Xerostomia

Germany
Bedford Hospital NHS Trust
Moorfields Eye Hospital NHS Foundation Trust; University Hospitals Bristol... and other collaborators

Unknown

Treating Dry Eyes and Corneal Ulcers With Fingerprick Autologous Blood (FAB)

Dry Eyes | Sjogren's Disease With Dry Eyes | Persistent Corneal Epithelial Defects | Chronic Corneal Ulcers

United Kingdom
Swedish Orphan Biovitrum
Amgen

Completed

Palifermin for the Reduction of Oral Mucositis in Patients With Locally Advanced Head and Neck Cancer

Head and Neck Cancer | Mucositis | Stomatitis | Solid Tumors | Squamous Cell Carcinoma
Kaohsiung Medical University

Unknown

Efficacy and Safety of Mycophenolate Mofetil in subjectswithSjogren's Syndrome

Sjogren's Syndrome
University of Rochester

Terminated

Effects of Sustained Reading on the Ocular Surface

Dry Eye Syndromes | Sjogren's Syndrome

United States
Universidade Estadual de Londrina

Completed

Package of Mentholated Measures for the Relief of Thirst in the Anesthesia Recovery Room

Thirst | Mouth Dryness | Irritation Lips

Brazil
Samira Tatiyama Miyamoto
Federal University of São Paulo; Newcastle University

Completed

Aerobic Exercise in Primary Sjögren's Syndrome (AEPSS)

Sjogren's Syndrome

Brazil
Centre Hospitalier Universitaire de Besancon

Completed

Frequency of Xerostomia and Their Management in Upper Aerodigestive Tract Cancer Patients After the End of Radiotherapy (XEROSTOMIA)

Head and Neck Neoplasms

France
China Medical University Hospital
China Medical University, China; Chang Gung Memorial Hospital; National Research...

Unknown

Modulation of Immunity-related Gene Expression Under the Chinese Herbal Formula SS-1 Treatment for Sjögren's Syndrome

Sjögren's Syndrome

Taiwan
Shiraz University of Medical Sciences
Shahid Beheshti University of Medical Sciences

Completed

Efficacy of Traditional Persian Medicine Preparation Versus Artificial Saliva for Radiation Induced Xerostomia

Xerostomia | Head and Neck Cancers
Bedford Hospital NHS Trust

Unknown

Optical Coherence Tomography of Ocular Structures in Epiphora and Dry Eye Syndrome. (OCT)

Epiphora | Dry Eye Syndrome | Sjögren's Syndrome
Mayo Clinic
National Cancer Institute (NCI)

Terminated

Electroacupuncture in Treating Chronic Dry Mouth Caused By Radiation Therapy in Patients With Head and Neck Cancer

Head and Neck Cancer | Xerostomia | Radiation Toxicity

United States
Universidad de Granada
Instituto de Salud Carlos III

Completed

Drug-induced Xerostomia. Evaluation of Malic Acid 1%, Salivary Mucins and Buffering Capacity

Depression | Hypertension | Xerostomia

Spain
AHS Cancer Control Alberta
Cross Cancer Institute

Unknown

A Pilot Study to Evaluate the Feasibility of Combining Submandibular Salivary Gland Tx & IMRT Tomo to Reduce Xerostomia

Head and Neck Cancer

Canada
Guang'anmen Hospital of China Academy of Chinese...

Unknown

Acupuncture for Primary Sjögren Syndrome

Sjogren's Syndrome

China
AHS Cancer Control Alberta
Cross Cancer Institute

Completed

Nutritional Status and Barriers to Dietary Intake in Head and Neck Cancer Patients

Head and Neck Cancer

Canada
Khon Kaen University
General Drugs House Co.,LTD.; Ubon Ratchathani Cancer Hospital, Ubon Ratchathani

Completed

Topical/Oral Melatonin for Preventing Concurrent Radiochemotherapy Induced Oral Mucositis/Xerostomia Cancer Patients

Head and Neck Cancer

Thailand
AHS Cancer Control Alberta
Cross Cancer Institute

Completed

Xerostomia in Head and Neck Cancer Patients Receiving Radiation as the Primary Treatment Versus Patients Who Will Not Have Such a Procedure

Head and Neck Cancer

Canada
University of Sao Paulo

Unknown

Exercise in Sjogren, Myositis and Takayasu's Arteritis

Myositis | Primary Sjogren´s Syndrome

Brazil
Göteborg University
Vastra Gotaland Region; Vinnova

Completed

The Effect of Probiotic Streptococci and pH-rising Components on the Oral Microbial Flora

Hyposalivation

Sweden
Chang Gung Memorial Hospital
China Medical University, China; China Medical University Hospital; National... and other collaborators

Unknown

Evaluation of the Efficacy and the Mechanism of Chinese Herbal Formula SS-1 for Sjögren's Syndrome (SS-1)

Sjögren's Syndrome

Taiwan
Michigan Cornea Consultants, PC
Kresge Eye Institute

Completed

Comparative Study of Thymosin Beta 4 Eye Drops vs. Vehicle in the Treatment of Severe Dry Eye

Dry Eye | Sjogren's Syndrome | Graft vs. Host Disease

United States
National Institute of Dental and Craniofacial Research...

Terminated

Pilot Study of Raptiva to Treat Sjogren's Syndrome

Sjogren's Syndrome

United States
University Hospital, Brest

Completed

Evaluation of the Reproducibility Inter-observer of the Ultrasound Anomalies of the Salivary Glands in Sjogren's Disease (ETREINTE)

Sjogren's Disease
Institut National de la Santé Et de la Recherche...
Centre Hospitalier Universitaire Dijon; Centre Hospitalier Universitaire de... and other collaborators

Withdrawn

Development of a Milk Product Substitution for Patients Suffering From Xerostomia Caused by Medication (LactoXeros)

Xerostomia

France
University of Rochester
Bausch & Lomb Incorporated

Completed

Evaluation of Ocular Surface Inflammatory Mediators Effected by Lotemax

Sjogren's Disease

United States
Helse Stavanger HF
University of Oslo; University of Stavanger

Completed

Fatigue and Interleukin-1 (IL-1) Blockade in Primary Sjøgrens Syndrome

Fatigue | Primary Sjogren

Norway
Charite University, Berlin, Germany

Completed

Low Dose Cyclosporin A in Primary Sjögren Syndrome (CYPRESS)

Sjögren´s Syndrome

Germany
University of Michigan

Completed

Oral Health and Oral Health-Related Quality of Life in Early Stage Breast Cancer Survivors

Breast Cancer | Xerostomia

United States

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