Clinical Trials Sponsored by Action Cancer

Total 68883 results

Actelion

Completed

Clinical Study to Assess the Safety, Tolerability and Efficacy of Macitentan in Subjects With Inoperable Chronic Thromboembolic Pulmonary Hypertension (MERIT-2)

Chronic Thromboembolic Pulmonary Hypertension

Poland, Ukraine, United Kingdom, China, Russian Federation, Belgium, Germany, Thailand, Hungary, France, Lithuania, Czechia, Mexico, Switzerland, Turkey
Actelion

Completed

ACT-128800 in Patients With Moderate to Severe Chronic Plaque Psoriasis

Psoriasis

Austria, Belgium, Bulgaria, Czechia, Denmark, France, Hungary, Italy, Lithuania, Romania, Russian Federation, Slovakia, Spain, Sweden, Switzerland, Ukraine, United Kingdom
Actelion

Completed

A Study of Two Different Test Formulations Compared to the Reference Formulation of Macitentan in Healthy Adult Participants

Healthy

Belgium
Actelion

Completed

A Study of Two Macitentan Formulations in Healthy Adult Participants

Healthy

Belgium
Actelion

Completed

Safety and Efficacy of Miglustat in Chinese NPC Patients

Niemann-Pick Disease, Type C

China
Actelion

Completed

A 2-part Study to Investigate the Effect of Macitentan in Healthy Male Participants

Healthy

Belgium
Actelion

Completed

A Study of Fixed Dose Combination of Macitentan/Tadalafil (10 mg/20 mg) Compared to the Reference Free Combination of Macitentan and Tadalafil in Healthy Adult Participants

Healthy

United States
Actelion

Completed

FUTURE 3 Study Extension (FUTURE 3 Ext)

Pulmonary Arterial Hypertension

United States, Australia, Belarus, China, Czechia, France, Germany, Hungary, India, Israel, Italy, Mexico, Poland, Russian Federation, Serbia, South Africa, Spain, Ukraine
Actelion

Completed

Clinical Study to Assess the Efficacy and Safety of Macitentan in Patients With Pulmonary Hypertension After Left Ventricular Assist Device Implantation (SOPRANO)

Pulmonary Hypertension

United States
Sciton

Completed

Hybrid Fractional Laser for Treatment of Off Face Body Skin Quality

Skin Laxity

United States
Sciton

Completed

Hybrid Fractional Laser for Symptoms of Genitourinary Syndrome of Menopause

Sexual Dysfunction | Vaginal Atrophy | Vaginal Dryness | Dyspareunia | Chronic UTI

United States
Sciton

Completed

Hybrid Fractional Laser Treatment for Symptoms of Urinary Incontinence

Urinary Incontinence | Stress Urinary Incontinence | Urge Incontinence

United States
Actelion

Completed

PORtopulmonary Hypertension Treatment wIth maCitentan - a randOmized Clinical Trial (PORTICO)

Portopulmonary Hypertension

United States, France, Germany, United Kingdom, Brazil, Czechia, Spain
Actelion

Terminated

Clinical Study Evaluating the Effects of First-line Oral cOmbination theraPy of maciTentan and tadalafIl in Patients With Newly Diagnosed pulMonary Arterial Hypertension (OPTIMA) (OPTIMA)

Pulmonary Arterial Hypertension

France
Actelion

Completed

Extension of the Psychometric Validation Study ORCHESTRA in Patients With PAH

Pulmonary Arterial Hypertension

Spain, France, Italy
Actelion

Completed

Safety Study of the Switch From Oral Selexipag to Intravenous Selexipag in Subjects With Stable Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

United States, Germany
Actelion

Terminated

Clinical Study of Macitentan in Patients With PAH to Psychometrically Validate PAH-SYMPACT Instrument (SYMPHONYext)

Pulmonary Arterial Hypertension

United States
Actelion

Completed

Efficacy and Safety of Cadazolid Versus Vancomycin in Subjects With Clostridium Difficile-associated Diarrhea

Clostridium Difficile Infection

United States, Belgium, Israel, Argentina, Brazil, Canada, Chile, Croatia, Czechia, Greece, Hungary, Korea, Republic of, Romania, Slovakia
Actelion

Terminated

A Pulmonary Arterial Hypertension Study With Macitentan to Validate the PAH-SYMPACT™ in France, Italy and Spain (ORCHESTRA)

Pulmonary Arterial Hypertension

Spain, France, Italy
Actelion

Terminated

Clinical Study on Macitentan, RT and TMZ Concurrent Therapy Followed by Maintenance Macitentan and TMZ in Newly Diagnosed Glioblastoma

Glioblastoma

United States
Actelion

Completed

Clinical Study to Investigate Effect of Macitentan on Riociguat Pharmacokinetics

Healthy Subjects

Germany
Actelion

Completed

Clinical Study to Investigate the Effect of Macitentan on the Concentrations of Rosuvastatin in the Blood of Healthy Male Subjects

Healthy Subjects

Germany
Actelion

Completed

Effects of Two Dosing Regimens of Bosentan in Children With Pulmonary Arterial Hypertension (FUTURE 3)

Pulmonary Arterial Hypertension

United States, Australia, Belarus, China, Czechia, France, Germany, Hungary, India, Israel, Italy, Mexico, Netherlands, Poland, Russian Federation, Serbia, South Africa, Spain, Ukraine
Actelion

Completed

Efficacy, Safety and Tolerability of Cadazolid in Subjects With Clostridium Difficile Associated Diarrhea (CDAD)

Clostridium Difficile Infection

United States, Canada, Germany, Italy, Sweden, United Kingdom
Actelion

Completed

Absolute Bioavailability of a Single Oral Dose of Selexipag in Healthy Subjects

Healthy Subjects

France
Actelion

Completed

Potential Pharmacokinetic Interaction Between Selexipag and Midazolam in Healthy Male Subjects

Healthy Subjects

France
Actelion

Completed

BREATHE 5-OL: Tracleer (Bosentan) in Patients With Pulmonary Arterial Hypertension Related to Eisenmenger Physiology

Pulmonary Arterial Hypertension

Canada, United Kingdom, Italy, United States, Netherlands, Australia, Austria, Belgium, France, Germany, Spain
Actelion

Completed

Bosentan in Children With Pulmonary Arterial Hypertension (FUTURE-1)

Pulmonary Arterial Hypertension

United States, France, Netherlands, Italy, Germany, Switzerland, United Kingdom
Actelion

Completed

Comparison of the Pharmacokinetic Properties of Two Tablet Formulations of Macitentan in Healthy Adults

Healthy Subjects

Czech Republic
Actelion

Terminated

Effects of Ventavis in Patients With Pulmonary Hypertension (PH) Secondary to Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease | Pulmonary Hypertension

United States, Spain, France
Actelion

Completed

Iloprost Power 15 in Pulmonary Arterial Hypertension (PROWESS 15)

Pulmonary Arterial Hypertension

United States, Austria, Germany
Actelion

Completed

Open Label Extension Study in Patients With Idiopathic Pulmonary Fibrosis Who Completed Protocol AC-052-321/ BUILD 3 / NCT00391443 (BUILD OL)

Idiopathic Pulmonary Fibrosis

United States, France, Spain, Korea, Republic of, United Kingdom, Belgium, Japan, Australia, Canada, Czech Republic, Germany, Ireland, Israel, Italy, Switzerland
Actelion

Completed

BUILD 3: Bosentan Use in Interstitial Lung Disease (BUILD 3)

Idiopathic Pulmonary Fibrosis

United States, France, Spain, Korea, Republic of, Canada, United Kingdom, Australia, Belgium, Netherlands, Japan, Germany, Czech Republic, Italy, Switzerland, Austria, Croatia, Ireland, Israel, Serbia
Actelion

Terminated

Ventavis® Registry Protocol (RESPIRE)

Pulmonary Arterial Hypertension

United States
Actelion

Completed

Two Period / Two Treatment Cross-over to Assess the Effect of Florastor® on Gastrointestinal Tolerability, Safety, and PK in Healthy Subjects Receiving Zavesca®

Diarrhea

Canada
Actelion

Completed

Mass Balance, Pharmacokinetics, and Metabolism of 14C-labeled ACT-128800 Administered to Healthy Male Subjects

Pharmacokinetics

Switzerland
Actelion

Completed

Macitentan Use in an Idiopathic Pulmonary Fibrosis Clinical Study (MUSIC)

Idiopathic Pulmonary Fibrosis

United States, Israel, Spain, Australia, France, Canada, Turkey, Germany, Italy, South Africa, Slovenia, Sweden
Actelion

Completed

Study to Assess the Effect of Macitentan on the Electrocardiogram (ECG) in Healthy Male and Female Subjects

Healthy

Germany
Actelion

Completed

Bosentan in Systemic Sclerosis (HOME)

Systemic Sclerosis | Digital Ulcers

Netherlands
Actelion

Completed

Digital Ulceration (CAP)

Systemic Sclerosis | Digital Ulcers

Belgium, Spain, United Kingdom, Germany, Italy, Portugal, France, Israel, Netherlands, Turkey, Austria, Switzerland, Greece, Czech Republic, Norway
Actelion

Terminated

Iloprost Power Disc-15 in Pulmonary Arterial Hypertension (INHALE-15)

Pulmonary Arterial Hypertension

United States
Actelion

Completed

Bosentan in Patients With Inoperable Chronic Thromboembolic Pulmonary Hypertension (CTEPH) (BENEFIT OL)

Pulmonary Hypertension

United States, Canada, Australia, Germany, Italy, United Kingdom, France, Austria, Belgium, Czech Republic, Netherlands, Poland, Spain
Actelion

Completed

Efficacy and Safety of Oral Bosentan in Patients With Idiopathic Pulmonary Fibrosis (BUILD 1)

Idiopathic Pulmonary Fibrosis

United States, United Kingdom, Switzerland, Israel, Canada, France, Germany, Italy
Actelion

Terminated

Efficacy and Safety of Bosentan in Sickle Cell Disease (SCD) Patients Diagnosed With Pulmonary Hypertension (PH) (ASSET-2)

Pulmonary Hypertension

United States, France, United Kingdom, Netherlands
Actelion

Completed

Trial of Iloprost Inhaled Solution as Add-On Therapy With Bosentan in Subjects With Pulmonary Arterial Hypertension (PAH)

Pulmonary Arterial Hypertension | Pulmonary Hypertension | Ayerza Syndrome

United States
Actelion

Completed

Miglustat in Niemann-Pick Type C Disease

Niemann-Pick Type C Disease

United States
Actelion

Terminated

Efficacy and Safety of Bosentan in Sickle Cell Disease (SCD) Patients With Pulmonary Arterial Hypertension (PAH)

Pulmonary Hypertension

United States, France, United Kingdom, Netherlands
Actelion

Completed

The Effect of Tracleer® on Male Fertility

Hypertension, Pulmonary

United States, Australia, Brazil, Czech Republic, Hungary
Sciton

Recruiting

Laser Treatment for Lichen Sclerosus

Lichen Sclerosus Lesion

Canada
Sciton

Recruiting

Evaluation of Broadband Light Treatment for Solar Lentigines

Solar Lentigo

United States

Clinical Trials Sponsored by Action Cancer

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Russia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

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