Clinical Trials Sponsored by Aeglea Biotherapeutics

Total 611 results

Laboratorio Elea Phoenix S.A.

Completed

Racotumomab in Patients With High-risk Neuroblastoma

Neuroblastoma

Argentina
Laboratorio Elea Phoenix S.A.

Terminated

Recurrent and Nonrecurrent Condyloma Treatment

Recurrent Condyloma | Nonrecurrent Condyloma

Argentina
PersonGen BioTherapeutics (Suzhou) Co., Ltd.
Department of Immunology, The Fourth Hospital of Hebei Medical University

Recruiting

A Clinical Trial of TAA06 Injection in Advanced Solid Tumors

Malignant Melanoma, Lung Cancer, or Colorectal Cancer

China
Guangdong 999 Brain Hospital
Jinan University Guangzhou; Beijing Tricision Biotherapeutics Inc; Trinomab Biotech...

Completed

Personalized Cellular Vaccine for Glioblastoma (PERCELLVAC) (PERCELLVAC)

Glioblastoma

China
Guangdong 999 Brain Hospital
Jinan University Guangzhou; Beijing Tricision Biotherapeutics Inc; Trinomab Biotech...

Completed

Personalized Cellular Vaccine for Recurrent Glioblastoma (PERCELLVAC2) (PerCellVac2)

Glioblastoma

China
Anglia Ruskin University
Medtronic; Mid Essex Hospital NHS Trust

Completed

Comparison of PEAK PlasmaBlade™ to Conventional Diathermy in Abdominal Based Free Flap Breast Reconstruction

Breast Cancer | Breast Reconstruction

United Kingdom
Angela Bianco

Completed

Pain Perception During Chorionic Villus Sampling

Chorionic Villi Sampling

United States
Angela Oxenius
University Hospital, Zürich

Completed

Assessment of Left and Right Ventricular Function in Patients With Ebstein Anomaly With Different Echocardiographic Methods

Ebstein Anomaly

Switzerland
Angela Bianco
Icahn School of Medicine at Mount Sinai

Completed

Dental Support Device in the Second Stage of Labor

Labor

United States
Rob Erskine
University of East Anglia

Completed

Resistance Exercise and Hydrolyzed Collagen Supplementation

Diet, Food, and Nutrition

United Kingdom
Dr Anthony Hobson
Anglia Ruskin University

Completed

GI Effects of Iron in Healthy Volunteers

Iron-deficiency | Microbial Colonization | Iron Deficiency Anemia | Iron Deficiency Anemia Treatment

United Kingdom
Mid and South Essex NHS Foundation Trust
Anglia Ruskin University

Completed

Mirror Box Imaging Study

Stroke

United Kingdom
Mid and South Essex NHS Foundation Trust
Anglia Ruskin University

Completed

Care After Resuscitation (CARE)

Cardiac Arrest

United Kingdom
Mid and South Essex NHS Foundation Trust
Anglia Ruskin University

Completed

The Impact of Post Stenting Balloon Dilatation on Coronary Microcirculation in STEMI Patients Undergoing PPCI (POSTDILSTEMI)

ST-elevation Myocardial Infarction (STEMI)

United Kingdom
Mid and South Essex NHS Foundation Trust
Anglia Ruskin University

Completed

Efficacy, Safety and Efficiency of the nMARQ Pulmonary Vein Isolation System in Paroxysmal Atrial Fibrillation

Paroxysmal Atrial Fibrillation

United Kingdom
University of East Anglia
Royal Brompton & Harefield NHS Foundation Trust

Completed

The Nitrite and Coronary Flow Study

Cardiovascular Diseases | Hypoxia | Vasodilation

United Kingdom
H. Lee Moffitt Cancer Center and Research Institute
Bristol-Myers Squibb; Iovance Biotherapeutics, Inc.; Prometheus Inc.

Completed

Combining PD-1 Blockade, CD137 Agonism and Adoptive Cell Therapy for Metastatic Melanoma

Skin Cancer | Melanoma (Skin)

United States
Prometic Biotherapeutics, Inc.
Vanderbilt University Medical Center; Cedars-Sinai Medical Center; Indiana Hemophilia...

No longer available

A Single-patient Study of Repeat-dose Administration of Prometic Plasminogen (Human) Intravenous

Hypoplasminogenemia
PersonGen BioTherapeutics (Suzhou) Co., Ltd.
Tianjin Medical University Cancer Institute and Hospital; Shandong Cancer Hospital...

Recruiting

TAA06 Injection in the Treatment of Patients With B7-H3-positive Relapsed/ Refractory Neuroblastoma

B7-H3-positive Relapsed/ Refractory Neuroblastoma

China
University of East Anglia
Norfolk and Suffolk NHS Foundation Trust

Recruiting

The Efficacy of a Growth-Mindset Intervention for Adolescents: A Randomised Controlled Trial

Depression, Anxiety | Anxiety Disorders and Symptoms | Adolescent - Emotional Problem

United Kingdom
Mid and South Essex NHS Foundation Trust
Anglia Ruskin University

Completed

The Effect of GRAVITY on Physiological Measurements During Invasive Coronary Angiography and Intervention (GRAVITY)

Coronary Artery Disease

United Kingdom
Mid and South Essex NHS Foundation Trust
Anglia Ruskin University

Completed

Right Ventricle (RV) Markers of Future Pacing Induced Ventricular Dysfunction - Pilot

Sick Sinus Syndrome

United Kingdom
Mid and South Essex NHS Foundation Trust
Anglia Ruskin University

Completed

Southend Imaging Study (SIS)

Cognition Disorders

United Kingdom
Mid and South Essex NHS Foundation Trust
Anglia Ruskin University

Not yet recruiting

STASSH - TRAUMA - Absorbable vs Non-Absorbable Sutures in Trauma Hand Surgery (STASSH-TRAUMA)

Scar | Suture, Complication | Symptoms and Signs | Skin Infection | Hand Infection
Rob Erskine
University of East Anglia

Completed

Acute Resistance Exercise and Hydrolyzed Collagen Supplementation

Diet | Nutrition | Food

United Kingdom
Anglia Ruskin University
Mid and South Essex NHS Foundation Trust

Unknown

The Oscillation of Crystalline and Intraocular Lenses

Cataract | Pseudoexfoliation Syndrome | Ectopia Lentis | Marfan's Syndrome With Ocular Manifestations | Phakodonesis

United Kingdom
Norfolk and Suffolk NHS Foundation Trust
University of East Anglia

Completed

INCLUDE: Using Lived Experience to Improve Mental Health Diagnosis v1 (INCLUDE)

Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse) | Schizophrenia | Bipolar Disorder | Generalised Anxiety Disorder

United Kingdom
University of East Anglia
Harvard School of Public Health (HSPH)

Completed

The Health Effects of Blueberry Anthocyanins in Metabolic Syndrome (the CIRCLES-study) (CIRCLES)

Insulin Resistance | Metabolic Syndrome X

United Kingdom, United States
University of East Anglia
Norfolk and Suffolk NHS Foundation Trust

Unknown

The Feasibility of a Novel Intervention for At Risk Mental State

At Risk Mental State | Attenuated Psychotic Symptoms

United Kingdom
PersonGen BioTherapeutics (Suzhou) Co., Ltd.
Anhui Provincial Hospital; The First People's Hospital of Hefei; Hefei Binhu...

Unknown

CAR-T Cell Immunotherapy in CD19 Positive Relapsed or Refractory Leukemia and Lymphoma

Follicular Lymphoma | Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | Acute Lymphocytic Leukemia | Diffuse Large Cell Lymphoma | B-cell Prolymphocytic Leukemia

China
University of Cagliari
Angela Sanna; Micaela Porta; Paolo Tacconi; Chiara Pau

Completed

Cerebellar Transcranial Direct Current Stimulation in Spinocerebellar Ataxia 38

Spinocerebellar Ataxias

Italy
Angela Bianco
Stryker Nordic

Terminated

Preoperative Application of Chlorhexidine to Reduce Infection With Cesarean Section After Labor (PRACTICAL)

Cesarean Section | Surgical Site Infection | Nosocomial Infection

United States
Jacob Gallagher
Iowa State Fraternal Order of Eagles

Completed

Physical Activity Intervention Tailored for Rural Men

Sedentary Behavior | Physical Inactivity | Weak; Muscle

United States
University of East Anglia
National Institute for Health Research, United Kingdom

Unknown

Investigating Usability of c-SIGHT in the Homes of Brain Injury Survivors (c-SIGHT)

Stroke | Brain Injuries | Spatial Neglect | Attention Deficit

United Kingdom
University of East Anglia
National Institute for Health Research, United Kingdom

Unknown

Preop CPET Testing and Exercise Training in Colorectal Patients

Colorectal Neoplasms

United Kingdom
University of East Anglia
University of Washington; Fred Hutchinson Cancer Center

Unknown

An Acute Human Intervention With Flavonoid to Investigate Absorption, Metabolism and Excretion (COB)

Pharmacokinetics of Flavonoids in Humans

United Kingdom
Laboratorio Elea Phoenix S.A.
Syneos Health

Recruiting

Double-blind Study to Evaluate the PK, Efficacy, Safety and Immunogenicity of MB12 Versus Keytruda® in Stage IV NSCLC

Non Small Cell Lung Cancer Metastatic

Georgia, Chile, Argentina
Mid and South Essex NHS Foundation Trust
University of East Anglia; National Institute for Health Research, United Kingdom and other collaborators

Completed

Anakinra vs. Steroids for the Treatment of Gout Attacks in Patients With Renal Disease (ASGARD): A Feasibility Study (ASGARD)

Chronic Kidney Diseases | Gout

United Kingdom
Army Health Branch, British Army
University of East Anglia; Osteolabs, GEOMAR

Recruiting

The Effect of Calcium Intake on Calcium and Bone Metabolism During Load Carriage in Women (En-Bone)

Calcium Deficiency

United Kingdom
Children's Hospital of Philadelphia
University of Pennsylvania; Eagles Autism Challenge, Inc

Completed

Autism and Disruptive Behavior Trial

Child Behavior Problem | ASD

United States
Norfolk and Norwich University Hospitals NHS Foundation...
University of East Anglia

Recruiting

Poly-unsaturated Fats for Improving Nasal Polyps and Asthma (PUFFIN)

Asthma

United Kingdom
Norfolk and Norwich University Hospitals NHS Foundation...
University of East Anglia

Completed

Cessation of Smoking Trial in the Emergency Department (CoSTED)

Smoking Cessation | Electronic Cigarette Use | Vaping | E-Cig Use

United Kingdom
Norfolk and Norwich University Hospitals NHS Foundation...
University of East Anglia

Completed

Coronary Artery Endothelial Dysfunction With Drug Coated Balloons (SPARTAN-VM)

Coronary Artery Disease | Endothelial Dysfunction | Ischaemic Heart Disease

United Kingdom
Norfolk and Norwich University Hospitals NHS Foundation...
University of East Anglia

Completed

Defining Outcome Measures for Acute Charcot Neuroarthropathy in Diabetes and Their Use in Assessing Clinical Management (CADOM)

Diabetes

United Kingdom
Papworth Hospital NHS Foundation Trust
Anglia Ruskin University; Hinchingbrooke Healthcare NHS Trust

Completed

Prevalence of Obstructive Sleep Apnoea in Glaucoma (POSAG)

Open Angle Glaucoma | Obstructive Sleep Apnoea

United Kingdom
University of East Anglia
Medical Research Council Cognition and Brain Sciences Unit

Unknown

The STAGE Study for Bipolar Disorder

Bipolar Disorder

United Kingdom
Liaquat University of Medical & Health Sciences
University of East Anglia; Activ'inside

Recruiting

Effects of a Standardised Saffron Extract Supplementation on Symptoms Associated With Perimenopause in Healthy Women

Perimenopausal Disorder

Pakistan
University of East Anglia
National Institute for Health Research, United Kingdom

Completed

Estimating Quality of Life in People With Asthma

Asthma

United Kingdom
Beacon Hill Academy
Anglia Ruskin University; The Music Therapy Charity Ltd

Withdrawn

Improvised Music to Enhance Intensive Interaction Version 1

Child Development Disorders, Specific | Developmental Communication Disorders

United Kingdom
University of East Anglia
PepsiCo Global R&D; Quadram Institute Bioscience

Unknown

Innovation in Food Production Techniques to Improve Bioactive Content (ENRICH)

Bioavailability

United Kingdom

Clinical Trials Sponsored by Aeglea Biotherapeutics

Sponsors and Collaborators

Medical Conditions

Drug Interventions

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CROs in Dominican Republic

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