Clinical Trials Sponsored by Algenis SpA

Total 3120 results

Algenis SpA

Completed

Gonyautoxin 2/3 in the Treatment of Acute Back Pain: A Clinical Proof-of-concept Study

Back Pain | Acute Pain

Chile
Algenis SpA
Covance

Completed

NAVX-010-Phase I Tolerability and Pharmacokinetic Study in Healthy Male Subjects

Safety
Algenis SpA
Oncoclínicas

Recruiting

Proof of Principle Study Evaluating Gonyautoxins NEURO SERUM, on Chemotherapy-induced Peripheral Neuropathy

Chemotherapy-induced Peripheral Neuropathy

Brazil
Cross Research S.A.
Zambon SpA

Completed

Riluzole Orodispersible Film Replicate Bioavailability

Bioequivalence

Switzerland
Zambon SpA
Cross Research S.A.

Completed

Drug Interaction Study of Safinamide and a BCRP Substrate, Diclofenac, Concomitantly Administered to Healthy Volunteers

Healthy

Switzerland
Cross Research S.A.
Zambon SpA

Completed

Safinamide Steady State Interaction With Rosuvastatin

Healthy

Switzerland
Abgenix

Completed

A Blinded Study Comparing the Safety and Efficacy of a Fully Human Anti-IL8 Monoclonal Antibody (ABX-IL8) to Placebo in Patients With Chronic Bronchitis and COPD

Pulmonary Disease, Chronic Obstructive | Bronchitis, Chronic

United States
Abbott
Almedis

Completed

IndoProCaf Effervescent Tablets Effectiveness in Acute Treatment of Migraine and/or Episodic Tension-type Headache and Patients' Satisfaction With the Treatment in Routine Clinical Practice (PRESTO)

Headache Disorders, Primary | Tension-Type Headache | Migraine Without Aura | Migraine With Aura

Kazakhstan, Ukraine
Agenus Inc.

Active, not recruiting

Anti-CD137 and Anti-CTLA-4 Monoclonal Antibody in Patients With Advanced Cancer

Advanced Cancer

United States
Agenus Inc.

Suspended

A Study of Botensilimab (AGEN1181) for the Treatment of Advanced Melanoma

Advanced Melanoma

United States, Spain, United Kingdom, France, Germany, Switzerland, Belgium, Italy, Brazil, Russian Federation
Agenus Inc.

Completed

Subjects With Metastatic or Locally Advanced Solid Tumors, and Expansion Into Select Solid Tumors (Cervical)

Cervical Cancer

United States, Hungary, Spain, Australia, Ukraine, Georgia, Poland, Brazil, Moldova, Republic of
Agenus Inc.

Terminated

Study of AGEN1884 With Pembrolizumab in 1L NSCLC

NSCLC Stage IV

New Zealand, Australia
Agenus Inc.

Terminated

Safety and Tolerability Study of AutoSynVax™ Vaccine in Subjects With Advanced Cancer

Advanced Cancer

United States
Aleris Obesity

Completed

Effects of Long Biliopancreatic Limb vs. Long Alimentary Limb in Superobesity, a Randomized Study

Weight Loss | Morbid Obesity

Sweden
Agenus Inc.

Terminated

Clinical Trial Studying a Personalized Cancer Vaccine in Patients With Non-metastatic Kidney Cancer

Kidney Cancer | Renal Cell Carcinoma

United States, Canada
Agenus Inc.

Completed

Study of the Feasibility to Derive Vaccine From Tumor Tissue in Patients With Non-Small Cell Lung Cancer

Lung Cancer | Non-Small-Cell Lung Carcinoma | Pulmonary Cancer

United Kingdom
Agenus Inc.

Completed

Trial Evaluating Safety, Tolerability and Immune Response of AG-707

Genital Herpes

United States
Alentis Therapeutics AG

Recruiting

Rescue of Nephrons With ALE.F02 (RENAL-F02) (RENAL-F02)

Glomerulonephritis Rapidly Progressive

Czechia, Spain, Germany, Denmark, Italy, United Kingdom, France, Switzerland, Sweden, Turkey
Alentis Therapeutics AG

Recruiting

A Clinical Trial of ALE.F02 in Patients With Advanced Liver Fibrosis and/or With Mild Cirrhosis (FEGATO-01)

Liver Cirrhosis | Advanced Liver Fibrosis

Germany, Romania, Slovakia
R-Pharm
Almedis

Completed

A Drug Interaction Study to Assess the Pharmacokinetics of Narlaprevir and Antiretroviral Drugs

Healthy

Russian Federation
Agenus Inc.

Recruiting

A Study of Botensilimab in Participants With Metastatic Pancreatic Cancer

Metastatic Pancreatic Ductal Adenocarcinoma

United States
Agenus Inc.

Recruiting

Fc-Engineered Anti-CTLA-4 Monoclonal Antibody in Advanced Cancer

Melanoma | Ovarian Cancer | Prostate Cancer | Non-small-cell Lung Cancer | Endometrial Cancer | Advanced Cancer | Angiosarcoma | Fibrolamellar Carcinoma | Colorectal Cancer Without Liver Metastases

United States
Agenus Inc.

Completed

Study of AGEN2034 in Advanced Tumors and Cervical Cancer

Cervical Cancer | Advanced Cancer

France, United States, Belgium, Australia, Spain, Estonia, Brazil, Chile, Poland
Agenus Inc.

Completed

AGEN1884, an Anti-CTLA-4 Human Monoclonal Antibody in Subjects With Advanced or Refractory Cancer and Who Have Progressed With PD-1/PD-L1 Inhibitor as Their Most Recent Therapy

Advanced Solid Cancers | Advanced Solid Cancers Refractory to PD-1

United States
Agenus Inc.

Withdrawn

AGEN2034 & AGEN1884 in Patients With Recurrent, Inoperable Angiosarcoma

Angiosarcoma
Agenus Inc.

Completed

Phase 1a Study to Evaluate Immunogenicity of ASV®

Solid Tumor, Adult

United States
Aleris Helse

Completed

Perioperative Hypothermia Hypothermia in Ambulatory Surgery

Perioperative/Postoperative Complications

Norway
Agenus Inc.

Terminated

Trial to Compare the Routes of Administration of an Investigational, Personalized, Therapeutic Cancer Vaccine Oncophage (HSPPC-96) in Patients With Metastatic Renal Cell Carcinoma

Renal Cell Carcinoma

United States
Agenus Inc.

Completed

Survival Study Of Oncophage® vs. Observation In Patients With Kidney Cancer

Renal Cell Carcinoma

United States, France, Poland, United Kingdom, Spain, Israel, Canada, Belgium, Norway, Sweden, Austria
Agenus Inc.

Completed

Study of Heat Shock Protein-Peptide Complex (HSPPC-96) Versus IL-2/DTIC for Stage IV Melanoma

Malignant Melanoma

United States, Australia, Poland, Ukraine, United Kingdom, Russian Federation, Hungary, Italy, Sweden
Soroka University Medical Center
Lot Spa Hotel Dead Sea

Completed

The Effects of Ambulatory Treatment at the Dead Sea on Osteoarthritis of the Knees

Osteoarthritis of the Knees
Abgenix
Immunex Corporation

Completed

ABX-EGF (a Monoclonal Antibody) Given to Patients With Prostate Cancer With or Without Tumor in Other Parts of the Body

Prostate Cancer

United States
Centervue SpA

Recruiting

Clinical Evaluation of Visual Field Change in Glaucoma: an Assessment of Different Models of Progression

Glaucoma

Italy
MMI Spa

Recruiting

PRIMO Post-Market Clinical Follow Up Study (PRIMO)

Open Surgery | Blood Vessels, Lymphatic Ducts and Nerves | Free Flaps

Spain, Switzerland, Italy, Belgium, Austria, Germany
Labomar SPA

Completed

Study for Evaluation of Probiotics in the Re-equilibration of the Intestinal Microbiota, in Paediatric Age

Diarrhea

Italy
Permedica spa

Completed

Total Knee Arthroplasty With Vitamin E Polyethylene

Knee Osteoarthritis

Italy
Zambon SpA

Active, not recruiting

Efficacy + Safety of Liposome Cyclosporine A to Treat Bronchiolitis Obliterans Post Single Lung Transplant (BOSTON-2) (BOSTON-2)

Bronchiolitis Obliterans | Lung Transplant Rejection | Lung Transplant; Complications | Lung Transplant Failure and Rejection | Chronic Rejection of Lung Transplant | Chronic Lung Allograft Dysfunction

France, United States, Spain, Israel, Belgium, Denmark, Germany, United Kingdom, Austria
SIFI SpA

Completed

Non-comparative Trial Following Participants Implanted Bilaterally With Mini WELL Toric Ready Intraocular Lens for 6 Months After the Second Eye Implant (FUSION) (FUSION)

Astigmatism | Bilateral Cataract

Spain, France, Germany
Zambon SpA

Completed

Phase 1 Three Part SAD, MAD & Cross-Over Study of ZP-059 in Healthy and Asthmatic Subjects

Allergic Bronchopulmonary Aspergillosis

United Kingdom
VISUfarma SpA

Unknown

Evaluate the Improving Effects of Visucomplex Plus on Quality of Life in Patients With AMD

AMD

Italy
Permedica spa

Terminated

Effectiveness of Titanium Niobium Nitride Coating in Total Knee Arthroplasty

Knee Arthritis
VISUfarma SpA

Completed

Evaluation of MAF-1217 in Patients With DED

Evaporative Dry Eye Disease

Italy
VISUfarma SpA

Completed

Evaluation of the VisuXL® Performance on Ocular Surface Discomfort

Ocular Discomfort

Italy
Ingalfarma SpA

Completed

Study of Dentoxol® Mouthrinse for Oral Mucositis

Oral Mucositis

Chile
Zambon SpA

Completed

Efficacy and Tolerability Study of ZP-025 Vaginal Gel for the Treatment of Vaginal Dryness

Vaginal Dryness

Italy
SIFI SpA

Completed

Safety and Tolerability of Preservative-free Polyhexamethylene Biguanide (PHMB) Ophthalmic Solution in Healthy Subjects

Acanthamoeba Keratitis
Permedica spa

Active, not recruiting

Follow-up Evaluating Clinical and Radiological Outcomes of Total Shoulder Arthroplasty With Permedica's MIRAI Prosthesis

Psoriatic Arthritis | Shoulder Osteoarthritis | Primary Osteoarthritis | Secondary Osteoarthritis | Avascular Necrosis of Humerus | Rheumatoid Arthritis Shoulder | Cuff Tear Arthropathy | Fracture, Shoulder

Germany, Italy, Switzerland
Zambon SpA

Terminated

Trial in Non-cystic Fibrosis Bronchiectasis Patients With Chronic Lung Infections Treated With Colistimethate Sodium. (PROMIS-II)

Non Cystic Fibrosis Bronchiectasis

United States, Argentina, Australia, Canada, France, Germany, Greece, Israel, Italy, New Zealand, Poland, Portugal
Zambon SpA

Completed

Efficacy and Safety of Inhaled CMS in Bronchiectasis Subjects With Chronic P. Aeruginosa Infection. (PROMIS-I) (PROMIS-I)

Non Cystic Fibrosis Bronchiectasis

Australia, Greece, Israel, Italy, Portugal, Belgium, Germany, Netherlands, New Zealand, Spain, Switzerland, United Kingdom
Zambon SpA

Active, not recruiting

Efficacy + Safety of Liposome Cyclosporine A to Treat Bronchiolitis Obliterans Post Single Lung Transplant (BOSTON-1) (BOSTON-1)

Bronchiolitis Obliterans | Lung Transplant Rejection | Lung Transplant; Complications | Lung Transplant Failure and Rejection | Chronic Rejection of Lung Transplant | Chronic Lung Allograft Dysfunction

France, United States, Spain, Israel, Belgium, United Kingdom, Germany

Clinical Trials Sponsored by Algenis SpA

Sponsors and Collaborators

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