Clinical Trials Sponsored by Appletree AG

Total 2334 results

University of Zurich
Ixodes GmbH; Appletree AG

Completed

Safety, Skin and Plasma Concentration of Azithromycin Dermal Formulation (IXO-01)

Lyme Disease

Switzerland
Children's National Research Institute
AppleTree Institute; The Maddux School

Enrolling by invitation

Development and Pilot Testing of a Novel Preschool Executive Function Curriculum

Executive Dysfunction

United States
Bottneuro AG
Hemex AG

Active, not recruiting

Evaluate the Safety and Feasibility of tACS With the Miamind Neurostimulator in Healthy Participants (MindStim)

Healthy Participants | Healthy Population

Switzerland
Tetec AG
Aesculap AG

Completed

Non-Interventional Study to Evaluate Safety and Efficacy of NOVOCART 3D in Patients With Cartilage Defects (NISANIK)

Cartilage Diseases

Germany
Santersus AG
ISS AG

Not yet recruiting

Safety, Tolerability and Performance of the NucleoCapture Device in the Reduction of Circulating cfDNA/NETs in Subjects With Sepsis (NUC-CAP)

Sepsis | Respiratory Failure

United Kingdom, Germany, Switzerland
SynDermix AG
ISS AG

Withdrawn

Safety and Efficacy of SDX-3101 for the Treatment of Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP) (SDX-3101)

Chronic Rhinosinusitis Without Nasal Polyps

Germany, Austria, Switzerland
Tetec AG
Aesculap AG

Completed

Observational Study With NOVOCART® Inject in the Reconstruction of the Hip Joint With Full Thickness Cartilage Defects (HIP-ACTION)

Cartilage Disease

Germany
Spiden AG
DCB Research AG

Completed

A Pilot Study to Assess the Feasibility of a Novel Non-invasive Technology to Measure Changing Blood Glucose Levels in Adults With Type-1 Diabetes Mellitus

Type 1 Diabetes Mellitus | Type 1 Diabetes Mellitus With Hypoglycemia | Type 1 Diabetes Mellitus With Hyperglycemia

Switzerland
iOMEDICO AG
Roche Pharma AG

Active, not recruiting

Registry for Molecular Testing, Treatment and Outcome of Patients With Solid Tumors Harboring a NTRK Gene Fusion (REALTRK)

NTRK Family Gene Mutation

Switzerland, Germany
iOMEDICO AG
Roche Pharma AG

Completed

Impact of eHealth Monitoring on Overall Survival in Patients With Metastatic NSCLC / Extensive-stage SCLC / Advanced TNBC Under First-line Treatment With Atezolizumab Plus Chemotherapy (CHAPLIN)

Extensive-stage Small Cell Lung Cancer | Stage IV Non-small Cell Lung Cancer | Advanced (Locally Advanced and Inoperable or Metastatic), PD-L1 IC-positive TNBC

Germany
Swiss Medical Food AG
iOMEDICO AG

Completed

Observational STudy to Evaluate the EFfectiveness of OnLife® in Improving CIPN in Patients With Colon or Breast Cancer After End of Adj. Therapy (STEFANO)

CIPN in Adjuvant Colon Cancer Patients | CIPN in Adjuvant Breast Cancer Patients

Germany
hemotune AG

Not yet recruiting

First in Human Trial to Assess the Safety & Efficacy of HemoSystem REBOOT in Patients With Sepsis-induced Immunosuppression ((RESTORE))

Septic Shock

Switzerland
ARTIDIS AG

Recruiting

ARTIDIS Nanomechanical Generated Measurements for Early Breast Lesions (ANGEL)

Breast Cancer

United States
Medicel AG

Not yet recruiting

Evaluation of Performance of New IFIS Sleeve

Cataract
Lumendo AG

Recruiting

A Study to Compare Various Root Canal Cleaning Devices Based on Cavitation,Ultrasonic and Conventional Methods.

Apical Periodontitis

Turkey
Aesculap AG

Not yet recruiting

Comparative Study of Navigation-assisted OrthoPilot® Elite and Robotic-assisted MAKO® Total Knee Arthroplasty (ORMAK)

Joint Diseases | Osteoarthritis, Knee | Rheumatoid Arthritis of Knee | Posttraumatic Arthropathy

Germany
Pregnolia AG

Recruiting

Mapping the Uterine Cervix Stiffness of Pregnant Women at Mid Gestation (MAPVIX)

Cervix; Pregnancy

Switzerland
Stratpharma AG

Recruiting

StrataXRT Versus Aquaphor for the Prevention and Management of Radiation Dermatitis

Radiation Dermatitis

United States
Aesculap AG

Recruiting

Ceramic Modular Dual Mobility in Primary Total Hip Arthroplasty (THA) (CeMoD-prime)

Coxarthrosis; Primary

Czechia
Biotronik AG
Biotronik AG

Not yet recruiting

Safety and Clinical Performance of the DREAMS 3G Resorbable Magnesium Scaffold System (BIOMAG-II)

Myocardial Ischemia | Coronary Artery Disease | Angina Pectoris | Acute Coronary Syndrome | Ischemic Heart Disease | Atherosclerosis, Coronary
Gaia AG

Recruiting

Effectiveness of an Online Self-management Intervention for Type 2 Diabetes Mellitus (OnSeT-2D)

Type 2 Diabetes

Germany
Carag AG

Not yet recruiting

Sensing Oxygen Saturations Using Abdominal NIRS With an Investigational Realtime Device (Songbird) ((Songbird))

NEC
Lindenhofgruppe AG

Recruiting

Comparison of Standalone Anterior Lumbar Interbody Fusion (ALIF) L5/S1 Performed With Either rhBMP-2 or ViviGen®

Degenerative Disc Disease | Spondylosis | Spondylolisthesis

Switzerland
Immunic AG

Recruiting

Study to Evaluate the Efficacy, Safety and Tolerability of IMU-838 in Patients With Relapsing Multiple Sclerosis (ENSURE-2)

Multiple Sclerosis, Relapsing-Remitting

Turkey, United States, India, United Kingdom, Bosnia and Herzegovina, Estonia, Poland, Romania, Serbia, Ukraine, Armenia, Peru
Biotronik AG

Recruiting

Resorbable Magnesium Scaffolds Registry

Coronary Artery Disease

Germany
iOMEDICO AG

Recruiting

Breast Cancer Registry Platform (OPAL)

Breast Cancer

Germany
VectivBio AG

Completed

Trial to Evaluate Efficacy and Safety of Apraglutide in SBS-IF (STARS)

Short Bowel Syndrome

United States, France, United Kingdom, Israel, Korea, Republic of, Germany, Japan, Taiwan, Sweden, Belgium, Spain, Czechia, Hungary, Norway, Italy, Argentina, Denmark, Poland
Immunic AG

Active, not recruiting

Study to Evaluate Efficacy, Safety, and Tolerability of IMU-838 in Patients With Progressive Multiple Sclerosis (CALLIPER)

Multiple Sclerosis

United States, Germany, Netherlands, Bulgaria, Serbia, Canada, Czechia, Moldova, Republic of, North Macedonia, Poland, Romania, Ukraine
Aesculap AG

Active, not recruiting

Longterm-Evaluation of Vitelene® Against Standard (VITAS)

Arthritis | Osteoarthritis, Hip

Germany
Aesculap AG

Completed

Quintex® Follow-up After One Year Minimum (Quintex)

Trauma | Degenerative Disc Disease | Spinal Stenosis | Cervical Spondylosis | Spondylolisthesis | Deformity of Spine | Instability; Back | Pseudoarthrosis of Spine

Germany
Medela AG

Completed

Initiate Study Evaluating if Mothers Who Are Both Breastfeeding and Pumping in the First Days After Delivery Report Improved Comfort Levels With the New Symphony Program Card (Initiate)

Breast Pumping

Netherlands
MorphoSys AG

Active, not recruiting

Tafasitamab + Lenalidomide + R-CHOP Versus R-CHOP in Newly Diagnosed High-intermediate and High Risk DLBCL Patients (frontMIND)

Diffuse Large B-cell Lymphoma

Germany, France, Hungary, Italy, Spain, United States, Austria, Czechia, Australia, Israel, Korea, Republic of, Turkey, Taiwan, Argentina, Canada, Colombia, Ireland, Japan, Malaysia, New Zealand, Philippines, Poland, Romania, Russian... and more
Aesculap AG

Active, not recruiting

Post Market Clinical Follow-Up of Plasmafit® Cup

Total Hip Arthroplasty

Germany
Aesculap AG

Active, not recruiting

Cemented TrendHip® - Multicenter PMCF Study on Total Indications (TRESTI)

Rheumatoid Arthritis | Hip Dysplasia | Fractures, Hip | Necrosis, Femur Head | Coxarthrosis; Primary | Coxarthrosis; Post-Traumatic

Germany
Nexilis AG

Terminated

Safety and Efficacy of the ISS Sleeve Augmentation Technique in the Treatment of Thoracolumbar Osteopenic Fractures

Osteoporotic Fracture of Vertebra

Austria
Aesculap AG

Completed

PMCF Study on CranioFix®2 System Used for the Fixation of Craniotomized Bone Flaps and Fractures (CRANFLAP)

Skull Fractures

Germany
VectivBio AG

Completed

Relative Bioavailability of a New Presentation of Apraglutide Versus the Reference Formulation

Healthy Subjects

Netherlands
Sonova AG

Active, not recruiting

Lyric4 Outcomes Evaluation

Hearing Loss

United States
Neurimmune AG

Completed

First-in-Human Study of NI006 in Patients With Amyloid Transthyretin Cardiomyopathy

Amyloid Transthyretin Cardiomyopathy

Germany, France, Netherlands, Spain
Spexis AG

Terminated

Pivotal Study in HER2 Negative, Locally Recurrent or Metastatic Breast Cancer (FORTRESS)

Metastatic Breast Cancer | Locally Recurrent Breast Cancer

Spain, Belgium, United States, United Kingdom, Korea, Republic of, Taiwan, Italy, Russian Federation, Czechia, France, Brazil, Argentina, Ukraine
Bitop AG

Active, not recruiting

Multicentre Post-market Study of Ectoin® Inhalation Solution in Treatment of Asthma. (EIL-AST)

Asthma

Poland
Kinarus AG

Suspended

The KIN-FAST Trial (KIN001 For Accelerated Symptoms Termination) in Non Hospitalized Patients Infected With SARS-CoV-2 (KIN-FAST)

COVID-19

Switzerland, Germany
Sonova AG

Completed

Pre-calculation for Frequency Lowering With Hearing Devices

Frequency Lowering

Switzerland
Aesculap AG

Withdrawn

Study Measuring the Effects of Patient Data for Total Hip and Total Knee Arthroplasty Patients Using an APP Based Sensor for Home Exercise Performance Before and After Operation (ORTHOPATH)

Arthroplasty, Replacement, Knee | Patient Satisfaction | Arthroplasty, Replacement, Hip | Clinical Outcome | Treatment Cost

Germany
VectivBio AG

Completed

Metabolic Balance Study of Apraglutide in Patients With SBS-IF and Colon-in-Continuity (STARSnutrition)

Short Bowel Syndrome

Belgium, France
Bitop AG

Completed

Non-Interventional Multicentre Post-market Study of Ectoin® Vaginal Gel for Symptomatic Treatment of Vaginal Atrophy (EIC01-PMCF)

Vaginal Atrophy

Germany
Sonova AG

Completed

Effect of Hearing Aid Labeling on Speech Understanding Measures

Hearing Loss

United States
Sonova AG

Completed

Clinical Performance Evaluation of 3D Ear Canal Scanning Technology

Ear Mold Impression Procedure

United States
Sonova AG

Completed

Hearing Aid Quality and Reliability Study

Hearing Loss

United States
VectivBio AG

Completed

Study of Pharmacokinetics and Safety of Apraglutide in Participants With Normal and Impaired Kidney Function.

Chronic Kidney Disease

United States

Clinical Trials Sponsored by Appletree AG

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