Clinical Trials Sponsored by Applied Molecular Evolution

Total 22 results

Applied Molecular Evolution

Completed

Safety and Efficacy Study of an Anti-CD20 Monoclonal Antibody (AME-133v) to Treat Non-Hodgkin's Lymphoma

Non-Hodgkin's Lymphoma

United States
Applied Molecular Evolution
Eli Lilly and Company

Completed

A Phase 1 Safety Study of LY2127399 in Combination With Bortezomib

Multiple Myeloma

United States
Applied Molecular Transport

Completed

Study of the Safety and Efficacy of AMT-101 in Subjects With Pouchitis (FILLMORE)

Pouchitis

United States, Canada, France, Spain, United Kingdom, Germany, Belgium, Hungary, Netherlands, Switzerland
Applied Molecular Transport

Completed

SAD/MAD Study in Healthy Subjects and Adults With UC to Evaluate Safety, Tolerability, PK, PD of AMT-101 (AURIGA1)

Ulcerative Colitis

Germany, Georgia, Moldova, Republic of, Ukraine
Applied Molecular Transport

Active, not recruiting

Study of the Efficacy and Safety of AMT-101 in Subjects With Ulcerative Colitis (LOMBARD)

Ulcerative Colitis

United States, Hungary, Ukraine, Germany, United Kingdom, Belarus, Bulgaria, Canada, France, Georgia, Moldova, Republic of, Poland, Russian Federation, Switzerland
Applied Molecular Transport

Completed

Study of the Efficacy and Safety of AMT-101 in Combination With Adalimumab in Subjects With Ulcerative Colitis (MARKET)

Ulcerative Colitis

Georgia, Netherlands, Poland, Ukraine
Applied Molecular Transport

Completed

SAD Study to Assess the Safety, Tolerability, PK, and In-Vivo Performance of AMT-126 in Healthy Male and Female Subjects

Healthy Volunteers

United Kingdom
Amsterdam Molecular Therapeutics
International Antiviral Therapy Evaluation Center

Unknown

Safety and Efficacy in LPL-Deficient Subjects of AMT-011, an Adeno-Associated Viral Vector Expressing Human Lipoprotein Lipase [S447X]

Familial Lipoprotein Lipase Deficiency

Canada
Dr. Frank Behrens
Pfizer

Recruiting

Capability of Tofacitinib or Etanercept to Accelerate Tapering of NSAID and Treat-to-target Guided De-escalation of Corticosteroids in RA Patients (AcceleRAte)

Rheumatic Arthritis

Germany
Gerd Geisslinger
Fraunhofer Institute for Molecular Biology and Applied Ecology

Completed

Bioavailability, Pharmacokinetics and Tissue Distribution of R-flurbiprofen Capsules in Healthy Subjects

Healthy Volunteers

Germany
Fraunhofer Institute for Molecular Biology and...
Bristol-Myers Squibb; Goethe University

Completed

PREVALENCE OF Anti-CCP POSITIVITY AND SUBCLINICAL SIGNS OF INFLAMMATION IN PATIENTS WITH NEW ONSET OF NON-SPECIFIC MUSCULOSKELETAL SYMPTOMS (PANORA)

Rheumatoid Arthritis

Germany
Dr. Frank Behrens
SocraMetrics GmbH

Completed

TMP001 in Relapsing-remitting Multiple Sclerosis

Remitting-Relapsing Multiple Sclerosis

Germany
Dr. Frank Behrens
Bionorica SE

Recruiting

Effect of Bronchipret on Antiviral Immune Response in Patients With Mild COVID-19 (BroVID)

COVID-19

Germany
Dr. Frank Behrens
Bionorica SE

Active, not recruiting

Impact of Silymarin Dosages to Decrease Drug-induced Elevated Liver Enzymes Compared to Placebo (SILVER)

Drug-induced Liver Injury

Germany
Dr. Frank Behrens
Janssen-Cilag Ltd.

Completed

Impact of Concomitant MTX on Efficacy, Safety and Adherence of Ustekinumab-treatment in Patients With Active PsA (MUST)

Psoriatic Arthritis

Germany
Thomas More University of Applied Sciences
Revalidatieziekenhuis RevArte; To Walk Again REVAlution Center

Completed

Immersive Care - Virtual Mirror Therapy

Stroke

Belgium
Dr. Frank Behrens
Johann Wolfgang Goethe University Hospital

Recruiting

Prevention of Paclitaxel-induced Neuropathic Pain in Patients With Planned Paclitaxel Chemotherapy (PrevTel) (PrevTel)

Neuropathic Pain | Chemotherapy Effect

Germany
Dr. Frank Behrens
Celgene; Dermatology Department University Hospital Frankfurt

Completed

Preliminary Efficacy and Safety of Apremilast in the Treatment of Acne Conglobata (APACCO)

Acne Conglobata

Germany
Prophylix Pharma AS
Larix A/S; Fraunhofer Institute for Molecular Biology and Applied Ecology; Deutsches... and other collaborators

Completed

Kinetics of Blood Platelets Transfused to Healthy Subjects

Fetal and Neonatal Alloimmune Thrombocytopenia

Germany
Dr. Frank Behrens
University Hospital Frankfurt, Department of Anaesthesiology; IRON4U; University...

Recruiting

Postoperative i.v. Iron Substitution in Patients With Diagnosed Iron Deficiency (IDA-II)

Iron Deficiency Anemia

Germany
Dr. Frank Behrens
University Hospital Frankfurt, Department of Anaesthesiology; IRON4U; University...

Suspended

Polyglucoferron Compared to i.v. Ferric Carboxymaltose and Oral Iron Substitution in Preoperative Treatment of Iron Deficiency Anaemia in Patients (IDA-I)

Iron Deficiency Anemia

Germany
R-Evolution Worldwide S.r.l. Impresa Sociale
University Ghent; National Institute for Medical Research, Tanzania; University... and other collaborators

Not yet recruiting

Assessment of Combined Praziquantel and Albendazole vs Albendazole Alone to Treat Active Parenchymal Neurocysticercosis (NeuroSolve)

Neurocysticercosis

Clinical Trials Sponsored by Applied Molecular Evolution

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