Clinical Trials Sponsored by Army Research Laboratory

Total 646 results

U.S. Army Medical Research and Development Command
Naval Medical Research Center

Withdrawn

A Clinical Trial to Evaluate Plasmodium Falciparum 7G8 and NF54 Challenge Strains (PfSPZ) in a Head-to-head Comparative Study - (ECG-CHMI) (ECG-CHMI)

Plasmodium Falciparum
Huntington Medical Research Institutes
U.S. Army Medical Research and Development Command

Completed

Multimodal Approach to Testing the Acute Effects of Mild Traumatic Brain Injury (mTBI)

Concussion, Mild

United States
Evidation Health
Defense Advanced Research Projects Agency; Army Research Office (ARO)

Unknown

Promoting Flu Vaccination Through a Mobile Wellness Program

Not Condition-specific

United States
Naval Health Research Center
U.S. Army Medical Research and Development Command

Completed

Effectiveness of the Pneumococcal Polysaccharide Vaccine in Military Recruits

Pneumonia | Acute Respiratory Disease

United States
U.S. Army Medical Research and Development Command
Walter Reed Army Medical Center; Ohio State University

Unknown

Questionnaire Study for Gynecological Cancer Survivors

Uterine Cervical Neoplasms | Genital Neoplasms, Female | Ovarian Neoplasms | Endometrial Neoplasms | Vulvar Neoplasms | Vaginal Neoplasms

United States
Massachusetts General Hospital
Walter Reed Army Medical Center; U.S. Army Medical Research and Development...

Completed

Internet-Based Cervical Cytology Screening Program (IBCCSP)

Cervical Cancer

United States
U.S. Army Medical Research and Development Command
United States Department of Defense; Walter Reed Army Institute of Research...

Completed

Clinical Trial for the Development of a Safe Malaria Challenge Model That Can be Reproduced in Humans (Pvivax)

Plasmodium Vivax Malaria

United States
Universita degli Studi di Catania
Laboratory for Health Protection Research

Completed

Pharmacokinetic Profile of Toxic Substances and Nicotine in Electronic Cigarettes (KINECIG)

Tobacco Abuse Smoke

Italy
U.S. Army Medical Research and Development Command
Walter Reed Army Institute of Research (WRAIR); Walter Reed National Military...

Terminated

Safety, Efficacy, and PK of Topical Paromomycin/Gentamicin Cream for Treatment of Cutaneous Leishmaniasis (WRNMMC)

Leishmaniasis, Cutaneous

United States
Changping Laboratory
Henan Provincial People's Hospital; China Rehabilitation Research Center

Recruiting

Precision TMS Treatment Guided by Personalized Brain Functional Sectors (pBFS) for ASD

Autism Spectrum Disorder

China
University of Arizona
U.S. Army Medical Research Acquisition Activity

Recruiting

Effect of Morning Light Exposure on Mood (BLM)

Suicidal Ideation | Regulation, Emotion

United States
Tissue Genesis
U.S. Army Medical Research and Development Command

Active, not recruiting

Evaluation of the Tissue Genesis® Icellator Cell Isolation System™ to Treat Critical Limb Ischemia (CLI-DI)

Critical Limb Ischemia

United States
U.S. Army Medical Research and Development Command
SmithKline Beecham

Completed

An Evaluation of Weekly Tafenoquine

Falciparum Parasitaemia
U.S. Army Medical Research and Development Command
Institut Pasteur

Completed

Cosmetic Outcome of Leishmaniasis Scar After WR279396 Application (SCAR)

Scar | Cutaneous Leishmaniasis

Tunisia
HamesNet Research Network
Pearl Network; Eisenhower Army Medical Center

Unknown

Eisenhower's Alternative Speculum Examination (EASE)

Papanicolaou Smear

United States
U.S. Army Medical Research and Development Command
GlaxoSmithKline; Walter Reed Army Institute of Research (WRAIR); The PATH Malaria...

Completed

Phase I/II Trial of a Malaria Vaccine in Adults Living in the United States of America

Malaria | Plasmodium Falciparum Malaria

United States
University of Arizona
U.S. Army Medical Research Acquisition Activity

Completed

Bright Light Therapy for Treatment of Sleep Problems Following Mild Traumatic Brain Injury

Concussion, Mild | Sleep Problems | Post-Concussion Symptoms

United States
Georgetown University
U.S. Army Medical Research and Development Command

Completed

Exercise in Gulf War Illness (GWI)

Persian Gulf Syndrome | Gulf War Illness

United States
Neumedicines Inc.
U.S. Army Medical Research and Development Command

Completed

NM-IL-12 (rHuIL-12) in Subjects With Open Surgical Wounds

Colostomy Stoma

United States
U.S. Army Medical Research and Development Command
SmithKline Beecham

Completed

Evaluation of Weekly Tafenoquine

Malaria
Georgetown University
U.S. Army Medical Research and Development Command

Completed

Study of Gulf War Illness (GWI) by Comparing GWI and Healthy Veterans

Gulf War Illness | Persian Gulf War Syndrome

United States
University of Arizona
U.S. Army Medical Research Acquisition Activity

Completed

Effects of Bright Light Therapy in Mild Traumatic Brain Injury

Concussion, Mild | Sleep Problems | Post-Concussion Symptoms

United States
U.S. Army Medical Research Acquisition Activity
The Geneva Foundation

Unknown

Reduced Planning Target Volume (PTV) Margins for the Treatment of Prostate Cancer Using the Calypso 4D Localization System (PTV)

Prostate Cancer

United States
U.S. Army Medical Research Acquisition Activity
The Geneva Foundation

Unknown

External Immobilization Compared to Limited Immobilization Using a Novel Real-time Localization System of the Prostate

Prostate Cancer

United States
HealthPartners Institute
U.S. Army Medical Research and Development Command

Completed

Predictors of Lymphedema Following Breast Cancer Surgery

Breast Cancer | Lymphedema

United States
Georgetown University
U.S. Army Medical Research and Development Command

Completed

Treatment Decision Making in Early-Stage Prostate Cancer

Localized Prostate Cancer

United States
University of Florida
U.S. Army Medical Research Acquisition Activity

Recruiting

BioFLO for Respiratory Recovery in SCI

Spinal Cord Injuries

United States
Walter Reed Army Institute of Research (WRAIR)
Philips Healthcare

Recruiting

Acoustic Stimulation During Restricted Sleep After Sleep Deprivation

Performance | Sleep Deprivation | Sleep Restriction | Alertness | Acoustic Stimulation

United States
Emergent BioSolutions
Walter Reed Army Institute of Research (WRAIR)

Terminated

A Study to Assess the Safety, Pharmacodynamics, and Immunogenicity of PXVX0047

Adenoviral Infection

United States
University of Arizona
U.S. Army Medical Research Acquisition Activity

Completed

A Non-Pharmacological Method for Enhancing Sleep in PTSD

PTSD | Sleep Problems

United States
U.S. Army Medical Research and Development Command
SIGA Technologies

Available

Tecovirimat Intravenous Treatment for Orthopox Virus Exposure (TPOXX IV)

Orthopox Virus Infection
Keller Army Community Hospital
Telemedicine & Advanced Technology Research Center

Unknown

Gait Retraining Enhances Athletes' Technique (GREAT)

Knee Osteoarthritis | Anterior Cruciate Ligament Injury

United States
U.S. Army Medical Research and Development Command
SmithKline Beecham

Completed

A Randomized, Double-blind, Placebo-controlled Evaluation of Increasing Doses of Weekly Tafenoquine for Chemosuppression of Plasmodium Falciparum

Malaria
Terumo BCTbio
U.S. Army Medical Research and Development Command

Completed

Inactivation of Whole Blood With Mirasol (IMPROVEII)

Focus of Study: Radiolabel Recovery and Survival of RBCs

United States
Clinical Exercise Physiology and Rehabilitation...
KAT General Hospital

Recruiting

Reliability and Validity of the IASP Clinical Criteria for Identifying Patients With Nociplastic Pain

Chronic Pain | Central Sensitisation | Nociplastic Pain

Greece
Clinical Exercise Physiology and Rehabilitation...
University of Thessaly

Completed

Quarantine and Telerehabilitation in Chronic Pain Patients During COVID-19 Pandemic.

Chronic Pain

Greece
Clinical Exercise Physiology and Rehabilitation...
KAT General Hospital

Completed

Central Sensitization Symptoms and Psychosocial Factors in Athletes After ACL Reconstruction

Anterior Cruciate Ligament Rupture

Greece
Hoffmann-La Roche
PPD; Laboratory Corporation of America; Illingworth Research Group

Active, not recruiting

A Study Evaluating B Cell Levels In Infants Of Lactating Women With CIS Or MS Receiving Ocrelizumab (SOPRANINO)

Multiple Sclerosis | Clinically Isolated Syndrome

United States, Spain, United Kingdom, Germany
PATH
Walter Reed Army Institute of Research (WRAIR); Kenya Medical Research Institute

Completed

Evaluation of the MBio Combined Syphilis/HIV Point-of-Care Diagnostic Test (MBIO)

HIV | Syphilis

Kenya
PATH
Walter Reed Army Institute of Research (WRAIR); Kenya Medical Research Institute

Completed

Clinical Investigation Study to Evaluate the Consistency and Reproducibility of Two Consecutive Mosquito Feeding Assays

Malaria

Kenya
Humacyte, Inc.
U.S. Army Medical Research and Development Command; Atlantic Research Group

Active, not recruiting

Humacyte Human Acellular Vessel (HAV) in Patients With Vascular Trauma

Trauma | Vascular System Injury

United States, Israel
U.S. Army Medical Research and Development Command
United States Agency for International Development (USAID); Walter Reed Army...

Completed

Clinical Trial for Malaria Vaccines to Test for Safety, Immune Response and Protection Against Malaria (DNA-Ad)

Malaria

United States
U.S. Army Medical Research and Development Command
GlaxoSmithKline; Walter Reed Army Institute of Research (WRAIR); The PATH Malaria...

Completed

Phase I/II Trial of a Malaria Vaccine in Adults Living in the United States of America

Plasmodium Falciparum Malaria

United States
PATH
GlaxoSmithKline; Kenya Medical Research Institute; US Army Medical Research Directorate-Africa... and other collaborators

Completed

RTS,S/AS01E Hypo-immuno-responsiveness Study

Plasmodium Falciparum

Kenya
United States Army Research Institute of Environmental...
Massachusetts Institute of Technology; United States Army Natick Soldier Research...

Completed

Brain Energy and Cognition

Sleep Deprivation | Energy Restriction

United States
Hoffmann-La Roche
PPD; Laboratory Corporation of America; Illingworth Research Group

Active, not recruiting

A Study Evaluating B Cell Levels In Infants Potentially Exposed To Ocrelizumab During Pregnancy (MINORE)

Multiple Sclerosis | Clinically Isolated Syndrome

United States, Spain, Switzerland, France, Germany
Feinstein Institute for Medical Research
Cold Spring Harbor Laboratory

Completed

Dornase Alfa Administered to Patients With COVID-19 (DACOVID) (DACOVID)

COVID-19 | Mechanical Ventilation

United States
American Burn Association
U.S. Army Medical Research and Development Command

Completed

A Trial of Restrictive Versus Traditional Blood Transfusion Practices in Burn Patients

Burn Injury

United States, Canada, New Zealand
Banyan Biomarkers, Inc
U.S. Army Medical Research and Development Command

Terminated

Fresh Intravenous Blood Samples for TBI Diagnostic Assay Development With Philips Point of Care System (FIRST DOWN)

Traumatic Brain Injury

Netherlands
Ohio State University
U.S. Army Medical Research and Development Command

Completed

The Head Injury-associated Photosensitivity and Pupillary Function (HIPP) Study (HIPP)

Head Injury | Photophobia | Photosensitivity | Traumatic Brain Injury (TBI)

United States

Clinical Trials Sponsored by Army Research Laboratory

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