- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00391664
Questionnaire Study for Gynecological Cancer Survivors
Gynecologic Cancer Survivorship Survey
Study Overview
Status
Conditions
Intervention / Treatment
Detailed Description
Since the early 1970s, death rates for the major gynecological tumors have significantly declined, with a reduction of 42% for endometrial, 49% for cervix, 27% for vagina and vulva, and 11% for ovarian cancer. Thus, of the approximately 82,000 new gynecologic cases each year, more women will be living and, necessarily be forced to cope with psychological or behavioral morbidity. Psychosocial data on cancer patients portray significant fear and anxiety with diagnosis and treatments and the potential for high levels of psychological and sexual morbidity. While many studies have been done investigating sexual outcomes, little data is available on basic domains of quality of life, i.e. emotional or social adjustment, occupational outcomes, or aspects of physical health that might influence quality of life for gynecologic cancer survivors. There is a need for basic descriptive research in these areas, particularly in investigations that include representative samples from differing socioeconomic and racial/ethnic groups.
The goal of the proposed study is to evaluate quality of life in long-term gynecologic cancer survivors. The specific aims are to:
- Describe quality of life (both mental health and physical functioning components), stress, and sexual functioning among survivors of gynecologic malignancies and
- Describe differences between disease site groups (i.e. cervical, endometrial, ovarian, and vulva).
It has been shown with other cancer groups that improvements in mood and coping can be achieved with brief, cost effective interventions (e.g. ten therapy hours with delivery in a group format). These are multi-modal interventions with stress reduction, disease/treatment information, cognitive behavioral coping strategies, and social support. There is suggestive evidence that disease specific interventions, such as including sexual therapies for gynecologic patients, can result in improvements as well. Research focus on these issues is aided by the availability of reliable and valid strategies to assess both quality of life (SF-36; FACT) and sexuality. Before clinical trials are undertaken, research must provide a comprehensive assessment of quality of life for gynecologic cancer survivors.
Study Type
Enrollment (Anticipated)
Contacts and Locations
Study Locations
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District of Columbia
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Washington, District of Columbia, United States, 20307
- Recruiting
- Walter Reed Army Medical Center
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Contact:
- Karen Livornese, BSN, RN
- Phone Number: 202-782-6244
- Email: karen.Livornese@amedd.army.mil
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Contact:
- Cynthia A Perry, CIP
- Phone Number: (202) 782-8461
- Email: cynthia.perry@amedd.army.mil
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Principal Investigator:
- LTC G. Larry Maxwell, MD
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Ohio
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Columbus, Ohio, United States, 43210
- Active, not recruiting
- Ohio State University
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Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Description
Inclusion Criteria:
- Female participants diagnosed with gynecologic cancer
- Participants between the ages of 20 and 75 years old, inclusive
- Participants previously treated for all stages (I-IV) of the following cancers: cervix; endometrium; ovary; vulva; vagina; and other genital cancers
- Participants receiving treatment for their primary cancer in the past 2-10 years
Exclusion Criteria:
- Male participants
- Participants with major psychoses (e.g. organic brain syndrome; schizophrenia; bipolar disorder; or mental retardation).
- Participants with significant hearing deficit
- Participants with prior non-gynecologic cancer diagnosis
- Participants who refused all forms of cancer treatment, whether standard of care or experimental.
- Participants with deficient ability to read/speak English
- Participants residing >90 miles from the research site
- Participants diagnosed with dementia
- Participants diagnosed with pregnancy
Study Plan
How is the study designed?
Design Details
Collaborators and Investigators
Investigators
- Principal Investigator: LTC G. Larry Maxwell, MD, Walter Reed Army Medical Center
- Study Director: Barbara L Andersen, PhD, Ohio State University
Study record dates
Study Major Dates
Study Start
Study Completion
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Estimate)
Study Record Updates
Last Update Posted (Estimate)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
- Urogenital Neoplasms
- Neoplasms by Site
- Uterine Neoplasms
- Uterine Cervical Diseases
- Uterine Diseases
- Endocrine System Diseases
- Ovarian Diseases
- Adnexal Diseases
- Gonadal Disorders
- Endocrine Gland Neoplasms
- Vaginal Diseases
- Vulvar Diseases
- Neoplasms
- Uterine Cervical Neoplasms
- Ovarian Neoplasms
- Endometrial Neoplasms
- Vulvar Neoplasms
- Genital Neoplasms, Female
- Vaginal Neoplasms
Other Study ID Numbers
- 05-44025
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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