Clinical Trials Sponsored by Astel Medica

Total 56556 results

Astel Medica

Completed

First Line Dose-efficacy Study of Bactecal® D Liquid for Infant Colic (BACTECOLIC)

Colic

Belgium
Astes

Completed

Derivation and Validation of a Combination of BOSTON Score and DES-OSA Score for Selection of OSA Patients.

Obstructive Sleep Apnea

Belgium
Astes

Completed

Influence of Different Parameters on Extubation Time After Cardiac Surgery.

Thoracic Surgery

Belgium
Astes

Completed

Inter Scorers Agreement for OSA Screening Scores.

Sleep Apnea, Obstructive

Belgium
Astes

Completed

Influence of Resident's Degree of Formation on the Quality of Care Delivered to the Patients.

Anesthesia Complication

Belgium
Astes

Completed

Comparison of Oral Zaldiar With Intravenous Paracetamol and Tramadol

Pain
Astes

Completed

Comparison of Delta Pulse Pressure and Delta Down Before and After Sternotomy

Hemodynamics

Belgium
Astes

Withdrawn

Interest of the OSA (Obstructive Sleep Apnea) Predictive Scores in the Prognosis of Postoperative Mortality of Femoral Neck Fractures

Femoral Neck Fracture

Belgium
Astes

Completed

Comparison of Three Methods of Anesthesia to Achieve a Nerve Block Anesthesia.

Anesthesia

Belgium
Astes

Withdrawn

Influence of Extracorporeal Circulation on the Development of OSA (Obstructive Sleep Apnea)

Coronary Artery Disease
Astes

Completed

Influence of Tobacco Smoking on the Development of Obstructive Sleep Apnea (OSA)

Obstructive Sleep Apnea | Tobacco Use
Astes

Completed

Comparison of the New Algorithm of STOP-Bang in the Detection of Severe OSA Patients

Apnea, Sleep

Belgium
Astes

Completed

Comparison of STOP-BANG and DES-OSA as Predictive Score for Difficult Intubation.

Bariatric Surgery Candidate

Belgium
Astes

Completed

Impact of Smoking, Benzodiazepine (BZD) Use and Obesity on Severe Obstructive Sleep Apnea (sOSA)

Smoking | Obesity | Obstructive Sleep Apnea
Astes

Completed

Clinical Use of Prilocaine Chlorhydrate Among a General Surgical Population

Anesthesia

Belgium
Astes

Completed

Adherence to Continuous Positive Airway Pressure Among Obstructive Sleep Apnoea Patients.

Sleep Apnea, Obstructive

Belgium
Astes

Not yet recruiting

Comparison of Methodology Proposed by the SFAR for the Detection by Videoconference of Obstructive Sleep Apnea.

Obstructive Sleep Apnea
Astes

Completed

Comparison of Demographic Data Mentioned by the Patients or Measured by a Physician

Obstructive Sleep Apnea

Belgium
Astes

Completed

Comparison of Two Dosages of Heparin Before Extracorporeal Circulation

Extracorporeal Circulation; Complications

Belgium
Astes

Withdrawn

Determination of Optimal Cutoff Value for Screening Severe Hypoxemic OSA (Obstructive Sleep Apnea) Patients

Sleep Apnea, Obstructive

Belgium
Astes

Completed

Influence of Different Methods of Measurement in the Accuracy of DES-OSA and P-SAP Scores

Sleep Apnea, Obstructive

Belgium
Astes

Completed

Comparison of Preoperative Screening Score for Obstructive Sleep Apnea (OSA)

Sleep Apnea, Obstructive

Belgium
Astes

Withdrawn

Practice Survey on Femoral Neck Fractures and the Incidence of Type of Anesthesia on Patient Outcome

Femoral Neck Fractures

Belgium
Astes

Completed

Comparision of the Use in Marcaine and Chloroprocaine in Rachianesthesia for the Surgical Correction of Inguinal Hernia.

Pain

Belgium
Asten Sante

Recruiting

Consequences of Respiratory Devices on Caregivers (CAP2) (CAP2)

Quality of Life

France
Astex Pharmaceuticals, Inc.

Recruiting

Study to Evaluate the Pharmacokinetics and Safety of Oral Decitabine and Cedazuridine in Cancer Patients With Hepatic Impairment

Acute Myeloid Leukemia | Myelodysplastic Syndromes

Spain, Poland, Bulgaria, Lithuania, Slovakia, Romania
Astex Pharmaceuticals, Inc.

Recruiting

Study to Evaluate the Pharmacokinetics and Safety of Oral Decitabine and Cedazuridine in Cancer Patients With Renal Impairment

Acute Myeloid Leukemia | Myelodysplastic Syndromes

Spain, Poland, Bulgaria, Lithuania, Slovakia, Romania
Astex Pharmaceuticals, Inc.

Active, not recruiting

A Study of TAS1440 With ATRA in Subjects With r/r AML

Acute Myeloid Leukemia

United States
Astex Pharmaceuticals, Inc.

Active, not recruiting

Study of ASTX295 in Patients With Solid Tumors With Wild-Type p53

Solid Tumor

United States
Astex Pharmaceuticals, Inc.

Completed

Guadecitabine (SGI-110) vs Treatment Choice in Adults With MDS or CMML Previously Treated With HMAs

Myelodysplastic Syndromes | Leukemia, Myelomonocytic, Chronic

United States, Spain, Korea, Republic of, France, Denmark, Canada, Germany, Italy, Czechia, United Kingdom, Poland, Japan, Sweden, Belgium
Astex Pharmaceuticals, Inc.

Terminated

Guadecitabine Extension Study

Acute Myeloid Leukemia | Myeloid Dysplastic Syndrome

United States, Taiwan, Korea, Republic of, Canada, Spain, Japan, Italy, Austria, Denmark
Astex Pharmaceuticals, Inc.

Terminated

A Study of ASTX660 as a Single Agent and in Combination With ASTX727 in Subjects With Relapsed/Refractory Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia

United States
Astex Pharmaceuticals, Inc.

Completed

Safety Study to Determine the Maximum Tolerated Dose, Pharmacokinetics and Pharmacodynamics of Oral MP470, a Multitargeted Tyrosine Kinase Inhibitor, in Patients With Solid Malignancies

Solid Tumors

United States
Astex Pharmaceuticals, Inc.

Completed

A Study of HSP90 Inhibitor AT13387 Alone or in Combination With Abiraterone Acetate

Prostate Cancer

United States, United Kingdom, Spain, Canada
Astex Pharmaceuticals, Inc.

Terminated

Orathecin + Gemcitabine Versus Placebo + Gemcitabine in Chemonaive Non-Resectable Pancreatic Cancer

Pancreatic Cancer

United States
Astex Pharmaceuticals, Inc.

Completed

Phase II Trial of Decitabine in Patients With Chronic Myelogenous Leukemia Chronic Phase Who Are Refractory to Imatinib Mesylate (Gleevec)

Chronic Myelogenous Leukemia

United States, Canada
Askel Healthcare Ltd

Recruiting

COPLA® Cartilage Implant Pilot Clinical Trial

Cartilage or Osteochondral Defects in the Knee

Estonia, Finland, Sweden
Astex Pharmaceuticals, Inc.

Active, not recruiting

Study of ASTX029 in Subjects With Advanced Solid Tumors

Solid Tumor, Adult

United States, Spain, France, United Kingdom
Astex Pharmaceuticals, Inc.

Active, not recruiting

Pharmacokinetics, Safety, and Efficacy of ASTX727 in Combination With Venetoclax in Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia

United States, Spain, Canada
Astex Pharmaceuticals, Inc.

Active, not recruiting

Phase 1-2 Study of ASTX660 in Subjects With Advanced Solid Tumors and Lymphomas

Lymphoma | Solid Tumors

United States, Belgium, Spain, Hungary, Italy, Canada, United Kingdom, France
Astex Pharmaceuticals, Inc.

Enrolling by invitation

A Study for Participants Who Participated in Prior Clinical Studies of ASTX727 (Standard Dose), With a Food Effect Substudy at Select Study Centers

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Chronic Myelomonocytic Leukemia

United States, Spain, Canada, Austria, Slovakia, Bulgaria, Hungary
Astex Pharmaceuticals, Inc.

Completed

Study of ASTX727 vs IV Decitabine in MDS, CMML, and AML

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Chronic Myelomonocytic Leukemia

United States, Canada, Spain, Hungary, Austria, Czechia, France, Germany, Italy, United Kingdom
Astex Pharmaceuticals, Inc.

Completed

Phase 3 Randomized, Open-Label Study of Guadecitabine vs Treatment Choice in Previously Treated Acute Myeloid Leukemia

Acute Myeloid Leukemia

United States, Canada, Belgium, Spain, Germany, Denmark, Korea, Republic of, Hungary, France, Japan, Italy, Poland, Sweden, Ukraine, United Kingdom
Astex Pharmaceuticals, Inc.

Completed

Thorough QT Assessment of Cedazuridine in Healthy Subjects

Healthy Volunteers

Netherlands
Astex Pharmaceuticals, Inc.

Completed

SGI-110 in Adults With Untreated Acute Myeloid Leukemia (AML), Not Considered Candidates for Intensive Remission Induction

Leukemia, Myeloid, Acute

United States, Spain, Korea, Republic of, Taiwan, Australia, Canada, Denmark, Hungary, Japan, Finland, Italy, Serbia, Czechia, France, Germany, Sweden, Netherlands, Poland, Russian Federation, Austria, United Kingdom, Romania, Belgium, Bulgar...
Astex Pharmaceuticals, Inc.

Terminated

Dose-finding Study Using Pentostatin for Injection in the Treatment of Steroid-refractory aGvHD

Acute Graft Versus Host Disease

United States
Astex Pharmaceuticals, Inc.

Completed

Effect of Food on the Pharmacokinetics of ASTX660 in Healthy Volunteers

Healthy Volunteer

United States
Astex Pharmaceuticals, Inc.

Completed

A Study to Investigate the Effect of CYP3A4 Inhibition on the Single Dose Pharmacokinetics of ASTX660 and the Effect of a Single Dose of ASTX660 on the Pharmacokinetics of the CYP3A4 Substrate Midazolam

Healthy Volunteer

United States
Astex Pharmaceuticals, Inc.

Completed

Effect of Food on Blood Levels of ASTX727

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Chronic Myelomonocytic Leukemia

United States
Astex Pharmaceuticals, Inc.

Completed

A Study to Investigate the Safety and Efficacy of AT13387, Alone or in Combination With Imatinib, in Patients With GIST

Gastrointestinal Stromal Tumor (GIST)

United States

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