Clinical Trials Sponsored by BRAHMS Biomarkers

Total 106 results

ThermoFisher Scientific Brahms Biomarkers France

Completed

Biomarkers Correlation With Volemia (ENVOL)

Renal Insufficiency | Cerebral Hemorrhage | Head Injury | Non Traumatic Post Surgery | Poly Trauma Patients Without Heart Failure

France
ThermoFisher Scientific Brahms Biomarkers France

Completed

BIOmarkers of Dyspnea IN Emergency Room (BIODINER)

Pulmonary Embolism | Acute Heart Failure | Severe Dyspnea | CAPD | AE COPD

France
Cedars-Sinai Medical Center
ThermoFisher Scientific Brahms Biomarkers France

Completed

Preeclampsia Risk Assessment: Evaluation of Cut-offs to Improve Stratification (PRAECIS)

Gestational Hypertension | Preeclampsia Severe | Preeclampsia and Eclampsia | Chronic Hypertension in Obstetric Context | Superimposed Pre-Eclampsia | Preeclampsia Mild

United States
University of Zurich
ThermoFisher Scientific Brahms Biomarkers France

Completed

MR-proADM and CT-proET-1 During ICU Treatment (MR-proADM)

Acute Phase Biomarkers | Medical ICU Admitted Patients

Switzerland
ThermoFisher Scientific Brahms Biomarkers France
Assistance Publique - Hôpitaux de Paris

Completed

Prognosis Value of Pro-adrenomedullin in Acute Exacerbations of COPD in ER (UTAPE BPCO)

Pulmonary Disease, Chronic Obstructive Patients Admitted in Emergency Department for Acute Exacerbation

France
Brahms AG

Recruiting

Risk Stratification Using Midregional Proadrenomedullin in the ED

Patients Presenting With Suspicion of Infection to the ED

United Kingdom, Spain, Italy, France
Brahms AG

Completed

Chromogranin A as Blood Marker in Cancer Patients

Colorectal Neoplasms | Pancreatic Neoplasms | Gastric Neoplasms | Small Intestinal Neoplasms

United States, Germany
Brahms AG

Completed

Identifying Patients With Suspicion of Infection in the ED Who Have Low Disease Severity Using MR-proADM - Pilot Study (IDEAL)

Patients Presenting With Suspicion of Infection to the ED

Spain
Brahms AG

Terminated

Procalcitonin Level to Discontinue Antibiotics on ICU Patients With no Obvious Site of Infection

Sepsis | Infection | Bacterial Infection

United States
Brahms AG

Completed

Investigation of the Biomarker Copeptin in Patients With Acute Myocardial Infarction (CHOPIN)

Acute Coronary Syndromes

United States
Nantes University Hospital
Roche Pharma AG; BioMérieux; ThermoFisher Scientific Brahms Biomarkers France; ...

Recruiting

Development of an Innovative Clinico-biological Score for the Early Detection of Acute Renal Failure Associated With Cardiac Surgery. (DETECT-AKI)

Acute Kidney Injury

France
Brahms AG

Terminated

Improve Management of Heart Failure With Procalcitonin (IMPACT-EU)

Heart Failure | Infection

Spain, Denmark, Germany, Netherlands
Brahms AG

Completed

Procalcitonin Monitoring Sepsis Study (MOSES)

Septic Shock | Severe Sepsis

United States
Brahms France

Terminated

Study of Procalcitonin (PCT)-Guided Antibiotic Use in Severe Sepsis Patients Without Obvious Infection (Pro-SEPS)

Severe Sepsis

France
Brahms AG

Completed

Biomarkers in Acute Heart Failure (BACH)

Heart Failure | Shortness of Breath

United States, Poland, Switzerland, New Zealand, Germany, Greece, Italy, United Kingdom
Menarini Biomarkers Singapore

Recruiting

Fetal Cell Analysis From Maternal Blood

Pregnancy Related | Genetic Disease | Prenatal Screening

Italy
Banyan Biomarkers, Inc

Completed

Evaluation of Mild TBI in Collegiate Athletes (AWARE)

Traumatic Brain Injury

United States
Saliva Biomarkers, Inc.

Unknown

Comparison of Salivary and Serum Free Testosterone in Normal and Hypogonadal Men

Known Androgen Deficiency

United States
Banyan Biomarkers, Inc

Completed

Biomarkers of Mild and Moderate Traumatic Brain Injury

Brain Injuries, Traumatic

United States, Hungary
Banyan Biomarkers, Inc

Completed

Brain Injury Biomarkers in the General Population

Brain Injuries, Traumatic

United States
Banyan Biomarkers, Inc

Completed

A Evaluation Of Biomarkers Associated With Sports Induced Concussions In College Student Athletes (GATOR)

Traumatic Brain Injury | Sports Injury | Sports Concussion

United States
Banyan Biomarkers, Inc

Terminated

Biomarkers of Brain Injury: Magnitude and Outcome of Mild and Moderate TBI

Brain Injuries, Traumatic

United States
University of Aarhus
Aarhus University Hospital; Regionshospitalet Hammel Neurocenter; Roche Diagnostics and other collaborators

Completed

Neurological Prognostication of Patients in Therapeutic Hypothermia After Cardiac Arrest

Cardiac Arrest

Denmark, Norway
University of Zurich
Brahms AG

Completed

ICG- Liver Test Versus New Biomarkers as Prognostic Markers in Critically Ill Patients (Greenpep)

Critically Ill

Switzerland
Cognizance Biomarkers, LLC
University of Pennsylvania

Completed

Proof of Principle for a Diagnostic Blood Test of Recurrent Seizures

Epilepsy

United States
Kompetenznetz Sepsis
Biosyn; Brahms AG

Completed

Placebo Controlled Trial of Sodium Selenite and Procalcitonin Guided Antimicrobial Therapy in Severe Sepsis (SISPCT)

Septic Shock | Severe Sepsis

Germany
University Hospital, Clermont-Ferrand
Association des Médecins des Urgences de Clermont-Ferrand; BRAHMS Biomarkers; General Hospital Henri Mondor, Aurillac, France

Completed

Copeptin and Acute Coronary Syndrome Without ST-segment Elevation

Chest Pain

France
Charite University, Berlin, Germany
Brahms AG

Completed

Impact of Therapy Optimization on the Level of Biomarkers in Patients With Decompensated Heart Failure (MOLITOR)

Decompensated Heart Failure

Germany
Hospital Centre Biel/Bienne
Brahms AG

Completed

Assessment of Circulating Copeptin Levels in Healthy Subjects and Patients With Renal Insufficiency After Oral Water Load and Hypertonic Saline Infusion

Renal Failure | Hypoosmolality | Hyperosmolality

Switzerland
Heart Failure Biomarker Group

Completed

A Health Economic Evaluation of Using N-Terminal Pro Brain Natriuretic Peptide (NT-Pro BNP) in Acute Heart Failure

Heart Failure

Indonesia
CytoSorbents Europe GmbH
BRAHMS GmbH; MedInnovation GmbH

Recruiting

A RCT to Assess the Performance of CytoSorb for Shock Reversal in Patients With Vasoplegic Septic Shock (PROCYSS)

Septic Shock

Germany
ARNA Genomics US Inc.
BIOMARKER-RU

Recruiting

Retrospective Comparative in Vitro Case-controlled Study of the Liquid Biopsy Test System in Women With Breast Cancer

Breast Neoplasm Female

Russian Federation
Imperial Brands PLC

Completed

A Randomised, Cross-over, Relative Bioavailability Study of Nicotine Delivery and Nicotine Extraction From Oral Products

Healthy Volunteers

Sweden
Imperial Brands PLC

Completed

A Randomised, Cross-Over, Nicotine Pharmacokinetic and Pharmacodynamic Study of Heated Tobacco Products Compared to Combustible Cigarettes

Healthy Volunteers

United Kingdom
ARNA Genomics US Inc.
BIOMARKER-RU

Not yet recruiting

In Vitro Study of the Liquid Biopsy Test System of the Diagnostic Value, in Women With Various Forms of Breast Cancer (ARNABreast)

Breast Neoplasms
Banyan Biomarkers, Inc
United States Department of Defense

Completed

Evaluation of Biomarkers of Traumatic Brain Injury (ALERT-TBI)

Traumatic Brain Injury

United States, Hungary, Germany
Banyan Biomarkers, Inc
United States Department of Defense

Completed

Evaluation of Biomarker Kinetics After Mild Brain Injury Trauma (VIGILANT)

Traumatic Brain Injury

United States, Hungary, Germany
Imperial Brands PLC

Recruiting

Nicotine Pharmacokinetic Study of Heated Tobacco and Heated Herbal Products

Healthy Volunteers

United Kingdom
Imperial Brands PLC

Active, not recruiting

A Relative Bioavailability Study of Nicotine Delivery From Selected Oral Nicotine Products

Healthy Volunteers

Sweden
Imperial Brands PLC

Completed

A Study to Evaluate the Safety Profile of an e-Vapour Product

Healthy Volunteers

United Kingdom
Banyan Biomarkers, Inc
U.S. Army Medical Research and Development Command

Completed

EVALUATION OF BIOMARKERS OF TRAUMATIC BRAIN INJURY EXTENSION STUDY (ALERT-TBIx)

Traumatic Brain Injury

United States, Germany
Imperial Brands PLC

Completed

A Bioavailability Study of Nicotine Delivered by an Electronic Vapour Product

Healthy Volunteers

United Kingdom
Banyan Biomarkers, Inc
U.S. Army Medical Research and Development Command

Terminated

Fresh Intravenous Blood Samples for TBI Diagnostic Assay Development With Philips Point of Care System (FIRST DOWN)

Traumatic Brain Injury

Netherlands
Ospedale Regionale Bellinzona e Valli
Brahms SA, D-16761 Hennigsdorf bei Berlin

Completed

Time Course of Procalcitonin and C Reactive Protein in Septic Patients Under Treatment With Corticosteroids

Sepsis

Switzerland
Protecting Brains Saving Futures

Not yet recruiting

Protecting Brains and Saving Futures - the PBSF Protocol (PBSF)

Brain Injuries | Intraventricular Hemorrhage | Congenital Heart Disease | Hypoxic-Ischemic Encephalopathy | Newborn Morbidity | Inborn Errors of Metabolism | Extracorporeal Membrane Oxygenation Complication | Respiratory Complication | Hemodynamic Instability | Nosocomial Infection | Neonatal Seizure | Brain... and other conditions

Brazil
A.C. Abrahams

Completed

Effect of N-acetylcysteine (NAC) on Hydrogen Sulfide (H2S) in Chronic Kidney Disease (CKD)

End Stage Renal Disease | Chronic Kidney Disease | End Stage Kidney Disease | Chronic Kidney Failure

Netherlands
Northwell Health
Solace Brands, Inc.

Withdrawn

The Use of Cannabinoid Patch for Knee Osteoarthritis

Osteoarthritis | Knee Osteoarthritis | CBD

United States
Charite University, Berlin, Germany
NeuroCure Clinical Research Center, Charite, Berlin; Brahms AG

Completed

Stroke Adverse Outcome is Associated With Nosocomial Infections: PCTus- Guided Antibacterial Therapy in Severe Ischemic Stroke Patients (STRAWINSKI) (STRAWINSKI)

Ischemic Stroke

Spain, Germany
University Hospital, Basel, Switzerland
Brahms AG; Basel Institute of Clinical Epidemiology (BICE)

Completed

Procalcitonin Guided Antibiotic Use in Acute Respiratory Tract Infections (PARTI)-Study

Respiratory Tract Infections

Switzerland
Peter Brehm GmbH

Terminated

Prospective Post Market Clinical Follow-Up of the Primary Knee Endoprosthesis BPK-S Integration

Osteoarthritis, Knee | Joint Instability

Austria

Clinical Trials Sponsored by BRAHMS Biomarkers

Sponsors and Collaborators

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CROs in Estonia

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