Clinical Trials Sponsored by Carag AG

Total 2363 results

Carag AG

Suspended

Clinical Pilot Study to Evaluate a New Multi-parameter Neuromonitoring Device in Brain-injured Patients (CBMS FIH)

Brain Injuries

Switzerland
Carag AG

Completed

Safety and Effectiveness Study of the Solysafe Septal Occluder

Atrial Septal Defects

Serbia
Carag AG

Completed

Safety and Effectiveness Study of the Solysafe Septal Occluder in Patients With Atrial Septum Defect and Patent Foramen Ovale

Atrial Septal Defect | Patent Foramen Ovale

Germany
Carag AG

Not yet recruiting

Sensing Oxygen Saturations Using Abdominal NIRS With an Investigational Realtime Device (Songbird) ((Songbird))

NEC
Carag AG

Completed

FIH Study With CBSO

Atrial Septal Defect (ASD) | Patent Foramen Ovale (PFO)

Germany
Carag AG

Completed

NIRS to Monitor Abdominal Tissue Oxygen Saturation in Preterm Infants (CTOM-FIH)

Neonatal Disorder

Switzerland
Cara Medical Ltd

Recruiting

Cara CDRS (Conduction Disturbance Risk Score) 1.0 (CDRS)

Transcatheter Aortic Valve Replacement

Spain, Canada, Italy
Cara Medical Ltd

Recruiting

Cara CDRM (Conduction Disturbance Risk Monitor) 2.0 (Cara CDRM)

Transcatheter Aortic Valve Replacement

United States
Cara Therapeutics, Inc.

Terminated

CR845-310302: A Study to Evaluate the Safety and Efficacy of Difelikefalin in Advanced Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus

Chronic Kidney Diseases | Pruritus

United States, Hungary, Australia, Germany, Korea, Republic of, Poland, Argentina, Brazil, Bulgaria, Italy, Mexico, Romania, Spain
Cara Therapeutics, Inc.

Completed

CR845-100303: Study to Assess the Potential of Physical Withdrawal From Intravenous CR845 (Difelikefalin) in Hemodialysis Patients

Hemodialysis

United States
Cara Therapeutics, Inc.

Completed

CR845-CLIN3105: A Study to Evaluate the Safety and Effectiveness of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus

Uremic Pruritus

United States, Czechia, Hungary, Poland
Cara Therapeutics, Inc.

Completed

Extension Study to Evaluate IV CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus

Uremic Pruritus

United States, Puerto Rico
Cara Therapeutics, Inc.

Completed

Study to Evaluate the Pharmacokinetics and Metabolism of [14C] CR845 (Difelikefalin) in Patients With End Stage Renal Disease on Hemodialysis and in Healthy Subjects

Healthy | Hemodialysis

United States
Cara Medical Ltd

Recruiting

Intra-procedural ECG Changes During TAVR

Transcatheter Aortic Valve Replacement | Conduction Disturbance

United States
Cara Therapeutics, Inc.

Completed

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin (CR845) for Moderate to Severe Pruritus in Subjects With Notalgia Paresthetica (KOMFORT)

Pruritus | Notalgia Paresthetica

United States, Canada
Cara Therapeutics, Inc.

Approved for marketing

Intermediate-Size Patient Population Expanded Access Program for Intravenous Difelikefalin

Uremic Pruritus
Cara Therapeutics, Inc.

Completed

CR845-CLIN3103: A Global Study to Evaluate the Safety and Efficacy of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus (KALM-2)

Uremic Pruritus

United States, Canada, Czechia, Australia, Germany, Hungary, Korea, Republic of, New Zealand, Poland, Taiwan, United Kingdom
Cara Therapeutics, Inc.

Completed

Study to Evaluate IV CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus

Uremic Pruritus

United States
Cara Therapeutics, Inc.

Completed

A Study Evaluating the Overall Pain Relief and Safety of Intravenous (IV) CR845 in Patients Undergoing Abdominal Surgery

Post Abdominal Surgery Pain

United States
Cara Therapeutics, Inc.

Completed

Study to Evaluate Analgesic Effect of IV Administration of Kappa Agonist CR845 For Hysterectomy Surgery

Postoperative Pain

United States
Cara Therapeutics, Inc.

Recruiting

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin for Moderate to Severe Pruritus in Subjects With Notalgia Paresthetica

Pruritus | Notalgia Paresthetica

United States, Poland, Spain, Canada, Germany
Cara Therapeutics, Inc.

Terminated

A Study to Evaluate the Safety and Efficacy of Difelikefalin in Advanced Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus

Chronic Kidney Diseases | Pruritus

United States
Cara Therapeutics, Inc.

Terminated

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin as Adjunct Therapy to a Topical Corticosteroid for Moderate to Severe Pruritus in Subjects With Atopic Dermatitis (KIND-1)

Pruritus | Atopic Dermatitis

United States
Cara Therapeutics, Inc.

Completed

A Study to Evaluate the Safety and Efficacy of CR845 in Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus

Chronic Kidney Diseases | Pruritus

United States
Cara Therapeutics, Inc.

Terminated

Study to Evaluate the Safety and Efficacy of Oral CR845 (Difelikefalin) in Patients With Primary Biliary Cholangitis (PBC) and Moderate-to-Severe Pruritus

Cholestatic Pruritus

United States
Cara Therapeutics, Inc.

Completed

A Study to Evaluate the Safety and Efficacy of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus (KALM-1)

Uremic Pruritus

United States
Cara Therapeutics, Inc.

Completed

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin (CR845) for Moderate to Severe Pruritus in Subjects With Atopic Dermatitis (KARE)

Pruritus | Atopic Dermatitis

United States, Canada
Cara Therapeutics, Inc.

Completed

A Study Evaluating Pain Relief and Safety of Orally Administered CR845 in Patients With Osteoarthritis of Hip or Knee

Arthritis | Joint Diseases | Musculoskeletal Diseases | Rheumatic Diseases | Osteoarthritis, Knee | Osteoarthritis, Hip

United States
Cara Therapeutics, Inc.

Completed

Study to Investigate the Effects of Single Intravenous Doses of Difelikefalin (CR845) on the QTc Interval in Healthy Subjects

Healthy

United States
Cara Therapeutics, Inc.

Completed

A Study of the Safety and Effectiveness of Orally Administered CR845 in Patients With Osteoarthritis of the Hip or Knee

Osteoarthritis

United States
Cara Therapeutics, Inc.

Completed

Safety and Pharmacokinetics of IV CR845 in Hemodialysis Patients, and Its Efficacy in Patients With Uremic Pruritus

Pruritus | Uremic Pruritus

United States
Cara Therapeutics, Inc.

Completed

Study to Evaluate Analgesic Effect of Intravenous Administration of Kappa Agonist CR845 After Hysterectomy Surgery

Acute Pain

United States
Cara Therapeutics, Inc.

Completed

A Phase 2 Study to Evaluate Analgesic Effect of IV CR845 For Pain Following Bunionectomy Surgery

Acute Pain

United States
Marwa Mohamed Farag

Completed

Placental Transfusion Effect on Hemodynamics of Premature Newborns

Pre-Term

Egypt
Sherif S. Farag

Completed

Sitagliptin for Prevention of Acute Graft Versus-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation

Hematopoietic Stem Cell Transplantation | Graft vs Host Disease

United States
Marwa Mohamed Farag

Completed

Anemia of Prematurity and Hemodynamics

Premature

Egypt
Marwa Mohamed Farag

Completed

The Relationship Between Superior Vena Cava Flow and Intraventricular Hemorrhage in Preterm Infants

Preterm Intraventricular Hemorrhage

Egypt
Sherif S. Farag

Withdrawn

Analysis of Oral Mucositis in Patient's Undergoing Melphalan Conditioning and Autologous Stem Cell Transplant

Multiple Myeloma | Amyloidosis | Mucositis | Oral Mucositis

United States
Marwa Mohamed Farag

Completed

Near-infrared Spectroscopy in Cerebral Oxygenation Monitoring in Full Term Neonates

Cerebral Oxygenation in Full-term Neonates

Egypt
Sara Farag

Completed

Urinary Retention After Total Laparoscopic Hysterectomy With Immediate Foley Catheter Removal Versus Backfill Void Trial

Voiding Disorders | Urinary Retention

United States
Bottneuro AG
Hemex AG

Active, not recruiting

Evaluate the Safety and Feasibility of tACS With the Miamind Neurostimulator in Healthy Participants (MindStim)

Healthy Participants | Healthy Population

Switzerland
Tetec AG
Aesculap AG

Completed

Non-Interventional Study to Evaluate Safety and Efficacy of NOVOCART 3D in Patients With Cartilage Defects (NISANIK)

Cartilage Diseases

Germany
Santersus AG
ISS AG

Not yet recruiting

Safety, Tolerability and Performance of the NucleoCapture Device in the Reduction of Circulating cfDNA/NETs in Subjects With Sepsis (NUC-CAP)

Sepsis | Respiratory Failure

United Kingdom, Germany, Switzerland
SynDermix AG
ISS AG

Withdrawn

Safety and Efficacy of SDX-3101 for the Treatment of Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP) (SDX-3101)

Chronic Rhinosinusitis Without Nasal Polyps

Germany, Austria, Switzerland
Tetec AG
Aesculap AG

Completed

Observational Study With NOVOCART® Inject in the Reconstruction of the Hip Joint With Full Thickness Cartilage Defects (HIP-ACTION)

Cartilage Disease

Germany
Marwa Mohamed Farag

Completed

Echocardiographic Findings in Infants of Diabetic Mothers and Its Relation to Maternal Glycemic Control

Infant of Diabetic Mother

Egypt
Marwa Mohamed Farag

Completed

Echocardiographic Screening of Healthy Neonates for Measuring Pulmonary Artery Pressure

Pulmonary Hypertension of Newborn

Egypt
Sherif S. Farag

Terminated

Phase 2 Haplotype Mismatched HSCT in Patients With Hematological Malignancies

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Chronic Myeloid Leukemia | Myelodysplasia

United States
Amina Fouad Farag

Completed

Diagnostic and Prognostic Accuracy of Gold Nanoparticles in Salivary Gland Tumours

Carcinoma Ex Pleomorphic Adenoma of Salivary Glands | Pleomorphic Adenoma of Salivary Glands

Egypt
Cara Donohue

Withdrawn

Fatigue in Patients With Amyotrophic Lateral Sclerosis

Respiration Disorders | Amyotrophic Lateral Sclerosis | Dysphagia | Dyspnea

United States

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