Clinical Trials Sponsored by Cognition Pharmaceuticals, LLC

Total 646 results

Cognition Pharmaceuticals, LLC

Completed

A Study of C105 on Cognitive Dysfunction in Persons With Multiple Sclerosis

Multiple Sclerosis | Cognition Disorders

United States
Cognitive Research Corporation
Novartis Pharmaceuticals

Withdrawn

Exploratory Study Evaluating the Effects of Darifenacin on Nocturia, Sleep and Daytime Wakefulness

Nocturia
Concert Pharmaceuticals
Cognitive Research Corporation

Completed

A Phase 2 Study to Evaluate the Safety and Efficacy of CTP-692 as an Adjunctive Treatment in Adults With Schizophrenia

Schizophrenia

United States
Honeybrains Biotech LLC
Cognitive Research Corporation

Completed

Safety and Efficacy of HB-1 for Panic Disorder

Panic Disorder

United States
Neurana Pharmaceuticals, Inc.
Cognitive Research Corporation

Completed

Driving Simulation to Assess Non-Sedative Effects of Tolperisone

Driving Impaired

United States
RVL Pharmaceuticals, Inc.
Osmotica Pharmaceutical US LLC

Completed

A Study to Evaluate the Long-term Safety of Arbaclofen Extended-Release Tablets for Patients With Spasticity Due to MS (OS440-3005)

Multiple Sclerosis | Spasticity, Muscle

United States
RVL Pharmaceuticals, Inc.
Osmotica Pharmaceutical US LLC

Withdrawn

To Assess Effects of Arbaclofen ER Tablets Compared With Placebo on Sperm Parameters in Male Subjects With MS

Multiple Sclerosis | Sperm

United States
RVL Pharmaceuticals, Inc.
Osmotica Pharmaceutical US LLC

Completed

A Study to Investigate the Safety and Effectiveness of Arbaclofen Extended-Release Tablets for Patients With MS (OS440-3004)

Multiple Sclerosis | Spasticity, Muscle

Serbia, Belarus, Bosnia and Herzegovina, Bulgaria, Croatia, Moldova, Republic of, Poland
RVL Pharmaceuticals, Inc.
Osmotica Pharmaceutical US LLC

Completed

Efficacy Study of Arbaclofen to Treat Spasticity in Multiple Sclerosis

Multiple Sclerosis | Spasticity

United States, Russian Federation, Ukraine
Amneal Pharmaceuticals, LLC
Novum Pharmaceutical Research Services

Completed

Study to Compare the Therapeutic Equivalence of Mometasone Furoate Nasal Spray, 50 mcg With Nasonex Nasal Spray in the Relief of the Signs and Symptoms of Seasonal Allergic Rhinitis

Seasonal Allergic Rhinitis

United States
RVL Pharmaceuticals, Inc.
Osmotica Pharmaceutical US LLC

Completed

One Year, Open Label, Dose Escalation Long-term Safety Study in Multiple Sclerosis (MS) Subjects With Spasticity

Multiple Sclerosis | Spasticity

United States, Russian Federation, Ukraine
Biohaven Pharmaceuticals, Inc.
Cognitive Research Corporation

Completed

Open-label Study to Evaluate Safety, Tolerability and PK of BHV-0223 in ALS

Amyotrophic Lateral Sclerosis | ALS | Lou Gehrig Disease | Lou Gehrig's Disease | Lou-Gehrigs Disease | Motor Neuron Disease, Amyotrophic Lateral Sclerosis

United States
Inovio Pharmaceuticals
Coalition for Epidemic Preparedness Innovations

Completed

Safety, Tolerability and Immunogenicity of INO-4700 for MERS-CoV in Healthy Volunteers

Middle East Respiratory Syndrome Coronavirus (MERS-CoV)

Lebanon, Jordan, Kenya
Inovio Pharmaceuticals
Coalition for Epidemic Preparedness Innovations

Completed

Safety, Tolerability and Immunogenicity of INO-4500 in Healthy Volunteers

Lassa Fever

United States
Inovio Pharmaceuticals
Coalition for Epidemic Preparedness Innovations

Completed

Dose-ranging Study: Safety, Tolerability and Immunogenicity of INO-4500 in Healthy Volunteers in Ghana

Lassa Fever

Ghana
Inovio Pharmaceuticals
Coalition for Epidemic Preparedness Innovations

Completed

Safety, Tolerability and Immunogenicity of INO-4800 for COVID-19 in Healthy Volunteers

Coronavirus Infection

United States
Pharmaceutical Project Solutions, Inc.
Cognitive Research Corporation

Completed

PK Study of Intranasal RX0041-002 in Subjects With Severe Renal Impairment and Normal Renal Function

Healthy

United States
Amneal Pharmaceuticals, LLC
Symbio, LLC

Completed

Safety and Efficacy of Phenazopyridine Hydrochloride Tablets, USP 200 mg as an Analgesic for Short-Term Treatment in Female Subjects Suffering From Moderate-to-Severe Pain and Burning Upon Urination Associated With Uncomplicated Urinary Tract Infections (uUTI)

Uncomplicated Urinary Tract Infections

United States
Pharmaceutical Project Solutions, Inc.
Cognitive Research Corporation

Completed

Pharmacokinetic Study of Intranasal RX0041-002 in Hepatic-Impaired Individuals and Subjects With Normal Hepatic Function

Analgesic Allergy

United States
Saptalis Pharmaceuticals LLC
bioRASI, LLC

Completed

A Bioequivalence Study With Clinical Endpoints to Evaluate the Safety and Therapeutic Equivalence of Permethrin Cream 5% & Elimite™ in Subjects With Scabies

Scabies

United States
Hikma Pharmaceuticals LLC

Not yet recruiting

Bioequivalence of Azacitidine 300 mg Film-Coated Tablets in Adult Patients With Acute Myeloid Leukaemia (AML)

Acute Myeloid Leukaemia
Kind Pharmaceuticals LLC

Not yet recruiting

A Study of Efficacy and Safety of AND017 in Patients With Myelodysplastic Syndrome

Myelodysplastic Syndromes
Deciphera Pharmaceuticals LLC

Not yet recruiting

Study of DCC-3084 in Participants With Advanced Malignancies Driven by the Mitogen-Activated Protein Kinase (MAPK) Pathway

Melanoma | Non-Small Cell Lung Cancer | Advanced Solid Tumor | Pancreatic Ductal Adenocarcinoma | BRAF Gene Mutation | RAS Mutation | NF1 Mutation | RAF Mutation | CRAF Gene Mutation

United States
Deciphera Pharmaceuticals LLC

Recruiting

A Study of Ripretinib vs Sunitinib in Patients With Advanced GIST With Specific KIT Exon Mutations Who Were Previously Treated With Imatinib (INSIGHT)

GIST

United States, Korea, Republic of, Spain, Taiwan, Australia, Canada, United Kingdom, Italy, Netherlands, Brazil, Chile, Poland
Deciphera Pharmaceuticals LLC

Recruiting

A Phase 1/2 Study of DCC-3116 in Patients With MAPK Pathway Mutant Solid Tumors

Melanoma | Colorectal Cancer | Non-Small Cell Lung Cancer | Advanced Solid Tumor | Metastatic Solid Tumor | Pancreatic Ductal Adenocarcinoma

United States
Deciphera Pharmaceuticals LLC

Active, not recruiting

A Drug-Drug Interaction Study to Evaluate the Effect of Ripretinib on the Pharmacokinetics of a CYP2C8 Probe Substrate in Patients With Advanced GIST

GIST - Gastrointestinal Stromal Tumor

United States
MSD Pharmaceuticals LLC

Completed

ART First-line Treatment Durability in Russia

HIV-1-infection

Russian Federation
Deciphera Pharmaceuticals LLC

Active, not recruiting

A Study of Ripretinib vs Sunitinib in Advanced GIST Patients After Treatment With Imatinib (INTRIGUE)

Gastrointestinal Stromal Tumors

United States, Korea, Republic of, Norway, Spain, Netherlands, Australia, Taiwan, France, United Kingdom, Belgium, Singapore, Canada, Italy, Poland, Sweden, Hungary, Germany, Israel, Czechia, Argentina, Chile, Switzerland
Deciphera Pharmaceuticals LLC

Completed

A Safety, Tolerability and PK Study of DCC-2618 in Patients With Advanced Malignancies

Gastrointestinal Stromal Tumors | Advanced Cancers | Advanced Systemic Mastocytosis

United States, Canada, Germany, Italy, Netherlands, United Kingdom
Arjil Pharmaceuticals LLC

Terminated

A Study for AR100DP1 in Mild to Moderate Atopic Dermatitis (AD)

Dermatitis, Atopic

Taiwan
Asklepion Pharmaceuticals, LLC

Completed

L-citrulline for Prevention of Sequelae of Acute Lung Injury in Pediatrics Undergoing Cardiopulmonary Bypass for Heart Defects

Acute Lung Injury

United States, Israel, Germany, Austria
Asklepion Pharmaceuticals, LLC

Completed

Intravenous L-Citrulline Influence on the Need for Invasive Mechanical Ventilation for Acute Hypoxemic Respiratory Failure in Patients With COVID-19

Acute Hypoxemic Respiratory Failure

United States
Yamo Pharmaceuticals LLC

Completed

Safety of L1-79 in Autism

Autism

United States
Asklepion Pharmaceuticals, LLC

Completed

Intravenous L-Citrulline to Treat Children Undergoing Heart Bypass Surgery : Revised Protocol

Atrial Septal Defect | Atrioventricular Septal Defect | Ventricular Septal Defect

United States
Cali Pharmaceuticals LLC

Completed

A Phase 2, Randomized, Double-Blind, Dose Escalation Study in Postoperative Pain Open Inguinal Herniorrhaphy

Inguinal Herniorrhaphy

United States
Salarius Pharmaceuticals, LLC

Completed

Phase 1 Trial of the LSD1 Inhibitor SP-2577 (Seclidemstat) in Patients With Advanced Solid Tumors

Advanced Solid Tumors

United States
Patagonia Pharmaceuticals, LLC

Completed

A Safety and Tolerability Study of Topical PAT-001 in Congenital Ichthyosis

Congenital Ichthyosis

United States
Kind Pharmaceuticals LLC

Completed

A Food-Effect Study of AND017 in Healthy Participants

Healthy Volunteers

China
Curatek Pharmaceuticals, LLC

Completed

Multi-Center Study of New Medications to Treat Vaginal Infections (SMART GIVES)

Vaginal Infection

United States
Deciphera Pharmaceuticals LLC

Approved for marketing

Expanded Access Program of Ripretinib (DCC-2618) for the Treatment of Patients With Advanced GIST

GIST - Gastrointestinal Stromal Tumor
Cubist Pharmaceuticals LLC

Completed

PK and Safety Evaluation of Daptomycin in Children Ages 2-6 With Proven or Suspected Gram-positive Infections

Gram Positive Infection | Concurrent Antibiotic Treatment

United States
Cubist Pharmaceuticals LLC

Completed

Plasma Pharmacokinetics (PK) & Lung Penetration of Ceftolozane/Tazobactam in Participants With Pneumonia (MK-7625A-007)

Pneumonia | Critically Ill
Cubist Pharmaceuticals LLC

Completed

Tedizolid Phosphate (TR-701 FA, MK-1986) vs Linezolid for the Treatment of Nosocomial Pneumonia (MK-1986-002)

Pneumonia
Wellesley Pharmaceuticals, LLC

Completed

Paxerol™ for Treatment of Nocturia - A Phase II Placebo-Controlled Trial

Nocturia

United States
Cubist Pharmaceuticals LLC

Terminated

Efficacy and Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation

Opioid-Induced Constipation
Cubist Pharmaceuticals LLC

Completed

Safety and Efficacy Study to Compare IV CXA 101/Tazobactam and Metronidazole With Meropenem in Complicated Intraabdominal Infections

Complicated Intra-abdominal Infection

United States, Argentina, Serbia, Georgia, Russian Federation
Cubist Pharmaceuticals LLC

Completed

Study Comparing the Safety and Efficacy of Intravenous CXA-201 and Intravenous Levofloxacin in Complicated Urinary Tract Infection, Including Pyelonephritis

Pyelonephritis | Complicated Urinary Tract Infection

Colombia, Israel, United States, Romania, Serbia, Estonia, Russian Federation, Brazil, Hungary, Slovakia, Mexico, South Africa, Latvia, Thailand, Moldova, Republic of, Germany, Georgia
Cubist Pharmaceuticals LLC

Completed

Safety and Efficacy of IV CXA-101 and IV Ceftazidime in Patients With Complicated Urinary Tract Infections

Complicated Urinary Tract Infection

United States, Germany, Poland
Optimer Pharmaceuticals LLC

Completed

Safety and Efficacy of Fidaxomicin Versus Placebo for Prophylaxis Against Clostridium Difficile-Associated Diarrhea in Adults Undergoing Hematopoietic Stem Cell Transplantation (MK-5119-001) (DEFLECT-1)

Clostridium Difficile-Associated Diarrhea (CDAD)
Cubist Pharmaceuticals LLC

Completed

Safety and Efficacy Study of Daptomycin in Pediatric Participants (1 to 17 Years-old) With Skin and Skin Structure Infections

Skin Diseases, Infectious

United States, India, Panama

Clinical Trials Sponsored by Cognition Pharmaceuticals, LLC

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CROs in Malta

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