Clinical Trials Sponsored by Dignity Sciences Ltd.

Total 552 results

Dignity Sciences Ltd.

Completed

Oral DS107 in Moderate to Severe Atopic Dermatitis

Atopic Dermatitis

United States, Canada
Nimble Science Ltd.
IGY Life Sciences

Recruiting

Evaluation of the Microbiome in Multiple Sclerosis

Multiple Sclerosis

Canada
Wave Life Sciences Ltd.

Not yet recruiting

A Phase 1b/2a, Open-label Single Ascending Doses and Multiple Ascending Doses Study in Participants With Pi*ZZ AATD (RestorAATion-2)

Alpha-1 Antitrypsin Deficiency
Tiziana Life Sciences LTD

Recruiting

A Study of Nasal Foralumab in Non-Active Secondary Progressive Multiple Sclerosis Patients

Secondary Progressive Multiple Sclerosis

United States
Wave Life Sciences Ltd.

Recruiting

A Phase 1 Research Study to Evaluate Safety, Tolerability, and Pharmacokinetics of WVE-006 in Healthy Participants With Wild-type AAT Expression (RestorAATion-1) (RestorAATion-1)

Alpha-1 Antitrypsin Deficiency

United Kingdom
CANbridge Life Sciences Ltd.

Recruiting

Phase 2 Study of CAN008 in Subjects With GBM

Newly-diagnosed Glioblastoma

China
Wave Life Sciences Ltd.

Terminated

Open-label Extension (OLE) Study of WVE-004 in Patients With C9orf72-associated Amyotrophic Lateral Sclerosis (ALS) and/or Frontotemporal Dementia (FTD)

ALS | FTD

Netherlands, United Kingdom
Tiziana Life Sciences LTD

Withdrawn

In-patient COVID-19 Study of Intranasal Foralumab

Covid19 | COVID-19 Respiratory Infection | COVID-19 Lower Respiratory Infection
Wave Life Sciences Ltd.

Terminated

Safety and Tolerability of WVE-120101 in Patients With Huntington's Disease (PRECISION-HD1)

Huntington's Disease

Denmark, Canada, Australia, United Kingdom, France, Germany, Poland
Wave Life Sciences Ltd.

Terminated

Open-label Extension Study to Evaluate the Safety and Tolerability of WVE-120102 in Patients With Huntington's Disease

Huntington Disease

Denmark, Australia, Canada, France, United Kingdom, Germany, Poland
Tiziana Life Sciences LTD

Withdrawn

Assessment of the Safety of Foralumab, an Oral Anti-CD3 Antibody, in Patients With NASH and T2DM

NAFLD | NASH - Nonalcoholic Steatohepatitis | T2DM (Type 2 Diabetes Mellitus)
Wave Life Sciences Ltd.

Completed

Safety and Tolerability of WVE-210201 in Patients With Duchenne Muscular Dystrophy

Duchenne Muscular Dystrophy

Belgium, United Kingdom, France, United States, Italy, Canada, Netherlands
Wave Life Sciences Ltd.

Recruiting

Study of WVE-003 in Patients With Huntington's Disease

Huntington Disease

Canada, Spain, Australia, Denmark, Netherlands, Poland, United Kingdom, France, Germany, Italy
Avacta Life Sciences Ltd

Recruiting

A Study Evaluating the Safety, Pharmacokinetics and Early Efficacy of AVA6000 in Solid Tumours

Soft Tissue Sarcoma | Breast Cancer | Head and Neck Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Prostate Cancer | Bladder Cancer | Non-small Cell Lung Cancer | Biliary Tract Cancer | Oesophageal Cancer | Cancer of Unknown Primary Site

United States, United Kingdom
Tiziana Life Sciences LTD

Withdrawn

A Study of Oral Foralumab in Participants With Moderate to Severely Active Crohn's Disease

Crohn's Disease
Wave Life Sciences Ltd.

Terminated

Safety and Tolerability of WVE-120102 in Patients With Huntington's Disease (PRECISION-HD2)

Huntington's Disease

United States, Denmark, Canada, Australia, United Kingdom, France, Germany, Poland
Tiziana Life Sciences LTD

Withdrawn

Phase 1b Multiple Ascending Dose Study of Foralumab in Primary and Secondary Progressive MS

Multiple Sclerosis | Primary Progressive Multiple Sclerosis | Secondary Progressive Multiple Sclerosis
Wave Life Sciences Ltd.

Terminated

Open-label Extension Study to Evaluate the Safety and Tolerability of WVE-120101 in Patients With Huntington's Disease

Huntington Disease

Denmark, Australia, Canada, France, United Kingdom, Germany, Poland
Tiziana Life Sciences LTD

Completed

Study of Milciclib in Patients With Unresectable/Metastatic Hepatocellular Carcinoma

Hepatocellular Carcinoma

Israel, Greece, Italy
Wave Life Sciences Ltd.

Terminated

Efficacy and Safety Study of WVE-210201 (Suvodirsen) With Open-label Extension in Ambulatory Patients With Duchenne Muscular Dystrophy (DYSTANCE 51)

Duchenne Muscular Dystrophy

United States, Belgium, United Kingdom, Czechia, Canada, France, Italy, Sweden
CANbridge Life Sciences Ltd.

Completed

A Study of CAN008 for Newly Diagnosed Glioblastoma Multiforme

Glioblastoma Multiforme

Taiwan
CANbridge Life Sciences Ltd.

Unknown

CAN008 Biomarker CD95 Ligand and CpG2 Methylation in Chinese Patients With Glioblastoma

Glioblastoma
Clinical Life Sciences Ltd.

Completed

Effect of Plant Stanol Esters on Blood Lipids

Elevated Blood Lipids

Finland
Nimble Science Ltd.

Not yet recruiting

The Digestion of Protein Powders in Healthy Participants Using SIMBA and LIMBA Capsule

Nutrition | Microtia | Amino Acid Change | Food Science | Digestion Rate

Canada
Tiziana Life Sciences LTD

Not yet recruiting

Milciclib in Combination With Gemcitabine in Advanced NSCLC

NSCLC
Wave Life Sciences Ltd.

Active, not recruiting

Open-label Study of WVE-N531 in Patients With Duchenne Muscular Dystrophy (FORWARD-53)

Duchenne Muscular Dystrophy

Jordan, United Kingdom
Wave Life Sciences Ltd.

Terminated

Study of WVE-004 in Patients With C9orf72-associated Amyotrophic Lateral Sclerosis (ALS) or Frontotemporal Dementia (FTD) (FOCUS-C9)

ALS | FTD

Canada, Belgium, New Zealand, Netherlands, Australia, Sweden, United Kingdom, Ireland
Tiziana Life Sciences LTD

Terminated

Study Of Oral PHA-848125AC In Patients With Malignant Thymoma Previously Treated With Multiple Lines Of Chemotherapy

Malignant Thymoma

United States, Italy
Tiziana Life Sciences LTD

Terminated

Phase II Study Of Oral PHA-848125AC In Patients With Thymic Carcinoma

Thymic Carcinoma

United States, France, Italy
CANbridge Life Sciences Ltd.

Unknown

To Evaluate the Efficacy and Safety of CAN008 Combined With Re-irradiation (rRT) for Treating Patients With Recurrent Glioblastoma (GBM)

GBM
Nimble Science Ltd.

Recruiting

Evaluation of the SIMBA Capsule for Small Intestinal Dysbiosis

Functional Dyspepsia | Irritable Bowel Syndrome | Celiac Disease | Crohn Disease | Ulcerative Colitis

Canada
Meril Life Sciences Pvt. Ltd.

Not yet recruiting

Non-inferiority Clinical Trial to Compare the Safety and Performance of MeRes100 Sirolimus-eluting BioResorbable Vascular Scaffold System Versus Contemporary DES Platforms in Patients With de Novo Coronary Artery Lesions (MeRethonRCT)

Coronary Artery Disease
Meril Life Sciences Pvt. Ltd.

Recruiting

LANDMARK Trial: a Randomised Controlled Trial of Myval THV (LANDMARK)

Aortic Valve Stenosis

Sweden, Hungary, France, Belarus, Croatia, Germany, Netherlands, New Zealand, Poland, Portugal, Slovakia, Slovenia, Spain, Italy, Brazil, Estonia, Greece
Actimed Therapeutics Ltd
Quotient Sciences

Completed

Study of Comparative Bioavailability and Pharmacokinetics of ACM-001.1) and Pindolol in Healthy Volunteers (HV)

Cachexia

United Kingdom
Galmed Pharmaceuticals Ltd
Quotient Sciences

Completed

An Open-Label, Two-Part Study Designed to Assess the Absolute Bioavailability and Mass Balance of Aramchol

NASH

United Kingdom
Meril Life Sciences Pvt. Ltd.

Unknown

A Prospective, Single-arm, Multi-centre, Observational, Real World Registry (Morpheus)

Angina Pectoris

Jordan, Hungary, Malaysia, Netherlands
Ivy Life Sciences, Co., Ltd

Completed

Study of Autologous Immune Killer Cells in Patients With Late Stage Hepatocellular Carcinoma or Lung Cancer

Lung Cancer | Liver Cancer | NSCLC Stage IV | Hepatocellular Carcinoma by BCLC Stage | NSCLC Stage IIIB
Meril Life Sciences Pvt. Ltd.

Completed

An Evaluation of BioMime™ - Sirolimus Eluting Coronary Stent in a Multi- Centre Study. (meriT-2)

Coronary Artery Disease

India
Neuramedy Co. Ltd.
Quotient Sciences

Not yet recruiting

Single and Multiple Ascending Dose Study to Assess Safety, Tolerability and Pharmacokinetics of NM-101

Parkinson Disease

United Kingdom
Meril Life Sciences Pvt. Ltd.

Recruiting

Myval Global Study of Myval™ THV Series Implanted in Patients With Native Severe Aortic Valve Stenosis.

Aortic Valve Stenosis

Slovenia, Spain, Turkey, Italy, Netherlands, Estonia, Poland
Galmed Pharmaceuticals Ltd
Quotient Sciences

Completed

A First-in-Human Study of Single and Multiple Doses of Amilo-5MER in Healthy Subjects

Inflammatory Disease

United Kingdom
Meril Life Sciences Pvt. Ltd.

Unknown

Clinical Study Comparing Single Long BioMimeTM Morph Coronary Stent System vs. Two Overlapping Xience Family Coronary Stent Systems in the Treatment of Patients With Long de Novo Lesions. (Morph RCT-1)

Coronary Artery Disease
Meril Life Sciences Pvt. Ltd.

Unknown

Pilot Clinical Study of MeRes100 Sirolimus Eluting Bioresorbable Vascular Scaffold System (MeRes-1Extend)

Coronary Artery Disease

Malaysia, Brazil, Indonesia, Macedonia, The Former Yugoslav Republic of
Meril Life Sciences Pvt. Ltd.

Not yet recruiting

Freedom® Total Knee System for Treatment of Osteoarthritis, Rheumatoid Arthritis or Post-traumatic Arthritis (Freedom®450)

Rheumatoid Arthritis | Knee Osteoarthritis | Post-traumatic Osteoarthritis
Meril Life Sciences Pvt. Ltd.

Not yet recruiting

Study of MeRes100 in the Treatment of Patient With Coronary Artery Disease. (MeReS100-China)

Coronary Artery Disease
Meril Life Sciences Pvt. Ltd.

Unknown

BioMime Vs. Xience Randomised Control Clinical Study (meriT-V)

Coronary Artery Disease

United Kingdom, Brazil, Spain, Macedonia, The Former Yugoslav Republic of, Belgium, Czechia, Latvia, Netherlands, Poland
Clinical Life Sciences Ltd.
Fazer

Completed

Measurement of Glycaemic Responses of Bakery and Confectionery Products (GIFA)

Healthy

Finland
Neuracle Science Co., LTD.

Completed

A FIH Study to Assess the Safety and Tolerability of NS Intravenous NS101 Infusion

Neurodegenerative Diseases

Canada
Oplon-Pure Science Ltd.

Completed

Acne Treatment With Active Patches Which Contains Azelaic Acid, Citric Acid,Salicylic Acid and 2% Ascorbic Acid

Acne Vulgaris

Israel
Brlev Agricultural Crops Ltd
Bio-Sciences Pharma Ltd.

Terminated

Treatment With Cannabis Oil Containing CBD, THC, CBDV or CBG vs. Placebo of Persons With ADHD

ADHD | Hyperactivity | Attention Deficit

Israel

Clinical Trials Sponsored by Dignity Sciences Ltd.

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