Clinical Trials Sponsored by Dyne Therapeutics

Total 6472 results

Dyne Therapeutics

Recruiting

Safety, Tolerability, Pharmacodynamic, Efficacy, and Pharmacokinetic Study of DYNE-251 in Participants With Duchenne Muscular Dystrophy Amenable to Exon 51 Skipping (DELIVER)

Duchenne Muscular Dystrophy (DMD)

United States, Belgium, Canada, United Kingdom, Australia, Spain, Italy
Dyne Therapeutics

Recruiting

Safety, Tolerability, Pharmacodynamic, Efficacy, and Pharmacokinetic Study of DYNE-101 in Participants With Myotonic Dystrophy Type 1 (ACHIEVE)

Myotonic Dystrophy Type 1 (DM1)

United Kingdom, France, Netherlands, Italy, Germany, New Zealand
Vyne Therapeutics Inc.

Completed

VPD-737 for Treatment of Chronic Pruritus

Chronic Pruritus

United States
Vyne Therapeutics Inc.

Completed

A Study to Compare the Efficacy and Safety of Topical Administration of FMX-101 for Treatment of Moderate-to-Severe Acne

Acne Vulgaris

United States, Dominican Republic
Vyne Therapeutics Inc.

Completed

A Study to Compare the Efficacy and Safety of Topical Administration of FMX-101 for Treatment of Moderate-to-Severe Acne

Acne Vulgaris

United States, Dominican Republic
Vyne Therapeutics Inc.

Completed

Study of the Efficacy, Safety, and Tolerability of Serlopitant for the Treatment of Refractory Chronic Cough

Refractory Chronic Cough

United States, United Kingdom
Vyne Therapeutics Inc.

Terminated

Study of the Efficacy, Safety & Tolerability of Serlopitant for Pruritus (Itch) After Burn Injury (AUBURN)

Burns | Pruritus

United States
Vyne Therapeutics Inc.

Completed

Study of the Efficacy, Safety and Tolerability of Serlopitant for the Treatment of Pruritus (Itch) With Prurigo Nodularis

Pruritus | Prurigo Nodularis

United States
Vyne Therapeutics Inc.

Terminated

A Study of MK0594 in Patients With Alcohol Dependence (0594-020)

Alcohol Dependence
Vyne Therapeutics Inc.

Completed

Safety and Efficacy Study of a Topical Minocycline Foam in Patients With Papulopustular Rosacea (EMIRA)

Rosacea | Papulopustular Rosacea

Germany
Vyne Therapeutics Inc.

Completed

A Study to Evaluate the Efficacy and Safety of Topical Administration of FMX101 in the Treatment of Moderate-to-Severe Acne Vulgaris

Acne Vulgaris

United States
Vyne Therapeutics Inc.

Completed

A Study to Evaluate the Long-Term Safety of Topical Administration of FMX103 in the Treatment of Moderate to Severe Papulopustular Rosacea

Papulopustular Rosacea

United States
Vyne Therapeutics Inc.

Completed

Study of the Efficacy, Safety and Tolerability of Serlopitant for the Treatment of Pruritus (Itch) With Plaque Psoriasis

Psoriasis | Pruritus

United States
Vyne Therapeutics Inc.

Terminated

Study of the Long Term Safety of Serlopitant for the Treatment of Pruritus (Itch)

Psoriasis | Pruritus | Atopic Dermatitis | Prurigo Nodularis

United States, Austria, Germany, Poland
Vyne Therapeutics Inc.

Completed

Study of the Efficacy, Safety, and Tolerability of Serlopitant for the Treatment of Chronic Pruritus of Unknown Origin

Pruritus

United States
Vyne Therapeutics Inc.

Completed

A Study to Compare FCD105 Foam to Minocycline 3% Foam, Adapalene 0.3% Foam and Vehicle Foam.

Acne Vulgaris

United States
Vyne Therapeutics Inc.

Completed

Dermal Cumulative Irritant Patch Study

Healthy
Vyne Therapeutics Inc.

Completed

A Randomized, Controlled Study to Evaluate the Sensitizing Potential of FMX-101 in Healthy Volunteers Using a Repeat Insult Patch Test Design

Healthy
Vyne Therapeutics Inc.

Completed

Clinical Study to Evaluate Tolerability and Safety of FXFM244 and to Monitor Clinical Effect in Acne Vulgaris Patients

Acne Vulgaris

Israel
Vyne Therapeutics Inc.

Completed

Safety, Pharmacokinetics and Efficacy of FMX114 Versus Vehicle in Adults With Atopic Dermatitis

Atopic Dermatitis

United States, Australia
Vyne Therapeutics Inc.

Completed

A Randomized Placebo-Controlled Study of the Neurokinin-1 (NK1) Receptor Antagonist Serlopitant Prurigo Nodularis (PN)

Prurigo Nodularis

Germany
Vyne Therapeutics Inc.

Completed

Study of the Efficacy, Safety, and Tolerability of Serlopitant for Pruritus (Itch) in Atopic Dermatitis (ATOMIK)

Pruritus | Atopic Dermatitis

United States
Vyne Therapeutics Inc.

Completed

Study of the Efficacy, Safety and Tolerability of Serlopitant for the Treatment of Pruritus (Itch) With Prurigo Nodularis

Pruritus | Prurigo Nodularis

Austria, Germany, Poland
Vyne Therapeutics Inc.

Completed

Safety and Efficacy of MK0594 to Treat Overactive Bladder (0594-003)

Overactive Bladder | Urinary Incontinence
Vyne Therapeutics Inc.

Completed

A Study Comparing Two Topicals in the Treatment of Acne Vulgaris

Acne Vulgaris

United States
Vyne Therapeutics Inc.

Completed

A Pharmacokinetic Study of Minocycline in Male and Female Volunteers

Acne

Israel
Vyne Therapeutics Inc.

Completed

Dermal Phototoxicity Study

Healthy
Vyne Therapeutics Inc.

Completed

Dermal Photo Allergic Skin Reaction

Healthy
Vyne Therapeutics Inc.

Completed

Safety, Tolerability and Efficacy Study of Doxycycline Foam for the Prevention of EGFRI Skin Toxicity in Cancer Patients

Rash Due to Epidermal Growth Factor Receptor Inhibitors

Israel
Vyne Therapeutics Inc.

Terminated

Study to Evaluate the Safety and Efficacy of Topical Minocycline FXFM244 in Rosacea Patients

Rosacea

Israel
Vyne Therapeutics Inc.

Completed

Study to Evaluate the Safety and Efficacy of Topical Minocycline FXFM244 in Impetigo Patients

Impetigo

Israel
Bukwang Pharmaceutical
Dyna Therapeutics

Completed

A Study to Evaluate Safety, Tolerability, and Pharmacokinetics of SOL-804 in Healthy Male Subjects

Prostate Cancer

Korea, Republic of
M. Arkin 1999 Ltd.
Vyne Therapeutics Inc.

Completed

Clinical Study to Evaluate Tolerability and Safety of ARK-E021 Foam and to Monitor Clinical Effect in Acne Vulgaris Patients

Acne Vulgaris

Israel
Vyne Therapeutics Inc.
Premier Research Group plc

Completed

A Study (Study 1) to Evaluate the Safety and Efficacy of FMX103 1.5% Topical Minocycline Foam in the Treatment of Facial Papulopustular Rosacea

Facial Papulopustular Rosacea

United States
Vyne Therapeutics Inc.
Premier Research Group plc

Completed

A Study (Study 2) to Evaluate the Safety and Efficacy of FMX103 1.5% Topical Minocycline Foam in the Treatment of Facial Papulopustular Rosacea

Facial Papulopustular Rosacea

United States
VDyne, Inc.

Recruiting

Clinical Safety and Efficacy of the VDyne Transcatheter Tricuspid Valve Replacement System for the Treatment of Tricuspid Regurgitation ( VISTA-US) (VISTA-US)

Tricuspid Regurgitation | Tricuspid Valve Disease | Tricuspid Valvular Disorders

United States
Mylan Inc.
Vyne Therapeutics Inc.; DPT Laboratories, Ltd.

Completed

A Dose Ranging Vehicle Controlled Study to Determine the Safety and Efficacy of Permethrin Foam, 5% and Permethrin Foam, 4% for the Treatment of Scabies

Scabies

United States, Dominican Republic, Honduras, Puerto Rico
VDyne, Inc.

Recruiting

Clinical Safety and Efficacy of the VDyne Transcatheter Tricuspid Valve Replacement System for the Treatment of Tricuspid Regurgitation (VISTA)

Tricuspid Regurgitation | Tricuspid Valve Disease | Tricuspid Valvular Disorders

Australia, Czechia, Austria
Resolve Therapeutics
Newcastle-upon-Tyne Hospitals NHS Trust; University Hospital Birmingham

Completed

A Study of RSLV-132 in Subjects With Primary Sjogren's Syndrome (RSLV-132)

Sjogren's Syndrome

United Kingdom
Dune Medical Devices

Unknown

In Vivo Smart Biopsy Device Protocol In Radiology

Breast Cancer | Image Guided Biopsy

Israel
Dune Medical Devices

Completed

Intraoperative Use of the BP Device for Detecting Positive Margins During Lumpectomy Procedure

Breast Cancer

Israel
Edward Lain, MD
Vyne Therapeutics Inc.

Completed

A Companion Treatment Study for Patients With Moderate to Severe Acne Vulgaris

Acne Vulgaris

United States
Jean Yuh Tang
Vyne Therapeutics Inc.; Epidermolysis Bullosa Research Partnership

Completed

Neurokinin-1 Receptor Antagonist for the Treatment of Itch in EB Patients

Pruritus | Epidermolysis Bullosa

United States
Dyve Biosciences, Inc.

Completed

Topical Application to Relieve Gout: Efficacy Trial & Safety (TARGETS) (TARGETS)

Gout

United States
Dune Medical Devices

Active, not recruiting

MarginProbe® System U.S. Post-Approval Study

Breast Cancer

United States
Dune Medical Devices

Completed

MarginProbe, a Device for Intraoperative Assessment of Margin Status in Breast Conservation Surgery (Pivotal)

Breast Cancer

United States, Israel
Nu Eyne Co., Ltd.

Recruiting

Study of Application of Transcutaneous Pulsed Electrical Stimulation Around Eye in Age-related Macular Degeneration

Early to Moderate Dry Age-Related Macular Degeneration

Korea, Republic of
Nu Eyne Co., Ltd.

Completed

The Evaluation of the Transcutaneous Electrical Stimulation Medical Device's Safety and Effectiveness in Treating the Patients With Migraine

Migraine

Korea, Republic of
Nu Eyne Co., Ltd.

Completed

Application of Pulse Electrical Stimulation Around Eye in Dry Eye Disease Patients Scheduled for LASEK Surgery

Dry Eye Disease

Korea, Republic of
Ranok Therapeutics (Hangzhou) Co., Ltd.

Recruiting

A Study of RNK05047 in Subjects With Advanced Solid Tumors/Diffuse Large B-cell Lymphoma (CHAMP-1)

Advanced Solid Tumor | DLBCL

United States

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