Clinical Trials Sponsored by ESPA Research

Total 40202 results

Northumbria University
ESPA Research; a2 Milk Company Ltd.

Completed

a2 Milk for Autism and Attention-deficit Hyperactivity Disorder (ADHD) (A2MT)

Autism Spectrum Disorder | Attention Deficit Hyperactivity Disorder | Autism

United Kingdom
Cross Research S.A.
Zambon SpA

Completed

Riluzole Orodispersible Film Replicate Bioavailability

Bioequivalence

Switzerland
Zambon SpA
Cross Research S.A.

Completed

Drug Interaction Study of Safinamide and a BCRP Substrate, Diclofenac, Concomitantly Administered to Healthy Volunteers

Healthy

Switzerland
SIFI SpA
Sintesi Research Srl

Completed

Clinical Study to Evaluate the Efficacy and Tolerability of an Anti-inflammatory/Antibiotic Treatment Following Ocular Cataract Extraction

Cataract | Cataract Extraction

Italy, Romania, Germany
Cross Research S.A.
Zambon SpA

Completed

Safinamide Steady State Interaction With Rosuvastatin

Healthy

Switzerland
Aspa Therapeutics

Recruiting

A Study of AAV9 Gene Therapy in Participants With Canavan Disease (CANaspire)

Canavan Disease

United States
ESSA Pharmaceuticals

Recruiting

Oral EPI-7386 in Patients With Castration-Resistant Prostate Cancer (EPI-7386)

Prostate Cancer

United States, Canada
ESSA Pharmaceuticals

Terminated

Safety and Anti-Tumor Study of Oral EPI-506 for Patients With Metastatic Castration-Resistant Prostate Cancer

Genital Neoplasms, Male | Prostatic Neoplasms | Prostatic Diseases | Genital Diseases, Male

United States, Canada
ESSA Pharmaceuticals

Recruiting

EPI-7386 in Combination With Enzalutamide Compared With Enzalutamide Alone in Subjects With mCRPC

Prostate Cancer

Canada, United States, Australia
Aspa Therapeutics

Recruiting

Natural History Study of Patients With Canavan Disease

Canavan Disease

United States, Germany
University of Patras
European Society for Paediatric Research (ESPR)

Recruiting

IUGR, Respiratory Muscle Function, and Exercise Capacity in Childhood

Intrauterine Growth Restriction | Cardiopulmonary Disease

Greece
Centervue SpA

Recruiting

Clinical Evaluation of Visual Field Change in Glaucoma: an Assessment of Different Models of Progression

Glaucoma

Italy
MMI Spa

Recruiting

PRIMO Post-Market Clinical Follow Up Study (PRIMO)

Open Surgery | Blood Vessels, Lymphatic Ducts and Nerves | Free Flaps

Spain, Switzerland, Italy, Belgium, Austria, Germany
Labomar SPA

Completed

Study for Evaluation of Probiotics in the Re-equilibration of the Intestinal Microbiota, in Paediatric Age

Diarrhea

Italy
Permedica spa

Completed

Total Knee Arthroplasty With Vitamin E Polyethylene

Knee Osteoarthritis

Italy
Zambon SpA

Active, not recruiting

Efficacy + Safety of Liposome Cyclosporine A to Treat Bronchiolitis Obliterans Post Single Lung Transplant (BOSTON-2) (BOSTON-2)

Bronchiolitis Obliterans | Lung Transplant Rejection | Lung Transplant; Complications | Lung Transplant Failure and Rejection | Chronic Rejection of Lung Transplant | Chronic Lung Allograft Dysfunction

France, United States, Spain, Israel, Belgium, Denmark, Germany, United Kingdom, Austria
SIFI SpA

Completed

Non-comparative Trial Following Participants Implanted Bilaterally With Mini WELL Toric Ready Intraocular Lens for 6 Months After the Second Eye Implant (FUSION) (FUSION)

Astigmatism | Bilateral Cataract

Spain, France, Germany
Zambon SpA

Completed

Phase 1 Three Part SAD, MAD & Cross-Over Study of ZP-059 in Healthy and Asthmatic Subjects

Allergic Bronchopulmonary Aspergillosis

United Kingdom
Algenis SpA

Completed

Gonyautoxin 2/3 in the Treatment of Acute Back Pain: A Clinical Proof-of-concept Study

Back Pain | Acute Pain

Chile
VISUfarma SpA

Unknown

Evaluate the Improving Effects of Visucomplex Plus on Quality of Life in Patients With AMD

AMD

Italy
Permedica spa

Terminated

Effectiveness of Titanium Niobium Nitride Coating in Total Knee Arthroplasty

Knee Arthritis
VISUfarma SpA

Completed

Evaluation of MAF-1217 in Patients With DED

Evaporative Dry Eye Disease

Italy
VISUfarma SpA

Completed

Evaluation of the VisuXL® Performance on Ocular Surface Discomfort

Ocular Discomfort

Italy
Ingalfarma SpA

Completed

Study of Dentoxol® Mouthrinse for Oral Mucositis

Oral Mucositis

Chile
Zambon SpA

Completed

Efficacy and Tolerability Study of ZP-025 Vaginal Gel for the Treatment of Vaginal Dryness

Vaginal Dryness

Italy
SIFI SpA

Completed

Safety and Tolerability of Preservative-free Polyhexamethylene Biguanide (PHMB) Ophthalmic Solution in Healthy Subjects

Acanthamoeba Keratitis
Permedica spa

Active, not recruiting

Follow-up Evaluating Clinical and Radiological Outcomes of Total Shoulder Arthroplasty With Permedica's MIRAI Prosthesis

Psoriatic Arthritis | Shoulder Osteoarthritis | Primary Osteoarthritis | Secondary Osteoarthritis | Avascular Necrosis of Humerus | Rheumatoid Arthritis Shoulder | Cuff Tear Arthropathy | Fracture, Shoulder

Germany, Italy, Switzerland
Zambon SpA

Terminated

Trial in Non-cystic Fibrosis Bronchiectasis Patients With Chronic Lung Infections Treated With Colistimethate Sodium. (PROMIS-II)

Non Cystic Fibrosis Bronchiectasis

United States, Argentina, Australia, Canada, France, Germany, Greece, Israel, Italy, New Zealand, Poland, Portugal
Zambon SpA

Completed

Efficacy and Safety of Inhaled CMS in Bronchiectasis Subjects With Chronic P. Aeruginosa Infection. (PROMIS-I) (PROMIS-I)

Non Cystic Fibrosis Bronchiectasis

Australia, Greece, Israel, Italy, Portugal, Belgium, Germany, Netherlands, New Zealand, Spain, Switzerland, United Kingdom
Zambon SpA

Active, not recruiting

Efficacy + Safety of Liposome Cyclosporine A to Treat Bronchiolitis Obliterans Post Single Lung Transplant (BOSTON-1) (BOSTON-1)

Bronchiolitis Obliterans | Lung Transplant Rejection | Lung Transplant; Complications | Lung Transplant Failure and Rejection | Chronic Rejection of Lung Transplant | Chronic Lung Allograft Dysfunction

France, United States, Spain, Israel, Belgium, United Kingdom, Germany
Zambon SpA

Completed

A Single and Multiple Dose Study to Assess How the Drug Enters, Moves Through and Exits the Body, Safety and Tolerability of Safinamide in Healthy Adult Chinese Volunteers

Healthy

China
SIFI SpA

Terminated

To Demonstrate the Non-inferiority of Eyestil Protection® Compared to Vismed® in Terms of Clinical Performance

Dry Eye Syndrome

Spain, France
Zambon SpA

Completed

A Clinical Study to Evaluate Z7200 (Budesonide/Formoterol) Pharmacokinetics Profile in Healthy Volunteers

Asthma

United Kingdom
Zambon SpA

Completed

Safinamide for Multiple System Atrophy (MSA)

Multiple System Atrophy

Italy, Spain
Cassiopea SpA

Completed

A Study to Evaluate the Safety and Efficacy of CB-03-01 Cream, 1% in Subjects With Facial Acne Vulgaris (25)

Acne Vulgaris

United States, Georgia, Ukraine
Cassiopea SpA

Completed

An Open-Label, Long-Term Extension Study to Evaluate the Safety of CB-03-01 Cream, 1% in Participants With Acne Vulgaris

Acne Vulgaris

United States, Bulgaria, Romania, Serbia, Georgia, Poland, Ukraine
VISUfarma SpA

Unknown

Valuation of the Antioxidant and Neuroprotective Effects of CoQ10-MINIACTIVES® (COQUN® OS) in Patients Affected by Primary Open Angle Glaucoma

Glaucoma, Open-Angle

Italy
VISUfarma SpA

Completed

Bioavailability Study of COQUN ORAL FORMULATION

Male & Female Healthy Volunteers

Romania
VISUfarma SpA

Completed

Evaluation of the Performance of MAF-1217 on Cataract Surgery

Dry Eye

Italy
Cassiopea SpA

Completed

A Study to Investigate the Effects of Cortexolone 17α-propionate (and Its Metabolites) on Healthy Volunteers' Heart

Healthy Volunteers

United Kingdom
SIFI SpA

Completed

Microbiological Evaluation of the Ocular Flora Before Cataract Surgery

Disorders of the Eye Following Cataract Surgery

Italy
Zambon SpA

Completed

Study of the Effects of High-dose N-acetylcysteine (NAC) in Idiopathic Pulmonary Fibrosis (IPF) (IFIGENIA)

Pulmonary Fibrosis

Spain, Germany, Belgium, France, Italy, Netherlands, United Kingdom
SIFI SpA

Completed

Efficacy of Topical 0.2% Xanthan Gum in Patients With Dry Eye

Dry Eye

Italy
MELISA Institute Genomics & Proteomics Research...
Universidad Austral

Unknown

Previfenon® as Chemoprophylaxis of COVID-19 in Health Workers (HERD)

COVID-19 | SARS-CoV2
PromoPharma spa

Recruiting

Interventistic Clinical Investigation on the Use of Medical Device in Subjects With Mild-moderate Osteoarticular Pain

Osteoarthritis, Knee

Italy
Permedica spa

Not yet recruiting

Bone Remodeling Around a Trabecular Titanium Cup in Total Hip Arthroplasty

Total Hip Arthroplasty

Italy
SIFI SpA

Recruiting

Observational Prospective Clinical Investigation on Monofocal Toric Intraocular Lens

Cataract | Astigmatism

Romania
SIFI SpA

Recruiting

Observational, Prospective Clinical Investigation on Mini 4 Ready Intraocular Lens

Cataract

Italy
Zambon SpA

Completed

A Study to Evaluate the Efficacy and Safety of Safinamide, as add-on Therapy, in Idiopathic Chinese Parkinson's Disease (PD) Patients With Motor Fluctuations Treated With Stable Doses of Levodopa

Parkinson Disease

China
Centervue SpA

Active, not recruiting

Clinical Investigation of a New Version of MAIA Microperimeter on Healthy Subjects and Patients With Retinal Pathology

Retinal Diseases | Healthy Eyes

Switzerland

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