Clinical Trials Sponsored by Fraunhofer Institut für Arbeitswirtschaft und Organisation

Total 156 results

Technische Universität Dresden
Fraunhofer Institute for Ceramic Technologies and Systems IKTS

Completed

Computer-aided Diagnosis of Ocular Diseases Based on Corneal Biomechanics (EyeTwin)

Glaucoma | Corneal Astigmatism | Keratoconus | Open Angle Glaucoma | Corneal Ectasia | Corneal Disease | Normal Tension Glaucoma

Germany
Fraunhofer-Institute of Toxicology and Experimental...
Institute for Pharmacology and Toxicology, RWTH Aachen

Completed

Demonstration of Broncholytic Effects in Subjects With Obstructive Airway Diseases by Low Frequency Ultrasound (Pabes)

Healthy Volunteers | COPD GOLD I to IV | Asthma GINA 1 to 4

Germany
Dr. Frank Behrens
Pfizer

Recruiting

Capability of Tofacitinib or Etanercept to Accelerate Tapering of NSAID and Treat-to-target Guided De-escalation of Corticosteroids in RA Patients (AcceleRAte)

Rheumatic Arthritis

Germany
Gerd Geisslinger
Fraunhofer Institute for Molecular Biology and Applied Ecology

Completed

Bioavailability, Pharmacokinetics and Tissue Distribution of R-flurbiprofen Capsules in Healthy Subjects

Healthy Volunteers

Germany
Jena University Hospital
Fraunhofer Institute for Cell Therapy and Immunology, Leipzig, Germany

Unknown

NExt-Generation Sequencing and Cell Culture-based Characterization of S. Aureus in Infective Endocarditis (NESSIE)

Infective Endocarditis | Infection Staphylococcal

Germany
Dr. Frank Behrens
Bionorica SE

Recruiting

Effect of Bronchipret on Antiviral Immune Response in Patients With Mild COVID-19 (BroVID)

COVID-19

Germany
Dr. Frank Behrens
Bionorica SE

Active, not recruiting

Impact of Silymarin Dosages to Decrease Drug-induced Elevated Liver Enzymes Compared to Placebo (SILVER)

Drug-induced Liver Injury

Germany
Fraunhofer Institute for Molecular Biology and...
Bristol-Myers Squibb; Goethe University

Completed

PREVALENCE OF Anti-CCP POSITIVITY AND SUBCLINICAL SIGNS OF INFLAMMATION IN PATIENTS WITH NEW ONSET OF NON-SPECIFIC MUSCULOSKELETAL SYMPTOMS (PANORA)

Rheumatoid Arthritis

Germany
Dr. Frank Behrens
SocraMetrics GmbH

Completed

TMP001 in Relapsing-remitting Multiple Sclerosis

Remitting-Relapsing Multiple Sclerosis

Germany
Fraunhofer-Institute of Toxicology and Experimental...
Federal Institute for Occupational Safety and Health (BAuA)/Germany)

Completed

Pharmacokinetics of Enrofloxacin in Plasma and Urine (EnroHuman)

Healthy

Germany
Medical University of Graz
University of Leeds; Catholic University of the Sacred Heart; University of Manchester and other collaborators

Not yet recruiting

Kidney AI-enabled Care Transformation

Chronic Kidney Diseases

United Kingdom, Italy
Dr. Frank Behrens
Janssen-Cilag Ltd.

Completed

Impact of Concomitant MTX on Efficacy, Safety and Adherence of Ustekinumab-treatment in Patients With Active PsA (MUST)

Psoriatic Arthritis

Germany
University Hospital Heidelberg
Fraunhofer Institute for Interfacial Engineering and Biotechnology; Dietmar...

Completed

Next-Generation Sequencing Diagnostics of Bacteremia in Sepsis (NextGeneSiS)

Sepsis | Septic Shock

Germany
Leibniz-Institut für Resilienzforschung (LIR) gGmbH
European Regional Development Fund; Ministry of Science and Health of Rhineland-Palatinate... and other collaborators

Recruiting

"resiLIR Healthcare Professionals": A Psychological Online Intervention to Enhance Resilience in Healthcare Professionals

Resilience

Germany
Leibniz-Institut für Resilienzforschung (LIR) gGmbH
European Regional Development Fund; Ministry of Science and Health of Rhineland-Palatinate... and other collaborators

Recruiting

"resiLIR Basic": A Psychological Online Intervention to Enhance Resilience in the General Population

Resilience

Germany
Dr. Frank Behrens
Johann Wolfgang Goethe University Hospital

Recruiting

Prevention of Paclitaxel-induced Neuropathic Pain in Patients With Planned Paclitaxel Chemotherapy (PrevTel) (PrevTel)

Neuropathic Pain | Chemotherapy Effect

Germany
Hadassah Medical Organization
University of Erlangen-Nürnberg Medical School; Institut für Klinische und...

Completed

Artesunate in Preemptive Treatment of Human Cytomegalovirus (CMV) in Stem Cell Transplant Recipients

Cytomegalovirus Infections

Israel
Dr. Frank Behrens
Celgene; Dermatology Department University Hospital Frankfurt

Completed

Preliminary Efficacy and Safety of Apremilast in the Treatment of Acne Conglobata (APACCO)

Acne Conglobata

Germany
Maastricht University
Top Institute Food and Nutrition; Netherlands Organisation for Scientific Research

Completed

Mitochondria and Muscle Health in Elderly (ELMIH)

Muscle Weakness

Netherlands
University College Dublin
University of Padova; Institut National de Recherche pour l'Agriculture, l'Alimentation... and other collaborators

Completed

Determination of In-vivo Plasma AA Appearance From Plant Protein Fibre Products

Aging | Undernutrition | Appetite Loss | Age-Related Sarcopenia

Ireland, Italy
Reade Rheumatology Research Institute
ZonMw: The Netherlands Organisation for Health Research and Development

Recruiting

Use of Tocilizumab Drug Levels to Optimize Treatment in RA (TODORA)

Rheumatoid Arthritis

Netherlands
European Organisation for Research and Treatment...

Unknown

High-Dose or Low-Dose Interferon Alfa Compared With No Further Therapy Following Surgery in Treating Patients With Stage III Melanoma

Melanoma (Skin)

France, Switzerland, Netherlands, Poland, Finland, Belgium, United Kingdom, Austria, Germany, Italy, Israel, Slovakia, Spain, Serbia, Portugal, Russian Federation, Bulgaria, Croatia, Turkey, Estonia, Sweden
European Organisation for Research and Treatment...

Unknown

Combination Chemotherapy Plus Steroid Therapy in Treating Children With Acute Lymphoblastic Leukemia or Lymphoblastic Non-Hodgkin's Lymphoma

Lymphoma | Leukemia

France, Belgium, Portugal
European Organisation for Research and Treatment...

Completed

Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome

Myelodysplastic Syndromes | Leukemia

France, Belgium, Portugal
European Organisation for Research and Treatment...

Unknown

Amifostine With or Without Epoetin Alfa in Treating Patients With Myelodysplastic Syndrome

Myelodysplastic Syndromes | Anemia

Belgium, Switzerland, Czech Republic, Portugal, Austria, Netherlands, Slovakia
European Organisation for Research and Treatment...

Unknown

Combination Chemotherapy With or Without Idarubicin and Peripheral Stem Cell Transplantation in Treating Patients With Leukemia or Myelodysplastic Syndrome

Lymphoma | Myelodysplastic Syndromes | Leukemia | Multiple Myeloma and Plasma Cell Neoplasm

France, Belgium, Netherlands, Germany, Italy
The Netherlands Cancer Institute
ZonMw: The Netherlands Organisation for Health Research and Development

Recruiting

Dedicated MR Imaging vs Surgical Staging of Peritoneal Carcinomatosis in Colorectal Cancer (DISCO)

MRI | Colorectal Cancer | Peritoneal Carcinomatosis

Netherlands
European Organisation for Research and Treatment...

Unknown

Study of Long-Term Outcomes of Patients With Acute Lymphoblastic Leukemia Who Were Enrolled as Children on Clinical Trials EORTC-58741, EORTC-58831, EORTC-58832, or EORTC-58881 Between 1971 and 1998

Leukemia | Cancer Survivor | Long-term Effects Secondary to Cancer Therapy in Children
European Organisation for Research and Treatment...

Unknown

Cetuximab, Leucovorin, Oxaliplatin, and Fluorouracil With or Without Bevacizumab in Treating Patients With Resectable Liver Metastases From Colorectal Cancer

Colorectal Cancer | Metastatic Cancer

France
European Organisation for Research and Treatment...

Unknown

Low-Dose Decitabine Compared With Standard Supportive Care in Treating Older Patients With Myelodysplastic Syndrome

Myelodysplastic Syndromes | Leukemia | Myelodysplastic/Myeloproliferative Neoplasms

Belgium, Netherlands, Germany, Italy, United Kingdom, Austria, Czech Republic, Croatia, Turkey, Switzerland
European Organisation for Research and Treatment...

Unknown

Vaccine Therapy in Treating Patients With Primary Stage II Melanoma

Melanoma (Skin)

Italy, France, Spain, Switzerland, United Kingdom, Belgium, Australia, Norway, Poland, Finland, Netherlands, Germany, Israel, Denmark, Serbia, Estonia, Portugal, Russian Federation
European Organisation for Research and Treatment...
Northwell Health Cancer Institute

Not yet recruiting

Adjuvant Tebentafusp in High Risk Ocular Melanoma (ATOM)

Uveal Melanoma
European Organisation for Research and Treatment...

Unknown

Combination Chemotherapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Myelodysplastic Syndrome or Acute Myelogenous Leukemia

Myelodysplastic Syndromes | Leukemia

Switzerland, Netherlands, France, Belgium, Germany, Sweden, Croatia, Czech Republic, Italy
European Organisation for Research and Treatment...

Unknown

Lymph Node Radiation Therapy in Patients With Stage I, Stage II, or Stage III Breast Cancer That Has Been Surgically Removed

Breast Cancer

France, Switzerland, Netherlands, Belgium, Italy, Israel, Germany, United Kingdom, Portugal, Spain, Chile, Poland, Turkey, Bosnia and Herzegovina
European Organisation for Research and Treatment...

Unknown

Combination Chemotherapy Followed by Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Acute Myelogenous Leukemia

Leukemia

France, Belgium, Netherlands, Italy, Czech Republic, Portugal, Germany, Croatia, Turkey, Austria, Hungary
European Organisation for Research and Treatment...

Unknown

Combination Chemotherapy in Treating Patients With Relapsed Acute Myelogenous Leukemia

Leukemia

Belgium, France, Netherlands, Portugal, Italy, Croatia, Turkey
European Organisation for Research and Treatment...

Unknown

Chlorambucil in Treating Patients With Advanced Chronic Lymphocytic Leukemia

Leukemia

Belgium, Netherlands, Czech Republic, Hungary, Italy, Macedonia, The Former Yugoslav Republic of, Portugal
DBL -Institute for Health Research and Development
World Health Organization; Institute for Epidemiology and Social Medicine,...

Terminated

Acceptability and Cost Effectiveness of Home Based Management of Fever: Different Strategies

Fever | Malaria | Anaemia

Uganda
National Institute for Public Health and the Environment...
ZonMw: The Netherlands Organisation for Health Research and Development

Unknown

A Randomised Controlled Trial on the Effect of Post-exposure Oseltamivir Prophylaxis on Influenza Transmission in Nursing Homes (PEPpIE)

Influenza

Netherlands
Vall d'Hebron Institute of Oncology
European Organisation for Research and Treatment of Cancer - EORTC

Terminated

Study With Atezolizumab Plus Bevacizumab in Patients With Chemotherapy Resistant, MSI-like, Colorectal Cancer

Chemotherapy | ColoRectal Cancer | MSI | Resistance, APC

Belgium, Netherlands, Spain, Italy
Erasmus Medical Center
National Institute for Public Health and the Environment (RIVM); Netherlands...

Recruiting

Shift Work Intervention Strategies for Night Shift Workers (GRIP)

Shift-Work Related Sleep Disturbance

Netherlands
European Organisation for Research and Treatment...
Institute of Cancer Research, United Kingdom; Arbeitsgruppe Lebermetastasen...

Terminated

Chemotherapy and Bevacizumab With or Without Radiofrequency Ablation in Treating Unresectable Liver Metastases in Patients With Colorectal Cancer

Colorectal Cancer | Metastatic Cancer

Netherlands, United Kingdom, Belgium, France, Germany, Sweden, Hungary, Austria, Egypt, Italy
Maastricht University
Wageningen University and Research; Top Institute Food and Nutrition; Netherlands...

Terminated

The Effect of Fish Oils With Dairy or Plant Based Lipids on Mitochondrial and Physical, and Cognitive Function, in Elderly Humans

Cognitive Function | Ageing | Physical Function | Mitochondrial Function

Netherlands
Pan American Health Organization
Centers for Disease Control and Prevention; World Health Organization; Institute...

Completed

Study of Inactivated Poliovirus Vaccine Given at an Earlier Schedule With Shorter Intervals

Level of Immunity Against Poliovirus Infection
Dr. Frank Behrens
University Hospital Frankfurt, Department of Anaesthesiology; IRON4U; University...

Recruiting

Postoperative i.v. Iron Substitution in Patients With Diagnosed Iron Deficiency (IDA-II)

Iron Deficiency Anemia

Germany
Dr. Frank Behrens
University Hospital Frankfurt, Department of Anaesthesiology; IRON4U; University...

Suspended

Polyglucoferron Compared to i.v. Ferric Carboxymaltose and Oral Iron Substitution in Preoperative Treatment of Iron Deficiency Anaemia in Patients (IDA-I)

Iron Deficiency Anemia

Germany
Reade Rheumatology Research Institute
ZonMw: The Netherlands Organisation for Health Research and Development; Sint...

Completed

Adalimumab Dose Reduction Aiming Low Serum Concentration With Control of Disease Activity (ADDORA-low)

Rheumatoid Arthritis

Netherlands
Pauline Verdijk
World Health Organization

Completed

Safety and Immunogenicity of a New Inactivated Polio Vaccine in Healthy Adults

Poliomyelitis

Poland
Reade Rheumatology Research Institute
ZonMw: The Netherlands Organisation for Health Research and Development; Sint...

Recruiting

Adalimumab Drug Optimisation in Rheumatoid Arthritis Using Therapeutic Drug Monitoring (ADDORA)

Rheumatoid Arthritis

Netherlands
Reade Rheumatology Research Institute
ZonMw: The Netherlands Organisation for Health Research and Development; Sint...

Active, not recruiting

Using Adalimumab Serum Concentration to Choose a Subsequent Biological DMARD in Rheumatoid Arthritis Patients Failing Adalimumab Treatment (ADDORA-switch)

Rheumatoid Arthritis

Netherlands

Clinical Trials Sponsored by Fraunhofer Institut für Arbeitswirtschaft und Organisation

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