Clinical Trials Sponsored by Fraunhofer Institute

Total 74462 results

Fraunhofer-Institute of Toxicology and Experimental...

Completed

Quantification of Exhaled Particles to Identify Airborne Transmission Risks of COVID-19 (QUELLE)

Healthy

Germany
Fraunhofer-Institute of Toxicology and Experimental...

Completed

Characterization of the Inhibitory Effects of Fevipiprant (QAW039) on Activation of Eosinophils and ILC2 Cells by Prostaglandin D2 Metabolites (18-03 EONOV)

Atopic Asthma

Germany
Fraunhofer-Institute of Toxicology and Experimental...

Completed

The Role of Pollen Starch Granules in Pollen Challenge Studies in the Fraunhofer Environmental Exposure Unit

Asthma | Seasonal Allergic Rhinitis

Germany
Fraunhofer-Institute of Toxicology and Experimental...

Completed

Study to Compare the Effect of a Combination of Cetirizine With Pseudoephedrine Versus Placebo on Symptoms in Patients With Allergic Rhinitis Within/Out of Season

Rhinitis | Atopy

Germany
Fraunhofer-Institute of Toxicology and Experimental...

Terminated

Effect of an Immunotoxin on Activated Human Macrophages in Those With Allergic Rhinitis or Mild Intermittent Asthma

Rhinitis | Bronchial Asthma | Atopy

Germany
Fraunhofer-Institute of Toxicology and Experimental...

Completed

A Pilot Monocenter Study to Assess Cellular and Soluble Biomarkers in Nasal Secretions

Healthy Subjects | Seasonal Allergic Rhinitis

Germany
Fraunhofer-Institute of Toxicology and Experimental...

Completed

Second Follow-up Study of COPD Patients and Healthy Controls for Evaluation of Predictive Non-coding RNA Biomarkers (Ribo III)

Chronic Obstructive Pulmonary Disease

Germany
Fraunhofer-Institute of Toxicology and Experimental...

Completed

Impact of Carrier Solutions for House Dust Mite Allergen on Allergic Reactions (SIMBA)

Allergic Rhinitis

Germany
Fraunhofer-Institute of Toxicology and Experimental...

Completed

Investigation of Secreted Phosphoproteins and PiP3 (Phosphoinositolphospat 3) in Sputum

Healthy | Smoking, Cigarette

Germany
Fraunhofer-Institute of Toxicology and Experimental...

Completed

Monocenter 6-period Study in Patients With Seasonal Allergic Rhinitis to Birch Pollen to Establish a Challenge Model With Natural Birch Pollen in an Environmental Challenge Chamber (ECC)

Seasonal Allergic Rhinitis
Fraunhofer-Institute of Toxicology and Experimental...

Completed

Validation of an Environmental Exposure Chamber for Inhalation Studies With House Dust Mite Allergen in Patients With Allergic Rhinitis

Allergy to House Dust Mite

Germany
Fraunhofer-Institute of Toxicology and Experimental...

Completed

Novel Noninvasive Techniques to Study Neutrophil Airway Inflammation in an Ozone Challenge Model

Healthy Subjects

Germany
Technical University of Munich
Fraunhofer Institut Erlangen

Unknown

Computer-assisted Detection of Colonic Polyps (KoloPol I)

Colon Adenoma

Germany
Fraunhofer-Institute of Toxicology and Experimental...

Recruiting

Development of a Novel Non-invasive Inflammometry Following Allergen Challenge in Patients With Mild Allergic Asthma

Mild Allergic Asthma

Germany
Fraunhofer-Institute of Toxicology and Experimental...

Recruiting

Biosensor and Environmental Sensor Development Within the REMEDIA Project

Healthy | Chronic Obstructive Pulmonary Disease

Germany
Fraunhofer-Institute of Toxicology and Experimental...

Recruiting

Threshold Concentrations for Ragweed and Birch Pollen in Seasonal Allergic Rhinitis (UBAMBI)

Allergic Rhinitis | Seasonal Allergic Rhinitis | Birch Pollen Allergy | Ragweed Allergy

Germany
Fraunhofer-Institute of Toxicology and Experimental...

Completed

Characterization of Aerosol Generation and Transport in the Human Lung of Subjects With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

Germany
Fraunhofer-Institute of Toxicology and Experimental...

Completed

Follow-up-study of COPD Patients and Healthy Controls for Evaluation of Predictive Non-coding RNA Biomarkers (Ribo2)

Chronic Obstructive Pulmonary Disease

Germany
Fraunhofer-Institute of Toxicology and Experimental...

Completed

Suitability of a Low Dose Lipopolysaccharide (LPS) Inhalation as a Challenge Model

Healthy

Germany
Fraunhofer-Institute of Toxicology and Experimental...

Completed

Characterization of Aerosol Generation and Transport in the Human Lung

Asthma
Fraunhofer-Institute of Toxicology and Experimental...
GlaxoSmithKline

Completed

Study to Assess the Effect of a Combination of Cetirizine With Pseudoephedrine Versus Cetirizine Alone on Symptoms in Patients With Allergic Rhinitis

Seasonal Allergic Rhinitis

Germany
Fraunhofer, Center for Molecular Biotechnology

Completed

Safety and Immunogenicity Of A Recombinant H5N1 Vaccine In Adults

Healthy

United States
Fraunhofer, Center for Molecular Biotechnology

Completed

PA83-FhCMB Plant-Derived Recombinant Protective Antigen (rPA) Anthrax Vaccine

Anthrax

United States
Fraunhofer-Institute of Toxicology and Experimental...
AstraZeneca

Completed

Use of Exhaled Particles to Assess Lung Pharmacokinetics (EXPLORE)

Healthy | Lung Pharmacokinetic

Germany
Fraunhofer-Institute of Toxicology and Experimental...
AstraZeneca

Completed

Lung Pharmacokinetics (PK) in Epithelial Lining Fluid (ELF)

Healthy

Germany
Fraunhofer, Center for Molecular Biotechnology

Completed

Safety and Immunogenicity of Plant-Derived Pfs25 VLP-FhCMB Malaria Transmission Blocking Vaccine in Healthy Adults

Malaria

United States
Boston Medical Center
Fraunhofer USA

Completed

Use of an In Vivo Optical Probe to Discriminate Benign From Malignant Thyroid Nodules

Cancer | Thyroid

United States
Fraunhofer-Institute of Toxicology and Experimental...
Boehringer Ingelheim

Completed

Effects of Spiolto® Respimat® (Tiotropium/Olodaterol) on Cardiac Function in Hyperinflated COPD Subjects

Chronic Obstructive Pulmonary Disease

Germany
Fraunhofer-Institute of Toxicology and Experimental...
UCB Pharma

Completed

Evaluation of Nasal Inflammatory Biomarkers

Seasonal Allergic Rhinitis

Germany
Fraunhofer-Institute of Toxicology and Experimental...
Hannover Medical School

Completed

Skin Responses and T Cell Immunology After House Dust Mite Exposure in Sensitized Atopic Dermatitis Patients (CODES)

Atopic Dermatitis | House Dust Mite Allergy

Germany
Fraunhofer-Institute of Toxicology and Experimental...
Hannover Medical School

Completed

Study to Assess the Effect of "Eucerin AtopiControl" on Dermal Symptoms in Patients With Atopic Dermatitis

Atopic Dermatitis | Allergy Pollen

Germany
Fraunhofer-Institute of Toxicology and Experimental...
Hannover Medical School

Completed

Effect of Pollen Challenges on Dermal Symptoms in Patients With Atopic Dermatitis (Neurop)

Atopic Dermatitis
Fraunhofer-Institute of Toxicology and Experimental...
German Research Foundation

Completed

Influence of Diesel Exhaust Particles (DEP) With and Without Organic Compounds on the Allergic Inflammation in Asthmatic Subjects

Asthma

Germany
Fraunhofer-Institute of Toxicology and Experimental...
Hannover Medical School

Completed

Development of Novel Non-invasive Inflammometry Following Lipopolysaccharide, Endotoxin (LPS) Challenge in Healthy Volunteers

Healthy

Germany
Hannover Medical School
Fraunhofer-Institute of Toxicology and Experimental Medicine

Unknown

Experimental Exposure to Air Pollutants and Sympathetic Nerve Activity in Human Subjects (Particles)

Cardiovascular Morbidity

Germany
Fraunhofer-Institute of Toxicology and Experimental...
Hannover Medical School

Completed

Pilot Study for Cell Based Therapies in Patients With Asthma

Asthma | Allergic Rhinitis
Fraunhofer-Institute of Toxicology and Experimental...
German Research Foundation

Completed

Study to Explore the Effects of Two Hour Inhalation of Ultrafine Carbon Black Particles on Airway Inflammation in Asthmatics

Asthma

Germany
Fraunhofer-Institute of Toxicology and Experimental...
Hannover Medical School

Completed

Ex Vivo Effect of Surfactant Protein D on Pulmonary Cells in Patients With Asthma and Pilot Study to Assess Local Inflammation Induced by Segmental Allergen Challenge by Magnetic Resonance Imaging

Mild Intermittent Asthma (Gina 1)

Germany
Fraunhofer-Institute of Toxicology and Experimental...
German Research Foundation

Completed

Ex Vivo Effect of Surfactant Protein D on Pulmonary Immune Cells Derived From Bronchoalveolar Lavage After Segmental Allergen Challenge in Patients With Asthma

Asthma

Germany
Prof. Dr. Jens Hohlfeld

Completed

Activation of Apoptosis-related Receptors on Alveolar Macrophages

Chronic Obstructive Pulmonary Disease

Germany
University of Rostock
German Center for Neurodegenerative Diseases (DZNE); Fraunhofer Institute

Completed

SAMi Intervention Study to Evaluate Smartwatch Interventions in Persons With MCI and Dementia (SAIN_UMR)

Dementia | Alzheimer Disease | Mild Cognitive Impairment | Dementia, Vascular | Dementia, Mixed | Dementia With Lewy Bodies | Dementia Frontotemporal

Germany
RWTH Aachen University
Philips Healthcare; MUL Services GmbH; Fraunhofer Institute (IMS)

Completed

MeDiNa Pilot Study for Evaluation of the MeDiNa Concept of Homely Rehabilitation After Myocardial Infarction

Feasibility of Telemedical Home Monitoring | Post Stationary | Patients With Myocardial Infarction

Germany
Technische Universität Dresden
Fraunhofer Institute for Ceramic Technologies and Systems IKTS

Completed

Computer-aided Diagnosis of Ocular Diseases Based on Corneal Biomechanics (EyeTwin)

Glaucoma | Corneal Astigmatism | Keratoconus | Open Angle Glaucoma | Corneal Ectasia | Corneal Disease | Normal Tension Glaucoma

Germany
Fraunhofer-Institute of Toxicology and Experimental...
Institute for Pharmacology and Toxicology, RWTH Aachen

Completed

Demonstration of Broncholytic Effects in Subjects With Obstructive Airway Diseases by Low Frequency Ultrasound (Pabes)

Healthy Volunteers | COPD GOLD I to IV | Asthma GINA 1 to 4

Germany
MEDIGREIF Inselklinik Heringsdorf
Fraunhofer Institut für Graphische Datenverarbeitung (IGD), Rostock, Germany

Completed

Electronic Health Technology for Assessment of Physical Activity and Eating Habits in Children and Adolescents Who Are Overweight and Those With Obesity

Obesity | Overweight

Germany
Dr. Frank Behrens
Pfizer

Recruiting

Capability of Tofacitinib or Etanercept to Accelerate Tapering of NSAID and Treat-to-target Guided De-escalation of Corticosteroids in RA Patients (AcceleRAte)

Rheumatic Arthritis

Germany
Gerd Geisslinger
Fraunhofer Institute for Molecular Biology and Applied Ecology

Completed

Bioavailability, Pharmacokinetics and Tissue Distribution of R-flurbiprofen Capsules in Healthy Subjects

Healthy Volunteers

Germany
Jena University Hospital
Fraunhofer Institute for Cell Therapy and Immunology, Leipzig, Germany

Unknown

NExt-Generation Sequencing and Cell Culture-based Characterization of S. Aureus in Infective Endocarditis (NESSIE)

Infective Endocarditis | Infection Staphylococcal

Germany
Fraunhofer-Institute of Toxicology and Experimental...
M et P Pharma AG

Completed

Effect of the Nasal Gel "Nascum®-Plus" on Allergic Symptoms (NAPO)

Rhinitis, Allergic, Seasonal

Germany
Dr. Frank Behrens
Bionorica SE

Recruiting

Effect of Bronchipret on Antiviral Immune Response in Patients With Mild COVID-19 (BroVID)

COVID-19

Germany

Clinical Trials Sponsored by Fraunhofer Institute

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