Clinical Trials Sponsored by Genescient Corporation

Total 6509 results

Incyte Corporation

Completed

Arginase Inhibitor INCB001158 as a Single Agent and in Combination With Immune Checkpoint Therapy in Patients With Advanced/Metastatic Solid Tumors

Head and Neck Cancer | Gastric Cancer | Lung Cancer | Metastatic Cancer | Mesothelioma | Bladder Cancer | Solid Tumors | Renal Cell Carcinoma (RCC) | Colorectal Cancer (CRC) | UC (Urothelial Cancer)

Italy, Spain, United States, Netherlands
Incyte Corporation

Terminated

Safety and Efficacy of Itacitinib in Combination With Corticosteroids for Treatment of Graft-Versus-Host Disease in Pediatric Subjects

Acute Graft-versus-host Disease

United States, Spain, France, Italy, United Kingdom, Germany
Incyte Corporation

Approved for marketing

Expanded Access of Ruxolitinib Cream to Treat a Single Patient With cGVHD

Graft-versus-host Disease (GVHD)
Yuhan Corporation

Completed

A FIH Study of YH35324 in Atopic Healthy Subjects or Subjects With Mild Allergic Diseases

Atopic Healthy Subjects | Adult Subjects With Mild Allergic Diseases

Korea, Republic of
Oxfo Corporation

Completed

Sustainable Preservation of Essential Oxygen Resources: A Phase 4 Crossover Study of the BUFEO System: SAVE O2 (SAVEO2)

Oxygen Deficiency | Oxygen Therapy

Colombia
Genelux Corporation

Completed

GL-ONC1 Oncolytic Immunotherapy in Patients With Recurrent or Refractory Ovarian Cancer

Ovarian Cancer | Fallopian Tube Cancer | Peritoneal Carcinomatosis

United States
Caerus Corporation

Enrolling by invitation

Study to Evaluate the OrthoCor Active System for Pain Relief

Pain

United States
Mannkind Corporation

Completed

Afrezza With Basal Combination (ABC)

Type 1 Diabetes

United States
Allievex Corporation

Active, not recruiting

A Prospective Natural History Study of Mucopolysaccharidosis Type IIIB (MPS IIIB)

Mucopolysaccharidosis Type IIIB

United States, Germany, Spain, Argentina, Australia, Brazil, Colombia, Taiwan, Turkey
Masimo Corporation

Completed

Oxygen Reserve Index (ORi) Expanded Data Set Validation of INVSENSOR00025

Healthy

United States
Yuhan Corporation

Completed

Multi-center, Prospective, Cohort Study to Evaluate the Relationship of Stroke Recurrence and Anti-platelet Resistance in Ischemic Stroke Patients

Ischemic Stroke

Korea, Republic of
Incyte Corporation

Completed

A Placebo-Controlled Study of the Safety of INCB054707 in Participants With Hidradenitis Suppurativa

Hidradenitis Suppurativa

Canada, Denmark, Germany
Incyte Corporation

Completed

Topical Ruxolitinib Evaluation in Vitiligo Study 2 (TRuE-V2)

Non-segmental Vitiligo

United States, Canada, Italy, France, Germany, Spain, Poland, Bulgaria, Netherlands
Glaukos Corporation

Completed

Two Trabecular Micro-bypass Stents & Postoperative Travoprost to Treat Glaucoma Subjects on Two Hypotensive Agents

Open-angle Glaucoma

Armenia
Glaukos Corporation

Completed

Open-Angle Glaucoma Subjects With One Prior Trabeculectomy Treated Concurrently With One Suprachoroidal Stent and Two Trabecular Micro-bypass Stents

Open-Angle Glaucoma

Armenia
Glaukos Corporation

Completed

Purpose of This Study is to Evaluate the Safety and Efficacy of One, Two, or Three iStents for the Reduction of Intraocular Pressure in Open-angle Glaucoma Subjects

Primary Open Angle Glaucoma (POAG)

Armenia
Zxerex Corporation

Completed

Non-intrusive Detection of Temporary Neurologic Impairment by Opioids

Neurologic Impairment by Opioids

United States
Topcon Corporation

Completed

Clinical Study of the Topcon Pachymeter TRK-3 to Evaluate Agreement and Precision

Corneal Thickness

Japan
Topcon Corporation

Completed

Clinical Study of the Topcon Tonometer TRK-3

Intraocular Pressure

Japan
Masimo Corporation

Terminated

Utility of Non-invasive Carboxyhemoglobin and Total Hemoglobin Measurement in the Emergency Department

Anemia | Carbon Monoxide Poisoning

Turkey
Incyte Corporation

Completed

INCB050465 in Combination With Rituximab, Bendamustine and Rituximab, or Ibrutinib in Participants With Previously Treated B-Cell Lymphoma (CITADEL-112)

B-cell Lymphoma

United States, Spain, Italy
Incyte Corporation

Completed

A Study Assessing the Mass Balance, Pharmacokinetics, and Metabolite Profiles of a Single Oral Dose of [14C]-INCB086550

Healthy Volunteers

United Kingdom
Incyte Corporation

Completed

A Study of Itacitinib in Combination With Low-Dose Ruxolitinib or Itacitinib Alone Following Ruxolitinib in Participants With Myelofibrosis

MPN (Myeloproliferative Neoplasms)

United States, Netherlands, Austria
Irrimax Corporation

Terminated

Irrisept Versus Standard of Care in the Prevention of Surgical Site Infections

Surgical Site Infection

United States
Glaukos Corporation

Completed

Multicenter Study Using Glaukos® Trabecular Micro-Bypass Stent Model GTS400 Using the G2-M-IS Injector System in Conjunction With Cataract Surgery

Primary Open-angle Glaucoma

United States
Masimo Corporation

Completed

Comparison of Depth of Sedation Performance Between SedLine and Comparator Device During General Anesthesia

Anesthesia

United States
Masimo Corporation

Terminated

SedLine Engineering Data Collection Study in Pediatric Patients Undergoing General Anesthesia or Sedation

Anesthesia

United States
Incyte Corporation

Completed

Pembrolizumab Combined With Itacitinib (INCB039110) and/or Pembrolizumab Combined With INCB050465 in Advanced Solid Tumors

Melanoma | Breast Cancer | Head and Neck Cancer | Pancreatic Cancer | Lung Cancer | Endometrial Cancer | Solid Tumors | Renal Cell Carcinoma (RCC) | Colorectal Cancer (CRC) | UC (Urothelial Cancer) | MMR-deficient Tumors

United States
Candela Corporation

Completed

The CO2RE® System for Vulvar Lichen Sclerosus

Vulvar Lichen Sclerosus

United States
Erchonia Corporation

Completed

Study of Low Level Laser Therapy to Treat Diabetic Peripheral Neuropathy Foot Pain

Diabetic Peripheral Neuropathy

United States, Ireland
Yuhan Corporation

Approved for marketing

Early Access Program of Lazertinib in Republic of Korea

Lung Cancer
Yuhan Corporation

Completed

Clinical Trial to Assess Bioequivalence of Lazertinib Between Two Formulations in Healthy Volunteers.

Healthy Adult Volunteers

Korea, Republic of
Cerus Corporation

Completed

A Open Label, Post Marketing Surveillance Study Following Transfusion of INTERCEPT Platelet Components (PIPER)

Transfusion Related Acute Lung Injury

United States
Incyte Corporation

Completed

A Study of Ruxolitinib Phosphate Cream When Applied to Patients With Plaque Psoriasis

Psoriasis

United States
Irrimax Corporation

Terminated

The Effect of Wound Irrigation With Irrisept on Abscess Healing (Irrisept UF Study)

Abscess

United States
FA Corporation

Completed

Evaluation of the UltraClear Laser Workstation for Skin Treatment - Histology Study of Laser Ablation on Human Skin

Healthy

United States
Incyte Corporation

Terminated

Assessment of Efficacy and Safety of Ruxolitinib in Participants With COVID-19-Associated ARDS Who Require Mechanical Ventilation (RUXCOVID-DEVENT)

COVID-19

United States, Russian Federation
Yuhan Corporation

Terminated

A Clinical Trial of YH1177 in Patients With Otitis Media and Otorrhea

Otitis Media | Otorrhea

Korea, Republic of
Yuhan Corporation

Terminated

A Trial to Evaluate the Efficacy and Safety of YH12852 in Patients With Functional Dyspepsia

Functional Dyspepsia

Korea, Republic of
Incyte Corporation

Completed

Open-Label, Dose-Escalation Study of Pemigatinib in Subjects With Advanced Malignancies - (FIGHT-101)

Breast Cancer | Multiple Myeloma | Gastric Cancer | Lung Cancer | Solid Tumor | Cholangiocarcinoma | Endometrial Cancer | Urothelial Cancer | Myeloproliferative Neoplasms | UC | MPN

United States, Denmark
Masimo Corporation

Terminated

INVSENSOR00011 Clinical Performance Study

Healthy

United States
Incyte Corporation

No longer available

Expanded Access Program of Ruxolitinib for the Emergency Treatment of Cytokine Storm From COVID-19 Infection

COVID-19
Incyte Corporation

Terminated

Study of INCB053914 in Subjects With Advanced Malignancies

Solid Tumors

United States
Incyte Corporation

Completed

Study Evaluating Safety and Efficacy of INCB050465 Combined With Bendamustine and Obinutuzumab in Relapsed or Refractory Follicular Lymphoma (CITADEL-102)

Lymphoma

Spain, Hungary, United States, Denmark, Italy, Czechia
Incyte Corporation

Terminated

Phase 2 Study of Ruxolitinib Versus Anagrelide in Subjects With Essential Thrombocythemia Who Are Resistant to or Intolerant of Hydroxyurea (RESET-272)

MPN (Myeloproliferative Neoplasms)

United States
Incyte Corporation

Completed

A Safety and Tolerability Study of INCAGN02390 in Select Advanced Malignancies

Melanoma | Renal Cell Carcinoma | Cervical Cancer | Stomach Cancer | Small Cell Lung Cancer | Hepatocellular Carcinoma | Gastric Cancer | Esophageal Cancer | Ovarian Cancer | NSCLC | Mesothelioma | Squamous Cell Carcinoma of the Head and Neck | Non-small Cell Lung Cancer | Gastroesophageal Junction Cancer | Urothelial... and other conditions

United States
Amorepacific Corporation

Completed

Efficacy and Safety of AP Collagen Peptide on the Skin

Dry Skin

Korea, Republic of
Glaukos Corporation

Active, not recruiting

iStent Inject Trabecular Micro-Bypass System Continuation Post-Approval Study

Glaucoma, Open-Angle

United States
Masimo Corporation

Completed

Oxygen Reserve Index (ORi) Validation of INVSENSOR00029

Healthy

United States
Masimo Corporation

Completed

Rad-67 Repeatability and Reproducibility

Healthy

United States

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