Clinical Trials Sponsored by Goethe University

Total 222158 results

Goethe University

Recruiting

Volatiles in Critical Care After Free Flap Surgery

Sedation Set-up Time | Additional Time Required for Volatile Sedation

Germany
Goethe University

Completed

Blinatumomab in Adult Patients With Minimal Residual Disease (MRD) of B-precursor Acute Lymphoblastic Leukemia

ALL, Recurrent, Adult

Germany
Goethe University

Completed

German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (06/99)

Adult Acute Lymphocytic Leukemia

Germany
Goethe University

Completed

Treatment of Elderly Patients (>65 Years) With Acute Lymphoblastic Leukemia

Adult Acute Lymphocytic Leukemia

Germany
Goethe University

Completed

Study of Frontline Dasatinib Plus Chemotherapy in Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (PH+ALL)

Philadelphia Positive Acute Lymphoblastic Leukemia

Germany
Goethe University

Completed

Evaluation of Sedation in COVID-19 ARDS

Severe Acute Respiratory Syndrome Coronavirus 2 | Prone Position | Pulmonary Ventilation | Hypnotics and Sedatives

Germany
Goethe University

Completed

Assessment of Hemostatic Profile in Liver Cirrhosis

Coagulation Disorder

Germany
Goethe University

Unknown

High-intensity Functional Circuit Training and Cognitive Function

Exercise | Cognition
Goethe University

Completed

Implication of Stiffness of the Hamstrings, Achilles Tendon and Calf Muscles for Jumping Performance

Tissue Compliance

Germany
Goethe University

Unknown

Characteristics of Primary and Plasmatic Hemostasis in Preeclampsia

Platelet Function | Coagulation Disorder, Blood
Goethe University

Unknown

Point-of-Care Testing in Coagulopathic Patients Undergoing Cardiac Surgery - a Multicenter Study (MultiPOC)

Coagulopathy During Cardiac Surgery

Germany, Austria
Goethe University

Unknown

Diagnostic Algorithm for Appendizitis (DIALAPP) (DIALAPP)

Reduction of Negative Appendectomy Rate

Germany
Goethe University

Completed

Cytokines in Papillon-Lefèvre Syndrome

Papillon-Lefevre Disease

Germany
Goethe University

Completed

Comparative Study of Intraoperative MRI-guided vs. Conventional Glioma Surgery

Glioma

Germany
Goethe University

Recruiting

Evaluation of Peripartum Blood Loss and Postpartum Anaemia in Macrosomia & Gemini

Bloodloss in Pregnancy

Germany
Goethe University

Completed

Treatment of Older Patients With B-precursor ALL With Sequential Dose Reduced Chemotherapy and Blinatumomab (EWALL-BOLD)

B-Precursor ALL

Germany
Goethe University

Active, not recruiting

Optimization of Therapy in Adult Patients With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma by Individualised, Targeted and Intensified Treatment

Acute Lymphoblastic Leukemia | Lymphoblastic Lymphoma

Germany
Goethe University

Completed

Therapy and Outcome of Prolonged Veno-venous ECMO Therapy of Critically Ill ARDS Patients.

Outcome, Fatal | Extracorporeal Membrane Oxygenation Complication

Germany
Goethe University

Completed

Treatment of Hyperuricemia With Rasburicase in Patients With Acute Lymphoblastic Leukemia or High Grade Lymphoma

Adult Acute Lymphocytic Leukemia | High-grade Lymphoma

Germany
Goethe University

Completed

A Phase I, Dose-finding Study of BEZ235 in Adult Patients With Relapsed or Refractory Acute Leukemia

Acute Lymphoblastic Leukemia | Leukemia, Myelocytic, Acute | Chronic Myelogenous Leukemia With Crisis of Blast Cells

Germany
Goethe University

Completed

Treatment of Acute Lymphoblastic Leukemia or Aggressive Lymphoma With Relapse in Central Nervous System With Depocyt

Adult Acute Lymphocytic Leukemia

Germany
Goethe University

Completed

Prospective Electroencephalography Evaluation of Sedation in COVID-19

Pathologic Processes | Acute Respiratory Distress Syndrome | Corona Virus Infection | Electroencephalogram | Conscious Sedation

Germany
Goethe University

Enrolling by invitation

Long-term Results After Systematic Periodontal Therapy (SYSPERIO10)

Tooth Loss

Germany
Goethe University

Completed

Detecting Sepsis in Patients With Severe Subarachnoideal Hemorrhage

Sepsis | Subarachnoid Hemorrhage | Subarachnoid Hemorrhage, Aneurysmal | Sepsis Syndrome | Sepsis, Severe | Sepsis Bacterial

Germany
Goethe University

Completed

Study on the Psychotherapeutic Treatment of Chronic Nightmares

Nightmare Disorder

Germany
Goethe University

Completed

Gingival Bleeding and Von Willebrand Disease Typ 2 and 3

Von Willebrand Diseases | Gingival Bleeding

Germany
Goethe University

Unknown

Drug Monitoring in Critically Ill Patients During Extracorporeal Life Support

Drug Monitoring of Antiinfectives in Critically Ill Patients Receiving Extracorporeal Life Support

Germany
Goethe University

Unknown

Neurophysiologic Correlates of Movement Planning During Complex Jump Landing Tasks and the Role of Cognitive Function

Anterior Cruciate Ligament Reconstruction

Germany
Goethe University

Completed

Faster Back Home: Efficacy of a High-intensity Endurance Training (Fit15)

Healthy

Germany
Goethe University

Completed

Monitoring Platelet Function During Continuous Hemodialysis

Platelet Function

Germany
Goethe University

Completed

Cervical Kinematics' Reliability: Zero Positioning Using a 3-D-bulls Eye Spirit Level

Kinematics | Reliability | Cervical

Germany
Goethe University

Completed

Activated MMP-8 as Diagnostic Test for Periodontitis (MMP-8)

Generalized Chronic Periodontitis
Goethe University

Completed

IgM-enriched Immunoglobulin Attenuates Systemic Endotoxin Activity in Early Severe Sepsis

Sepsis

Germany
Goethe University

Completed

Feedback and Psychotherapeutic Competencies

Mental Disorders

Germany
Goethe University

Completed

Influence of Extracorporeal Circulation on Platelet Function of Patients Undergoing Cardiac Surgery

Acquired Platelet Function Disorder

Germany
Goethe University

Completed

Follow-up of Children With Gastrointestinal Malformations and Postnatal Surgery (FraMal)

Digestive System Abnormalities

Germany
Goethe University

Completed

Efficacy of Cognitive Restructuring and Imagery Modification to Reduce the Feeling of Being Contaminated After Childhood Sexual Abuse

Posttraumatic Stress Disorder | Sexual Abuse

Germany
Goethe University

Completed

Monitoring of the Cerebral Tissue Oxygenation and Perfusion in the Adapting Climber During Sleep in High Altitude (PerOxySleep)

Environmental Sleep Disorder | Cheyne-Stokes Respiration | Altitude Sickness

Germany
Goethe University

Completed

Modified Ultrafiltration in Cardiac Surgery

Blood Loss | Coagulopathy | Rethoracotomy | Transfusion Requirements

Germany
Goethe University

Recruiting

MAIN-IMAGE Registry (MAIN-IMAGE)

Coronary Artery Disease

Germany
Goethe University

Not yet recruiting

EPIDURAL- Evaluation of Preexisting Information Regarding Neuroaxial Procedures for Labour Analgesia (EPIDURAL)

Neuroaxial Analgesia Procedures

Germany
Goethe University

Recruiting

Prospective Evaluation of Jugular Vein Thrombi After CPB Cervical Cannulation

Post-interventional VJI Thrombi After CPB

Germany
Goethe University

Recruiting

Additional Chemotherapy for EGFRm Patients With the Continued Presence of Plasma ctDNA EGFRm at Week 3 After Start of Osimertinib 1st-line Treatment (PACE-LUNG)

NSCLC Stage IV | NSCLC Stage IIIB

Germany
Goethe University

Recruiting

Characterization of Metabolic Changes in the Glioma Tumor Tissue Induced by Transient Fasting (ERGO3) (ERGO3)

Glioma, Mixed

Germany
Goethe University

Recruiting

GMALL Registry and Collection of Biomaterial: Prospective Data Collection Regarding Diagnosis, Treatment and Outcome of Adult Acute Lymphoblastic Leukemia (ALL) Patients and Related Diseases Associated With a Prospective Collection of Biomaterial (GMALLregistry)

Leukemia | Non-Hodgkin's Lymphoma | Acute Lymphoblastic Leukemia

Germany
Goethe University

Active, not recruiting

Randomized Phase-II Study of Nivolumab Plus Ipilimumab vs. Standard of Care in Untreated and Advanced Non-clear Cell RCC

Metastatic Renal Cell Carcinoma

Spain, Netherlands, United Kingdom, France, Germany, Belgium, Czechia
Goethe University

Completed

Prospective Evaluation of Volatile Sedation After Heart Valve Surgery

Valve Heart Disease | Awakening Early

Germany
Goethe University

Active, not recruiting

Capecitabine-based Chemoradiotherapy in Combination With the IL-1 Receptor Antagonist Anakinra for Rectal Cancer Patients (ACO/ARO/AIO-21)

Rectal Cancer

Germany
Goethe University

Active, not recruiting

Radiochemotherapy +/- Durvalumab for Locally-advanced Anal Carcinoma. A Multicenter, Randomized, Phase II Trial of the German Anal Cancer Study Group (RADIANCE)

Anal Cancer | Anal Carcinoma | Anal Cancer Stage III | Anal Cancer Stage II

Germany, Switzerland, Austria
Goethe University

Completed

Mechanical Cardiopulmonary Resuscitation During Treatment of Acute Respiratory Failure Through Extracorporeal Membrane Oxygenation.

Cardiovascular Resuscitation | Venovenous Extracorporeal Membrane Oxygenation

Germany

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