Clinical Trials Sponsored by HLT Inc.

Total 35480 results

Cascadian Therapeutics Inc.

Completed

Phase I Trial of PX-478

Lymphoma | Advanced Solid Tumors

United States
Cascadian Therapeutics Inc.

Completed

A Trial of PX-12 in Patients With a Histologically or Cytologically Confirmed Diagnosis of Advanced or Metastatic Cancer

Metastatic Cancer | Advanced Cancer

United States
Cascadian Therapeutics Inc.

Completed

Phase 1 and 2 Study of PX-866 and Cetuximab

Incurable Metastatic Colorectal Carcinoma | Incurable Progressive, Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

United States, Canada
Cascadian Therapeutics Inc.

Terminated

Study of PX-866 and Vemurafenib in Patients With Advanced Melanoma

Advanced BRAF-mutant Cancers

United States
Ocular Therapeutix, Inc.
ORA, Inc.

Completed

OTX-14-007: A Phase 3 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Chronic Allergic Conjunctivitis

Chronic Allergic Conjunctivitis
Seagen Inc.
Millennium Pharmaceuticals, Inc.

Completed

A Pivotal Open-Label Trial of Brentuximab Vedotin for Hodgkin Lymphoma

Disease, Hodgkin

United States, France, Canada, Belgium, Italy
Eisai Korea Inc.

Completed

A Plan on Investigation and Collection of Aricept Safety Information With a Dose Increase on Alzheimer's Disease Patients (AID)

Alzheimer's Disease

Korea, Republic of
Seagen Inc.
Millennium Pharmaceuticals, Inc.

Completed

A Brentuximab Vedotin Trial for Patients Who Have Previously Participated in a Brentuximab Vedotin Study

Lymphoma, Non-Hodgkin | Lymphoma, Large-Cell, Anaplastic | Disease, Hodgkin

United States, France
Eisai Korea Inc.

Completed

Eribulin Mesylate Phase IV Clinical Trial in Korean Patients With Metastatic or Locally Advanced Breast Cancer (ESKIMO)

Breast Cancer | Breast Neoplasms

Korea, Republic of
KGK Science Inc.
Lonza Inc.

Completed

A Pilot Clinical Trial on the Efficacy of Two Carnitine-Based Products on Muscle Function in Healthy Older Adults (15CAHL)

Muscle Function

Canada
Astellas Pharma Inc
Agensys, Inc.

Completed

A Study of AGS-1C4D4 Given in Combination With Gemcitabine in Subjects With Metastatic Pancreatic Cancer

Pancreatic Cancer | Pancreatic Disease | Carcinoma, Pancreatic Ductal

Canada, United States, Spain, France, Russian Federation
Seagen Inc.
Millennium Pharmaceuticals, Inc.

Completed

A Phase 1 Study of Brentuximab Vedotin Combined With Multi-Agent Chemotherapy for Hodgkin Lymphoma

Disease, Hodgkin

United States, Canada
FORUM Pharmaceuticals Inc
Quintiles, Inc.

Completed

Phase 1 Study to Assess the Effects of EVP-6124 on the QT/QTc Interval in Healthy Subjects (TQT)

Healthy Subjects | Cardiac Repolarization
Neurovance, Inc.

Completed

A Study to Evaluate the Abuse Potential of EB-1020 Immediate-Release in Healthy Recreational Stimulant Users

Healthy Volunteers | Drug Users

United States
Astellas Pharma Inc
Agensys, Inc.

Completed

AGS-1C4D4 in Patients With Advanced Hormone Refractory Prostate Cancer

Prostate Cancer

United States
Neurovance, Inc.

Completed

A Study to Evaluate the Safety, Tolerance, and Pharmacokinetic and Pharmacodynamic Profile Of 1 SR Formulation of EB-1020

Normal, Healthy Volunteers

Australia
Savara Inc.
INC Research Limited

Completed

Inhaled Vancomycin Tolerability, Safety and Pharmacokinetics

Healthy | Cystic Fibrosis

Australia
Eisai Korea Inc.

Terminated

Correlation Between Regional Brain Volume and Response to Donepezil Treatment in AD Patients

Alzheimer's Disease

Korea, Republic of
Astellas Pharma Inc
Agensys, Inc.

Terminated

A Phase 1 Study of the Safety and Pharmacokinetics of AGS-16M18 in Subjects With Advanced Renal Cell Cancer

Kidney Neoplasms | Carcinoma, Renal Cell | Kidney Diseases

United States
Astellas Pharma Inc
Agensys, Inc.

Terminated

A Study of the Safety and Pharmacokinetics of AGS-8M4 Given in Combination With Chemotherapy in Women With Ovarian Cancer

Carcinoma | Ovarian Diseases | Ovarian Neoplasms | Ovarian Cancer

United States
Astellas Pharma Inc
Agensys, Inc.

Completed

A First in Man Study to Determine the Safety at Various Dose Levels of AGS-16M8F in Advanced Kidney Cancer

Renal Cell Carcinoma | Pharmacokinetics of AGS-16M8F

United States
Eisai Korea Inc.

Completed

Low and High Dose Zonisamide in Children as Monotherapy

Epilepsy

Korea, Republic of
Labopharm Inc.
Algorithme Pharma Inc

Completed

Comparative Bioavailability Study of Extended-release and Immediate-release Trazodone in Healthy Adult Volunteers

Healthy

Canada
Eisai China Inc.

Completed

Efficacy and Safety of Cinitapride Tablets in the Treatment of Mild to Moderate Functional Dyspepsia

Dyspepsia

China
Hygieia, Inc
TKL Research, Inc.

Completed

Efficacy and Safety of Frequently Modified Intensive Insulin

Diabetes

United States
Ocuphire Pharma, Inc.
Viatris Inc.

Recruiting

Safety and Efficacy of 0.75% Phentolamine Ophthalmic Solution in Subjects With Post-refractive Surgery Visual Disturbances (LYNX-2)

Mesopic Vision | Night Vision Loss

United States
GB002, Inc.

Not yet recruiting

Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT)

Pulmonary Arterial Hypertension

United States
Eisai Korea Inc.

Recruiting

A Study of Jyseleca Tablet (Filgotinib Maleate) in Korean Participants

Arthritis, Rheumatoid | Colitis, Ulcerative

Korea, Republic of
ORA, Inc.
Stuart Therapeutics, Inc.

Recruiting

Safety and Efficacy of ST-100 (Vezocolmitide) Ophthalmic Solution 60 μg/ml Ophthalmic Solution in Subjects Diagnosed With Dry Eye Disease (DED)

Dry Eye Disease

United States
Lucid Diagnostics, Inc.

Recruiting

CLUE: CLinical Utility Study of EsoGuard (PR-0410)

Barrett Esophagus | Barretts Esophagus With Dysplasia | Esophagus Adenocarcinoma

United States
Neuracle Genetics, Inc
ORA, Inc.

Recruiting

NG101 AAV Gene Therapy in Subjects With Wet Age-Related Macular Degeneration

Age-Related Macular Degeneration

Canada
Ceragem Clinical Inc.

Not yet recruiting

CETIC-I (CEra Traction Improves Cervical Kyphosis -I)

Kyphosis | Cervical Kyphosis | Cervical Lordosis
Eisai Korea Inc.

Recruiting

A Post Marketing Surveillance Study of Equfina Tablet 50 Milligram (mg)

Parkinson Disease

Korea, Republic of
HBI Solutions Inc.
mProbe Inc.

Not yet recruiting

Cohort Study to Evaluate the Relapse Risk Test in Colorectal Cancer

Colorectal Cancer
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Levothyroxine Sodium Tablets 200 mg to Synthroid Tablets 200 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Food Study of Cetirizine HCl Tablets 10 mg and Zyrtec® 10 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Alprazolam Extended-Release Tablets 1 mg to Xanax XR Tablets 1 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Paroxetine Hydrochloride Controlled-Release Tablets 25 mg to Paxil CR™ Tablets 25 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fed Study of Anagrelide Hydrochloride Capsules 1 mg to Agrylin® Capsules 1 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fed Study of Amlodipine and Benazepril HCl Capsules 10 mg/20 mg to Lotrel® Capsules 10 mg/20 mg

Healhty

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Lamotrigine Tablets 25 mg to Lamictal® Tablets 25 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fed Study of Balsalazide Disodium Capsules 750 mg and Colazal® Capsules 750 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Olanzapine Tablets 5 mg and Zyprexa® Tablets 5 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Steady-State Study of Extended Phenytoin Sodium Capsules 100 mg and Dilantin® Kapseals® 100 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Midodrine HCl Tablets 5 mg and ProAmatine® Tablets 5 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Food Study Metformin Hydrochloride ER Tablets 500 mg and Glucophage® XR 500 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Oxybutynin Chloride ER Tablets 10 mg and Ditropan XL® Tablets 10 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Levothyroxine Sodium Tablets 300 μg to Synthroid® Tablets 300 μg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Metolazone Tablets 10 mg and Zaroloxyn® Tablets 10 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Food Study of Propranolol Hydrochloride Extended-Release Capsules 160 mg and Inderal® LA Capsules 160 mg

Healthy

United States

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