Clinical Trials Sponsored by Health ResearchTx, LLC (HRTX)

Total 142 results

Boehringer Ingelheim
Health ResearchTx, LLC (HRTX); inVentiv Health Clinical (iVH); United States...

Completed

The Comparative Safety and Effectiveness of Dabigatran, Versus Rivaroxaban, and Apixaban Utilized in the Department of Defense Non-Valvular Atrial Fibrillation Patient Population: A Retrospective Database Analysis

Atrial Fibrillation

United States
Bayer
Janssen Research & Development, LLC; Population Health Research Institute

Terminated

Rivaroxaban Versus Aspirin in Secondary Prevention of Stroke and Prevention of Systemic Embolism in Patients With Recent Embolic Stroke of Undetermined Source (ESUS) (NAVIGATE ESUS)

Stroke

Denmark, France, Spain, China, United States, Switzerland, Germany, Greece, Korea, Republic of, Portugal, Japan, Israel, Canada, Australia, Turkey, Russian Federation, Sweden, Austria, Czechia, Poland, United Kingdom, Belgium, Brazil, Hungar... and more
Bayer
Janssen Research & Development, LLC; Population Health Research Institute

Completed

Rivaroxaban for the Prevention of Major Cardiovascular Events in Coronary or Peripheral Artery Disease (COMPASS)

Prevention & Control

Belgium, Finland, France, China, United States, Colombia, Ireland, Philippines, Japan, Hungary, Canada, Germany, Australia, Chile, Czechia, Korea, Republic of, Malaysia, Brazil, Denmark, Israel, Russian Federation, South Africa, Ecu... and more
Bayer
Janssen Research & Development, LLC; RTI Health Solutions

Completed

Patient and Physician Knowledge of Key Safety Messages

Anticoagulation

Germany, United Kingdom, France, Spain
Population Health Research Institute
Merck Sharp & Dohme LLC

Completed

Remission Evaluation of a Metabolic Intervention in Type 2 Diabetes With Sitagliptin (REMIT-Sita)

Type 2 Diabetes Mellitus

Canada
Medstar Health Research Institute
Merck Sharp & Dohme LLC

Completed

Does the HPV Vaccine Cause the Same Response in Adolescent Kidney and Liver Transplant Patients as in Healthy Controls?

Cervical Cancer | Warts | Hpv

United States
Rajavithi Hospital
Health Systems Research Institute; Google LLC.

Recruiting

Implementation of an Integrated System of Artificial Intelligence and Referral Tracking for Real-time Diabetic Retinopathy Screening

Diabetic Retinopathy | Artificial Intelligence | Screening

Thailand
Tian Medical Inc.
TAMM Net, Inc.; Clinvest Research, LLC; Ki Health Partners. LLC

Completed

Efficacy and Safety of Tx360® Transnasal Sphenopalatine Ganglion Block in the Treatment of Chronic Migraine

Headache, Migraine

United States
MultiCare Health System Research Institute
Merck Sharp & Dohme LLC

Active, not recruiting

Group Intervention on Vaccine Confidence

Vaccination Refusal

United States
Wake Forest University Health Sciences
Janssen Research & Development, LLC

Withdrawn

Phase II Study of Daratumumab Pre-Mobilization and Post-ASCT in Multiple Myeloma

Multiple Myeloma

United States
PETHEMA Foundation
Merck Sharp & Dohme LLC; Adknoma Health Research

Completed

Pembrolizumab (MK-3475) in MM Patients With Residual Disease

Multiple Myeloma

Spain
Heart Center Research, LLC
Boston Scientific Corporation

Recruiting

Diuretics vs. Afterload Reduction for Treatment of HeartLogic Alerts (DART-HA)

Heart Failure, Congestive

United States
Sydney Centre for Reproductive Health Research
Merck Sharp & Dohme LLC

Unknown

A New Treatment Option for Heavy Menstrual Bleeding

Menorrhagia

Australia
Public Health Vaccines LLC
Biomedical Advanced Research and Development Authority

Recruiting

Study to Evaluate the Recombinant Vesicular Stomatitis Virus (rVSV)-Marburg Virus Vaccine Candidate (PHV01) in Healthy Adult Subjects (PHV01)

Marburg Virus Disease

United States
McMaster University
Canadian Institutes of Health Research (CIHR); Bioventus LLC

Terminated

Randomized Trial in knEe Osteoarthritis Using Low Intensity Ultrasound - Evaluating Feasibility (RELIEF) (RELIEF)

Knee Osteoarthritis

Canada
Heart Rhythm Clinical and Research Solutions, LLC
Abbott

Terminated

Real-World Evidence Registry to Assess Outcomes of Catheter Ablation for Atrial Fibrillation (DYNAMIC AF Registry)

Atrial Fibrillation

United States
Guardant Health, Inc.
Premier Research Group plc

Active, not recruiting

Evaluation of the ctDNA LUNAR Test in an Average Patient Screening Episode (ECLIPSE)

Colorectal Cancer

United States
University Health Network, Toronto
Patient-Centered Outcomes Research Institute; M.D. Anderson Cancer Center; Applied... and other collaborators

Active, not recruiting

PRO-ACTIVE: Prophylactic Swallow Intervention for Patients Receiving Radiotherapy for Head and Neck Cancer (PRO-ACTIVE)

Dysphagia

United States, Canada
Sunnybrook Health Sciences Centre
Merck Sharp & Dohme LLC; Ozmosis Research Inc.

Completed

A Proof of Principle Study of Pembrolizumab With SBRT in TKI mRCC Patients (OZM-065)

Stage IV Renal Cell Cancer AJCC V7

Canada
Janssen Research & Development, LLC
The George Institute for Global Health, Australia

Completed

Evaluation of the Effects of Canagliflozin on Renal and Cardiovascular Outcomes in Participants With Diabetic Nephropathy (CREDENCE)

Diabetes Mellitus, Type 2 | Diabetic Nephropathy

United States, Canada, France, Germany, Poland, Ukraine, United Kingdom, China, Taiwan, Spain, Argentina, Colombia, Mexico, Bulgaria, India, Malaysia, Romania, Serbia, South Africa, Japan, Australia, Korea, Republic of, Chile, New Zealand and more
Center for Epidemiology and Health Research, Germany
Merck Sharp & Dohme LLC

Completed

Nexplanon Observational Risk Assessment Study (NORA) (NORA)

Contraception

Germany
Janssen Research & Development, LLC
The George Institute for Global Health, Australia

Completed

CANVAS - CANagliflozin cardioVascular Assessment Study (CANVAS)

Cardiovascular Diseases | Diabetes Mellitus, Type 2 | Risk Factors

United States, Australia, Poland, Ukraine, United Kingdom, Belgium, Germany, France, Spain, Argentina, Colombia, Israel, Mexico, India, Canada, Netherlands, Sweden, Malaysia, New Zealand, Estonia, Russian Federation, Hungary, Norway, ... and more
Janssen Research & Development, LLC
The George Institute for Global Health, Australia

Completed

A Study of the Effects of Canagliflozin (JNJ-28431754) on Renal Endpoints in Adult Participants With Type 2 Diabetes Mellitus (CANVAS-R)

Diabetes Mellitus, Type 2 | Albuminuria

Australia, France, Italy, Poland, Ukraine, United Kingdom, United States, China, Belgium, Germany, Taiwan, Spain, Argentina, Mexico, Malaysia, Canada, Netherlands, Korea, Republic of, New Zealand, Brazil, Russian Federation, Puerto... and more
Heart Rhythm Clinical and Research Solutions, LLC
Attune Medical

Not yet recruiting

REView of ProcEdural FactoRs and Outcomes After Atrial Fibrillation Ablation With Active Esophageal COOLing: A Sub-Study of the REAL AF Registry (EVERCOOL AF)

Atrial Fibrillation
Volta Medical
Heart Rhythm Clinical and Research Solutions, LLC

Recruiting

Clinical and Healthcare Outcomes From Real-World Use in the United States of a Companion AI During AF Ablation (COMPANION AI)

Atrial Fibrillation

United States
Northwell Health
Merck Sharp & Dohme LLC; Thrasher Research Fund; New York State Department of...

Completed

The Effect of Montelukast on Asthma Control in Overweight/Obese Atopic Asthmatics

Inflammation | Obesity | Asthma

United States
Center for Epidemiology and Health Research, Germany
Merck Sharp & Dohme LLC; Theramex

Completed

Prospective Controlled Cohort Study on the Safety of a Monophasic Oral Contraceptive Containing Nomegestrol Acetate (2.5mg) and 17ß-estradiol (1.5mg) (PRO-E2)

Contraception

Germany
Merck Sharp & Dohme LLC
McGill University Health Centre/Research Institute of the McGill University...

Completed

Assessment of the Fungal Infection Incidence Across Canada for High Risk Participants With Hematological Disease (P07501) (TRAFIC)

Leukemia | Mycoses
Heart Rhythm Clinical and Research Solutions, LLC
Biosense Webster, Inc.

Recruiting

The Long-term Safety and Effectiveness Evaluation of the QDOT MICRO System Use in Conjunction With VISITAG SURPOINT Module for the Treatment of Symptomatic Drug Refractory Paroxysmal Atrial Fibrillation. (QDOT PAS)

Paroxysmal Atrial Fibrillation

United States
Heart Rhythm Clinical and Research Solutions, LLC
Boston Scientific Corporation

Not yet recruiting

A Registry Based Collaborative to Measure Efficiency, Effectiveness, and Safety of Farapulse PFA Technology for AF (DISRUPT-AF)

Atrial Fibrillation

United States
McGill University Health Centre/Research Institute...
Merck Sharp & Dohme LLC

Completed

Raltegravir-based Antiretroviral Versus Maintaining Any Other Antiretroviral Therapy in HIV Mono-infected Patients

Fatty Liver | HIV | Nonalcoholic Steatohepatitis

Canada
McGill University Health Centre/Research Institute...
Merck Sharp & Dohme LLC

Completed

Perceptual-Cognitive Training After a Mild Traumatic Brain Injury: Towards a Sensitive Marker for Recovery

Brain Concussion | Concussion | Post-Concussion Symptoms

Canada
McGill University Health Centre/Research Institute...
Merck Sharp & Dohme LLC

Completed

Protease Inhibitor vs. Raltegravir-based ART and Inflammation in HIV Infection

HIV

Canada
McGill University Health Centre/Research Institute...
Merck Sharp & Dohme LLC

Withdrawn

Immune Responses in Patients Treated With Raltegravir (RAG-1/2)

HIV Infections

Canada
Heart Rhythm Clinical and Research Solutions, LLC
Boston Scientific Corporation

Recruiting

Safety and Efficacy of Workflows of High Volume Single Operators in a LAAO Device Implant Procedural Day

Atrial Fibrillation

United States
Heart Rhythm Clinical and Research Solutions, LLC
Biosense Webster, Inc.

Recruiting

Real-world Experience of Catheter Ablation for the Treatment of Paroxysmal and Persistent Atrial Fibrillation (REAL-AF)

Paroxysmal Atrial Fibrillation | Persistent Atrial Fibrillation

United States
Jaeb Center for Health Research
Juvenile Diabetes Research Foundation; National Eye Institute (NEI); National... and other collaborators

Completed

A Pilot Study Evaluating Photobiomodulation Therapy for Diabetic Macular Edema (AE)

Diabetic Macular Edema

United States
National Opinion Research Center
Merck Sharp & Dohme LLC; Emory University; Grady Health System

Terminated

Registry-based HCV Care Cascade Navigation at Atlanta's Grady Memorial Hospital (EZ-C)

Hepatitis C

United States
University of Calgary
Merck Sharp & Dohme LLC; Canadian Institutes of Health Research (CIHR)

Completed

Paroxysmal Atrial Fibrillation: Role of Inflammation, Oxidative Stress Injury and Effect of Statins (PAFRIOSIES)

Atrial Fibrillation

Canada
Integrated Medical Research LLC
New York State Department of Health; Alere San Diego

Completed

Improving the Management of Acute Coronary Syndromes in the Emergency Department (RACE)

Acute Coronary Syndrome

United States
University of California, Davis
Thrasher Research Fund; California Department of Health Services; University...

Completed

Feasibility and Pilot Efficacy of Flash-heated Breast Milk to Reduce Maternal-to-Child-Transmission of HIV in Tanzania (Flash-heat)

HIV Infections

United States
Providence Health & Services
MedImmune LLC; Providence Cancer Center, Earle A. Chiles Research Institute

Active, not recruiting

Study of MEDI0562 Prior to Surgical Resection in Head and Neck Squamous Cell Carcinoma (HNSCC) or Melanoma

Melanoma | Head and Neck Cancer | Carcinoma, Squamous Cell | Head and Neck Squamous Cell Carcinoma | Cell Cancer, Squamous

United States
Axio Research. LLC
National Heart, Lung, and Blood Institute (NHLBI); Abbott

Terminated

Niacin Plus Statin to Prevent Vascular Events

Myocardial Infarction | Heart Diseases | Cardiovascular Diseases | Coronary Disease | Atherosclerosis | Cerebrovascular Accident

United States, Canada
Center for Epidemiology and Health Research, Germany
Gedeon Richter Plc.

Terminated

European Active Surveillance Study Comparing Regimens of Administration in Combined Hormonal Contraception (EURAS-CORA)

Contraception

Germany
West Penn Allegheny Health System
Merck Sharp & Dohme LLC; Allegheny Singer Research Institute (also known as...

Completed

The Natural History of Viral Upper Respiratory Infections in Children Aged 6 to Less Than 14 Years

Common Cold | Upper Respiratory Infection

United States
Allegheny Singer Research Institute (also known...
Connective Tissue Matrix Biomedical, LLC

Recruiting

Connective Tissue Matrix for Rotator Cuff Tendinopathy (CTM RCT)

Tendinopathy | Shoulder Pain | Rotator Cuff Tendinitis | Rotator Cuff Tendinosis

United States
ReAlta Life Sciences, Inc.
Premier Research Group plc

Recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of RLS-0071 in Newborns With Moderate or Severe Hypoxic-Ischemic Encephalopathy Undergoing Therapeutic Hypothermia (STAR)

Hypoxic-Ischemic Encephalopathy

United States
Thomas Schricker
Merck Sharp & Dohme LLC

Terminated

Surgical Conditions During Vocal Cord Surgery Requiring Jet Ventilation With Moderate vs. Deep Neuromuscular Block

High-Frequency Jet Ventilation | Vocal Cord Resection

Canada
University of Oxford
National Health and Medical Research Council, Australia; Merck Sharp & Dohme... and other collaborators

Completed

Study of Heart and Renal Protection (SHARP)

Kidney Disease, Chronic

United Kingdom
Providence Health & Services
Merck Sharp & Dohme LLC; Providence Cancer Center, Earle A. Chiles Research...

Active, not recruiting

MK-3475 and Gemcitabine in Non-Small Cell Lung Cancer (NSCLC)

Carcinoma, Non-Small-Cell Lung

United States

Clinical Trials Sponsored by Health ResearchTx, LLC (HRTX)

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