Clinical Trials Sponsored by IRCCS Ospedale San Raffaele

Total 615 results

IRCCS San Raffaele
High Research

Recruiting

Sacituzumab Govitecan, Preceding Radical Cystectomy, in Treating Patients With Muscle-invasive Bladder Cancer

Urothelial Carcinoma

Italy
Paolo Ghia

Recruiting

Venetoclax, Rituximab and Ibrutinib in TN Patients With CLL Undetectable Minimal Residual Disease (uMRD) in Treatment-naïve Patients With Chronic Lymphocytic Leukemia (CLL) (VALUABLE)

Chronic Lymphocytic Leukemia (CLL)

Italy
Germano Melissano

Suspended

Cryoablation of Intercostal Nerves for Better Control of Postoperative Pain After Thoracic and Thoracoabdominal Open Surgery

Aneurysm

Netherlands, Germany, Italy, United Kingdom, Austria, France, Portugal, Switzerland
Ciceri Fabio

Completed

Phase II Trial in Elderly Patients With AML or MDS in Complete Remission Not Eligible for Allogenic Transplant (FLAT-Auto)

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Transplant-Related Hematologic Malignancy

Italy
Ciceri Fabio

Completed

Peripheral Blood Stem Cell Transplantation From Family Haploidentical Donors in Patients With Myelodysplastic Syndrome and Acute Leukemia Under Primary Prophylaxis With Posaconazole (SIR-POSA)

Myelodysplastic Syndromes | Fungal Infection | Graft Vs Host Disease | Leukemia, Acute | Transplant-Related Hematologic Malignancy

Italy
Genenta Science
IRCCS San Raffaele

Terminated

A Phase I/II Study Evaluating Temferon in Multiple Myeloma Patients With Early Relapse After Front Line Therapy (TEM-MM)

Multiple Myeloma

Italy
Antonio Secchi

Completed

SARS-CoV2 (COVID-19) Seroepidemiological Transplanted Subjects (Kidney, Kidney-pancreas, Pancreas, Langerhans Islets)

Kidney Transplant | Pancreatic Transplat | Pancreatic Islets Langerhans

Italy
Michele Reni

Unknown

Analysis Of The Anxiety-Depressive Pattern, Quality Of Life And Assessment Of Personality in Patients With Pancreatic Ductal Adenocarcinoma (PACT24)

Pancreas Adenocarcinoma

Italy
Michele De Bonis

Completed

Mitral Regurgitation in Hypertrophic Obstructive Cardiomyopathy: Fix it in a Simple, Effective and Durable Way!

Mitral Regurgitation | Hypertrophic Obstructive Cardiomyopathy

Italy
Michele De Bonis

Completed

Long-term Results of Bilateral Thoracoscopic Ablation for Stand-alone Atrial Fibrillation

Atrial Fibrillation

Italy
Michele De Bonis

Completed

LOng-Term Fate of Moderate Aortic Regurgitation Left Untreated at the Time of Mitral Valve Surgery

Mitral Regurgitation | Aortic Regurgitation

Italy
Michele De Bonis

Completed

Fate of Moderate Secondary Mitral Regurgitation in Patients Undergoing Aortic Valve Surgery for Severe Aortic Regurgitation

Aortic Regurgitation | Functional Mitral Regurgitation

Italy
Michele De Bonis

Completed

Edge-To-Edge Technique Used as a Bailout in Case of Sub-Optimal Mitral Repair: Very Long-Term Results

Mitral Regurgitation

Italy
Michele De Bonis

Completed

Aortic Cross-clamp and Opening After Transcatheter Aortic Valve Implantation: a Real Issue?

Aortic Stenosis

Denmark, Hungary, Italy
Ospedale San Raffaele
Dompé Farmaceutici S.p.A

Completed

Nerve Growth Factor Eye Drops Treatment in Patients With Retinitis Pigmentosa and Cystoid Macular Edema (NEMO)

Retinitis Pigmentosa | Cystoid Macular Edema

Italy
Paolone Gaetano

Not yet recruiting

Study on the Chromatic Perception of Digital Systems in Aesthetic Field

Color Detection of Upper Central Incisors

Italy
Giulio Frontino

Not yet recruiting

Achieving Rapid, Safe and Sustained Glucose Control in Adolescents With Suboptimally Controlled Type 1 Diabetes Using Advanced Hybrid Closed Loop Systems

Diabetes Mellitus, Type 1
Massimo Falconi

Active, not recruiting

A New Scoring System for Perineural and Vascular Invasion in Pancreatic Cancer (VANISSh)

Pancreas Cancer

Italy
IRCCS San Raffaele
Gilead Sciences

Terminated

Switch From Dual Regimens Based on Dolutegravir Plus a Reverse Transcriptase Inhibitor to E/C/F/TAF in Virologically Suppressed, HIV-1 Infected Patients (Be-OnE) (Be-OnE)

HIV-1-infection

Italy
Enrico Tomasi

Completed

A Study on Behavior of Healthcare Professionals Who Handle Oral Solid Drug

Behavior

Italy
IRCCS San Raffaele
Fondazione Telethon

Active, not recruiting

Gene Therapy With Modified Autologous Hematopoietic Stem Cells for the Treatment of Patients With Mucopolysaccharidosis Type I, Hurler Variant (TigetT10_MPSIH)

Mucopolysaccharidosis IH

Italy
Emanuele Bosi

Terminated

Clinical Study for the Treatment With Interferon-ß-1a (IFNß-1a) of COVID-19 Patients (INTERCOP)

COVID-19 Virus Infection

Italy
IRCCS San Raffaele
Fondazione Telethon

Completed

Gene Therapy for ADA-SCID

Severe Combined Immunodeficiency Syndrome
Ospedale San Raffaele
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico; Ministry of Health...

Recruiting

Improving Health Care in Major Depressive Disorder (DepType)

Major Depressive Disorder

Italy
Ospedale San Raffaele
Juvenile Diabetes Research Foundation

Completed

Calcineurin Inhibitor (CNI)-Free Immunosuppressive Regimen in T1D Patients Receiving Islet Transplantation (ECIT-1)

Type 1 Diabetes

Italy, Switzerland
Prof. Massimo Filippi

Recruiting

Virtual-reality for Upper Limb Rehabilitation in People With Parkinson's Disease

Parkinson Disease

Italy
Francesco De Cobelli

Recruiting

Microwave Ablation for Treatment of Small Renal Tumors and Primary and Secondary Liver Neoplasms

Kidney Cancer | Renal Cell Carcinoma | Liver Cancer | Liver Metastasis Colon Cancer

Italy
Paolo Della Bella

Unknown

"Ventricular Tachycardia Ablation Registry".

Ventricular Tachycardia

Italy
Francesco De Cobelli

Completed

CT Radiomic Features of Pancreatic Neuroendocrine Neoplasms

Pancreatic Neuroendocrine Tumor

Italy
Francesco De Cobelli

Completed

Role of Post Surgery CT Following Laparoscopic Vertical Sleeve Gastrectomy (LSG-CT)

Obesity

Italy
Davide Di Santo

Unknown

Multiparametric Magnetic Resonance Imaging Versus Fine Needle Aspiration Cytology for Parotid Gland Neoplasms

Parotid Neoplasm | Parotid Cancer

Italy
Ospedale San Raffaele
Ministry of Health, Italy

Completed

Bone Marrow vs Liver as Site for Islet Transplantation (IsletBOM2)

Type 1 Diabetes

Italy
London Health Sciences Centre
Ospedale San Raffaele

Completed

Impact of Left Atrial Appendage Exclusion on Short-Term Clinical Outcomes and Long-Term Stroke Incidence

Atrial Fibrillation | Thromboembolism | Cerebrovascular Accident

Italy
IRCCS San Raffaele
Istituto Giannina Gaslini

Recruiting

Neuron-specific Humoral and Cellular Immune Correlates of Structural and Functional Brain Connectomics in Neuropsychiatric Lupus (INLES)

Systemic Lupus Erythematosus

Italy
Scarlata, Simone, M.D.
IRCCS San Raffaele

Recruiting

Flow Cytometry Analysis of Eosinophils in Severe Asthma Patients.

Severe Asthma

Italy
IRCCS San Raffaele
Bristol-Myers Squibb

Completed

Efficacy of Atazanavir/Ritonavir Monotherapy as Maintenance in Patients With Viral Suppression

HIV-1 Infection

Italy
IRCCS San Raffaele
Politecnico di Milano

Unknown

Monitoring Response to NAC and Prediction of pCR in Breast Cancer Patients Using Optical Imaging

Chemotherapy Effect | Breast Cancer Female

Italy
IRCCS San Raffaele
Bristol-Myers Squibb

Recruiting

An Open Label, Single-arm, Phase 2 Study of Neoadjuvant Nivolumab and Nab-paclitaxel Before Radical Cystectomy for Patients With Muscle-invasive Bladder Cancer (NURE-Combo) (NURE-Combo)

Muscle-Invasive Bladder Carcinoma

Italy
IRCCS San Raffaele Roma
SynAgile Corporation

Completed

Intermittent Oral Administration vs. Semi-continuous Intra-oral Administration of Levodopa/Carbidopa in Fluctuating Parkinsonian Patients (LDCD-001)

Parkinson Disease

Italy
Istituto Clinico Humanitas
IRCCS San Raffaele

Completed

The Embryologist's Impact on Blastocyst Vitrification and Thawing

Female Infertility

Italy
Francesco De Cobelli

Completed

Imaging Feature of SARS-CoV2 Infection (COVID19IF)

COVID | Viral Pneumonia

Italy
Istituto Clinico Humanitas
IRCCS San Raffaele

Unknown

Detection of High Expression Levels of EMT-Transcription Factor mRNAs in Patients With Pancreatic Cancer and Their Diagnostic Potential

Pancreatic Cancer

Italy
New Penta SRL
IRCCS San Raffaele

Unknown

Th Effect of Ketogenic Metabolic Nutritional Pattern on High-frequency Episodic Migraine (EMIKETO) (EMIKETO)

Brain Diseases | Overweight | Migraine | Weight Loss | Ketogenic Dieting

Italy
Azienda Socio Sanitaria Territoriale degli Spedali...
Ospedale San Raffaele

Unknown

Impact of Adjuvant Treatment With Aromatase Inhibitor on Sleep Disturbances in Postmenopausal Women With Endocrine Responsive Early Breast Cancer

Endocrine Responsive Early Breast Cancer

Italy
IRCCS Fondazione Stella Maris
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta; IRCCS Ospedale San... and other collaborators

Recruiting

The Fingerprinting of Inherited Leukoencephalopathies: A New Brain Imaging, Genetic and Clinical Assessment (FIABA)

Leukoencephalopathies

Italy
Università Vita-Salute San Raffaele
IRCCS San Raffaele; Merck Sharp & Dohme LLC

Unknown

GePheRal: Clinical Validation of the Genotypic Diagnosis of Hiv-1 Resistance to Raltegravir by Parallel Analysis of the Genotype and Phenotype Profiles of Resistance

HIV-1 Infected Patients | Fold-change Resistance | Resistance Mutations

Italy
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...
IRCCS San Raffaele; Istituto Clinico Humanitas; Istituti Clinici Zucchi

Completed

Clomifene Citrate as First Line Treatment in in Vitro Fertilization Cycles for Patients With Lower Ovarian Reserve (clomid)

Infertility

Italy
Centro Cardiologico Monzino
Humanitas Hospital, Italy; Treviso Regional Hospital; IRCCS Ospedale San Raffaele

Recruiting

Multiparametric SCores for Prediction of Myocardial fIbrosis in Patients With MITral vAlve pRolapse (SCIMITAR)

Mitral Valve Prolapse

Italy
Piemonti Lorenzo
Italian Diabetes Foundation

Completed

Monotherapy With Rapamycin in Long-standing Type 1 Diabetes (MONORAPA)

Diabetes Mellitus, Type 1

Italy
Fondazione Policlinico Universitario Agostino Gemelli...
IRCCS San Raffaele

Enrolling by invitation

EXploring novEl Molecular Determinants of DRAvet Syndrome Phenotype Heterogeneity (EXEDRA)

Dravet Syndrome

Italy

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