Clinical Trials Sponsored by Immunex/Berlex

Total 3501 results

St. Jude Children's Research Hospital
National Institutes of Health (NIH); Immunex/Berlex

Completed

Osteosarcoma1999-A Study Of Intensive Chemotherapy for Osteosarcoma

Osteosarcoma

United States, Chile
Amgen
Immunex Corporation

Terminated

Safety and Efficacy Study of Etanercept (Enbrel®) In Children With Systemic Onset Juvenile Rheumatoid Arthritis

Juvenile Rheumatoid Arthritis
Amgen
Immunex Corporation

Completed

Open-Label Extension Treatment With Etanercept (TNFR:Fc) for Participating Patients in Etanercept (TNFR:Fc) Clinical Trials

Rheumatoid Arthritis
Amgen
Immunex Corporation

Completed

Registry of Etanercept (Enbrel®) In Children With Juvenile Rheumatoid Arthritis

Juvenile Rheumatoid Arthritis
Amgen
Immunex Corporation

Completed

Study of Enbrel in Rheumatoid Arthritis (RA) Subjects With Comorbid Disorders

Rheumatoid Arthritis
Amgen
Immunex Corporation

Completed

Double-blind, Randomized, Placebo-controlled Phase 3 Study of Etanercept in the Treatment of Psoriatic Arthritis and Psoriasis

Psoriasis | Psoriatic Arthritis
Amgen
Immunex Corporation

Completed

Open-Label Extension Treatment With Etanercept (TNFR:Fc) for Participating Patients in Etanercept (TNFR:Fc) Clinical Trial 016.0012

Rheumatoid Arthritis
Amgen
Immunex Corporation

Completed

Enbrel Liquid Immunogenicity Protocol

Rheumatoid Arthritis
Abgenix
Immunex Corporation

Completed

ABX-EGF (a Monoclonal Antibody) Given to Patients With Prostate Cancer With or Without Tumor in Other Parts of the Body

Prostate Cancer

United States
Amgen
Immunex Corporation

Completed

An Open-Label Study to Assess the Rate of Failure of an Enbrel® (Etanercept) SureClick™ Auto-injector in Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis
Amgen
Immunex Corporation

Completed

The Efficacy and Safety of Adding Methotrexate to Etanercept in Psoriasis

Psoriasis
Amgen
Immunex Corporation

Completed

16.0040 Ankylosing Spondylitis Study

Ankylosing Spondylitis
Immune Design

Terminated

Phase 1b Safety Study of CMB305 in Patients With Locally Advanced, Relapsed, or Metastatic Cancer Expressing NY-ESO-1

Melanoma | Sarcoma | Ovarian Cancer | Non-small Cell Lung Cancer

United States
Immune Pharmaceuticals

Unknown

Evaluation of Safety, Efficacy, Pharmacokinetic and Pharmacodynamic of Bertilimumab in Patients With Active Moderate to Severe Ulcerative Colitis

Ulcerative Colitis, Active Severe | Ulcerative Colitis, Active Moderate

Israel
Immune Control

Unknown

Study of Fluphenazine in Relapsed or Relapsed-and-Refractory Multiple Myeloma

Multiple Myeloma

United States
Immune Design

Terminated

A Phase 3, Randomized, Double-blind, Placebo-controlled Study For Subjects With Locally-advanced Unresectable or Metastatic Synovial Sarcoma (V943-003, IMDZ-04-1702)

Sarcoma | Soft Tissue Sarcoma | Cancer | Synovial Sarcoma | Metastatic Sarcoma

United States, Canada
Immune Design

Completed

A Proof-of-Concept Trial of GLA-SE in Patients With Merkel Cell Carcinoma

Merkel Cell Carcinoma

United States
Immune Pharmaceuticals

Completed

Evaluation of Safety, Efficacy and Pharmacodynamic Effect of Bertilimumab in Patients With Bullous Pemphigoid

Pemphigoid, Bullous

United States, Israel
Immune Design

Completed

A Phase 1 Trial of NY-ESO-1 With GLA-SE in Patients With Unresectable or Metastatic Cancer

Melanoma | Sarcoma | Breast Cancer | Ovarian Cancer | Non-small Cell Lung Cancer

United States
Massachusetts General Hospital
Immunex Corporation

Terminated

Monitoring and Modifying Atherosclerosis in Psoriasis Patients Study (MMAPPS)

Psoriasis

United States
Smart Immune SAS

Recruiting

Development of a Cell Culture Process for the Production of Human T-lymphocyte Precursors (SMART101-HV1)

Healthy Volunteers

France
Immune Biosolutions Inc

Completed

Study in Adults to Assess the Safety and Efficacy of Inhaled IBIO123, for Post-exposure Prophylaxis of COVID-19

COVID-19

South Africa, Ukraine
Repertoire Immune Medicines

Terminated

RPTR-168 in Patients With Human Papillomavirus Strain 16 (HPV-16) E6/E7 Positive Tumors and Melanoma

Melanoma | Cervical Cancer | Head and Neck Squamous Cell Carcinoma

United States
Repertoire Immune Medicines

Terminated

This SCR-103 Protocol Will Permit Sites to Proactively Assess TAA, HLA and HPV-16 Status in Patients With Selected Solid Tumors to Determine Suitability for Repertoire Immune Medicines Treatment Protocols.

Melanoma | Head and Neck Cancer | HPV-Related Malignancy | Melanoma (Skin) | HPV-Related Carcinoma | HPV-Related Cervical Carcinoma | HPV Positive Oropharyngeal Squamous Cell Carcinoma | Lung Cancer, Nonsmall Cell

United States
AC Immune SA

Withdrawn

A Study of ACI-24 in Adults With Down Syndrome

Down Syndrome
Intervene Immune, Inc.

Recruiting

Thymus Regeneration, Immunorestoration, and Insulin Mitigation Extension Trial (TRIIM-X)

Immunosenescence | Epigenetic Aging

United States
Immune-Onc Therapeutics

Active, not recruiting

Dose-Escalation and Dose-Expansion Study of IO-202 and IO-202+Pembrolizumab in Solid Tumors

Solid Tumor, Adult

United States
Immune Biosolutions Inc

Completed

Phase 1/2 Study to Evaluate the Efficacy and Safety of Inhaled IBIO123 in Participants With Mild to Moderate COVID-19 Illness

COVID-19

South Africa, Brazil
Smart Immune SAS

Recruiting

Safety and Efficacy of SMART101 in Adult Patients With Hematological Malignancies After Haploidentical HSCT With Post-transplant Cyclophosphamide

Hematological Malignancies

France
Immune-Onc Therapeutics

Recruiting

Dose Confirmation and Dose Expansion Phase 1 Study of IO-108 and IO-108 + Anti-PD-1 in Solid Tumors

Advanced Solid Tumor

China
Smart Immune SAS

Recruiting

Safety and Efficacy of SMART101 in Pediatric and Adult Patients With Hematological Malignancies After T Cell Depleted Allo-HSCT

Hematological Malignancies

United States
Immune Biosolutions Inc

Completed

Phase 1&2 Study to Evaluate the Safety & Efficacy of Inhaled IBIO123 in Severe COVID-19 Illness

COVID-19

Ukraine, South Africa
University of Wisconsin, Madison
Immunex Corporation

Completed

A Pilot Study to Examine the Feasibility and Effect of Tumor Necrosis Factor (TNF) Inhibition on HIV Disease

HIV Infections

United States
Immunic AG

Active, not recruiting

MRI Trial to exPlore the efficAcy and Safety of IMU-838 in Relapsing Remitting Multiple Sclerosis (EMPhASIS) (EMPhASIS)

Relapsing-Remitting Multiple Sclerosis (RRMS)

Poland, Bulgaria, Romania, Ukraine
NImmune Biopharma

Terminated

Efficacy and Safety of Oral BT-11 in Moderate to Severe Crohn's Disease

Crohn's Disease

United States
NImmune Biopharma

Completed

Safety Tolerability and Pharmacokinetics of Oral NIM-1324 in Healthy Adult Male and Female Volunteers

Normal Healthy Volunteers

Australia
NImmune Biopharma

Withdrawn

Safety and Efficacy of Oral BT-11 in Crohn's Disease Patients With Moderate to Severe Disease

Crohn's Disease
Immutep S.A.S.

Withdrawn

A Study in Hormone Receptor-positive Metastatic Breast Carcinoma Patients to Test a New Schedule of Efti (IMP321, Eftilagimod Alpha) as Adjunctive to a Weekly Treatment Regimen of Paclitaxel (AIPAC-002)

Metastatic Breast Cancer
Immune Oncology Research Institute

Recruiting

Continuous Infusion of First-Generation 5-HT3 Receptor Antagonists in Combination With Dexamethasone

Pediatric Cancer

Armenia
Natural Immune Systems Inc

Recruiting

Clinical Proof-of-concept Study on Immune Surveillance and Alertness

Immune Surveillance

United States
Natural Immune Systems Inc

Recruiting

Antioxidant Bioavailability

Pharmacokinetics

United States
Immune System Regulation AB

Unknown

Efficacy and Safety of GnRH Analogue Triptorelin for HIV-1 Reservoir Reduction in ART Treated HIV-1 Infected Patients

HIV-1-infection

Sweden, Germany
Immune System Key Ltd

Withdrawn

A Phase 2a, Open-Label, Two Stage Study of Nerofe or Nerofe With Doxorubicin in Subjects With AML or MDS

Myelodysplastic Syndromes | Acute Myelogenous Leukemia

Israel
Immune Design
Genentech, Inc.

Terminated

Study to Compare the Safety and Efficacy of CMB305 With Atezolizumab to Atezolizumab Alone in Participants With Sarcoma (IMDZ-C232/V943A-002)

Sarcoma | Myxoid/Round Cell Liposarcoma | Liposarcoma | Synovial Sarcoma | Recurrent Adult Soft Tissue Sarcoma | Metastatic Sarcoma | Locally Advanced Sarcoma

United States
Natural Immune Systems Inc

Completed

Nutraceutical Support of Fatigue Reduction, Improved Physical, Mental & Cognitive Function and Mitochondrial Function

Fatigue

United States
Natural Immune Systems Inc

Completed

Evaluation of Activity Levels, Inflammatory Markers, and Overall Wellness. (114-012)

Range of Motion

United States
Natural Immune Systems Inc

Completed

CytoQuel: Clinical Documentation on Effects on Chronic Pain, Wellness, and Reduction of Inflammatory Markers

Pain

United States
Immune Targeting Systems Ltd

Completed

Safety and Reactogenicity of a H1N1 Influenza Challenge Virus in Healthy Volunteers

Influenza A

Belgium
Immutep S.A.S.

Recruiting

Study in Metastatic Breast Cancer Patients Receiving Eftilagimod Alpha or Placebo in Combination With Paclitaxel Chemotherapy (AIPAC-003)

Breast Carcinoma

Spain, United States, Belgium
Immunis, Inc.

Recruiting

Safety and Tolerability of IMMUNA(IMM01-STEM) in Patients With Muscle Atrophy Related to Knee Osteoarthritis.

Muscle Atrophy

United States

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