Clinical Trials Sponsored by Institut Gustav Roussy

Total 292 results

Gustave Roussy, Cancer Campus, Grand Paris

Recruiting

Lymphocyte Support to SBRT in Patients With Oligo-metastatic Solid Cancer (LySATRA)

Solid Tumor, Adult | Oligometastatic Disease

France
Gustave Roussy, Cancer Campus, Grand Paris

Recruiting

Long Term Brain Toxicity of Chemotherapy in Patients Treated for a Bone TumorDuring Childhood or Adolescence (OSE)

Adults Treated During Childhood or Adolescence for a Malignant Bone Tumor (Osteosarcoma and Ewing Sarcoma)

France
Gustave Roussy, Cancer Campus, Grand Paris

Recruiting

Gustave Roussy Cancer Profiling (STING)

Solid Tumor, Unspecified, Adult

France
Gustave Roussy, Cancer Campus, Grand Paris

Recruiting

Safety and Efficacy of AsiDNATM, a DNA Repair Inhibitor, Administered Intravenously in Addition to PARP Inhibitors in Patients With Relapsed Platinum Sensitive Ovarian Cancer Already Treated With PARP Inhibitors Since at Least 6 Months (REVOCAN)

Ovarian Cancer

France
Gustave Roussy, Cancer Campus, Grand Paris

Recruiting

IMRT and Primary Transoral Surgery in the Treatment of Squamous Cell Carcinomas (TORPHYNX)

Squamous Cell Carcinoma

France
Gustave Roussy, Cancer Campus, Grand Paris

Recruiting

Nivolumab for Pediatric and Adult Relapsing/Refractory ALK+, for Evaluation of Response in Patients With Progressive Disease (Cohort 1) or as Consolidative Immunotherapy in Patients in Complete Remission After Relapse (Cohort 2) (NIVO-ALCL)

Relapsing/Refractory ALK+ Anaplastic Large Cell Lymphoma

France, Denmark, Netherlands
Gustave Roussy, Cancer Campus, Grand Paris

Recruiting

Neoadjuvant Treatment Associated With Maintenance Therapy by Anti-PD1 Immunotherapy in Patients With Resectable Head and Neck Mucosal Melanoma (IMMUQ)

Head and Neck Mucosal Melanomas

France
Gustave Roussy, Cancer Campus, Grand Paris

Recruiting

Sequential Analysis in Patients With an Hemopathy (S-HEMO)

Hemopathy

France
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Atezolizumab as Induction Therapy in Non-small Cell Lung Cancer (PRINCEPS)

Nonsmall Cell Lung Cancer

France
Gustave Roussy, Cancer Campus, Grand Paris

Active, not recruiting

Optimization of an Online Stepwise Therapeutic Device Based on a Cognitive-behavioral Approach for Cancer Patients With Insomnia (Sleep-4-All-2)

Cancer | Insomnia

France
Gustave Roussy, Cancer Campus, Grand Paris

Completed

A Trial Evaluating the Safety & Efficacy of Intra-Tumoral Ipilimumab in Combination With Intra-venous Nivolumab in Patients With Metastatic Melanoma (NIVIPIT)

Stage III/IV Melanoma

France
Gustave Roussy, Cancer Campus, Grand Paris

Active, not recruiting

Intratumoral Tilsotolimod, a TLR-9 Agonist, Together With Intratumoral Ipilimumab and Intravenous Nivolumab in Patients With Advanced Cancers (PRIMO)

Advanced Cancer

France
Gustave Roussy, Cancer Campus, Grand Paris

Active, not recruiting

Pembrolizumab in Combination With Bevacizumab and Pegylated Liposomal Doxorubicin in Patients With Ovarian Cancer (PEMBOV)

Ovarian Cancer

France
Gustave Roussy, Cancer Campus, Grand Paris

Withdrawn

Basket Trial for Combination Therapy With Durvalumab (Anti-PDL1) (MEDI4736) and Tremelimumab (Anti-CTLA4) in Patients With Metastatic Solid Tumors (MATILDA)

Metastatic Colorectal Cancer | Triple Negative Breast Cancer | Esophageal Adenocarcinoma | Prostate Adenocarcinoma | Stomach Adenocarcinoma
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Axillary Reverse Mapping Using Near-infrared Imaging in Invasive Breast Cancer: Predictors of Nodal Positivity (ARMONIC)

Breast Cancer

France
Gustave Roussy, Cancer Campus, Grand Paris

Withdrawn

Study of Intratumoral Ipilimumab and TLR4 Agonist GLA-SE in Combination With Systemic Nivolumab and Chemotherapy (ISILI)

Colorectal Cancer Metastatic

France
Gustave Roussy, Cancer Campus, Grand Paris

Completed

A Study to Select Rational Therapeutics Based on the Analysis of Matched Tumor and Normal Biopsies in Subjects With Advanced Malignancies (WINTHER)

Metastatic Cancer

France
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Efficacy of Radium 223 in Radioactive Iodine Refractory Bone Metastases From Differentiated Thyroid Cancer (RAD-THYR)

Thyroid Cancer

France
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Trial Comparing Trabectedin to the Best Supportive Care in Patients With Sarcoma (TSAR)

Soft Tissue Sarcoma

France
Gustave Roussy, Cancer Campus, Grand Paris

Unknown

Study of a Simplified Geriatric Evaluation Performed by Oncologists Prior to Cancer Treatment by Radiotherapy or Chemotherapy in Subjects Aged 70 Years or Older With Inoperable Squamous Cell Cancer of the Head and Neck (ELAN-ONCOVAL)

Inoperable Squamous Cell Cancer of the Head and Neck

France
Gustave Roussy, Cancer Campus, Grand Paris

Unknown

Evaluation of HPV OncoTect ™ for the Etiological Diagnosis of HPV-induced Oropharyngeal Cancers (HPV OncoTect™)

Oropharyngeal Cancer

France
Gustave Roussy, Cancer Campus, Grand Paris

Unknown

Trial of Superiority of Stereotactic Body Radiation Therapy in Patients With Breast Cancer (STEREO-SEIN)

Breast Cancer

France
Gustave Roussy, Cancer Campus, Grand Paris

Unknown

Trial Evaluating Maintenance Olaparib in Patients With Platinum-sensitive Advanced Non-small Cell Lung Cancer (PIPSeN)

Non Small Cell Lung Cancer

France
Gustave Roussy, Cancer Campus, Grand Paris

Unknown

Optimized Angiomammography and Comparison With Standard Angiomammography (OPTIAM)

Patients for Whom an Angiomammogram Examination is Requested Whether Its Indication

France
Gustave Roussy, Cancer Campus, Grand Paris

Unknown

Trial Comparing Simple Follow-up to Exploratory Laparotomy Plus "in Principle" (Hyperthermic Intraperitoneal Chemotherapy) HIPEC in Colorectal Patients (ProphyloCHIP)

Colorectal Cancer With a Resected Minimal Synchronous PC | Ovarian Metastases | Tumour Rupture in the Abdominal Cavity

France
Gustave Roussy, Cancer Campus, Grand Paris

Unknown

Multicenter Phase II Study of Sentinel Node Detection in Squamous Cell Carcinoma T1-T2N0 of the Oropharynx Treated With Radiotherapy and Larynx Treated by Surgery, Laser or Robot (GS-OROPHARYNX)

Head and Neck Cancer

France
Gustave Roussy, Cancer Campus, Grand Paris

Terminated

Comparison of Dosimetry After rhTSH or Withdrawal of Thyroid Hormone in Metastatic or Locally Advanced Thyroid Cancer (DOSIMETA)

Thyroid Cancer | Metastases

France
Gustave Roussy, Cancer Campus, Grand Paris

Completed

A Phase Ib Study of the Safety, Tolerability and Efficacy of LY2780301 in Combination With Gemcitabine (INPAKT)

Solid Tumors and Non-Hodgkin's Lymphoma

France
Gustave Roussy, Cancer Campus, Grand Paris

Unknown

Identification of Marker of Primary or Acquired Resistance to Anti Tumorous Treatment (MSN)

Melanoma | Small Cell Lung Cancer | Non Small Cell Lung Cancer

France
Gustave Roussy, Cancer Campus, Grand Paris

Unknown

Iatrogenic Effects of Treatment for Childhood Cancer Constitution of a Biological Samples Bank (BIO-F)

Paediatric Malignancies

France
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Intra-arterial Hepatic Bevacizumab and Systemic Chemotherapy (BEVIAC)

Colorectal Neoplasms

France
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Randomized Phase II Study to Assess PD 0332991 in Breast Cancer (POP)

Untreated Operable Early Breast Cancer

France
Gustave Roussy, Cancer Campus, Grand Paris

Unknown

Peripheral Primitive Fibromatosis (WS-RT Fibro)

Peripheral Primitive Fibromatosis

France
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Dose Escalation of Velcade Daily Dose in Patients With Solid Tumors (VELDAY)

Advanced or Metastatic Solid Tumors

France
Gustave Roussy, Cancer Campus, Grand Paris

Unknown

Temsirolimus and Cetuximab in Patients With Advanced or Metastatic Solid Tumors (TORERO)

Patients With Advanced or Metastatic Solid Tumors

France
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Assessment of Tumor Vascular Effects of Axitinib With Dynamic Ultrasonography in Patients With Metastatic Colorectal Cancer (AXUS)

Colorectal Carcinoma

France
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Dose Escalation of Cisplatin Hyperthermic Intraperitoneal Chemotherapy After Surgery in Patients With Unresectable Stage IIIC Ovarian, Tube or Peritoneal Primary Adenocarcinoma (CHIPASTIN)

Fallopian Tube Adenocarcinoma | Ovarian Adenocarcinoma | Primary Peritoneal Carcinoma

France
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Study Comparing Isolated Pelvic Perfusion With TNF-α 0.3 mg and Melphalan 1.5 mg/kg Versus Standard Treatment in Patients With Non Resectable, Recurrent Gynaecologic or Digestive Pelvic Cancer

Gynaecologic or Digestive Pelvic Cancer

France
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Temozolomide in Association With Topotecan in Refractory or Relapsed Malignant Tumors in Children and Adolescents

Malignant Tumors | Refractory Tumors

France
Gustave Roussy, Cancer Campus, Grand Paris

Unknown

Intraperitoneal Hyperthermic Chemotherapy in Epithelial Ovarian Carcinoma

Epithelial Ovarian Carcinoma | Figo Stage IIIC

France
Gustave Roussy, Cancer Campus, Grand Paris

Terminated

Treatment of a Cancerous Disease of the Peritoneum With Complete Cytoreductive Surgery and Intraperitoneal Chemohyperthermia

Endocrine Tumors | Colon Tumors | Rectum Tumors | Appendix Tumors | Peritoneum Tumors

France
Gustave Roussy, Cancer Campus, Grand Paris

Terminated

Trial of Docetaxel-Samarium in Patients With Hormone-Refractory Advanced Prostate Cancer

Prostate Cancer

France
Gustave Roussy, Cancer Campus, Grand Paris

Terminated

Randomised Study to Compare the Effect of r-Hu-EPO Administration With Transfusion of Red Blood Cell Concentrates and Also With the Administration of Polyvitamins in Anemic and Tired Patients Presenting a Bad Prognostic in Middle Course

- Medico-Economic Aspects (Evaluation of Medical Costs Related to the Three Strategies and Evaluation of Cost/Efficacy)

France
Gustave Roussy, Cancer Campus, Grand Paris

Unknown

Trial of Gemcitabine, Cisplatin, and Ifosfamide in Patients With Relapsed Non-Seminomatous Germ-Cell Tumors

Germ Cell Tumor

France
Gustave Roussy, Cancer Campus, Grand Paris

Unknown

Trial Comparing Cisplatin With or Without Gemcitabine in Patients With Carcinoma of Unknown Primary

Carcinoma

France
Gustave Roussy, Cancer Campus, Grand Paris

Unknown

Randomized Trial Of Platelet Transfusion Policies After Blood Stem Cells Transplantation In Young Children: Reduction Of Number Of Single Platelet Concentrate Donors Per Child

Children Treated With High-Dose Chemotherapy (HDC) Followed by Haematopoietic Stem Cell Transplantation (HSCT)

France
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Comparison of High-Dose Methotrexate (HDM) Plus Doxorubicin to HDM Plus Etoposide-Ifosfamide in Osteosarcoma Children

Osteosarcoma | Localised High Grade Osteosarcoma of the Limbs

France
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Unmodified Versus Leuko-Reduced Allogeneic Red Blood Cells Transfusion in Cancer Patients

Cancer | Surgery

France
Gustave Roussy, Cancer Campus, Grand Paris

Terminated

Early Tracheotomy Versus Prolonged Endotracheal Intubation in Intensive Care Unit (ICU) Patients

Respiratory Insufficiency

France
Gustave Roussy, Cancer Campus, Grand Paris
Institut Curie

Completed

Standard Neoadjuvant Chemotherapy Versus Genomic Driven Chemotherapy in Patients With Breast Cancer (REMAGUS04)

Breast Cancer

France

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