Clinical Trials Sponsored by Isis Pharmaceuticals

Total 19751 results

ISIS Diabete Service

Unknown

Intensive Versus Standard One Year Monitoring on Glycaemic Control After Initiating CSII in Children With DT1. DEEP Study (DEEP)

Diabetes Mellitus, Type 1 | Pediatric ALL

France
ASIS Corporation

Unknown

ASIS for GAMMAGARD in Primary Immunodeficiency (ASISinPI)

Primary Immunodeficiency

United States
ASIS Corporation

Unknown

ASIS for Botox in Chronic Migraine (ASISinCM)

Chronic Migraine More than15 Days Per Month, and Lasting 4 Hours a Day or Longer.

United States
Fundacion Ibis

Unknown

Telemedicine in HIV Care in Buenos Aires

Telemedicine | HIV-1-infection
ASIS Corporation

Unknown

ASIS for Enbrel in Plaque Psoriasis (ASISinPP)

Plaque Psoriasis.

United States
Laclaree
Iris Pharma

Completed

Pilot Clinical Investigation of Adaptative Eyeglasses for the Correction of Presbyopia (eve-1)

Presbyopia

France
IRIS Media Inc

Completed

ASD Parent Trainer: Online Coaching for Parents of Children With Autism (APT)

Autism Disorder

United States
li nguyen

Unknown

ASIS for Botox in Cervical Dystonia (ASISinCD)

Cervical Dystonia Adults , | Abnormal Head Position and Neck Pain for These 7 Muscle Groups: Splenius,Scalene,Sterno-cleido-mastoid,Levator Scapulae,Semispinalis,Trapezius,and Longissimus.

United States
SIS Medical AG

Unknown

Optimal Lesion Preparation With Non-compliant Balloons Before Implantation Of Bioresorbable Scaffolds (OPreNBiS)

Coronary Artery Disease | Stable Angina | Unstable Angina | Angina

Switzerland
li nguyen

Unknown

ASIS for Botox in Upper Limb Spasticity (ASISinULS)

Upper Limb Spasticity Unilaterally in Adults With History of Stroke | Increased Muscle Tone in Elbow, Wrist, Finger, and Thumb Flexors.

United States
Alexza Pharmaceuticals, Inc.
ISS, Inc.; DSG; Peachtree BioResearch Solutions

Terminated

Study to Evaluate the Efficacy and Safety of Staccato Apomorphine (AZ-009) in Patients With Parkinson's Disease Experiencing OFF Episodes

Parkinson Disease

United States
SIS Medical AG

Suspended

Absorb BVS vs. Drug Coated Balloon for Treatment Of ISR (AbsorbISR)

Coronary Artery Disease | Coronary Restenosis

Switzerland
Loughborough University
Natalia Iris

Recruiting

Understanding the Impact of Physical Activity Calorie Equivalent (PACE) Labelling in Secondary Schools

Eating Behaviour of Discretionary Foods

United Kingdom
Laboratoires Thea
Iris Pharma

Completed

Survey: Evaluation of Ocular Surface Disease Symptoms and Patient Satisfaction With Thealoz® Duo After 84 Days of Daily Treatment

Dry Eye

United Kingdom
Iris Sommer

Unknown

Transcranial Direct Current Stimulation as Treatment for Auditory Hallucinations (tDCS)

Personality Disorders | Psychotic Disorders | Mood Disorders | Stress Disorders, Post-Traumatic | Hearing Disorders

Netherlands
Iris Sommer

Unknown

Understanding Hallucinations (Part II) (UH-2)

Hallucinations

Netherlands
IRIS Media Inc
Spelman College

Completed

Culturally Responsive Stress Reduction: A Mobile Mindfulness Application for African Americans (CRSR) (CRSR)

Behavior

United States
NicOx
Theradis pharma; Iris Pharma

Withdrawn

Efficacy and Safety of Iota-Carrageenan Eye Drops (NCX-4240) (Goldeneye)

Adenoviral Conjunctivitis

Spain
IRIS Research and Development, LLC
Mallinckrodt

Completed

Clinical Impact of Acthar in the Psoriatic Arthritis Patient (CLIPS) (CLIPS)

Psoriatic Arthritis

United States
Ibis Reproductive Health
Marie Stopes International

Unknown

Medical Abortion at Gestational Age of 8 to ≤9 Weeks Versus >9 to ≤12 Weeks

Medical Abortion

Mexico
KCRI
SIS Medical AG

Completed

Optimal Lesion Preparation With Non-compliant Balloons Before Implantation Of Bioresorbable Scaffolds (OPreNBiS)

Coronary Artery Disease | Angina, Stable | Angina, Unstable

Switzerland
Novartis Pharmaceuticals
Chugai Pharmaceutical

Completed

Study of Safety and Efficacy of Letrozole Monotherapy as Second-line Endocrine Therapy in Postmenopausal Patients With Advanced Breast Cancer Who Received Previous Anti-estrogen Treatment

Postmenopausal Women With Advanced Breast Cancer

Japan
Novartis Pharmaceuticals
Chugai Pharmaceutical

Completed

Extension Study of 1.0mg Dose Letrozole Therapy in Postmenopausal Patients With Breast Cancer

Postmenopausal Women With Advanced Breast Cancer

Japan
Novartis Pharmaceuticals
Chugai Pharmaceutical

Completed

Study of High-dose Letrozole Therapy in Postmenopausal Patients With Breast Cancer

Postmenopausal Women With Advanced Breast Cancer

Japan
University Hospital, Clermont-Ferrand
Abbott; Corelab ISIT

Completed

Morphological Parameters of In-stent RESTenosis Assessed and Identified by OCT (RESTO)

In-stent Restenosis

France, Belgium, Switzerland
Santersus AG
ISS AG

Not yet recruiting

Safety, Tolerability and Performance of the NucleoCapture Device in the Reduction of Circulating cfDNA/NETs in Subjects With Sepsis (NUC-CAP)

Sepsis | Respiratory Failure

United Kingdom, Germany, Switzerland
SynDermix AG
ISS AG

Withdrawn

Safety and Efficacy of SDX-3101 for the Treatment of Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP) (SDX-3101)

Chronic Rhinosinusitis Without Nasal Polyps

Germany, Austria, Switzerland
Xiao Jing (Iris) Wang
Mayo Clinic

Enrolling by invitation

Tradipitant for Functional Dyspepsia

Functional Dyspepsia

United States
Wiebe, Ellen, M.D.
Ibis Reproductive Health

Completed

Comparing Methotrexate Followed by Misoprostol to Misoprostol Alone for Early Abortion

Unwanted Pregnancies

Canada
Regeneron Pharmaceuticals
Teva Pharmaceutical Industries, Ltd.

Terminated

Study to Evaluate Arthroplasty Specimens for Osteoarthritis of the Knee and Hip

Osteoarthritis, Knee | Osteoarthritis, Hip

United States, Poland, United Kingdom
Enanta Pharmaceuticals, Inc
Pharmaceutical Research Associates

Completed

Drug-Drug Interaction Study Between EDP-938, Tacrolimus, Dabigatran, Rosuvastatin and Midazolam in Healthy Subjects

RSV Infection

United States
Vertex Pharmaceuticals Incorporated
Tibotec Pharmaceutical Limited

Completed

A Study Evaluating 24-Week and 48-Week Telaprevir-Based Regimen in Treatment Naïve Subjects With Genotype 1 Chronic Hepatitis C Who Achieve an Extended Rapid Viral Response

Hepatitis C

Belgium, United States, Puerto Rico, Netherlands
Regeneron Pharmaceuticals
Teva Pharmaceutical Industries, Ltd.

Completed

To Assess the Patients' Ability to Self-Administer Fasinumab (FACT DEVICE)

Osteoarthritis, Knee | Osteoarthritis, Hip

United States
Alexza Pharmaceuticals, Inc.
Pharmaceutical Research Associates

Unknown

Observational Study Evaluating the Safety of ADASUVE® in Agitation Associated With Schizophrenia or Bipolar I Disorder

Agitation,Psychomotor

United States
Enanta Pharmaceuticals, Inc
Pharmaceutical Research Associates

Completed

Drug-Drug Interaction Study Between EDP-938, Cyclosporine and Prednisone in Healthy Adult Subjects

RSV Infection

United States
Vertex Pharmaceuticals Incorporated
Tibotec Pharmaceutical Limited

Completed

Safety and Efficacy of Telaprevir in Combination With Peginterferon Alfa-2a and Ribavirin in Subjects Co-Infected With Hepatitis C Virus (HCV) and HIV

HIV Infections | Hepatitis C

France, Spain, United States, Germany
Tibotec Pharmaceuticals, Ireland
Tibotec Pharmaceutical Limited

Completed

A Study to Evaluate Antiviral Activity of Darunavir + Ritonavir in HIV-1 Infected Adolescents (DIONE)

HIV-1 Infection

France, United States, Spain, Ukraine, United Kingdom, Ireland
Laboratoires Thea
Iris Pharma; Axial Biotech, Inc

Completed

Management of Eyelid Disorders by Ophthalmologists in Usual Medical Practice (MEIBUM)

Meibomian Gland Dysfunction | Ocular Surface Disease | Palpebral Pathologies

Germany, Spain
Iris Sommer
Netherlands Brain Foundation

Withdrawn

Effect of Methylphenidate on Connectivity

Attention Deficit Hyperactivity Disorder

Netherlands
Novartis Pharmaceuticals
Pharmaceutical Research Associates

Withdrawn

Pharmacokinetics Study of TNO155 in Participants With Mild, Moderate, or Severe Renal Impairment Compared to Matched Healthy Participants

Renal Impairment
Novartis Pharmaceuticals
Pharmaceutical Research Associates

Withdrawn

Pharmacokinetics of TNO155 in Participants With Mild, Moderate, or Severe Hepatic Impairment Compared to Matched Healthy Participants

Hepatic Impairment
Regeneron Pharmaceuticals
Teva Pharmaceutical Industries, Ltd.

Completed

Study to Determine the Safety and the Efficacy of Fasinumab Compared to Placebo and Nonsteroidal Anti-inflammatory Drugs (NSAIDs) for Treatment of Adults With Pain From Osteoarthritis of the Knee or Hip (FACT OA2)

Osteoarthritis, Knee | Osteoarthritis, Hip

United States
Enanta Pharmaceuticals, Inc
Pharmaceutical Research Associates

Completed

A Study of EDP-514 in Patients With Chronic Hepatitis B Virus Infection Who Are Not Currently on Treatment

Chronic HBV Infection

Hong Kong, Taiwan
Regeneron Pharmaceuticals
Teva Pharmaceutical Industries, Ltd.

Terminated

Evaluate the Efficacy and Safety of Fasinumab in Patients With Moderate-to-Severe Chronic Low Back Pain and Osteoarthritis of the Hip or Knee (FACT CLBP 1)

Osteoarthritis | Chronic Low Back Pain

United States
Enanta Pharmaceuticals, Inc
Pharmaceutical Research Associates

Completed

Drug-Drug Interaction Study Between EDP-938, Itraconazole, Rifampin, and Quinidine in Healthy Subjects

RSV Infection

United States
Melior Pharmaceuticals
Bukwang Pharmaceutical, Co., Ltd.

Completed

Adult Subjects With Uncontrolled Type 2 Diabetes

Type 2 Diabetes

United States
Tibotec Pharmaceuticals, Ireland
Tibotec Pharmaceutical Limited

Completed

A Safety Study to Evaluate the Antiviral Activity of Darunavir in Combination With Ritonavir in HIV 1 Infected Children

Human Immunodeficiency Virus 1

South Africa, Argentina, Brazil, India, Kenya
Vertex Pharmaceuticals Incorporated
Tibotec Pharmaceutical Limited

Completed

A Study to Examine the Effects of Telaprevir on the Pharmacokinetics of Cyclosporine and Tacrolimus in Healthy Adults

Hepatitis C

United States
Regeneron Pharmaceuticals
Teva Pharmaceutical Industries, Ltd.

Completed

Long-Term Safety and Efficacy Study of Fasinumab in Patients With Pain Due to Osteoarthritis (OA) of the Knee or Hip (FACT LTS & OA)

Osteoarthritis of the Knee or Hip

United States, Bulgaria, Chile, Colombia, Denmark, Estonia, Germany, Hong Kong, Hungary, Italy, Lithuania, Mexico, Peru, Poland, Romania, Russian Federation, South Africa, Spain, Sweden, Ukraine, United Kingdom
Regeneron Pharmaceuticals
Teva Pharmaceutical Industries, Ltd.

Completed

Study to Evaluate the Effects of Fasinumab on Peripheral Nerve Function in Patients With Pain Due to Osteoarthritis of the Hip or Knee

Osteoarthritis, Knee | Osteoarthritis, Hip

United States, Poland, United Kingdom

Clinical Trials Sponsored by Isis Pharmaceuticals

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Ethiopia

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Rare Diseases

Drug Interventions

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