Clinical Trials Sponsored by Keystone Heart

Total 6804 results

Keystone Heart

Completed

The REFLECT Trial: Cerebral Protection to Reduce Cerebral Embolic Lesions After Transcatheter Aortic Valve Implantation

Symptomatic Aortic Stenosis

United States, Netherlands, Germany, Italy
Keystone Heart

Completed

A Study to Evaluate the Neuro-embolic Consequences of TAVR

Aortic Valve Stenosis

United States
Keystone Heart

Completed

DEFLECT I: Keystone Heart Embolic Deflection Trial

Aortic Stenosis
Keystone Heart

Completed

DEFLECT III: A Prospective, Randomized Evaluation of the TriGuard™ HDH Embolic Deflection Device During TAVI (TAVI)

Aortic Valve Stenosis

Netherlands, Israel, United Kingdom, Germany, France, Italy
Keystone Heart

Completed

DEFLECT II: A Study to Evaluate the Safety and Performance of the TriGuard™HDH in Patients Undergoing TAVR

Aortic Valve Stenosis

Netherlands
Keystone Rehabilitation Systems

Unknown

The Effects of Thoracic Spine Manipulation in Individuals With Non-traumatic Cervical Pain

Neck Pain | Cervical Pain

United States
Keystone Rehabilitation Systems

Unknown

Verbalization in Patients With Non-specific Low Back Pain and Central Sensitization

Low Back Pain | Central Sensitization | Pain Catastrophizing

United States
Crozer-Keystone Health System

Recruiting

CyberKnife Dose Escalation Prostate Cancer Trial (CK-DESPOT)

Prostate Cancer | Prostate Adenocarcinoma | Prostate Neoplasm

United States
Crozer-Keystone Health System

Unknown

Reactor Thoracostomy (UNCUT)

Pneumothorax | Hemothorax
Gemstone Biotherapeutics

Unknown

Briagen Observational Study (BOS)

Mohs Surgery

United States
Medstone International

Terminated

Lithotripsy for the Treatment of Gallstones

Cholelithiasis

United States
Wockhardt
Clinartis, LLC; Keystone Bioanalytical, Inc.

Completed

Safety, Tolerability, and Pharmacokinetics of Multiple Doses of Intravenous Nafithromycin

Healthy

United States
University of Mississippi Medical Center
Keystone Pharmacy

Recruiting

Evaluating the Healing of Diabetic Foot Ulcers With Compounded Anti-Infective Irrigation Therapy

Diabetic Foot Ulcer

United States
Reistone Biopharma Company Limited

Recruiting

A Phase 3 Study to Investigate the Efficacy and Safety of SHR0302 With Moderately to Severely Active Ulcerative Colitis

Ulcerative Colitis

China, United States, Georgia, Poland, Ukraine
Reistone Biopharma Company Limited

Active, not recruiting

Evaluate the Efficacy and Safety of SHR0302 in Adult Patients With Severe Alopecia Areata

Alopecia Areata

China
Reistone Biopharma Company Limited

Active, not recruiting

Evaluate the Efficacy and Safety of Topical SHR0302 Ointment in Patients With Mild-to-Moderate Atopic Dermatitis (MARBLE-23)

Atopic Dermatitis

China
Reistone Biopharma Company Limited

Completed

An Open Label Study of the Effects of SHR1459 in NMOSDs Patients

Neuromyelitis Optica Spectrum Disorders

China
Reistone Biopharma Company Limited

Completed

A Phase II Study in Patients With Moderate to Severe Active Crohn's Disease

Crohn's Disease

China, Poland, Ukraine, United States
Reistone Biopharma Company Limited

Terminated

Assess the Efficacy and Safety of SHR0302 Ointment in Adult Patients With Vitiligo

Vitiligo

China
Reistone Biopharma Company Limited

Completed

A Phase II Study in Patients With Moderate to Severe Active Ulcerative Colitis.

Ulcerative Colitis

China, Poland, Ukraine, United States, Puerto Rico
Reistone Biopharma Company Limited

Completed

A Phase II Study in Adult Patients With Moderate to Severe Atopic Dermatitis

Atopic Dermatitis

China
Reistone Biopharma Company Limited

Completed

A Phase II Study in Patients With Alopecia Areata

Alopecia Areata

China, Australia, United States
Reistone Biopharma Company Limited

Active, not recruiting

Evaluate the Efficacy and Safety of SHR1459 Tablets in Patients With Primary Membranous Nephropathy

Primary Membranous Nephropathy

China
Reistone Biopharma Company Limited

Completed

Evaluate Efficacy and Safety of Oral SHR0302 in Subjects Aged 12 Years and Older With Moderate to Severe Atopic Dermatitis

Atopic Dermatitis

China, Canada
Livzon Pharmaceutical Group Inc.
Palm Beach CRO; Keystone Bioanalytical, Inc.

Completed

Single-dose Escalation Study of SQ-001 Infusion to Characterize the PK Profiles of Major Sentinel Compounds in Healthy Adult Volunteers in US

Solid Tumor Refractory to Standard Therapy

United States
Keystone Nano, Inc
Milton S. Hershey Medical Center; University of Virginia

Not yet recruiting

Study of C6 Ceramide NanoLiposome (CNL) in Patients With Relapsed/Refractory Acute Myeloid Leukemia (KNAN2001)

Acute Myeloid Leukemia, in Relapse | Acute Myeloid Leukemia, Refractory

United States
Keystone Nano, Inc
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

Ceramide NanoLiposome in Patients With Advanced Solid Tumors

Carcinoma | Cancer | Solid Tumors | Tumor

United States
Keystone Dental, Inc.
Aptiv Solutions; Pirkka Nummikoski, DDS, MS; CadBlu North (Hastings, MN)

Unknown

Five Year Survival Study Evaluating the Genesis Dental Implant System (Genesis Dental)

Dental Implants

United States
Crozer-Keystone Health System
Saint Peters University Hospital; Community Medical Center, Toms River, NJ

Completed

Immunotherapy SBRT Sensitization of the Programmed Death-1 (PD-1) Effect (I-SABR)

Non Small Cell Lung Cancer | Metastatic Nonsmall Cell Lung Cancer

United States
Ambry Genetics
Crozer-Keystone Health System; St. Joseph Hospital of Orange; The Saratoga Hospital

Completed

COVID-19 and SARS-CoV-2 Detection in Saliva

RNA Virus Infections

United States
Boston Children's Hospital
Evan's Heart Fund; Mend a Heart Foundation; Matthew Hearts of Hope Foundation

Completed

Fontan Imaging Biomarkers (FIB) Study (FIB)

Congenital Heart Disease | Single-ventricle

United States
Felicia Cosman, MD
Crozer-Keystone Health System; Radius Health, Inc.

Recruiting

Abaloparatide Added to Ongoing Denosumab vs Continued Denosumab Alone

Osteoporosis, Postmenopausal

United States
Heart Initiative

Recruiting

Effect of Short-term Prednisone Therapy on C-reactive Protein in Patients With Acute Heart Failure (CORTAHF)

Acute Heart Failure

Armenia
Minneapolis Heart Institute Foundation
Minneapolis Heart Institute; Twin Cities Heart Foundation

Terminated

Radiation Following Percutaneous Balloon Aortic Valvuloplasty to Prevent Restenosis (RADAR)

Aortic Valve Stenosis

United States
German Heart Institute
The German Heart Foundation

Unknown

Comparison of Different Frailty Assessment Tools

Heart Failure

Germany
Heart Care Foundation

Recruiting

BRING-UP 3 Heart Failure (BRING-UP3HF)

Heart Failure

Italy
InCor Heart Institute

Recruiting

Serum Concentration of Endogenous Estrogens and Sirtuin-1 After Administration of Atorvastatin and Quercetin:

Coronary Artery Disease | Menopause

Brazil
Montreal Heart Institute

Not yet recruiting

Multidisciplinary Approach for High-risk Patients Leading to Early Diagnosis of Canadians With Heart Failure (MAPLE-CHF)

Heart Failure

Canada
InCor Heart Institute

Recruiting

The Effects of Resveratrol on Sirtuins and Apoptosis Biomarkers (RE-AGES)

Coronary Artery Disease | Menopause | Endothelial Dysfunction

Brazil
Montreal Heart Institute

Recruiting

COLchicine and Non-enteric Coated Aspirin in the Cardiovascular Outcomes Trial of Patients With Type 2 Diabetes (COLCOT-T2D)

Cardiovascular Diseases | Diabete Type 2

Canada
Montreal Heart Institute

Recruiting

Home-based Heat Therapy for Type 2 Diabetes

Diabetes Mellitus, Type 2 | Heat Exposure

Canada
German Heart Institute

Recruiting

Validation of a Non-invasive Assessment of Central Venous Oxygen Saturation by Using MRI

Heart Failure

Germany
Montreal Heart Institute

Recruiting

Impact of FDG-PET/CT on Management of Patients With Native Valve Infective Endocarditis (PET-NAVIE)

Infective Endocarditis | Native Valve Endocarditis

Canada
InCor Heart Institute

Recruiting

PREemptive Analgesia With preGABAlin in HEART Surgery (PREGABA-HEART)

Postoperative Pain

Brazil
American Heart Association

Recruiting

Get With The Guidelines-Heart Failure Registry

Heart Failure

United States
Heart Care Foundation

Active, not recruiting

EmploYEd Antithrombotic Therapies in Patients With Acute Coronary Syndromes HOspitalized in iTalian CCUs (EYESHOT-2)

Acute Coronary Syndrome

Italy
Montreal Heart Institute

Enrolling by invitation

Cardiac Rehabilitation in Congenital Heart Disease: Effects on Brain and Cognitive Functions (CongeNIRS)

Congenital Heart Disease | Congenital Heart Defects

Canada
Montreal Heart Institute

Completed

Feasibility of Prediabetes Remission in Adults With Coronary Heart Disease (DIABEPIC1)

Prediabetic State | Coronary Heart Disease | Healthy Lifestyle | Remission

Canada
Montreal Heart Institute

Completed

Sauna Bathing to Improve Vascular Health of Adults With Heart Disease

Coronary Artery Disease

Canada
Heart Care Foundation

Completed

Left Ventricular DYsfunction in DiAbetes (DYDA)

Heart Diseases | Diabetes Mellitus, Type 2 | Left Ventricular Dysfunction

Italy

Clinical Trials Sponsored by Keystone Heart

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Iran

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations