Clinical Trials Sponsored by LSHTM

Total 49 results

MRC/UVRI and LSHTM Uganda Research Unit

Unknown

HIV PrEP Priming of Immune Effectors (PREPPIE)

HIV-1 Infections

Uganda
MRC/UVRI and LSHTM Uganda Research Unit

Recruiting

Safety and Immunogenicity of LNP-nCOV saRNA-02 Vaccine Against SARS-CoV-2, the Causative Agent of COVID-19 (COVAC-Uganda)

COVID-19

Uganda
University of Oxford
MRC/UVRI and LSHTM Uganda Research Unit

Completed

A Study to Assess the New Candidate Rift Valley Fever Virus Vaccine in Healthy Adults

Rift Valley Fever | RVF

Uganda
MRC/UVRI and LSHTM Uganda Research Unit
Medical Research Council

Unknown

Cotrimoxazole Prophylaxis Cessation Study Among Stabilized HIV-Infected Adult Patients on HAART in Entebbe, Uganda (CCS)

HIV Infections

Uganda
MRC/UVRI and LSHTM Uganda Research Unit
Janssen Pharmaceuticals

Recruiting

Improving HIV-1 Control in Africa With Long Acting Antiretrovirals (IMPALA)

HIV-1-infection

South Africa, Kenya, Uganda
MRC/UVRI and LSHTM Uganda Research Unit
International AIDS Vaccine Initiative

Recruiting

Feasibility of Identifying, Enrolling and Following Acute and Early HIV-1 Infected Individuals. (KILGORIS)

Acute Human Immunodeficiency Virus Type I Infection

Uganda
University of Oxford
MRC/UVRI and LSHTM Uganda Research Unit

Completed

Trial to Investigate the Effect of Schistosoma Mansoni Infection on the Response to Vaccination With MVA85A in BCG-vaccinated African Adolescents (TB036)

Tuberculosis

Uganda
University of Oxford
MRC/UVRI and LSHTM Uganda Research Unit

Recruiting

Assessment of Safety and Immunogenicity of R21/Matrix-M™ in African Children Living With HIV

Malaria

Uganda
University of Oxford
MRC/UVRI and LSHTM Uganda Research Unit

Completed

EMaBS TB Vaccine Study

Safety | Immunogenicity

United Kingdom, Uganda
MRC/UVRI and LSHTM Uganda Research Unit
Ministry of Health, Uganda

Recruiting

Addressing Medium- to Long-term EBOLA Associated Psychological Distress and Psychosocial Problems in Central Uganda (Ebola+D)

Ebola Virus Disease

Uganda
Armauer Hansen Research Institute, Ethiopia
World Health Organization; Addis Ababa University; LSHTM,UK

Completed

Safety, Immunogenicity and Reactogenicity Trial of Mencevax ACW135 Vaccine (ETH-TVT)

Meningococcal Meningitis

Ethiopia
Epicentre
Kenya Medical Research Institute; LSHTM; Universite Abdou Moumouni de Niamey UAM

Active, not recruiting

Mass Campaigns With Fractional Dose Pneumococcal Vaccines in Sub-Saharan Africa (fPCV) (fPCV)

Pneumococcal Carriage

Niger
MRC/UVRI and LSHTM Uganda Research Unit
London School of Hygiene and Tropical Medicine

Completed

The Effectiveness of a Counselling Intervention on the Uptake of HIV Care Services Among HIV Infected Patients in Uganda

HIV

Uganda
London School of Hygiene and Tropical Medicine
MRC/UVRI and LSHTM Uganda Research Unit; Makerere University

Completed

Kangaroo Mother Care Before Stabilisation Amongst Low Birth Weight Neonates in Africa (OMWaNA)

Preterm Infant | Hypothermia, Newborn | Kangaroo Mother Care | Death; Neonatal

Uganda
St George's, University of London
MRC/UVRI and LSHTM Uganda Research Unit; MU-JHU CARE

Active, not recruiting

Serosurveillance Study of Maternally Derived Anti-GBS Antibody (ProGreSs)

Group B Streptococcus Carrier in Childbirth | Group B Streptococcal Infection, Late-Onset | Group B Streptococcal Infection, Early-Onset | Group B Streptococcus Neonatal Sepsis | Group B Strep Infection

Uganda
St George's, University of London
MRC/UVRI and LSHTM Uganda Research Unit; MU-JHU CARE

Completed

Maternal, Neonatal and Infant Outcomes at Kawempe National Referral Hospital (PREPARE)

Group B Streptococcus Carrier in Childbirth | Group B Streptococcal Infection, Late-Onset | Group B Streptococcal Infection, Early-Onset | Group B Streptococcus Neonatal Sepsis | Group B Strep Infection

Uganda
Obafemi Awolowo University
University of Copenhagen; European and Developing Countries Clinical Trials... and other collaborators

Unknown

Assessing to What Extent Dhps-431V Mutation May Influence the Protective Efficacy of IPTp-SP (DEEM-FIT)

Pregnancy Malaria

Nigeria
Leiden University Medical Center
MRC/UVRI and LSHTM Uganda Research Unit; Texas Tech University Health Sciences...

Not yet recruiting

Sm-p80 Schistosomiasis Challenge Study

Schistosomiasis | Schistosoma Mansoni
EuroVacc Foundation
Centre Hospitalier Universitaire Vaudois; MRC/UVRI and LSHTM Uganda Research... and other collaborators

Completed

Evaluation of the Effect of Late Boost on HIV-uninfected Vaccines From EV06 Trial

HIV/AIDS

Uganda
Yaounde Central Hospital
University of Exeter; University of Yaounde 1; MRC/UVRI & LSHTM Uganda Research...

Recruiting

Characteristics of Young-onset Diabetes in Sub-Saharan Africa (YODA) Study (YODA)

Type 1 Diabetes | Diabetes, Autoimmune

Tanzania, Cameroon, South Africa, Uganda
Centers for Disease Control and Prevention
MRC/UVRI and LSHTM Uganda Research Unit; Ministry of Health, Uganda

Unknown

A Clinical Trial to Evaluate the Safety and Efficacy of Ciprofloxacin in the Treatment of Plague in Humans

Plague

Uganda
Johns Hopkins Bloomberg School of Public Health
MRC/UVRI and LSHTM Uganda Research Unit; Rakai Health Sciences Program

Completed

Enhanced Provision of Male Circumcision (MC) for HIV Prevention, Rakai, Uganda

Neonatal Male Circumcision
EuroVacc Foundation
Medical Research Council; Centre Hospitalier Universitaire Vaudois; MRC/UVRI... and other collaborators

Completed

Safety and Immunogenicity Study of a DNA Vaccine Combined With Protein Vaccine Against HIV/AIDS (EV06)

HIV/AIDS

Uganda
University of Oxford
European and Developing Countries Clinical Trials Partnership (EDCTP); Medical...

Recruiting

A Study to Assess the Experimental Malaria Vaccines RH5.2-VLP and R21

Malaria, Plasmodium Falciparum

Gambia
University of California, San Francisco
National Institute of Mental Health (NIMH); MRC/UVRI and LSHTM Uganda Research... and other collaborators

Completed

A Cognitive Behavioral And Structural HIV Prevention Intervention for Young Ugandan Sex Workers (ZETRA)

Sexually Transmitted Infection

Uganda
MRC/UVRI and LSHTM Uganda Research Unit
Department for International Development, United Kingdom; University of Exeter and other collaborators

Recruiting

Identification and Characterization of Diabetes in Low-resource Populations (DOP)

Diabetes

Uganda
Ministry of Health, Uganda
Columbia University; University of Copenhagen; LSHTM; Makerere University, College...

Unknown

Assessing the Effect of Strengthening Referral of Sick Children From the Private Health Sector and Its Impact on Referral Uptake in Uganda.

Malaria
Wawer, Maria J., M.D.
Johns Hopkins Bloomberg School of Public Health; MRC/UVRI and LSHTM Uganda... and other collaborators

Unknown

Trial of Male Circumcision: HIV, Sexually Transmitted Disease (STD) and Behavioral Effects in Men, Women and the Community

HIV Infections | Sexually Transmitted Diseases | Papillomavirus Infections | Gonorrhea | Chlamydia Infections | Syphilis | Genital Herpes | Bacterial Vaginosis

Uganda
London School of Hygiene and Tropical Medicine
Imperial College London; MRC/UVRI and LSHTM Uganda Research Unit; University...

Completed

The Effect of Norethisterone Enanthate on Recurrent Bacterial Vaginosis (HCBV)

HIV | Bacterial Vaginosis

Uganda
University of Oxford
KEMRI-Wellcome Trust Collaborative Research Program; Institut Pasteur; MRC/UVRI... and other collaborators

Completed

Non- Inferiority Fractional-doses Trial for Yellow Fever Vaccine (NIFTY)

Yellow Fever

Kenya, Uganda
MRC/UVRI and LSHTM Uganda Research Unit
Epicentre, Paris, France.; Janssen Pharmaceutica N.V., Belgium; Coalition for... and other collaborators

Completed

ZEBOVAC (Ebola Vaccine Trial, Ad26.ZEBOV/MVA-BN-Filo)

Ebola Virus Disease

Uganda
Centers for Disease Control and Prevention
MRC/UVRI and LSHTM Uganda Research Unit; Ministry of Health, Uganda; Infectious...

Unknown

Immunogenicity of Fractional One-fifth and One-half Doses of Yellow Fever Vaccine Compared to Full Dose in Children 9-23 Months Old

Yellow Fever
Johns Hopkins University
National Institute of Allergy and Infectious Diseases (NIAID); MRC/UVRI and... and other collaborators

Completed

Impact of Peer Health Workers and Mobile Phones on HIV Care

HIV Infections
London School of Hygiene and Tropical Medicine
MRC/UVRI and LSHTM Uganda Research Unit; World Health Organization; Makerere... and other collaborators

Completed

Menstrual Health Interventions and School Attendance Among Ugandans (MENISCUs-2)

Menstrual Health Intervention

Uganda
London School of Hygiene and Tropical Medicine
Guy's and St Thomas' NHS Foundation Trust; Indian Institute of Public Health... and other collaborators

Active, not recruiting

Gestational Diabetes in Uganda and India Improving Screening and Self-management (GUIDES)

Gestational Diabetes

Uganda, India
MRC/UVRI and LSHTM Uganda Research Unit
Karolinska Institutet; University of California, San Francisco; European and... and other collaborators

Recruiting

Improving HIV Prevention Among Adolescent Girls and Young Women (AGYW) in Uganda (PeerPREP)

HIV-1-infection

Uganda
University of California, San Francisco
London School of Hygiene and Tropical Medicine; MRC/UVRI and LSHTM Uganda Research... and other collaborators

Completed

Adjunctive Linezolid for the Treatment of Tuberculous Meningitis (ALTER)

Tuberculosis, Meningeal

Uganda
University of California, San Francisco
London School of Hygiene and Tropical Medicine; National Institute of Mental... and other collaborators

Completed

Improving Uptake and Adherence to HIV Prevention Services With Pre-exposure Prophylaxis (PrEP), HIV Self- Testing and Adherence Support for Very High Risk HIV-negative Young Women Aged 15-24 in Kampala, Uganda (POPPi)

HIV/AIDS

Uganda
Makerere University
MRC/UVRI and LSHTM Uganda Research Unit; Ministry of Health, Uganda; Epicentre; Makerere University Lung Institute and other collaborators

Not yet recruiting

Solidarity/Tokomeza Ebola Trial (TOKOMEZA)

Sudan Ebola Virus Vaccines
MRC/UVRI and LSHTM Uganda Research Unit
Karolinska Institutet; Amsterdam Institute for Global Health and Development; University of Rwanda and other collaborators

Recruiting

East Africa Point of Care Viral Load Study (EAPoC-VL)

HIV | Viral Load | Point of Care Monitoring

Kenya, Uganda
St George's, University of London
Assistance Publique - Hôpitaux de Paris; MRC/UVRI and LSHTM Uganda Research... and other collaborators

Recruiting

Serocorrelate of Protection Against GBS (PREPARE WP3)

Group B Streptococcus Carrier in Childbirth | Group B Streptococcal Infection, Late-Onset | Group B Streptococcal Infection, Early-Onset | Group B Streptococcus Neonatal Sepsis | Group B Strep Infection

France, Italy, Malawi, Netherlands, Uganda, United Kingdom
Makerere University
MRC/UVRI and LSHTM Uganda Research Unit; Makerere University Lung Institute; Directorate... and other collaborators

Recruiting

Clinical Trial of Natural Therapeutics for COVID-19 and Other Acute Respiratory Viral Infections (CONAT)

Acute Respiratory Infection

Uganda
National Institute of Allergy and Infectious Diseases...
MRC/UVRI and LSHTM Uganda Research Unit; Fogarty International Center of the... and other collaborators

Completed

Safety and Effectiveness of the Vaccine ALVAC-HIV vCP205 in HIV-Negative Adult Volunteers in Uganda

HIV Infections

Uganda
University of Oxford
Imperial College London; KEMRI-Wellcome Trust Collaborative Research Program; University of Nairobi and other collaborators

Active, not recruiting

A Study to Test Three Experimental HIV Vaccines in Healthy Adults. (HIV-CORE 006)

HIV-1-infection

Kenya, Uganda, Zambia
MRC/UVRI and LSHTM Uganda Research Unit
London School of Hygiene and Tropical Medicine; Assistance Publique - Hôpitaux... and other collaborators

Not yet recruiting

Implementing Oral (Event-driven and Daily) and Long-acting Pre-Exposure Prophylaxis in Mobile Men in Sub-Saharan Africa (MOBILEMEN)

HIV
National Institute of Allergy and Infectious Diseases...
National Institutes of Health (NIH); Centers for Disease Control and Prevention and other collaborators

Recruiting

Anti-malaria MAb in Kenyan Children

Malaria | Plasmodium Falciparum Infection

Kenya
University College, London
London School of Hygiene and Tropical Medicine; MRC/UVRI and LSHTM Uganda Research... and other collaborators

Recruiting

Long-Acting Treatment in Adolescents (LATA) (LATA)

HIV Infections | Hiv | HIV-1-infection | Paediatric Human Immunodeficiency Virus Infection

Uganda, Zimbabwe, South Africa, Kenya
MRC/UVRI and LSHTM Uganda Research Unit
King's College London; Karolinska Institutet; Gilead Sciences; Imperial College... and other collaborators

Enrolling by invitation

A Combination Efficacy Study in Africa of Two DNA-MVA-Env Protein or DNA-Env Protein HIV-1 Vaccine Regimens With PrEP (PrEPVacc)

HIV Infections

Uganda
Washington State University
National Institute of Allergy and Infectious Diseases (NIAID); Washington University... and other collaborators

Recruiting

RVF and Other Emerging Infectious Diseases in East and Central Africa

Hemorrhagic Fevers, Viral | Rift Valley Fever

Congo, The Democratic Republic of the, Kenya, Tanzania, Uganda

Clinical Trials Sponsored by LSHTM

Sponsors and Collaborators

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