Clinical Trials Sponsored by Legend Healthcare

Total 4638 results

Legend Labz, Inc.

Recruiting

A Sub-Chronic Evaluation of the Safety of Celastrol in Human Subjects

Safety

United States
Legend Labz, Inc.

Recruiting

Effect of Different Ingestion Doses of Celastrol on Human Sperm Motility

Safety Issues

United States
Legend Biotech USA Inc

Recruiting

DLL3-Directed Chimeric Antigen Receptor T-cells in Subjects With Extensive Stage Small Cell Lung Cancer

Small Cell Lung Cancer Extensive Stage | Large Cell Neuroendocrine Carcinoma of the Lung

United States
Legend Biotech USA Inc

Active, not recruiting

Study of CD4-Targeted Chimeric Antigen Receptor T-Cells (CD4- CAR-T) in Subjects With Relapsed or Refractory T-Cell Lymphoma

T-Cell Lymphoma | Peripheral T-Cell Lymphoma Refractory | Cutaneous T-Cell Lymphoma Refractory | Cutaneous T-Cell Lymphoma Recurrent | Peripheral T-Cell Lymphoma Recurrent

United States
Legend Biotech USA Inc

Recruiting

Claudin 18.2-Targeted Chimeric Antigen Receptor T-cells in Subjects With Unresectable, Locally Advanced, or Metastatic Gastric, Gastroesophageal Junction (GEJ), Esophageal, or Pancreatic Adenocarcinoma

Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Gastroesophageal-junction Cancer

United States
Janssen-Cilag Ltd.
Legend Biotech

Completed

A Study of Real-life Current Standards of Care in Patients With Relapsed and/or Refractory Multiple Myeloma Who Received at Least 3 Prior Lines of Therapy Including Proteasome Inhibitor (PI), Immunomodulatory Drug (IMID), and Cluster of Differentiation 38 (CD38) Monoclonal Antibody Treatment (LocoMMotion)

Multiple Myeloma

Belgium, United States, United Kingdom, Italy, Germany, Netherlands, Spain, France, Russian Federation, Poland
HealthCore-NERI
Bayer; Besins Healthcare

Completed

Registry of Hypogonadism in Men (RHyMe)

Male Hypogonadism | Testosterone Deficiency | Androgen Deficiency

Italy, United Kingdom, Spain, Netherlands, Germany, Sweden
Ruijin Hospital
Regend Therapeutics

Not yet recruiting

Follow-up Study of Autologous Transplantation of P63+ Lung Progenitor Cells for Treatment of Bronchiectasis

Bronchiectasis

China
Ruijin Hospital
Regend Therapeutics

Unknown

Autologous Transplantation of Bronchial Basal Cells for Treatment of COPD

COPD
Peking University
Nanjing Legend Biotech Co.

Recruiting

A Study of LCAR-G08 in Subjects With Advanced Gastrointestinal Tumors Expressing Guanylyl Cyclase C (GCC)

Advanced Gastrointestinal Tumors

China
Ruijin Hospital
Regend Therapeutics

Completed

Autologous Transplantation of Bronchial Basal Cells for Treatment of Bronchiectasis

Bronchiectasis

China
Ligand Pharmaceuticals

Completed

A Study of LGD-6972 in Patients With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

United States
Ligand Pharmaceuticals

Completed

Safety and Tolerability Study of Oral LGD-6972 for Type 2 Diabetes Mellitus (L6972-02)

Type 2 Diabetes Mellitus

United States
Ligand Pharmaceuticals

Completed

Compare CE-Budesonide Nasal Solution & Rhinocort Aqua in an EEC Study of AR

Seasonal Allergic Rhinitis

Canada
Ligand Pharmaceuticals

Completed

Compare Captisol-Enabled (CE) Budesonide + Azelastine Nasal Solution and Rhinocort Aqua + Astelin in an Environmental Exposure Chamber (EEC) Study of Allergic Rhinitis

Seasonal Allergic Rhinitis

Canada
Ligand Pharmaceuticals

Completed

A Study To Evaluate The Dose-Related Efficacy and Safety of PS433540 in Subjects With Hypertension

Hypertension

United States
Ligand Pharmaceuticals

Completed

The Prevention Of Postmenopausal Osteoporosis With Lasofoxifene And Cytokine Evaluation (LACE)

Bone Loss

United Kingdom
Shanghai East Hospital
Regend Therapeutics

Completed

Autologous Lung Stem Cell Transplantation in Patients With Interstitial Lung Diseases

Interstitial Lung Diseases

China
Ligand Pharmaceuticals

Completed

Dose Response Study of Lasofoxifene in Postmenopausal Women With Osteoporosis - Japanese Asian Dose Evaluation (JADE)

Osteoporosis

Taiwan, Japan, Korea, Republic of
Shanghai East Hospital
Nanjing Legend Biotech Co.

Terminated

A Clinical Study to Evaluate CAR-T Cell-based Medicinal Product in the Treatment of Advanced Solid Tumors

Solid Tumors, Adult

China
Beijing Boren Hospital
Nanjing Legend Biotech Co.

Terminated

LCAR-T2C CAR-T Cells in Relapsed or Refractory CD4+ T Lymphocyte Tumor

T-cell Leukemia | T Cell Lymphoma

China
Ligand Pharmaceuticals

Completed

Safety, Tolerability, and Efficacy Study of MB07803 Administered to Patients With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

United States
Ligand Pharmaceuticals

Completed

The Effects of Aplindore on the Treatment of Signs and Symptoms of Parkinson's Disease

Early Stage Parkinson's Disease

United States
Ligand Pharmaceuticals

Completed

The Effects of Aplindore on the Treatment of Signs and Symptoms of Restless Legs Syndrome

Restless Legs Syndrome

United States
Ligand Pharmaceuticals

Completed

A Trial to Evaluate the Safety and Efficacy of PS433540 to Treat Hypertension

Hypertension

United States
Ligand Pharmaceuticals

Completed

Postmenopausal Evaluation and Risk-reduction With Lasofoxifene (PEARL) (PEARL)

Osteoporosis

United States, Australia, Canada, Costa Rica, Germany, Russian Federation, France, Croatia, South Africa, Belgium, Japan, India, Spain, United Kingdom, Italy, Egypt, Turkey, Lithuania, Poland, Norway, Estonia, Finland, Denmark, Hong Kong and more
Ligand Pharmaceuticals

Withdrawn

Study of MB07811 in Subjects With Hypercholesterolemia

Hypercholesterolemia

United States
Ligand Pharmaceuticals

Completed

Safety and Tolerability of I.V. Infusion of MB07133 in Patients With Unresectable Hepatocellular Carcinoma

Hepatocellular Carcinoma

United States, Hong Kong, Taiwan
Ligand Pharmaceuticals

Completed

Comparison of Raloxifene and Lasofoxifene - A Randomized, Blinded Study of These Drugs and Placebo on Bone Loss (CORAL)

Osteoporosis

United States
Shanghai East Hospital
Regend Therapeutics

Completed

Clinical Efficacy and Safety of Autologous Lung Stem Cell Transplantation in Patients With Idiopathic Pulmonary Fibrosis

Idiopathic Pulmonary Fibrosis

China
Nanjing Legend Biotech Co.
Janssen Research & Development, LLC

Recruiting

A Study of LCAR-B38M CAR-T Cells, a Chimeric Antigen Receptor T-cell (CAR-T) Therapy Directed Against B-cell Maturation Antigen (BCMA) in Chinese Participants With Relapsed or Refractory Multiple Myeloma (CARTIFAN-1)

Multiple Myeloma

China
American Regent, Inc.

Not yet recruiting

Tralement Versus a Fixed-dose Trace Element Combination Product of Zinc, Copper, and Selenious Acid to Evaluate Product Safety in Pediatric Patients >3 to 17 Years of Age Requiring Long-term Parenteral Nutrition

Manganese Safety in Pediatric Patients
American Regent, Inc.

Completed

Placebo-Controlled Study to Investigate the Efficacy & Safety of Injectafer in the Treatment of RLS

Restless Legs Syndrome (RLS)

United States
American Regent, Inc.

Completed

Comparison of Safety and Efficacy of Intravenous Iron Versus Oral Iron in Chronic Renal Failure Subjects With Anemia

Anemia

United States
Lexent Bio, Inc.

Unknown

Detection of Tumor DNA in Blood Samples From Cancer Patients

Cancer | Tumors

United States
American Regent, Inc.

Completed

Safety and Efficacy of a Hematinic Agent in the Treatment of Postpartum Patients

Postpartum Anemia

United States
American Regent, Inc.

Completed

VIT45 Versus Oral Iron in the Treatment of Anemia in Non-Dialysis Dependent Chronic Kidney Disease

Anemia

United States
American Regent, Inc.

Completed

Safety and Tolerability of a Single Dose of FCM vs. Standard of Care in Treating Iron Deficiency Anemia

Anemia

United States
American Regent, Inc.

Completed

Safety and Tolerability of Ferric Carboxymaltose (FCM) Versus Standard of Care in Treating Iron Deficiency Anemia

Anemia

United States
American Regent, Inc.

Completed

Hypophosphatemia With Ferric Carboxymaltose Vs. Iron Dextran in Iron Deficiency Secondary to Heavy Uterine Bleeding

Iron Deficiency Anemia
American Regent, Inc.

Completed

Taxoprexin Plus Carboplatin Treatment for Advanced Lung Cancer

Non-Small Cell Lung Cancer

United States
American Regent, Inc.

Completed

Comparison of Oral Iron With IV Iron in Patients With Anemia of Chronic Renal Failure Not on Dialysis

Anemia
American Regent, Inc.

Completed

Pharmacokinetic Study of Intravenous Iron Sucrose in Adolescents on Hemodialysis or Peritoneal Dialysis Receiving Epoetin

Anemia
American Regent, Inc.

Completed

Taxoprexin Treatment for Advanced Skin Melanoma

Metastatic Melanoma
American Regent, Inc.

Unknown

Trial to Evaluate the Utility of Serum Hepcidin Levels to Predict Response to Oral or IV Iron and to Compare Safety, Effect on Quality of Life, and Resource Utilization of Injectafer vs Intravenous Standard of Care for the Treatment of IDA in an Infusion Center Setting

Iron Deficiency Anemia (IDA)
American Regent, Inc.

Terminated

Randomized Double Blind Placebo Controlled Trial of Sodium Thiosulfate for the Treatment of Pain Associated With Calcific Uremic Arteriolopath

Calciphylaxis | Calcific Uremic Arteriolopathy

United States
American Regent, Inc.

Completed

Study of the Safety, Tolerability and Analgesic Efficacy of Multiple Doses of Ketorolac Tromethamine (IN) for Postoperative Pain

Postoperative Pain

New Zealand
American Regent, Inc.

Completed

Efficacy and Safety of Intravenous Ferric Carboxymaltose in Pediatric Patients With Iron Deficiency Anemia and Unsatisfactory Response Oral Iron Under Study Protocol 1VIT17044

Iron Deficiency Anemia

United States
American Regent, Inc.

Completed

Safety and Efficacy of Iron Sucrose in Children

Anemia | Chronic Kidney Disease

United States
Lexent Bio, Inc.

Terminated

Detection of Tumor DNA in Blood Samples From Patients With Early Stage Cancer and "Healthy Controls"

Neoplasms, Non-hematologic - Stage I-III

United States

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