Clinical Trials Sponsored by Lpath, Inc

Total 35660 results

Lpath, Inc.

Unknown

Safety Study of iSONEP (Sonepcizumab/LT1009) to Treat Neovascular Age-related Macular Degeneration

Neovascular Age Related Macular Degeneration

United States
Lpath, Inc.

Completed

A Phase 1a, Double-Blind, Placebo-Controlled, Single Ascending Dose Study to Evaluate Lpathomab in Healthy Volunteers

Healthy Subjects

United States
Lpath, Inc.

Completed

Safety Study of ASONEP (Sonepcizumab/LT1009) to Treat Advanced Solid Tumors (ASONEP)

Solid Tumors

United States
Lpath, Inc.

Completed

Efficacy and Safety Study of iSONEP With & Without Lucentis/Avastin/Eylea to Treat Wet AMD (Nexus)

Exudative Age-related Macular Degeneration

United States
Lpath, Inc.

Terminated

A Phase 2 Study of ASONEP™ to Treat Unresectable and Refractory Renal Cell Carcinoma

Renal Cell Carcinoma

United States
Lpath, Inc.
Pfizer

Terminated

iSONEP to Treat Persistent Pigment Epithelial Detachment (PED) in Subjects With Exudative Age-Related Macular Degeneration (AMD) or Polypoidal Choroidal Vasculopathy (PCV) (PED)

Pigment Epithelial Detachment

United States
Bio-Path Holdings, Inc.

Recruiting

A Clinical Trial of BP1002 in Patients With Refractory/Relapsed Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia, in Relapse | Acute Myeloid Leukemia Refractory

United States
Bio-Path Holdings, Inc.

Recruiting

Clinical Trial of BP1001 in Combination With With Venetoclax Plus Decitabine in AML

Acute Myeloid Leukemia (AML)

United States
Bio-Path Holdings, Inc.

Completed

Clinical Trial of BP1001 (L-Grb-2 Antisense Oligonucleotide) in CML, AML, ALL & MDS

Recurrent Adult Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome | Ph1 Positive CML

United States
Bio-Path Holdings, Inc.

Recruiting

BP1001-A in Patients With Advanced or Recurrent Solid Tumors

Fallopian Tube Neoplasms | Carcinoma, Ovarian Epithelial | Solid Tumor | Endometrial Cancer | Peritoneal Cancer | Solid Tumor, Adult

United States
Bio-Path Holdings, Inc.

Recruiting

A Clinical Trial of BP1002 in Patients With Advanced Lymphoid Malignancies

Follicular Lymphoma | Hodgkin Lymphoma | Waldenstrom Macroglobulinemia | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Chronic Lymphocytic Leukemia (CLL) | Small Lymphocytic Lymphoma (SLL) | DLBCL | Cutaneous T-cell Lymphoma (CTCL) | Peripheral T-cell Lymphoma (PTCL)

United States
Bio-Path Holdings, Inc.

Withdrawn

Clinical Trial of BP1001 (Liposomal Grb2 Antisense Oligonucleotide) in Combination With Dasatinib in Patients With Ph + CML Who Have Failed TKI, Ph+ AML, Ph+ MDS

Acute Myeloid Leukemia | Myelodysplastic Syndrome | Chronic Myelogenous Leukemia, Ph1-Positive

United States
PATH Vaccine Solutions

Completed

Phase I Safety Trial of Streptococcus Pneumoniae Whole Cell Vaccine (SPWCV) + Alum in Healthy Adults

Pneumococcal Vaccines

United States
PATH

Completed

Validation of a Diagnostic Test for Glucose-6-phosphate Dehydrogenase (G6PD) Deficiency in Anti-coagulated Blood

G6PD Deficiency

United States
PATH

Completed

Study of Meninigococcal Conjugate Vaccine Containing Serogroups A,C,Y,W and X (MCV5) in Healthy Adults

Meningococcal Vaccines

United States
PATH

Completed

Boosterability of Live Attenuated Japanese Encephalitis (JE) Vaccine in Children Who Have Previously Received Inactivated JE Vaccine

Japanese Encephalitis

Sri Lanka
PATH

Completed

Dose-Finding Study of S.Pneumoniae Whole Cell Vaccine Adsorbed to Alum (PATH-wSP) in Healthy Kenyan Adults and Toddlers

Pneumonia, Pneumococcal

Kenya
PATH

Completed

Stimulating Private Sector Malaria Control (Outgrowers)

Malaria

Zambia
PATH

Completed

Feasibility and Usability of COVID-19 Antigen RDTs in Uganda

COVID-19 Pandemic

Uganda
PATH

Completed

Inactivated Poliovirus Vaccine (IPV) With or Without E.Coli Double Mutant Heat-Labile Toxin (dmLT) Challenge Study in Healthy Adults

Polio

Belgium
PATH

Completed

Phase 3 Study of 10-valent Pneumococcal Conjugate Vaccine (PNEUMOSIL) in Healthy Infants

Pneumonia, Pneumococcal

Gambia
PATH

Completed

A Phase 1 Dose Escalation Study to Examine the Safety of the P2-VP8 Rotavirus Vaccine

Rotavirus Infection

United States
PATH

Completed

Live Attenuated ETEC Vaccine ACE527 With and Without dmLT Adjuvant in Adults

Diarrhea

United States
PATH

Completed

A Study of a Vaccine for Pneumonia in Adults and Toddlers in Kenya

Pneumonia

Kenya
PATH

Completed

Phase I/II Descending Age Study of P2VP8 Subunit Parenteral Rotavirus Vaccine in Healthy Toddlers and Infants

Evaluation of a Rotavirus Vaccine

South Africa
PATH

Withdrawn

Safety, Immunogenicity and Efficacy Study of Inactivated Whole Cell Shigella Flexneri 2a Vaccine With and Without dmLT in Adults

Shigella Sonnei Dysenteries

United States
PATH

Completed

Determining Long-Term Safety and Efficacy of Japanese Encephalitis Vaccine When Given With Measles Vaccine

Encephalitis, Japanese B

Philippines
PATH

Terminated

High Amylose Maize Starch for Treatment of Cholera (RESTORS)

Diarrhea

Bangladesh
PATH

Completed

Immunogenicity of Rotavirus Vaccine

Rotavirus Gastroenteritis

Pakistan
PATH

Not yet recruiting

Developing a Screening Tool for Primary Immunodeficiency Disease (PID) in Pakistan

Primary Immunodeficiency Diseases

Pakistan
PATH

Completed

Safety Study of Inactivated Shigella Whole Cell Vaccine in Adults

Shigellosis

United States
PATH

Completed

Dose Escalating Study of Intramuscular Invaplex[AR-DETOX]

Diarrhea

United States
PATH

Completed

Nasopharyngeal Carriage Study in Healthy Kenyan Toddlers

Pneumococcal Disease

Kenya
PATH

Completed

Safety and Immunogenicity of a 10 Valent Pneumococcal Conjugate Vaccine (SIILPCV10) in Healthy Adults, Toddlers, Infants

Pneumococcal Disease

Gambia
PATH

Completed

Coadministration of Measles-rubella and Rotavirus Vaccines

Measles Antibody Seroconversion | Rubella Antibody Seroconversion | Rotavirus Geometric Mean Titer (GMT) | Rotavirus Immunoglobulin A (IgA) Seropositivity

Bangladesh
PATH

Completed

Lot-to-lot Consistency Trial of Japanese Encephalitis Live Attenuated SA 14-14-2 Vaccine

Japanese Encephalitis

Bangladesh
PATH

Completed

PK Study of iOWH032 in Adult Male/Female Healthy Volunteers & Adult Males With Cholera (PISCES)

Diarrhea | Cholera

Bangladesh
PATH

Completed

Expand Access/Assess Safety and Efficacy of Paromomycin IM Injection for the Treatment of Visceral Leishmaniasis

Visceral Leishmaniasis

India
PATH

Completed

Preliminary Evaluation of a Point-Of-Care Liver Function Test (DFA)

HIV | Tuberculosis | Drug-Induced Liver Injury

Vietnam
PATH

Completed

Performance and Safety Evaluation of an Intradermal Delivery Device

Injections, Intradermal

United States
GlaxoSmithKline
PATH

Completed

A Study to Evaluate the Efficacy, Immunogenicity and Safety in a Sporozoite Challenge Model of a Fractional Booster Dose of GSK Biologicals' Candidate Malaria Vaccine Administered to Previously Vaccinated Healthy Malaria-naïve Adults

Malaria

United States
GlaxoSmithKline
PATH

Completed

A Study to Investigate the Safety and Pharmacodynamics of Repeat Intranasal Administration of the TLR7 Agonist GSK2245035 in Subjects With Respiratory Allergies

Asthma and Rhinitis

Canada
Novavax
PATH

Completed

RSV-F Vaccine Dose Ranging Study in Young Women

Respiratory Syncytial Virus (RSV)

United States
Sanaria Inc.
The PATH Malaria Vaccine Initiative (MVI)

Completed

Clinical Trial of the PfSPZ Vaccine

Plasmodium Falciparum

United States
Bay Path University

Completed

Effectiveness of Occupation-Based Intervention Compared With Therapeutic Exercise for Older Adults With Shoulder OA.

Osteoarthritis Shoulder

United States
PATH
SID Technologies

Completed

Evaluation of the Performance and Safety of Two Intradermal Delivery Devices.

Injections, Intradermal

United States
PATH
University of Rwanda

Completed

Evaluation of Hemoglobin Measurement Tools for Child Anemia Screening in Rwanda

Anemia

Rwanda
PATH
World Health Organization

Completed

Safety and Efficacy Study of Paromomycin to Treat Visceral Leishmaniasis

Visceral Leishmaniasis

India
Valneva Austria GmbH
PATH

Completed

Open-Label Study Assessing The Safety, Immunogenicity and Dose Response of IC47

Pneumococcal Infections

Germany
Shantha Biotechnics Limited
PATH

Withdrawn

Safety and Immunogenicity Study of the Recombinant Human Bovine Reassortant Rotavirus Vaccine in Healthy Indian Infants

Rotavirus Infections

India

3

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