Clinical Trials Sponsored by Lung Cancer Initiative of North Carolina

Total 350 results

Wake Forest University Health Sciences
National Cancer Institute (NCI); Lung Cancer Initiative of North Carolina

Completed

Symptom Burden and Unmet Supportive Care Needs in Lung Cancer Patients Undergoing First or Second Line Immunotherapy

Lung Neoplasm

United States
University of North Carolina, Chapel Hill
North Carolina Diabetes Research Center

Completed

Isoenergetic High Intensity Interval Training and Moderate Intensity Training in Adults With Type I Diabetes (HI1T)

Diabetes Mellitus, Type 1

United States
University of North Carolina
National Cancer Institute (NCI)

Completed

Phase I Clinical Study of Soy Isoflavones in Healthy, Post-Menopausal Women

Drug Toxicity
UNC Lineberger Comprehensive Cancer Center
University of North Carolina, Chapel Hill; North Carolina Translational and...

Recruiting

Immuno-Oncology Database and Bioregistry (IOG)

Immune System Diseases | Autoimmune Diseases | Malignancy

United States
University of North Carolina, Chapel Hill
University of Houston; Colorado School of Public Health; University of North... and other collaborators

Enrolling by invitation

Teachers Leading the Frontlines (Tealeaf) - a Hybrid Effectiveness, Implement, and Context Trial (Tealeaf)

Child Behavior Disorders

India
University of North Carolina, Charlotte
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Technology Coaching Intervention for Black Women With Hypertension

Uncontrolled Hypertension

United States
Leanne Kaye
UNC Lineberger Comprehensive Cancer Center; University of North Carolina

Completed

Step by Step: A Tailored Walking Intervention for Breast Cancer Survivors

Breast Neoplasms | Sedentary Lifestyle | Survival Rate (Survivorship)

United States
UNC Lineberger Comprehensive Cancer Center
University of North Carolina, Chapel Hill

Completed

Olanzapine for Nausea/Vomiting Prophylaxis in Recipients of Hematopoietic Stem Cell Transplants

Chemotherapy-induced Nausea and Vomiting

United States
UNC Lineberger Comprehensive Cancer Center
University of North Carolina, Chapel Hill

Completed

Improving Survivorship Care Through Enhanced Communication and Coordination: Pilot Study

Cancer

United States
UNC Lineberger Comprehensive Cancer Center
University of North Carolina, Chapel Hill

Completed

Tacrolimus in Allogeneic Hematopoietic Stem Cell Transplant (HCT)

Acute GVHD

United States
Wake Forest University Health Sciences
University of North Carolina, Chapel Hill; North Carolina Diabetes Research...

Completed

Meals for Moms: Medically-Tailored Meals for Women Who Had Gestational Diabetes

Diabetes, Gestational | Gestational Weight Gain | Postpartum Weight Retention

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

CommunityRx-Cardiovascular Disease (CRx-CVD)

Cardiovascular Diseases | Self Efficacy

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Just-in-time Adaptive Intervention Messaging in a Digital Weight Loss Intervention for Young Adults (Nudge)

Obesity | Overweight | Overweight and Obesity

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Functional Studies of Novel Genes Mutated in Primary Ciliary Dyskinesia II: Genotype to Phenotype

Primary Ciliary Dyskinesia

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Age of Blood in Sickle Cell Transfusion

Sickle Cell Disease

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease

Kartagener Syndrome

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Screening Inhaled Allergen Challenge for Dermatophagoides Farinae (MiteScreen)

Asthma

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Withdrawn

Anakinra as a Rescue Treatment for Allergic Inflammation

Asthma, Allergic
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Evaluation of the Effect of a Nasal Allergen Challenge With Dermatophagoides Farinae Extract on Nasal Airway Inflammation in Allergic Individuals, Comparing E-cigarette Users to Cigarette Smokers and Non-smokers. (Mitey Nose)

Healthy Participants | Tobacco Smokers

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Withdrawn

Investigation of the Impact of Smoking Status on Allergen-induced Nasal Airway Inflammation Using a Cat Hair (Felis Domesticus) Extract Nasal Allergen Challenge Model (Kitty Nose)

Tobacco Smoking | Healthy Participants | E-cigarette Smokers

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Our Year of Healthy Living (Formative Research & Intervention)

Obesity

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effect of Hypertonic Saline on Mucus Clearance in Children Ages 5-12 With Cystic Fibrosis

Cystic Fibrosis

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Anticoagulation For Pulmonary Hypertension in Sickle Cell Disease

Pulmonary Hypertension

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Examining the Link Between Trace Elements and Cardiovascular Disease Risk Factors in Young Adults

Cardiovascular Diseases | Inflammation | Hypertension | Atherosclerosis | Metabolic Syndrome X

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Community Structure and Cardiovascular Mortality Trends

Myocardial Ischemia | Heart Diseases | Cardiovascular Diseases | Cerebrovascular Disorders | Cerebrovascular Accident
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Improving Care for Patients With High Blood Pressure

Hypertension | Cardiovascular Disease Risk

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effects of Sulforaphane (SFN) on Immune Response to Live Attenuated Influenza Virus in Smokers and Nonsmokers

Smoking

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effects of 2 Different Broccoli Sprout Containing Supplements on Nasal Cells in Healthy Volunteers (Broccosprout)

Healthy Adult Volunteers

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effect of a 10,000 EU Dose of Endotoxin in Allergic and Mildly Asthmatic Adults

Asthma | Rhinitis, Allergic, Perennial | Rhinitis, Allergic, Seasonal

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Sitting Interruption and Whole-body Cardiovascular Health (SWITCH)

Sedentary Behavior | Sedentary Time

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

PrecISE (Precision Interventions for Severe and/or Exacerbation-Prone Asthma) Network Study

Asthma

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Transcutaneous ARFI Ultrasound for Differentiating Carotid Plaque With High Stroke Risk

Carotid Artery Plaque | Carotid Stenosis | Plaque, Atherosclerotic

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Gene Modifiers of Cystic Fibrosis Lung Disease

Lung Diseases | Cystic Fibrosis

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Molecular Phenotypes for Cystic Fibrosis Lung Disease

Lung Diseases | Cystic Fibrosis

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Identification of Allergic Asthmatics Reactive to Felis Catus (Cat Hair) Allergen Inhalation

Asthma Atopic

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

In-vivo Effects of E-cigarette Aerosol on Innate Lung Host Defense (Cinimic)

Smoking | Healthy

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Withdrawn

Late Phase Administration Anakinra as a Rescue Treatment for Inhaled Allergen Challenge-Induced Airway Inflammation (LateAna)

Asthma
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Completed

The Effect of Rivaroxaban in Sickle Cell Disease

Sickle Cell Anemia | Sickle Cell-Beta0-Thalassemia

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effect of Atorvastatin on Endothelial Dysfunction and Albuminuria in Sickle Cell Disease (ENDO)

Sickle Cell Disease | Sickle Cell Nephropathy

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Educational Program for Various Health Literacy Levels to Improve the Health of Individuals With Heart Failure

Heart Failure, Congestive

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Completed

CVD Nutrition Modules Tailored to Low Literacy Skills

Heart Diseases | Cardiovascular Diseases
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Hepatitis Delta Infections in Hemophiliacs

Liver Diseases | Hemophilia A | Hepatitis, Viral, Human | Blood Disease
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Life Course Socioeconomic Status, Social Context and Cardiovascular Disease

Cardiovascular Diseases | Coronary Disease | Atherosclerosis
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Endotoxin and Bronchial Inflammation in Asthma

Lung Diseases | Inflammation | Asthma
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Study of Dust Mite Inhalation in Humans

Allergy | Mild Asthma

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effects of Neighborhood SES on Coronary Heart Disease Burden in Communities - Ancillary to ARIC

Heart Diseases | Cardiovascular Diseases | Coronary Disease
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Comparison of Two Workplace-Sponsored Obesity Prevention Programs

Weight Loss
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Responses to Live Attenuated Influenza Virus (LAIV) in Chronic Obstructive Pulmonary Disease (COPD)

COPD

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Phase I Assessment of Hypertonic Saline in Moderate to Severe Asthmatics

Moderate to Severe Asthma

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Dietary Effects on Lipoproteins and Thrombogenic Activity (DELTA)

Myocardial Ischemia | Heart Diseases | Cardiovascular Diseases | Coronary Disease | Thrombosis | Hyperlipoproteinemia | Coronary Heart Disease Risk Reduction

Clinical Trials Sponsored by Lung Cancer Initiative of North Carolina

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Zambia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations