Clinical Trials Sponsored by Lykos Therapeutics

Total 6278 results

Lykos Therapeutics

Not yet recruiting

A Multi-Site Study of MDMA-Assisted Psychotherapy for Eating Disorders (MED1)

Binge-Eating Disorder | Anorexia Nervosa Restricting Type
Lykos Therapeutics

Completed

A Multi-Site Open-Label Extension Study of MDMA-Assisted Psychotherapy for PTSD (MAPPUSX)

PTSD

United States, Canada, Israel
Lykos Therapeutics

Completed

MDMA-Assisted Psychotherapy in People With Posttraumatic Stress Disorder

Posttraumatic Stress Disorder

United States
Lykos Therapeutics

Completed

Study Comparing Three Doses of MDMA Along With Therapy in Veterans With Posttraumatic Stress Disorder

Posttraumatic Stress Disorder

United States
Lykos Therapeutics

Completed

Evaluation of MDMA on Startle Response

Startle Response

United States
Lykos Therapeutics

Completed

MDMA-Assisted Psychotherapy for Anxiety Associated With a Life-Threatening Illness

Anxiety

United States
Lykos Therapeutics

Withdrawn

Study of Feasibility and Safety of MDMA-Assisted Group Therapy for the Treatment of PTSD in Veterans (MPG1)

PTSD
Lykos Therapeutics

Completed

Study of Safety and Effects of MDMA-assisted Psychotherapy for Treatment of PTSD (Canada)

Posttraumatic Stress Disorder

Canada
Lykos Therapeutics

Terminated

Randomized Placebo-controlled Study of MDMA-assisted Therapy in People With PTSD - Israel

Posttraumatic Stress Disorder

Israel
Lykos Therapeutics

No longer available

A Multi-site Expanded Access Program for MDMA-assisted Psychotherapy for Patients With Treatment-resistant PTSD (EAMP1)

Post Traumatic Stress Disorder

United States
Lykos Therapeutics

Terminated

Randomized, Double-blind, Controlled of MDMA-assisted Psychotherapy in 12 Subjects With PTSD

Posttraumatic Stress Disorder

Canada
Lykos Therapeutics

Enrolling by invitation

Long-Term Safety and Effectiveness of MDMA-Assisted Therapy for PTSD (MPLONG)

PTSD

United States, Canada, Israel
Lykos Therapeutics

Active, not recruiting

Study Comparing Two Versus Three Active MDMA-assisted Sessions in U.S. Military Veterans With Chronic PTSD (MPVA6)

PTSD

United States
Lykos Therapeutics

Completed

Randomized, Double-blind, Active Placebo-Controlled Pilot Study of MDMA-assisted Psychotherapy in People With Chronic PTSD

Posttraumatic Stress Disorder (PTSD)

Israel
Lykos Therapeutics

Withdrawn

Study of Safety and Effects of MDMA-assisted Therapy for Treatment of PTSD (NUMCAP1)

Posttraumatic Stress Disorder
Lykos Therapeutics

Completed

Exploring Mechanisms of Action in MDMA-assisted Psychotherapy for PTSD

Posttraumatic Stress Disorder

United States
Lykos Therapeutics

Completed

Psychological Effects of Methylenedioxymethamphetamine (MDMA) When Administered to Healthy Volunteers (MT-1)

Psychological Effects of Study Drug

United States
Lykos Therapeutics

Not yet recruiting

Psychological Effects of Methylenedioxymethamphetamine (MDMA) When Administered to Healthy Volunteers (MT-2)

Psychological Effects of Study Drug
Lykos Therapeutics

Not yet recruiting

MDMA in Subjects With Moderate Hepatic Impairment and Subjects With Normal Hepatic Function

Pharmacokinetics | Hepatic Impairment

United States
Lykos Therapeutics

Completed

Food Effects on Bioavailability of MDMA in Healthy Volunteers (MPKF)

Pharmacokinetics

United States
Lykos Therapeutics

Completed

Open Label Multi-Site Study of Safety and Effects of MDMA-assisted Therapy for Treatment of PTSD

PTSD

United States
Lykos Therapeutics

Completed

A Multi-Site Phase 3 Study of MDMA-Assisted Psychotherapy for PTSD (MAPP2)

Posttraumatic Stress Disorder

United States, Israel
Lykos Therapeutics

Completed

A Multi-Site Phase 3 Study of MDMA-Assisted Psychotherapy for PTSD (MAPP1)

Posttraumatic Stress Disorder

United States, Israel, Canada
Lykos Therapeutics

Completed

Additional MDMA-assisted Therapy for People Who Relapsed After MDMA-assisted Therapy Trial

Posttraumatic Stress Disorder

United States
Lykos Therapeutics

Completed

Dose-Response Study of MDMA-assisted Psychotherapy in People With PTSD

Posttraumatic Stress Disorder

United States
Lykos Therapeutics

Completed

MDMA-Assisted Cognitive-Behavioral Conjoint Therapy (CBCT) in Dyads in Which 1 Member Has Chronic PTSD

Posttraumatic Stress Disorder

United States
Lykos Therapeutics

Completed

Correlates of Anxiety Associated With a Life-threatening Illness

Anxiety

United States
Lykos Therapeutics
Swiss Medical Association for Psycholytic Therapy

Completed

Study of 3,4-Methylenedioxymethamphetamine-assisted Psychotherapy in People With Posttraumatic Stress Disorder

Posttraumatic Stress Disorder

Switzerland
LeKos LLP

Recruiting

EVALUATION OF THE EFFECTIVENESS AND SAFETY OF DOSPRAY® NAZAL SPRAY IN THE SYMPTOMATIC TREATMENT OF PERSISTENT ALLERGIC RHINITIS: A POST-REGISTRATION OBSERVATION STUDY

Allergic Rhinitis

Kazakhstan
Dr. Leslie Morland
San Diego Veterans Healthcare System; Healing Breakthrough; Lykos Therapeutics

Recruiting

MDMA-assisted Brief Cognitive Behavioral Conjoint Therapy for PTSD (MDMA-bCBCT)

PTSD | Relational Problems

United States
Lykos Therapeutics
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center

Completed

Phase 2 Pilot Safety Study of MDMA-assisted Therapy for Social Anxiety in Autistic Adults

Social Anxiety in Autistic Adults

United States
Ranok Therapeutics (Hangzhou) Co., Ltd.

Recruiting

A Study of RNK05047 in Subjects With Advanced Solid Tumors/Diffuse Large B-cell Lymphoma (CHAMP-1)

Advanced Solid Tumor | DLBCL

United States
Akebia Therapeutics
Cyclerion Therapeutics

Completed

A Study to Evaluate the Soluble Guanylate Cyclase (sGC) Stimulator IW-1973 in Diabetic Nephropathy / Diabetic Kidney Disease as Measured by Albuminuria

Type 2 Diabetes Mellitus With Diabetic Nephropathy

United States
Akebia Therapeutics
Cyclerion Therapeutics

Completed

A Study of the Effect of IW-1973 on the Exercise Capacity of Patients With Heart Failure With Preserved Ejection Fraction (HFpEF) (CAPACITY-HFpEF)

Heart Failure With Preserved Ejection Fraction

United States, Canada
CRISPR Therapeutics AG

Recruiting

A Safety and Efficacy Study Evaluating CTX131 in Adult Subjects With Relapsed or Refractory Solid Tumors

Clear Cell Renal Cell Carcinoma | Pancreatic Adenocarcinoma | Cervical Carcinoma | Malignant Pleural Mesothelioma | Esophageal Carcinoma

United States
CRISPR Therapeutics AG

Active, not recruiting

A Safety and Efficacy Study Evaluating CTX130 in Subjects With Relapsed or Refractory T or B Cell Malignancies (COBALT-LYM)

T Cell Lymphoma

United States, Australia, Canada
CRISPR Therapeutics AG

Active, not recruiting

A Safety and Efficacy Study Evaluating CTX110 in Subjects With Relapsed or Refractory B-Cell Malignancies (CARBON)

B-cell Lymphoma | Non-Hodgkin Lymphoma | B-cell Malignancy | Adult B Cell ALL

United States, Spain, Canada, France, Germany, Australia
Bacainn Therapeutics, Inc.

Completed

A Phase 1, Single-Ascending-Dose Study of BT051 in Healthy Subjects

Healthy Volunteers

United States
Celsus Therapeutics PLC

Terminated

Double-Blind, Trial to Evaluate the Safety and Efficacy of MRX-6 Cream 2% (C012013)

Atopic Dermatitis

Israel
Eikon Therapeutics
Impact Therapeutics, Inc.

Recruiting

A First-in-human Study of PARP1 Selective Inhibitor, IMP1734, in Participants With Advanced Solid Tumors

Advanced Solid Tumor

Australia, United States
CRISPR Therapeutics AG

Active, not recruiting

A Safety and Efficacy Study Evaluating CTX130 in Subjects With Relapsed or Refractory Renal Cell Carcinoma (COBALT-RCC)

Renal Cell Carcinoma

United States, Australia, Canada, Netherlands
APRINOIA Therapeutics, LLC

Active, not recruiting

A First-in-Human Study to Assess Single Doses of APNmAb005 in Healthy Participants

Alzheimer Disease | Tauopathies | Healthy Volunteers

United States
CRISPR Therapeutics AG

Recruiting

A Safety and Efficacy Study Evaluating CTX112 in Subjects With Relapsed or Refractory B-Cell Malignancies

Follicular Lymphoma | B-cell Lymphoma | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Non-Hodgkin Lymphoma | B-cell Malignancy | Large B-cell Lymphoma | Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

United States
CRISPR Therapeutics AG

Enrolling by invitation

A Long-term Follow-up Study of Subjects Who Received CRISPR CAR T Cellular Therapies

Hematologic Malignancy | Solid Malignancy

United States
CRISPR Therapeutics AG

Active, not recruiting

A Safety and Efficacy Study Evaluating CTX120 in Subjects With Relapsed or Refractory Multiple Myeloma

Multiple Myeloma

United States, Spain, Australia, Canada
APRINOIA Therapeutics, LLC

Active, not recruiting

Evaluation of [18F]APN-1607 PET Uptake in Alzheimer's Disease Patients Compared With Healthy Subjects

Healthy Volunteers | Alzheimer's Disease | Mild Cognitive Impairment Due to Alzheimer's Disease

United States
CRISPR Therapeutics AG
ViaCyte

Recruiting

An Open-Label, FIH Study Evaluating the Safety, Tolerability, and Efficacy of VCTX211 Combination Product in Subjects With T1D

Glucose Metabolism Disorders | Immune System Diseases | Autoimmune Diseases | Diabetes Mellitus | Endocrine System Diseases | Diabetes Mellitus, Type 1 | Metabolic Disease

Canada
iCell Gene Therapeutics
iCar Bio Therapeutics

Not yet recruiting

Anti-CD33 CAR-T Cells for the Treatment of Relapsed/Refractory CD33+ Acute Myeloid Leukemia

High Risk Hematologic Malignancies | Relapsed and/or Refractory Acute Myeloid Leukemia

China
Melinta Therapeutics, LLC

Recruiting

Open-Label, Dose-Finding, Pharmacokinetics, Safety and Tolerability Study of Oritavancin in Pediatric Patients With Suspected or Confirmed Bacterial Infections

Gram Positive Bacterial Infections

United States
TenNor Therapeutics Limited

Completed

TNP-2092 to Treat Acute Bacterial Skin and Skin Structure Infection (P2_ABSSSI)

Gram-Positive Bacterial Infections | Skin and Subcutaneous Tissue Bacterial Infections

United States

Clinical Trials Sponsored by Lykos Therapeutics

Sponsors and Collaborators

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CROs in Bahrain

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