Clinical Trials Sponsored by MERCK SHARP & DOHME DE ESPAÑA S.A.

Total 71 results

Maimónides Biomedical Research Institute of Córdoba
MERCK SHARP & DOHME DE ESPAÑA S.A.

Not yet recruiting

Efficacy of Letermovir in Preventing Cytomegalovirus (CMV) Infection in Lung Transplant Recipients vs. Valganciclovir. (LETERCOR)

Infections, Cytomegalovirus

Spain
Grupo Espanol Multidisciplinario del Cancer Digestivo
Merk Sharp & Dohme España S.A.

Recruiting

Pembrolizumab and Olaparib in Homologous-recombination Deficient (HRD) Advanced Colorectal Cancer (CRC). (PEMBROLA)

Metastatic Colorectal Cancer

Spain
Grupo Español de Tratamiento de Tumores de Cabeza...
Merck Sharp & Dohme LLC; Pivotal S.L.

Terminated

Paclitaxel vs Paclitaxel + Cetuximab in Recurrent - Metastatic Head & Neck Carcinoma After Failure of a 1º Chemotherapy (EXTAX)

Head and Neck Cancer
Sociedad Española de Neumología y Cirugía Torácica
Merck Sharp & Dohme LLC

Completed

Impact of Adherence to Treatment in Asthma Control

Asthma

Spain
Faes Farma, S.A.
Merck Sharp & Dohme LLC; Allied Research International

Completed

Efficacy, Safety and PK of Once or Twice Daily Bilastine (10 or 20 mg) Compared With Placebo in the Symptomatic Treatment of SAR

Hypersensitivity | Allergic Conjunctivitis | Seasonal Allergic Rhinitis | Hay Fever

United States
Celyad Oncology SA
Merck Sharp & Dohme LLC

Recruiting

Study of Pembrolizumab Treatment After CYAD-101 With FOLFOX Preconditioning in Metastatic Colorectal Cancer

Unresectable Metastatic Colorectal Cancer

Belgium, United States
Fundación de investigación HM
Merck Sharp & Dohme LLC

Unknown

Cytomegalovirus Infection in Critically Ill Patients and Patients Receiving Anticancer Therapy (CMV-ICU)

CMV
Istituti Clinici Scientifici Maugeri SpA
Merck Sharp & Dohme LLC

Recruiting

Pembrolizumab in High-risk Thyroid Cancer (NePenThe)

Differentiated Thyroid Cancer

Italy
Institut Cancerologie de l'Ouest
Merck Sharp & Dohme LLC

Terminated

Trial Testing Ftorafur (UFT) Associated With Neoadjuvant Radiotherapy Versus Radiotherapy Alone in Rectal Adenocarcinoma (UFT RT Phase 3)

Rectal Cancer | Stage II/III | T3 or T4 (Only Anal Extension) Rectal Cancer | N0-2 | M0

France
Istituti Clinici Scientifici Maugeri SpA
Merck Sharp & Dohme LLC

Not yet recruiting

Pembrolizumab in Locally Advanced Sinonasal Carcinoma (NeoPeSino)

Sinonasal Undifferentiated Carcinoma

Italy
Instituto Valenciano de Infertilidade de Lisboa
Merck Sharp & Dohme LLC

Completed

Effect of Different Ovarian Stimulation Protocols on Endometrial Receptivity

Infertility, Female | Endometrial Diseases

Portugal
Centre de Recherche Médicale de Lambaréné
Merck Sharp & Dohme LLC

Completed

Safety and Immunogenicity of the rVSVΔG-ZEBOV-GP Ebola Virus Vaccine Candidate in Children Living in Lambaréné, Gabon (EBOLAPED)

Ebola Virus Disease

Gabon
Beneficência Portuguesa de São Paulo
Merck Sharp & Dohme LLC

Not yet recruiting

Ceftolozane/Tazobactam Versus Meropenem for Febrile Neutropenia on Patients Colonized With or at Risk for Infection With Extended Spectrum Beta Lactamase - Producing Pathogens (CLEMENT)

Febrile Neutropenia

Brazil
CHU de Quebec-Universite Laval
Merck Sharp & Dohme LLC

Recruiting

Biomarkers for Neoadjuvant Pembrolizumab in Non-Metastatic Prostate Cancer Positive by 18FDG-PET Scanning (PICT-01)

Prostate Cancer

Canada
Assistance Publique - Hôpitaux de Paris
Merck Sharp & Dohme LLC

Completed

Prevalence of Chronic Thromboembolic Pulmonary Hypertension After Acute Pulmonary Embolism : (Preva-CTEPH) (Preva-CTEPH)

Pulmonary Embolism | Chronic Thromboembolic Pulmonary Hypertension (CTEPH)

France
Assistance Publique - Hôpitaux de Paris
Merck Sharp & Dohme LLC

Completed

Assessment of Prostatic Tissue Concentration of Ertapenem After a Pre-operative Administration (ERTAPRO)

Benign Prostatic Hyperplasia (BPH) Requiring Surgical Resection

France
Grupo de Estudio de Infecciones en Transplantados
Merck Sharp & Dohme LLC

Unknown

Prophylaxis With Caspofungin in High-Risk Liver Transplantation

Liver Transplantation | Fungal Infection

Spain
Cliniques universitaires Saint-Luc- Université...
Merck Sharp & Dohme LLC; Merck Serono International SA

Completed

Neoadjuvant Cetuximab in HNSCC Combined With Curative Surgery (CHIRON)

Head and Neck Cancer

Belgium
Centre Leon Berard
Merck Sharp & Dohme LLC; Debiopharm International SA

Completed

Pembrolizumab In Combination With Debio 1143 In Pancreatic and Colorectal Advanced/Metastatic Adenocarcinoma (CATRIPCA)

Adenocarcinoma of the Pancreas | Adenocarcinoma of the Rectum | Adenocarcinoma of the Colon

France
Hopital du Sacre-Coeur de Montreal
Merck Sharp & Dohme LLC

Completed

Neuromuscular Blockade: Outcome and Recovery for Laparoscopic Bariatric Surgery

Bariatric Surgery Candidate
Institut de Recherches Internationales Servier
Merck Sharp & Dohme LLC

Recruiting

Study of Vorasidenib and Pembrolizumab Combination in Recurrent or Progressive Enhancing IDH-1 Mutant Glioma

Astrocytoma

United States
Centre Hospitalier Universitaire de Saint Etienne
Merck Sharp & Dohme LLC

Completed

Golimumab in Ulcerative Colitis (UC) Patients With Loss of Response (LOR) Followed by Dose Optimization (GOLILOR)

Ulcerative Colitis

France
Centre Hospitalier Universitaire de Saint Etienne
Merck Sharp & Dohme LLC

Completed

Evaluation of the Pharmacokinetics of Caspofungin in ICU Patients (CaspoKin)

Shock

France
Instituto de Medicina Molecular João Lobo Antunes
Merck Sharp & Dohme LLC

Completed

Differences in Bone Cell Activity Between Rheumatoid Arthritis and Ankylosing Spondylitis

Rheumatoid Arthritis | Bone Resorption | Ankylosing Spondylitis

Portugal
Instituto de Medicina Molecular João Lobo Antunes
Merck Sharp & Dohme LLC

Completed

Efficacy of Golimumab in Combination With Methotrexate (MTX) Versus MTX Monotherapy, in Improving Dactylitis, in MTX naïve Psoriatic Arthritis Patients (GO-DACT)

Psoriatic Arthritis

Portugal
University Hospital, Lille
Merck Sharp & Dohme LLC; Fédération Française de Cardiologie

Recruiting

Impact of Peripheral Vascular Stiffness Assessment on Risk Prediction in Patients With Myocardial Infarction (RIGID-MI)

Myocardial Infarction | Heart Failure | Vascular Stiffness

France
Assistance Publique - Hôpitaux de Paris
Merck Sharp & Dohme LLC; Pfizer; AstraZeneca

Completed

Treat Stroke to Target (TST)

Ischemic Stroke | Transient Ischemic Attack | Atherosclerotic Stenosis

France
Objectif Recherche Vaccins SIDA
Merck Sharp & Dohme LLC; Pfizer; Cytheris SA

Completed

Therapeutic Intensification Plus Immunomodulation in HIV-infected Patients (ERAMUNE-01)

HIV-1 Infection

United Kingdom, France, Italy, Spain
Universidad Nacional Autonoma de Mexico
Merck Sharp & Dohme LLC; Secretaria de Salud, Mexico

Unknown

Two-dose Schedule of Quadrivalent HPV Recombinant Vaccine in 11-year-old Boys in Mexico City

Human Papilloma Virus

Mexico
Federation Francophone de Cancerologie Digestive
Merck Sharp & Dohme LLC; Pierre Fabre Laboratories

Recruiting

Encorafenib Plus Cetuximab in a Neoadjuvant Setting in Patients With BRAF Mutation Localised Colon or Upper Rectum Cancer (NEORAF)

Colorectal Cancer | BRAF V600E Mutation Positive

France
Núcleo de Estudos em Esportes e Ortopedia, Brazil
Merck Sharp & Dohme LLC

Unknown

Efficacy and Safety of Etoricoxib in Acute Ankle Sprain: A Double-Blind Comparative Study Among 2 Treatments Protocols

Sprains and Strains | Contusions

Brazil
Centre de Recherche en Nutrition Humaine Rhone-Alpe
Merck Sharp & Dohme LLC

Completed

Effect of Metformin on Lactate Metabolism

Hyperlactatemia

France
Hospital Universitario 12 de Octubre
Merck Sharp & Dohme LLC

Completed

Vytorin on Carotid Intima-media Thickness and Overall Rigidity (VYCTOR)

Cardiovascular Diseases
Daniel A. Siniawski
Merck Sharp & Dohme LLC

Terminated

Lipid Efficacy of the Extended Release Niacin/Laropiprant Combination in Patients With Cardiovascular Disease

Coronary Artery Disease | Dyslipidemias

Argentina
Asociacion para el Estudio de las Enfermedades...
Merck Sharp & Dohme LLC

Completed

Bitherapy With the Combination of Raltegravir and Darunavir (BIRDi) (BIRDi)

HIV/AIDS | Comorbidities

Spain
Cliniques universitaires Saint-Luc- Université...
Merck Sharp & Dohme LLC

Completed

Gemcitabine and Cetuximab in Patients With Advanced or Metastatic Biliary Tract Cancer: A Multicenter Phase II Study (ECHO)

Time to Progression

Belgium
Institut National de la Santé Et de la Recherche...
Merck Sharp & Dohme LLC

Completed

Microbiota and Bone Fragility:Study of the Relation Between Gut Microbiota and Bone Microarchitecture (MICROBONE)

Bone Loss, Age-related

France
Luis Jara-Palomares, MD
Merck Sharp & Dohme LLC; Sociedad Española de Neumología y Cirugía Torácica

Completed

Symptom-related Screening for Early Detection of CTEPH.

Pulmonary Embolism | Dyspnea | Symptoms and Signs | CTEPH

Spain
Instituto Nacional de Ciencias Medicas y Nutricion...
Merck Sharp & Dohme LLC

Completed

Treatment With Sitagliptin for Reactive Hypoglycemia Secondary to Dysinsulinism

Reactive Hypoglycemia

Mexico
Instituto Nacional de Ciencias Medicas y Nutricion...
Merck Sharp & Dohme LLC

Withdrawn

Efficacy of Ezetimibe/Simvastatin 10/20 mg and MK0524A (1-2 g/Day) in Mixed Hyperlipidemia and Two or More Risk Factors

Cardiovascular Diseases | Hyperlipidemia
Fundació Institut de Recerca de l'Hospital de la...
Merck Sharp & Dohme LLC

Unknown

Identifying Improvements in an ED Elder Friendly Area Based on Patient Experience (EDEFA_TheirVoice Project) (TheirVoice)

Emergencies | Aging

Spain
Hospital Universitario de Cabuenes
Merck Sharp & Dohme LLC; Hospital Universitario Central de Asturias; Instituto...

Unknown

PROSPECTIVE STUDY OF PREDISPOSING FACTORS OF REFRACTARY Clostridium Difficile INFECTION. INFLUENCE OF THE GUT MICROBIOMA

Clostridium Difficile Infection
Servier Bio-Innovation LLC
Merck Sharp & Dohme LLC; Institut de Recherches Internationales Servier

Not yet recruiting

A Study to Evaluate the Safety and the Activity of S095029 as Part of Combination Therapy in Advanced Gastroesophageal Junction/Gastric Cancers.

MSI-H/dMMR Gastroesophageal-junction Cancer | MSI-H/dMMR Gastric Cancer
Institut de Médecine et d'Epidémiologie Appliquée...
Merck Sharp & Dohme LLC

Active, not recruiting

"Observational Study on Tolerability and Observance of Post-exposure Prophylaxis With Doravirine in HIV Viral Risk" (DORASPEP)

HIV Infections

France
Centre Hospitalier Intercommunal de Toulon La Seyne...
Merck Sharp & Dohme LLC; Abbott

Completed

IntensVIH: Impact Of Therapy Intensification By An Integrase Inhibitor +/- CCR5 Inhibitor On The Lymphoid Reservoir For Hiv-1 In Chronically Infected Patients (IntensVIH)

HIV Infections

France
Association Clinique Thérapeutique Infantile du...
Sanofi; GlaxoSmithKline; Merck Sharp & Dohme LLC

Recruiting

Pediatric Pertussis in Ambulatory Settings (ACTIVCOQ)

Children, Only | Ambulatory | Pertussis/Whooping Cough

France
José María Aguado García, MD, PhD
Merck Sharp & Dohme LLC; Hospital Universitario 12 de Octubre

Completed

Antimicrobial Stewardship Program for Clostridium Difficile Infection. (PACTA-ICD)

Enterocolitis, Pseudomembranous | Clostridium Difficile

Spain
Carlos III Health Institute
Merck Sharp & Dohme LLC; Red Temática de Investigación Cooperativa en Sida

Unknown

Pregnancy in Women With HIV Infection

HIV Infections | Pregnancy Related
Preventive Oncology International, Inc.
Merck Sharp & Dohme LLC; Peru Instituto Nacional de Enfermadades Neoplasticas...

Completed

The Development of a "Mother/Child, Screen, Treat and Vaccinate Program" in Manchay and Iquitos, Peru (PERCAPS)

Cervical Cancer | Cervical Intraepithelial Neoplasia | Human Papillomavirus | Cervical Dysplasia | Cervical Neoplasm

Peru
Fundación Pública Andaluza para la Investigación...
Merck Sharp & Dohme LLC

Completed

Cytomegalovirus Infection After HSCT and PT-CY as GVHD Prophylaxis >> GVHD PROPHYLAXIS ERA (CY-CMV-2020)

CMV Infection

Spain

Clinical Trials Sponsored by MERCK SHARP & DOHME DE ESPAÑA S.A.

Sponsors and Collaborators

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