Clinical Trials Sponsored by Mallinckrodt, Inc.

Total 35846 results

Mallinckrodt
Mallinckrodt ARD Inc.

Completed

Observational Registry of Acthar Gel for Participants With Multiple Sclerosis Relapse

Multiple Sclerosis, Relapsing-Remitting

United States
Therakos, Inc., a Mallinckrodt Company

Terminated

Methoxsalen and Extracorporeal Photopheresis (ECP) for the Treatment of Pediatric Participants With Steroid Refractory Acute Graft Versus Host Disease

Steroid Refractory Acute Graft Versus Host Disease

United States, Spain, France, Austria, Germany, Hungary, Italy, United Kingdom
NephroNet, Inc.
Mallinckrodt

Active, not recruiting

A Study of Acthar Gel Alone or With Tacrolimus to Reduce Proteinuria in Fibrillary Glomerulopathy Patients (FACT)

Fibrillary Glomerulonephritis

United States
NephroNet, Inc.
Mallinckrodt

Withdrawn

Comparative and Efficacy Study of ACTHar Gel Alone or in Combination With Tacrolimus in Fibrillary Glomerulopathy (FACT)

Renal Disease

United States
Ocera Therapeutics, Inc.

Completed

Phase 2B Efficacy/Safety of Ornithine Phenylacetate in Hospitalized Cirrhotic Patients With Hepatic Encephalopathy (STOP-HE) (STOP-HE)

Hepatic Encephalopathy | Acute Episode of Overt Hepatic Encephalopathy

Belgium, Germany, Italy, Spain, United States, France, Austria, Russian Federation, Czechia, Australia, Hungary, Israel, Netherlands, Bulgaria, Estonia, Denmark, New Zealand
Columbia University
Mallinckrodt, Inc.

Recruiting

Photopheresis in Early-stage Mycosis Fungoides

Mycosis Fungoides | Cutaneous T Cell Lymphoma

United States
Ocera Therapeutics, Inc.

Completed

OCR002-SP103 - Oral Immediate Release Study

Cirrhosis

United States
Neurologique Foundation, Inc.
Mallinckrodt

Terminated

Efficacy Study of Adrenocorticotropin Hormone to Treat Multiple Sclerosis (MS) Relapses After Sub-responding to an Initial 3 Day Course of Intravenous (IV) Methylprednisolone (RECLAIM)

Multiple Sclerosis

United States
Ocera Therapeutics, Inc.

No longer available

Emergency Use of OCR-002 in Acute Liver Failure (ALF)

Acute Liver Failure

United States
Mallinckrodt
Nuvo Research Inc.

Approved for marketing

Compassionate Use of Pennsaid Topical Lotion (Diclofenac) in Osteo or Rheumatoid Arthritis

Osteoarthritis of the Hand
Mallinckrodt ARD LLC

Terminated

A Study to Assess the Efficacy and Safety of MNK-1411 in Duchenne Muscular Dystrophy (BRAVE)

Muscular Dystrophy, Duchenne

Spain, Bulgaria, Italy, United States, Mexico, Israel, Serbia, Turkey
Mallinckrodt

Completed

Acthar Gel in Participants With Pulmonary Sarcoidosis (PULSAR)

Sarcoidosis, Pulmonary

United States
Mallinckrodt

Completed

MNK6106 for Liver Disease (Hepatic Cirrhosis) That in the Past Has Affected the Brain (Hepatic Encephalopathy)

Hepatic Cirrhosis | Hepatic Encephalopathy (HE)

United States, Puerto Rico
Mallinckrodt

Completed

Study to Test the Effectiveness of Controlled-Release OROS® Hydromorphone HCl Compared to Placebo in Patients With Chronic Low Back Pain

Chronic Low Back Pain
Mallinckrodt

Withdrawn

Safety and Efficacy Study of Acthar in Subjects With ARDS

Acute Respiratory Distress Syndrome
Mallinckrodt

Completed

U.S. Study of Fibrocaps in Surgical Hemostasis

Postoperative Hemorrhage

United States
Mallinckrodt

Completed

Safety and Efficacy Study of Photopheresis With UVADEX to Prevent Graft-versus-Host Disease

Graft-versus-Host Disease

United States, Australia, United Kingdom, Slovakia, Brazil, Germany, Italy, Portugal, Turkey
Mallinckrodt

Withdrawn

IK-1001 (Sodium Sulfide (Na2S) for Injection) in Subjects With Acute ST-Segment Elevation Myocardial Infarction

ST-Segment Elevation Myocardial Infraction
Mallinckrodt

Completed

Study of the Safety & Efficacy of Intravenous Acetaminophen in Pediatric Inpatients

Pain | Fever

United States
Mallinckrodt

Completed

Single-Dose PK Study of an Oxycodone/Acetaminophen Solution in Healthy Subjects

Healthy Volunteers

United States
Mallinckrodt

Terminated

Trial to Study the Safety of Intravenous MNK-010 in Advanced Solid Tumors

Advanced Solid Tumors

United States
Mallinckrodt

Completed

Safety and Efficacy of COV795 in Moderate to Severe Post-Operative Bunionectomy Pain With an Open-label Extension

Pain, Postoperative | Bunion

United States
Mallinckrodt

Completed

Efficacy and Safety of Intravenous Acetaminophen Over 48 Hrs for the Treatment of Post-op Pain After Gynecologic Surgery

Postoperative Pain | Hysterectomy

United States
Mallinckrodt

Withdrawn

Safety and Tolerability Study of Inhaled Carbon Monoxide in Kidney Transplant Patients

Kidney Transplantation

United States
Mallinckrodt

Terminated

Reduction of Ischemia-Reperfusion Mediated Cardiac Injury in Subjects Undergoing Coronary Artery Bypass Graft Surgery

Coronary Artery Bypass Surgery

Canada, Australia
Mallinckrodt

Terminated

Inhaled Nitric Oxide in Neonates With Elevated A-a DO2 Gradients Not Requiring Mechanical Ventilation

Lung Disease | Hypoxemia | Respiratory Acidosis

United States
Mallinckrodt

Completed

Assessing Relapse in Multiple Sclerosis (ARMS) Questionnaire (ARMS)

Multiple Sclerosis

United States
Mallinckrodt

Completed

Fasting Study of Controlled-Release Oxycodone Hydrochloride 40 mg Tablets and OxyContin® 40 mg Tablets

Healthy

United States
Mallinckrodt

Terminated

Study to Evaluate the Effect of Age (Geriatric) and Kidney Function on the Safety, Efficacy and Pharmacokinetics of OctreoScan in Patients Who Have New or Recurrent Tumors

Solid Tumors

United States
Mallinckrodt

Completed

A Study of Fibrocaps in Liver Surgery in the Netherlands

Postoperative Hemorrhage

Netherlands
Mallinckrodt

Terminated

Effects of Inhaled Nitric Oxide in the Treatment of Acute Hypoxemic Respiratory Failure (AHRF) in Pediatrics

Respiratory Insufficiency | Anoxemia

United States
Mallinckrodt

Completed

Study To Confirm Efficacy and Safety of Terlipressin in Hepatorenal Syndrome (HRS) Type 1

Hepatorenal Syndrome

United States, Canada
Mallinckrodt

Withdrawn

MNK-6105 for Patients With Cirrhosis and High Ammonia Levels Affecting Brain Function

Hepatic Encephalopathy
Mallinckrodt

Completed

Impact of Acthar on Everyday Life of Participants With Severe Keratitis

Keratitis

United States
Mallinckrodt

Completed

Study of COV795 in Subjects With Osteoarthritis or Chronic Low Back Pain

Osteoarthritis | Low Back Pain

United States
Mallinckrodt

Completed

Acthar Gel for Active Systemic Lupus Erythematosus (SLE)

Lupus Erythematosus, Systemic

United States, Argentina, Mexico, Chile, Peru
Mallinckrodt

Terminated

Topical Raplixa for Surgical Bleeding in Children

Surgical Bleeding

United States
Mallinckrodt

Terminated

Pharmacokinetics (PK) and Safety Study of XARTEMIS® XR in Postsurgical Adolescent Subjects With Moderate to Severe Acute Pain

Acute Pain

United States
Mallinckrodt

Completed

A Study of Fibrocaps™ in Surgical Bleeding (FINISH-3)

Mild or Moderate Surgical Bleeding

United States, Netherlands, United Kingdom, Belgium
Mallinckrodt

Completed

Inhaled Nitric Oxide (INO) for the Prevention of Bronchopulmonary Dysplasia (BPD) in Preterm Infants

Bronchopulmonary Dysplasia

United States, Canada
Mallinckrodt

Completed

A Safety and Efficacy Study Comparing Fibrocaps and Tachosil in Hepatic Surgery

Surgical Bleeding

Germany, Austria
Mallinckrodt

Completed

Safety and Efficacy Study of Photopheresis Plus Standard Therapy to Treat Chronic Graft-versus-Host Disease

Graft-versus-Host Disease

United States, Australia, France, Italy, Austria, Germany, Portugal, Slovakia, Spain, Switzerland, Turkey, United Kingdom
Mallinckrodt

Completed

A Study to Explore the Safety and Tolerability of Acthar in Patients With Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis

United States
Mallinckrodt

Completed

Safety and Pharmacokinetic (PK) Study of Intravenous (IV) Acetaminophen Administration in Pediatric Inpatients

Pain | Fever

United States
Mallinckrodt

Completed

Safety and Efficacy of Intravenous Acetaminophen (IV APAP) in Adult Inpatients

Fever | Acute Pain

United States
Mallinckrodt

Completed

Fasting Study of Hydromorphone Hydrochloride 8 mg Tablets and Dilaudid 8 mg Tablets

Healthy

United States
Mallinckrodt

Completed

Open Label Safety and Tolerability Study of COV155 in Subjects With Osteoarthritis (OA) or Chronic Low Back Pain (CLBP)

Osteoarthritis, Knee | Chronic Low Back Pain | Osteoarthritis, Hip

United States
Mallinckrodt

Completed

Fed Study of Chlorpheniramine Polistirex and Hydrocodone Polistirex Capsules and Tussionex® Pennkinetic® Extended Release Oral Suspension

Healthy

United States
Mallinckrodt

Completed

Fasting Study of Oxycodone Hydrochloride 30 mg Tablets and Roxicodone™ 30 mg Tablets

Healthy

United States
Mallinckrodt

Completed

Fed Study of Oxycodone Hydrochloride 30 mg Tablets and Roxicodone™ 30 mg Tablets

Healthy

United States

3

Subscribe