Clinical Trials Sponsored by Marinus Pharmaceuticals

Total 19926 results

Marinus Pharmaceuticals

Not yet recruiting

Double-blind, Randomized, Placebo-controlled Trial of Ganaxolone in CDKL5 Deficiency Patients 6 Months to Less Than 2 Years Old

CDKL5 Deficiency Disorder
Marinus Pharmaceuticals

Active, not recruiting

Adjunctive GNX Treatment Compared With Placebo in Children and Adults With TSC-related Epilepsy (TrustTSC)

Tuberous Sclerosis Complex

United States, Spain, United Kingdom, Israel, Italy, Germany, France, Canada
Marinus Pharmaceuticals

Terminated

A Two-year Open-label Extension Study of Ganaxolone in Patients With Drug-resistant Partial-onset Seizures

Drug Resistant Partial Onset Seizure

United States
Marinus Pharmaceuticals

Terminated

Open-label Extension to Protocol 1042-0500

Infantile Spasms

United States
Marinus Pharmaceuticals

Completed

Study of Adjunctive Ganaxolone Treatment in Children and Young Adults With CDKL5 Deficiency Disorder (Marigold)

CDKL5 Deficiency Disorder

United States, Australia, France, Israel, Italy, Poland, Russian Federation, United Kingdom
Marinus Pharmaceuticals

Completed

Open-Label PoC Trial of Ganaxolone in Children With PCDH19 Female Pediatric Epilepsy and Other Rare Genetic Epilepsies

Epilepsy

United States, Italy
Marinus Pharmaceuticals

Completed

A Randomized, Controlled Trial of Ganaxolone in Adult Uncontrolled Partial-Onset Seizures

Partial Epilepsy | Catamenial Epilepsy

United States
Marinus Pharmaceuticals

Completed

Phase 3 Study of Adjunctive Ganaxolone in Adults With Drug-resistant Partial Onset Seizures and Open-label Extension

Drug Resistant Partial Onset Seizure

United States, Australia, Russian Federation, Bulgaria, Germany, Poland
Marinus Pharmaceuticals

Completed

Open-label Extension to Protocol 1042-0600

Epilepsies, Partial

United States
Marinus Pharmaceuticals

Active, not recruiting

Randomized Therapy In Status Epilepticus (RAISE)

Status Epilepticus

United States, Australia, Canada
Marinus Pharmaceuticals

Enrolling by invitation

Open-label Study of Adjunctive GNX Treatment in Children and Adults With TSC-related Epilepsy

Tuberous Sclerosis Complex

United States, Spain, United Kingdom, China, Italy, France, Israel, Germany, Canada, Australia
Marinus Pharmaceuticals

Completed

A Clinical Trial of Oral Ganaxolone in Women With Postpartum Depression

Behavioral Symptoms | Depressive Disorder | Depression | Mood Disorders | Pregnancy Complications | Depression, Postpartum | Mental Disorder | Postpartum Disorder | PPD | Postpartum Blues

United States
Marinus Pharmaceuticals

Completed

A Randomized, Controlled Trial of Ganaxolone in Patients With Infantile Spasms

Infantile Spasms

United States
Marinus Pharmaceuticals

Completed

Adjunctive Ganaxolone Treatment (Part A) in TSC Followed by Long-term Treatment (Part B) (TSC)

Tuberous Sclerosis

United States
Marinus Pharmaceuticals

Completed

A Treatment Use Protocol for Subjects Continuing on From the Open-label Extension 0601 (0602)

Epilepsy, Complex Partial

United States
Marinus Pharmaceuticals

Withdrawn

To Evaluate the Efficacy, Safety, and Tolerability of Intravenous Ganaxolone Added to Standard of Care in Refractory Status Epilepticus (RSE)

Refractory Status Epilepticus

Spain, Switzerland, Germany, France, Austria, Italy, Belgium, United Kingdom, Czechia, Croatia, Finland, Lithuania, Israel, Hungary, Poland, Slovakia
Marinus Pharmaceuticals

Withdrawn

Safety and Efficacy Study of IV Ganaxolone as Adjuvant Therapy for Established Status Epilepticus (ESE)

Status Epilepticus

United States
Marinus Pharmaceuticals

No longer available

Ganaxolone Expanded Access Program Compassionate Use (CDD)

CDKL5 Disorder
Marinus Pharmaceuticals

Completed

A Clinical Trial of Intravenous (IV) Ganaxolone in Women With Postpartum Depression

Behavioral Symptoms | Mental Disorders | Depressive Disorder | Depression | Mood Disorders | Pregnancy Complications | Depression, Postpartum | Puerperal Disorders | Postpartum | PPD

United States
Marinus Pharmaceuticals

Completed

Study of Adjunctive Ganaxolone Treatment in Female Children With Protocadherin 19 (PCDH19)-Related Epilepsy (Violet Study)

PCDH19-Related Epilepsy

United States, Hungary, Italy, Netherlands, Poland
Marinus Pharmaceuticals

Completed

Intravenous Ganaxolone as Adjunctive Therapy to Treat Subjects With Status Epilepticus

Epilepsy | Status Epilepticus | Convulsive Status EPILEPTICUS | Non Convulsive Status Epilepticus

United States
Marius Pharmaceuticals
Syneos Health

Completed

Ambulatory Blood Pressure Monitoring (ABPM) Extension Study of Oral Testosterone Undecanoate in Hypogonadal Men

Hypogonadism, Male

United States
Marius Pharmaceuticals
Syneos Health

Completed

Efficacy and Safety of Oral Testosterone Undecanoate in Hypogonadal Men

Hypogonadism, Male

United States
Marinus Pharmaceuticals
University of California, Davis; U.S. Army Medical Research and Development...

Completed

Ganaxolone Treatment in Children With Fragile X Syndrome

Fragile x Syndrome

Belgium, United States
Magnus Medical

Recruiting

Open Label Optimization Study (OLO)

Major Depressive Disorder

United States
Marcus Migura
Mercy Health

Completed

A Transparent Elasticized Adhesive Occlusive Compression Bandage for Use as an Arterial Tourniquet

Hemorrhage | Vascular Injury

United States
Marius Henriksen

Recruiting

Metformin Treatment of Patients With Hand Osteoarthritis (METRO)

Hand Osteoarthritis

Denmark
Marius Henriksen

Active, not recruiting

Intensive Diet vs Knee Arthroplasty for Knee Osteoarthritis (INKA)

Knee Osteoarthritis

Denmark
Marius Henriksen

Completed

Technology Assisted Physical Activity Among Hospitalised Medical Patients (TAPAS-2)

Pulmonary Disease | Cardiac Disease | Geriatric Disease

Denmark
Marius Henriksen

Completed

Comparison of Exercise Therapies for Patellofemoral Pain (COMPETE)

Patellofemoral Pain Syndrome

Denmark
Marius Henriksen

Completed

Saline Injections vs Education and Exercise in Knee Osteoarthritis (DISCO)

Osteoarthritis, Knee

Denmark
Marius Henriksen

Completed

Knee Replacement Outcome Predicted by Physiotherapists

Osteoarthritis | Total Knee Replacement

Denmark
Marius Henriksen

Completed

Progressive Active Exercise After Surgical Rotator Cuff Repair

Rotator Cuff Tear

Denmark
Marius Henriksen

Completed

Technology Assisted Physical Activity Among Hospitalised Patients With Respiratory Disease (TAPAS)

Respiratory Disease

Denmark
Marius Henriksen

Completed

Digital Motivation to Decrease Inactive Behaviour in Patients With Knee Osteoarthritis

Knee Osteoarthritis

Denmark
Marius Henriksen

Completed

Cannabidiol for Fibromyalgia (The CANNFIB Trial) (CANNFIB)

Fibromyalgia

Denmark
Marius Henriksen

Completed

Characteristics of Patients Declining INKA Trial Participation (n-INKA)

Knee Osteoarthritis

Denmark
Marius Henriksen

Terminated

SMS-based Lifestyle Intervention for Patients With Liver Cirrhosis With Previous Hepathic Encephalopathy (SMILE)

Liver Cirrhosis, Alcoholic

Denmark
Marius Henriksen

Terminated

Anti-il6 Treatment of Serious COVID-19 Disease With Threatening Respiratory Failure (TOCIVID)

Corona Virus Disease

Denmark
Marius Henriksen

Completed

Blood Pressure Changes During Moderate Intensity Strength Training in Aortic Stent-graft Patients

Aortic Stent Graft

Denmark
Marius Henriksen

Completed

Stretching and Pain Sensitivity

Stretching

Denmark
Matinas Biopharma, Inc

Completed

A PK and PD Study of Two Formulations of Omega-3 One Gram Capsules (PK/PD)

Hypertriglyceridemia

Canada
Matinas BioPharma Nanotechnologies, Inc.

Completed

Safety and Efficacy of Oral Encochleated Amphotericin B (CAMB/MAT2203) in the Treatment of Vulvovaginal Candidiasis (VVC)

Vulvovaginitis | Candidiasis, Vulvovaginal | Yeast Infection | Yeast Infection Vaginal

United States
Universidade Estadual de Maringá

Unknown

Effectiveness of Self-care Rests on Knowledge, Self-care and Cardiometabolic Control of Adult Men With Diabetes Mellitus

Diabetes Mellitus

Brazil
Universidade Estadual de Maringá

Unknown

Efficacy of N-Acetyl-Cysteine in Bipolar Disorder and Tobacco Use Disorder (NACBD)

Bipolar Disorder

Brazil
State University of Maringá

Completed

Short-term Changes on C-Reactive Protein (CRP) Levels After Non-surgical Periodontal Treatment

Chronic Periodontitis | Atherosclerotic Cardiovascular Disease

Brazil
Matinas BioPharma Nanotechnologies, Inc.

Completed

CAMB/MAT2203 in Patients With Mucocutaneous Candidiasis (CAMB)

Candidiasis, Chronic Mucocutaneous

United States
State University of Maringá

Completed

One Year Skeletal and Dental Arch Changes Following Rapid Maxillary Expansion Treatment in Children (ERM)

Cross-bite

Brazil
Centro Universitario de Maringa

Unknown

Global Posture Reeducation (GPR) Compared To Isostretching in Chronic Low Back Pain Patients

Low Back Pain

Brazil
Novartis Pharmaceuticals
Chugai Pharmaceutical

Completed

Study of Safety and Efficacy of Letrozole Monotherapy as Second-line Endocrine Therapy in Postmenopausal Patients With Advanced Breast Cancer Who Received Previous Anti-estrogen Treatment

Postmenopausal Women With Advanced Breast Cancer

Japan

Clinical Trials Sponsored by Marinus Pharmaceuticals

Sponsors and Collaborators

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