Clinical Trials Sponsored by Melrose Wakefield Hospital

Total 60 results

Baim Institute for Clinical Research
Lowell General Hospital; Metro West Medical Center; South Shore Hospital; Brockton... and other collaborators

Completed

Percutaneous Coronary Intervention (PCI) Outcomes in Community Versus Tertiary Settings (MASS COMM)

Coronary Artery Diseases

United States
Baim Institute for Clinical Research
Lowell General Hospital; Metro West Medical Center; South Shore Hospital; Brockton... and other collaborators

Completed

The MASS COMM Post-Randomization Phase Cohort Study

Coronary Artery Disease

United States
Bispebjerg Hospital
Royal Brompton & Harefield NHS Foundation Trust

Recruiting

A Comprehensive Evaluation of the Impact of ATP on Laryngeal Symptoms, Hypersensitivity and Function (MISP COUGH)

Chronic Refractory Cough

Denmark
Royal Brompton & Harefield NHS Foundation Trust
AHEPA University Hospital

Completed

a-Klotho in Relation to Calcification in the Coronary Arteries and Aortic Valve in Patients With Chronic Kidney Disease

Chronic Kidney Diseases | Vascular Calcification
Royal Brompton & Harefield NHS Foundation Trust
University Hospital Tuebingen

Terminated

Evaluating Additional Platelet Inhibition in Patients With High Platelet Reactivity Undergoing Percutaneous Coronary Intervention (APACS-HPR)

Cardiovascular Disease | Acute Coronary Syndrome

Germany
AHEPA University Hospital
Royal Brompton & Harefield NHS Foundation Trust

Completed

Post-operative Thoracic Epidural Analgesia and Incidence of Major Complications: a Large Retrospective Dual Center Experi-ence

Chronic Pain | Thoracic Cancer | Neuropathic Pain

Greece
Royal Brompton & Harefield NHS Foundation Trust
University Hospital, Basel, Switzerland; Bioxydyn Ltd, Manchester

Unknown

MRI in Cystic Fibrosis and Primary Ciliary Dyskinesia

Cystic Fibrosis | Primary Ciliary Dyskinesia

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
King's College Hospital NHS Trust; Imperial College London

Completed

A Study of Web and Tablet-based Interactive Audiometry in Adults With CF

Cystic Fibrosis | Hearing Loss, Sensorineural

United Kingdom
University Hospital Tuebingen
Royal Brompton & Harefield NHS Foundation Trust; National Heart and Lung Institute

Recruiting

Monocentric Registry to Investigate the Role of Platelet Function, Platelet Genetics, Proteomics and Metabonomics in Heart Disease (TuePIC)

Cardiovascular Disease

Germany
Royal Brompton & Harefield NHS Foundation Trust
Oxford University Hospitals NHS Trust; Sherwood Forest Hospitals NHS Foundation...

Unknown

Ballooned Intercostal Drain Trial

Pneumothorax | Pleural Effusion

United Kingdom
Nottingham University Hospitals NHS Trust
University of Washington; Seattle Children's Hospital; The Leeds Teaching Hospitals... and other collaborators

Active, not recruiting

CFTR Modulators and Gastrointestinal Complications (CFTR-MAGIC)

Lung Diseases | Cystic Fibrosis | Digestive System Disease | Pancreatic Disease | Distal Intestinal Obstruction Syndrome | Pancreatic Enzyme Abnormality | Gastrointestinal System Disease

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Medical Research Council; The Hillingdon Hospitals NHS Foundation Trust

Terminated

Post-hospitalisation Nutritional Support and Gait Speed in COPD

Respiratory Tract Diseases | Lung Diseases, Obstructive | Pulmonary Disease, Chronic Obstructive | Pulmonary Emphysema | Bronchitis, Chronic

United Kingdom
Barts & The London NHS Trust
University College London Hospitals; Royal Brompton & Harefield NHS Foundation...

Completed

Bone Marrow Derived Adult Stem Cells for Dilated Cardiomyopathy (REGEN-DCM)

Dilated Cardiomyopathy

United Kingdom
University of Kent
King's College Hospital NHS Trust; Royal Brompton & Harefield NHS Foundation... and other collaborators

Completed

Do Heat and Moisture Exchange Mask Reduce EIB and Cough Severity in Asthma

Asthma | Asthma, Exercise-Induced
Royal Brompton & Harefield NHS Foundation Trust
Brighton and Sussex University Hospitals NHS Trust; Liverpool Heart and Chest...

Completed

Long-term Outcomes in Long Standing Persistent Atrial Fibrillation (LoTO_CASA_AF)

Long Standing Persistent Atrial Fibrillation

United Kingdom
University of Edinburgh
Royal Brompton & Harefield NHS Foundation Trust; Royal Infirmary of Edinburgh; Golden Jubilee National Hospital

Completed

DEtection of Cellular Inflammation With FERumoxytol in the HEART (DECIFER)

Myocarditis | Healthy Volunteers | Cardiac Transplant | Cardiac Sarcoid

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Medical Research Council; The Hillingdon Hospitals NHS Foundation Trust; West...

Completed

Do the SPPB and 4-metre Gait Speed Predict Hospital Readmission in Patients Hospitalised for Acute Exacerbation if COPD?

Respiratory Tract Diseases | Lung Diseases | Disease Progression | Lung Diseases, Obstructive | Pulmonary Disease, Chronic Obstructive | Pulmonary Emphysema | Bronchitis, Chronic

United Kingdom
Imperial College London
Nottingham University Hospitals NHS Trust; Royal Brompton & Harefield NHS Foundation... and other collaborators

Not yet recruiting

Nebulised Hypertonic Saline to Decrease Respiratory Exacerbations in Neuromuscular Disease or Neurodisability (SPICE-UP)

Cerebral Palsy | Neuromuscular Diseases | Neurodevelopmental Disorders

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
University College London Hospitals; Guy's and St Thomas' NHS Foundation Trust

Recruiting

Connecting Breath and Mind for CYP With Long COVID

Anxiety | Post-COVID-19 Syndrome | Breathlessness

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
University College London Hospitals; Imperial College London; University of East...

Completed

Rituximab Versus Cyclophosphamide in Connective Tissue Disease-ILD (RECITAL)

Interstitial Lung Disease | Scleroderma | Idiopathic Inflammatory Myositis | Mixed Connective Tissue Disease

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College Hospital NHS Trust; Royal Brompton & Harefield NHS Foundation... and other collaborators

Not yet recruiting

Haemodynamics of Mitral Regurgitation Reduction (STRESS-MR)

Mitral Regurgitation
Imperial College London
Royal Brompton & Harefield NHS Foundation Trust; Great Ormond Street Hospital...

Recruiting

Inherited Cardiac cONditions In Kids (ICONIK)

Cardiovascular Diseases | Inherited Cardiac Conditions

United Kingdom
European Georges Pompidou Hospital
University Hospital, Geneva; KU Leuven; Erasmus Medical Center; Centre Hospitalier... and other collaborators

Completed

Sudden Cardiac Death in Systemic Right Ventricle (STARSII)

Congenital Heart Disease | Transposition of Great Vessels | Sudden Cardiac Death

France
Royal Brompton & Harefield NHS Foundation Trust
Liverpool University Hospitals NHS Foundation Trust; National Institute for...

Completed

Ambulatory Oxygen in Fibrotic Lung Disease (FLD) (AmbOx) (AmbOx)

Lung; Disease, Fibroid (Chronic)

United Kingdom
Erasmus Medical Center
King's College Hospital NHS Trust; Royal Brompton & Harefield NHS Foundation... and other collaborators

Completed

The Effect of Pirfenidone on Cough in Patients With Idiopathic Pulmonary Fibrosis (Cough-IPF)

Idiopathic Pulmonary Fibrosis

France, Italy, Netherlands
Papworth Hospital NHS Foundation Trust
King's College Hospital NHS Trust; The Leeds Teaching Hospitals NHS Trust; University... and other collaborators

Completed

Home Monitoring to Predict Exacerbation in Cystic Fibrosis (SmartCare)

Cystic Fibrosis

United Kingdom
University of Aarhus
The Hospital for Sick Children; Royal Brompton & Harefield NHS Foundation Trust and other collaborators

Completed

Remote Ischemic Preconditioning in Primary PCI

Myocardial Infarction

Denmark
Guy's and St Thomas' NHS Foundation Trust
King's College London; King's College Hospital NHS Trust; Royal Brompton & Harefield...

Completed

Domiciliary Transcutaneous Electrical Stimulation in Obstructive Sleep Apnoea (TESLA-home)

Obstructive Sleep Apnea

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Liverpool Heart and Chest Hospital NHS Foundation Trust; National Institute...

Unknown

Catheter Ablation Versus Thoracoscopic Surgical Ablation in Long Standing Persistent Atrial Fibrillation (CASA-AF) (CASA-AF)

Persistent Atrial Fibrillation

United Kingdom
Nottingham University Hospitals NHS Trust
King's College Hospital NHS Trust; The Leeds Teaching Hospitals NHS Trust; Manchester... and other collaborators

Recruiting

A Comprehensive Approach To Relief Of Digestive Symptoms In Cystic Fibrosis: CARDS-CF (CARDS-CF)

Respiratory Tract Diseases | Lung Diseases | Cystic Fibrosis | Genetic Disease | Digestive System Disease | Pancreatic Disease

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
GlaxoSmithKline; University of Cambridge; Royal Brompton & Harefield NHS Foundation... and other collaborators

Completed

Losmapimod in Chronic Obstructive Pulmonary Disease Patients Stratified by Fibrinogen. (EVOLUTION)

Chronic Obstructive Pulmonary Disease

United Kingdom
Odense University Hospital
Charite University, Berlin, Germany; Hannover Medical School; Aarhus University... and other collaborators

Completed

Danish Cardiogenic Shock Trial (DanShock)

Acute Myocardial Infarction | Cardiogenic Shock Acute

Germany, Denmark, United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
King's College London; King's College Hospital NHS Trust; Imperial College London and other collaborators

Active, not recruiting

Validation of an Artificial Intelligence Enabled Diagnostic Support Software (ArtiQ.Spiro) in Primary Care Spirometry Datasets - a Retrospective Analysis

Respiratory Disease

United Kingdom
corlife
Universitaire Ziekenhuizen KU Leuven; Hannover Medical School; Hospital Clinic... and other collaborators

Completed

Aortic Replacement Using Individualised Regenerative Allografts - ARISE (the "Surveillance") (ARISE)

Heart Valve Disease

Germany, Switzerland, Belgium, Italy, Netherlands, Spain, United Kingdom
Liverpool Heart and Chest Hospital NHS Foundation...
Guy's and St Thomas' NHS Foundation Trust; University Hospital Birmingham NHS... and other collaborators

Withdrawn

Reduction in Arrhythmia Burden With Left Atrial Posterior Wall Ablation for Persistent AF (RABLAP-AF)

Atrial Fibrillation

United Kingdom
Imperial College London
University Hospitals, Leicester; Medical University of Silesia; Royal Brompton... and other collaborators

Completed

Randomised Ischaemic Mitral Evaluation (RIME) Trial (RIME)

Coronary Artery Disease | Mitral Regurgitation

United Kingdom, Poland
Tenaya Therapeutics
Medical University of South Carolina; Johns Hopkins University; University of... and other collaborators

Recruiting

Non-interventional Study of Seroprevalence of Pre-existing Antibodies Against Adenovirus-associated Virus Vector (AAV9) and the Progression of Disease in Patients With Plakophilin 2 (PKP2)-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) (RIDGE)

Arrhythmogenic Right Ventricular Cardiomyopathy

United States, Italy, United Kingdom, France, Sweden, Germany
University of Cambridge
Guy's and St Thomas' NHS Foundation Trust; Manchester University NHS Foundation... and other collaborators

Completed

Observational Cohort Study of a National Extracorporeal Membrane Oxygenation Service for Adults With Respiratory Failure: the NHS ECMO Study. (NHS ECMO)

Acute Respiratory Failure
Royal College of Surgeons, Ireland
The Hospital for Sick Children; Massachusetts General Hospital; Belfast Health... and other collaborators

Not yet recruiting

ENHANCE- Establishing Natural History in an Advanced New CF Care Era

Cystic Fibrosis
Queen's University, Belfast
The Leeds Teaching Hospitals NHS Trust; Cambridge University Hospitals NHS... and other collaborators

Recruiting

Co-morbidity and Refractory Asthma - UK Severe Asthma Registry (UKSAR)

Asthma

United Kingdom
Imperial College London
Guy's and St Thomas' NHS Foundation Trust; Liverpool University Hospitals NHS... and other collaborators

Recruiting

Coronary Sinus Reducer Implantation in Patients With Ischaemia and Non-obstructed Coronary Arteries and Coronary Microvascular Dysfunction. (REMEDY-PILOT)

Coronary Disease | Angina Pectoris | Refractory Angina | Microvascular Angina | Microvascular Coronary Artery Disease

United Kingdom
Sheffield Hallam University
AstraZeneca; Belfast Health and Social Care Trust; Sheffield Teaching Hospitals... and other collaborators

Recruiting

Optimising Secondary Prevention and Quality of Life in Early Cardiac Rehabilitation (OSPREY-CR)

Myocardial Infarction | Cardiovascular Diseases | Coronary Artery Disease | Heart Failure | Coronary Heart Disease | Acute Coronary Syndrome

United Kingdom
TransMedics
Massachusetts General Hospital; University of California, Los Angeles; Columbia... and other collaborators

Completed

Randomized Study of Organ Care System Cardiac for Preservation of Donated Hearts for Eventual Transplantation (PROCEEDII)

Heart Failure

United States, United Kingdom, France, Italy
Queen's University, Belfast
Medical Research Council; Belfast Health and Social Care Trust; NHS Lothian; University... and other collaborators

Completed

Clinimetric Properties of Outcome Measures in Bronchiectasis in the UK

Bronchiectasis

United Kingdom
The First Affiliated Hospital with Nanjing Medical...
National University Hospital, Singapore; University of Pennsylvania; General... and other collaborators

Unknown

CPVI Alone Versus. CPVI Plus Electrophysiological Substrate Ablation in the LA During SR for the Treatment of Non-PAF (STABLE-SR_II)

Atrial Fibrillation

China
Guy's and St Thomas' NHS Foundation Trust
London School of Hygiene and Tropical Medicine; King's College London; King's... and other collaborators

Completed

A Randomised Trial of Expedited Transfer to a Cardiac Arrest Centre for Non-ST Elevation Out-of-hospital Cardiac Arrest (ARREST)

Out-Of-Hospital Cardiac Arrest

United Kingdom
University of Southampton
Assistance Publique - Hôpitaux de Paris; Hacettepe University; Universitaire... and other collaborators

Unknown

PRospective Observational Multicentre Study on VAriability of Lung Function in Stable PCD Patients (PROVALF-PCD)

Primary Ciliary Dyskinesia

United Kingdom
Royal Marsden NHS Foundation Trust
King's College Hospital NHS Trust; University College London Hospitals; Imperial... and other collaborators

Recruiting

Nodule IMmunophenotyping Biomarker for Lung Cancer Early Diagnosis Study

Lung Cancer

United Kingdom
University College, London
University of Nottingham; Imperial College London; Cambridge University Hospitals... and other collaborators

Unknown

The MRC/ABPI COPD Cohort v1.7 (COPDMAP)

COPD

United Kingdom
Royal Marsden NHS Foundation Trust
King's College Hospital NHS Trust; University College London Hospitals; Guy's... and other collaborators

Recruiting

Lung Nodule Imaging Biobank for Radiomics and AI Research (LIBRA)

Lung Neoplasms | Lung Cancer | Pulmonary Nodule, Solitary | Pulmonary Nodule, Multiple

United Kingdom

Clinical Trials Sponsored by Melrose Wakefield Hospital

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