Clinical Trials Sponsored by N.M. Wulffraat

Total 491 results

N.M. Wulffraat

Completed

Treatment of Steroid Resistant GVHD by Infusion MSC (MSCforGVHD)

Graft-versus-host-disease

Netherlands
N.M. Wulffraat
National Institute for Public Health and the Environment (RIVM)

Completed

Immune Response After Human Papillomavirus Vaccination in Patients With Autoimmune Disease (HPV-kind)

Systemic Lupus Erythematosus | Juvenile Idiopathic Arthritis | Juvenile Dermatomyositis

Netherlands
N.M. Wulffraat
University Medical Center Groningen; Maastricht University Medical Center; Erasmus... and other collaborators

Completed

Safety and Efficacy of Measles, Mumps, Rubella Vaccination in Juvenile Idiopathic Arthritis (VAART)

Arthritis, Juvenile Rheumatoid

Netherlands
Comenius University
Sanatórium of Dr. Guhr, n.o.; Kaneka Pharma Europe N.V.

Completed

Spa Rehabilitation, Antioxidant and Bioenergetic Supportive Treatment of Patients With Post-Covid-19 Syndrome (SpaCOVID)

COVID-19 Respiratory Infection

Slovakia
PharmaNeuroBoost N.V.

Completed

Pipamperone/Citalopram (PNB01) Versus Citalopram (CIT) and Versus Pipamperone (PIP) in Major Depressive Disorder (MDD)

Major Depressive Disorder

United States, Canada
PharmaNeuroBoost N.V.

Completed

POC Study of Pipamperone Added to Stable Treatment With RIS or PAL in Chronic Schizophrenia

Schizoaffective Disorder | Chronic Schizophrenia

Belgium
ActoGeniX N.V.

Completed

Study to Assess Safety and Tolerability of AG013 in Oral Mucositis in Subjects Receiving Induction Chemotherapy for the Treatment of Cancers of the Head and Neck

Oral Mucositis

United States
ActoGeniX N.V.

Completed

A Phase 2a Study to Evaluate the Safety, Tolerability, Pharmacodynamics and Efficacy of AG011 in Ulcerative Colitis

Moderately Active Ulcerative Colitis

Canada, Netherlands, Sweden, Belgium
Recoly N.V.

Completed

Study of the Efficacy of Human Recombinant Factor VIII (Kogenate FS) Reconstituted in Pegylated Liposomes.

Haemophilia A

Russian Federation
Merus N.V.

Recruiting

Study Evaluating Zenocutuzumab in Patients With or Without Molecularly Defined Cancers

Metastatic Castration-resistant Prostate Cancer | NSCLC Harboring NRG1 Fusion

United States
Adenobio N.V

Unknown

Phase II Study for the Diagnosis and Functional Assessment of CAD Using Transthoracic-Echodoppler

Ischemic Heart Disease

France
TiGenix n.v.

Terminated

A Prospective, Post-marketing Registry on the Use of ChondroMimetic for the Repair of Osteochondral Defects (OMCM)

Osteochondral Defects

United Kingdom, Germany, Hungary, Belgium
PharmaNeuroBoost N.V.

Completed

Pipamperone/Citalopram (PipCit)Versus Citalopram in the Treatment of Major Depressive Disorder(MDD)

Depression

United Kingdom
Merus N.V.

Recruiting

A Phase 1/2 Study Evaluating MCLA-129, a Human Anti-EGFR and Anti-c-MET Bispecific Antibody, in Patients With Advanced NSCLC and Other Solid Tumors

Gastric Cancer | Head and Neck Squamous Cell Carcinoma | Esophageal Squamous Cell Carcinoma | Non-Small Cell Lung Cancer Metastatic

United States, Spain, France, Italy, Netherlands, Belgium, Korea, Republic of, Germany, Singapore
Merus N.V.

Recruiting

A Study of Zenocutuzumab (MCLA-128) in Patients With Solid Tumors Harboring an NRG1 Fusion (eNRGy)

NSCLC Harboring NRG1 Fusion | Solid Tumours Harboring NRG1 Fusion | Pancreatic Cancer Harboring NRG1 Fusion | NRG1 Fusion

Spain, France, Israel, Belgium, Denmark, United States, Korea, Republic of, Japan, Germany, Netherlands, Austria, Canada, Italy, Norway, Singapore, Sweden, Taiwan, United Kingdom
Merus N.V.

Completed

MCLA-128 With Trastuzumab/Chemotherapy in HER2+ and With Endocrine Therapy in ER+ and Low HER2 Breast Cancer.

Breast Cancer Metastatic

United States, France, Belgium, Spain, United Kingdom, Netherlands, Portugal
Merus N.V.

Available

Early Access Program Providing HER2/HER3 Bispecific Antibody, MCLA-128, for a Patient With Advanced NRG1-Fusion Positive Solid Tumor

Renal Cell Carcinoma | Breast Cancer | Head and Neck Cancer | Colorectal Cancer | Pancreatic Cancer | Prostate Cancer | Non Small Cell Lung Cancer | Cholangiocarcinoma | Solid Tumor, Unspecified, Adult | Unknown Primary Tumors | NRG1 Fusion
Merus N.V.

Active, not recruiting

MCLA-117 in Acute Myelogenous Leukemia

Acute Myeloid Leukemia | Acute Myelogenous Leukemia

United States, Italy, Netherlands, Belgium, France
TiGenix n.v.

Completed

RCT of ChondroCelect® (in an ACI Procedure) vs Microfracture in the Repair of Cartilage Defects of the Knee (TIGACT01)

Articular Cartilage Lesion of the Femoral Condyle

Belgium, Croatia, Germany, Netherlands
NGM Biopharmaceuticals, Inc
NGM Biopharmaceuticals Australia Pty Ltd

Completed

Phase 2 Study of NGM282 in Patients With Type 2 Diabetes

Diabetes Mellitus

Australia, New Zealand
S.M. Misericordia Hospital

Recruiting

RObotic Versus LAparoscopic Colectomy for DIverticulitis. (ROLADI)

Diverticulitis | Diverticular Diseases

Italy
Terumo Europe N.V.

Recruiting

Holmium-166 Transarterial Radioembolization in Unresectable, Early Stage Hepatocellular Carcinoma. (HOMIE-166)

Hepatocellular Carcinoma

Germany
NGM Biopharmaceuticals, Inc

Completed

Study of Aldafermin (NGM282) in Participants With Impaired Hepatic Function

Impaired Hepatic Function

United States
NGM Biopharmaceuticals, Inc

Completed

Study of NGM395 in Adult Participants

Obesity | NAFLD

Australia
Sequana Medical N.V.

Withdrawn

Optimal Balance Alfapump® System Feasibility Study (OPTIMALBALANCE)

Heart Failure

Hungary
Sequana Medical N.V.

Completed

ALFApump System Post Marketing Surveillance Registry (2011-AAR-004)

Liver Cirrhosis | Malignant Ascites | Refractory Ascites

Germany, Switzerland, Spain, United Kingdom
Terumo Europe N.V.

Completed

e-NOBORI Observational Registry of Nobori DES (e-NOBORI)

Coronary Artery Disease

Ireland, France, Taiwan, Spain, United Kingdom, Israel, Netherlands, Czechia, Sweden, Bangladesh, Russian Federation, Brazil, Bulgaria, Serbia, Chile, Germany, Hungary, Indonesia, Georgia, Austria, Belarus, Denmark, Egypt, Estonia, Latvia, Lithuan... and more
Terumo Europe N.V.

Unknown

Prospective, Single-arm, Multi Centre Observations Ultimaster Des Registry (e-Ultimaster)

Coronary Artery Disease

Netherlands, France, United Kingdom, Austria, Ireland, Spain, Bulgaria, South Africa, Israel, Hungary, Switzerland, Chile, Belgium, Japan, Argentina, Portugal, United Arab Emirates, Serbia, Malaysia, Brazil, India, Poland, Indonesia, ... and more
Terumo Europe N.V.

Completed

Optical Frequency Domain Imaging (OFDI) Assessed Strut Coverage of New Terumo DES (DISCOVERY123)

Coronary Artery Disease

France, Netherlands, Germany
NGM Biopharmaceuticals, Inc

Completed

Single and Multiple Ascending Dose Study of NGM120 in Healthy Adult Subjects

Cachexia

Australia
NGM Biopharmaceuticals, Inc

Completed

Study of NGM313 in Obese Participants

Obese

United States
Trod Medical N.V.

Unknown

Focal Prostate Radiofrequency Ablation (ProRAFT)

Prostate Cancer

United Kingdom
Sequana Medical N.V.

Completed

A (M)Ulti-center, Prospective, (O)Pen Label, Uncontrolled Feasibility (S)Tudy to Assess the Safety and Effectiveness of an Automatic Low Flow (A)Scites (Alfa) Pump (I)n Patients With (C)Irrhosis and Refractory or Recurrent Ascites (MOSAIC)

Cirrhosis | Ascites

Canada, United States
NGM Biopharmaceuticals, Inc

Completed

Phase 1 Study of NGM313 in Healthy Adult Participants

Obesity

Australia
Sequana Medical N.V.

Unknown

Effects of Treatment of Ascites by the ALFApump System on Renal and Circulatory Function

Cirrhosis, Liver | Refractory Ascites

Spain
S.M. Misericordia Hospital

Completed

Microcirculation Assessment in Diabetes and Metabolic Syndrome (MADAME)

Diabetes | Metabolic Syndrome | Coronary Microvascular Dysfunction

Italy
Aqumen Biopharmaceuticals, N.A.

Completed

DY001: Safety and Effectiveness of DYME as an Agent for Selective Staining of the Anterior Capsule During Cataract Surgery

Mature Cataracts

United States, India
NGM Biopharmaceuticals, Inc
NGM Biopharmaceuticals Australia Pty Ltd

Completed

Study of NGM282 in Patients With Nonalcoholic Steatohepatitis (NASH)

Nonalcoholic Steatohepatitis (NASH)

United States, Australia, Puerto Rico
NGM Biopharmaceuticals, Inc
NGM Biopharmaceuticals Australia Pty Ltd

Completed

Phase 2b Study of NGM282 Extended Treatment in Patients With Primary Biliary Cirrhosis

Primary Biliary Cirrhosis

United States, Australia, New Zealand
Sequana Medical N.V.

Recruiting

Management of Volume Overload HF Patients by Individual DSR Treatment adJustment-a clinicAl inVestigation of InfusatE2.0 (MOJAVE)

Heart Failure | Volume Overload

United States
Terumo Europe N.V.

Recruiting

Ultimaster Nagomi™ Sirolimus Eluting Coronary Stent System in Complex PCI Patients (NAGOMI COMPLEX)

Cardiovascular Disease | Ischemic Heart Disease | Coronary Artery Occlusion

Switzerland, Spain, Netherlands, Belgium, United Kingdom, Ireland, Italy, Estonia
Terumo Europe N.V.

Active, not recruiting

Prospective Multicenter Study to Confirm the Performance of the Renzan Stent in Treatment of SFA/POP Artery Disease (PRIZER)

Superficial Femoral Artery Disease | Popliteal Artery Disease

Spain, Belgium, Germany, France, Netherlands
NGM Biopharmaceuticals, Inc

Completed

A Study of NGM621 in Participants With Geographic Atrophy (CATALINA)

Geographic Atrophy

United States
Terumo Europe N.V.

Completed

Holmium-166 Retrospective Collection of Real-World Data (RECORD)

Hepatocellular Carcinoma | Metastatic Cancer

Netherlands, Germany, Switzerland, Belgium, Spain, Portugal, Italy
Terumo Europe N.V.

Terminated

QuiremSpheres Observational Study (Hope166)

Liver, Cancer of, Non-Resectable

Netherlands, Germany
NGM Biopharmaceuticals, Inc

Completed

Study of NGM621 in Participants With Geographic Atrophy

Geographic Atrophy

United States
Sequana Medical N.V.

Withdrawn

Malignant Ascites Alfapump® Study (ProMAS)

Malignant Ascites

United Kingdom
NGM Biopharmaceuticals, Inc

Completed

Study of Aldafermin (NGM282) in Participants With Impaired Renal Function

Impaired Renal Function

United States
Terumo Europe N.V.

Completed

Safety and Efficacy Study of Kaname Coronary Stent System for the Treatment of Patients With Coronary Artery Disease (KARE)

Coronary Artery Disease | Angioplasty, Transluminal, Percutaneous Coronary

Spain, Germany, Serbia, France, Italy
Terumo Europe N.V.

Completed

Safety and Efficacy of TCD-10023 (Ultimaster) Drug-eluting Stent in STEMI Patients - MASTER Study (MASTER)

Acute ST Segment Elevation Myocardial Infarction

Brazil, Serbia, Italy, Spain, Macedonia, The Former Yugoslav Republic of

Clinical Trials Sponsored by N.M. Wulffraat

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