Clinical Trials Sponsored by NYSTAR

Total 190 results

Medical Acoustics LLC
NYSTAR

Completed

Impact of Lung Flute Therapy on Asthma

Persistent Asthma

United States
Nektar Therapeutics

Completed

NKTR-255 in Relapsed/Refractory Multiple Myeloma & Non-Hodgkin Lymphoma

Multiple Myeloma | Non-Hodgkin Lymphoma | Indolent Non-Hodgkin Lymphoma

United States
Nektar Therapeutics

Completed

A Study of Etirinotecan Pegol (NKTR-102) Versus Treatment of Physician's Choice (TPC) in Patients With Metastatic Breast Cancer Who Have Stable Brain Metastases and Have Been Previously Treated With an Anthracycline, a Taxane, and Capecitabine (ATTAIN)

Breast Cancer | Metastasis

United States, Australia, Belgium, Canada, France, Israel, Italy, Portugal, Spain, United Kingdom
Nektar Therapeutics

Completed

Study to Evaluate the Safety and Efficacy of NKTR-102 in Patients With Metastatic or Locally Advanced Ovarian Cancer

Ovarian Cancer | Tumor

United States, Belgium, United Kingdom
Nektar Therapeutics

Completed

NKTR-102 in Combination With Cetuximab in Patients With Refractory Solid Tumors (Phase 2a) and Metastatic or Locally Advanced Colorectal Cancer (Phase 2b)

Colorectal Cancer | Tumor

United States
Nektar Therapeutics

Completed

Long-Term Safety and Tolerability Study of NKTR-181 in Subjects With Chronic Low Back Pain or Chronic Non-Cancer Pain (SUMMIT-LTS)

Low Back Pain | Chronic Pain

United States
Nektar Therapeutics

Completed

Study to Evaluate the Safety and Efficacy of NKTR-102 in Patients With Metastatic or Locally Advanced Breast Cancer

Breast Cancer | Tumor

United States, Belgium, United Kingdom
Nektar Therapeutics

Completed

A Study in Cancer Patients With Hepatic Impairment to Evaluate the Pharmacokinetics and Safety of NKTR-102 (Etirinotecan Pegol)

Advanced or Metastatic Solid Tumors in Patients With Hepatic Impairment

United States
Nektar Therapeutics

Recruiting

A Phase 2b Study to Evaluate Rezpegaldesleukin (Rezpeg) in the Treatment of Adult Patients With Moderate-to-Severe Atopic Dermatitis (REZOLVE-AD)

Moderate to Severe Atopic Dermatitis

United States, Canada
Nektar Therapeutics

Recruiting

NKTR-255 vs Placebo Following CD19-directed CAR-T Therapy in Patients With Relapsed/Refractory Large B-cell Lymphoma

Non-Hodgkin Lymphoma | Relapsed/Refractory Diffuse Large B-cell Lymphoma

United States
Nektar Therapeutics

Completed

A Placebo Controlled Trial of Bempegaldesleukin (BEMPEG; NKTR-214) With Standard of Care in Patients With Mild COVID-19

Covid-19 | Coronavirus Disease 2019

United States
Nektar Therapeutics

Terminated

Bempegaldesleukin and Pembrolizumab With or Without Chemotherapy in Locally Advanced or Metastatic Solid Tumors (PROPEL)

Non-Small Cell Lung Cancer

United States, Germany, Spain, Australia, France
Nektar Therapeutics

Completed

A Phase 2 Study To Assess The Efficacy, Tolerability, And Safety OF NKTR-181 In Subjects With Chronic OA Knee Pain

Osteoarthritis of the Knee

United States
Nektar Therapeutics

Completed

A Phase 1/2 Multicenter Dose Escalation and Expansion Study Of NKTR-214 In Subjects With Locally Advanced Or Metastatic Solid Tumors (NKTR-214)

Unspecified Adult Solid Tumor, Protocol Specific

United States
Nektar Therapeutics

Completed

An Extension Study of NKTR-102 in Cancer Patients Previously Enrolled in NKTR-102 Studies

Malignant Solid Tumor

United States, Belgium
Nektar Therapeutics

Completed

Efficacy and Safety Study of NKTR-181 in Opioid-Naive Subjects With Low Back Pain (SUMMIT-07)

Low Back Pain | Chronic Pain

United States
Nektar Therapeutics

Completed

A Study in Cancer Patients to Evaluate the Effect of a Single Dose of NKTR-102 (Etirinotecan Pegol) on the QTc Interval and to Assess Pharmacokinetics and Safety

Advanced Cancer | Metastatic Solid Tumors

United States
Nektar Therapeutics

Recruiting

A Phase 2b Study to Evaluate Rezpegaldesleukin (Rezpeg) in the Treatment of Severe to Very Severe Alopecia Areata in Adult Patients (Rezolve AA)

Alopecia Areata

United States
Nektar Therapeutics

Completed

Study of NKTR 255 in Combination With Cetuximab in Solid Tumors

Cervical Cancer | Colorectal Cancer | Head and Neck Squamous Cell Carcinoma | Anal Squamous Cell Carcinoma | Cutaneous Squamous Cell Carcinoma

United States
Nektar Therapeutics

Terminated

A Study of NKTR-262 in Combination With Bempegaldesleukin (NKTR-214) and With Bempegaldesleukin Plus Nivolumab in Patients With Locally Advanced or Metastatic Solid Tumor Malignancies (REVEAL)

Melanoma | Sarcoma | Renal Cell Carcinoma | Colorectal Cancer | Triple Negative Breast Cancer | Head and Neck Squamous Cell Carcinoma | Merkel Cell Carcinoma

United States
Nektar Therapeutics

Completed

NKTR-102 Versus Irinotecan in Patients With Second-Line, Irinotecan-Naïve, KRAS Mutant, Colorectal Cancer

Colorectal Cancer

United States, Belgium, Germany, India, Spain, United Kingdom
Nektar Therapeutics

Terminated

A Study Using fMRI Imaging to Evaluate the Effect of NKTR-181 on Brain Activity in Healthy, Non-physically Dependent Recreational Opioid Users.

Moderate to Severe Chronic Pain

United States
Nektar Therapeutics

Completed

The BEACON Study (Breast Cancer Outcomes With NKTR-102) (BEACON)

Metastatic Breast Cancer | Locally Recurrent Breast Cancer

United States, Spain, Korea, Republic of, Canada, United Kingdom, Germany, France, Netherlands, Belgium, Italy, Russian Federation
University of Mostar

Not yet recruiting

The Effect of Low Doses of Prednisone on the Prolongation of Pregnancy in Threatened Preterm Birth

Preterm Birth
University of Mostar

Completed

Prognostic Value of Protein IMP3 Expression in Cervical Cancer

Cervical Carcinoma
Nishtar Medical University

Completed

Early Functional Outcomes in Unisplaced Neck of Femur Fracture Treated With Partially Threaded and Fully Threaded Cannulated Screw Fixation in Patients of Age 60 and Above

Neck of Femur Fracture

Pakistan
Nishtar Medical University

Completed

Efficacy of Letrozole Versus Clomiphene Citrate on Ovulation Induction in Patients With Polycystic Ovarian Syndrome

Polycystic Ovary Syndrome

Pakistan
Nishtar Medical University

Completed

Role of Folinic Acid in Improving the Adaptive Skills and Language Impairment in Children With Autism Spectrum Disorder

Autism Spectrum Disorder

Pakistan
University of Mostar

Completed

Relationship of Reduced Arterial Stiffness and Hs-CRP With GDM.

Gestational Diabetes

Bosnia and Herzegovina
University of Mostar

Completed

MTHFR Mutation and Concentration of B12,Folic Acid,Homocysteine and HS CRP in the Blood of Pregnant Women With GDM.

Gestational Diabetes

Bosnia and Herzegovina
Nishtar Medical University

Completed

Role of Montelukast in Preventing Relapse in Childhood Idiopathic Nephrotic Syndrome

Nephrotic Syndrome

Pakistan
University of Mostar

Unknown

The Relation Between Midwifery Education and Listening to Classical Music With the Mode of Delivery

Pain Score | Apgar Score | Mental Health Issue | Delivery Mode | Breastfeeding Rate

Bosnia and Herzegovina
Bayer
Nektar Therapeutics

Completed

Inhaled Amikacin Solution BAY41-6551 as Adjunctive Therapy in the Treatment of Gram-Negative Pneumonia (INHALE 1)

Pneumonia, Bacterial

Korea, Republic of, Taiwan, United States, Canada, Philippines, Turkey, Thailand, Australia, Mexico, Colombia, Czechia, Brazil
The Wistar Institute

Completed

Immune and Viral Outcomes of HIV-1 Therapy Interruption

HIV Infections

United States
AstraZeneca
Nektar Therapeutics

Completed

A Phase 2, Double-Blind, Multiple-Dose Escalation Study to Evaluate NKTR-118 (Oral PEG-Naloxol) in Patients With Opioid-Induced Constipation (OIC)

Opioid Induced Constipation (OIC)

United States
iSTAR Medical

Completed

MINIject in Patients With Open Angle Glaucoma Using Single Operator Delivery Tool

Glaucoma, Open-Angle | Glaucoma Eye

Panama, Colombia, India
iSTAR Medical

Active, not recruiting

STAR-LIFE Registry: STARflo Glaucoma Implant Clinical Experience Program

Open Angle Glaucoma

Spain, Germany, Belgium, France, Hungary
iSTAR Medical

Completed

STARflo European Safety and Efficacy Study

Open Angle Glaucoma

Belgium, Germany, Bulgaria, France, Switzerland
Nishtar Medical University

Completed

Medical Treatment in Ectopic Tubal Pregnancy

Ectopic Pregnancy

Pakistan
Bayer
Nektar Therapeutics

Completed

Safety, Tolerability and Pharmacokinetics of Aerosolized Amikacin in Intubated and Mechanically-ventilated Patients With Nosocomial Pneumonia

Pneumonia

United States, France
The Wistar Institute

Completed

Anti-HIV Treatment Interruptions in HIV Infected Adults in South Africa

HIV Infections

South Africa
Bayer
Nektar Therapeutics

Completed

A Study to Determine the Correct Dose of Amikacin Which is Delivered Directly to the Lungs of Ventilated Patients as an Aerosol Via an Investigational Device Called the Pulmonary Delivery Device System (PDDS)

Pneumonia

France, Spain, United States
iSTAR Medical

Recruiting

Evaluate the Safety and Effectiveness of iSTAR Medical's MINIject™ Implant for Lowering Intraocular Pressure (IOP) in Subjects With Primary Open-angle Glaucoma. (STAR-V)

Glaucoma

United States
iSTAR Medical

Recruiting

MINIject Global Long-Term Follow-up Study (STAR-GLOBAL)

Ocular Hypertension | Open Angle Glaucoma

Germany, Spain, Colombia, France, India, Panama
iSTAR Medical

Enrolling by invitation

MINIject Implantation Combined With Cataract Surgery in Patients With POAG and Cataract (STAR-VI)

Cataract | Primary Open-angle Glaucoma

Spain, Panama, United Kingdom
iSTAR Medical

Completed

MINIject Glaucoma Implant in European Patients (STAR-II)

Glaucoma, Open-Angle | Intraocular Pressure | Glaucoma Eye

France, Germany, Spain
iSTAR Medical

Completed

MINIject in Patients With Open Angle Glaucoma Uncontrolled by Topical Hypotensive Medications (STAR-I)

Open Angle Glaucoma

India, Panama
iSTAR Medical

Recruiting

STAR-LIFE: a Post-market Registry on MINIject (STAR-LIFE)

Open Angle Glaucoma

Switzerland
iSTAR Medical

Completed

MINIject 636 in Patients With Open Angle Glaucoma Uncontrolled by Topical Hypotensive Medications

Open Angle Glaucoma

Colombia, India, Panama
Oyster Point Pharma, Inc.

Completed

Evaluating Relative Bioavailability of OC-01 (Varenicline) Nasal Spray as Compared to Orally Administered Varenicline

Healthy Subjects

United States

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