Clinical Trials Sponsored by National Pediatric Cancer Foundation

Total 900 results

Nationwide Children's Hospital
National Pediatric Cancer Foundation

Recruiting

A Multi-Institution Study of TGFβ Imprinted, Ex Vivo Expanded Universal Donor NK Cell Infusions as Adoptive Immunotherapy in Combination With Gemcitabine and Docetaxel in Patients With Relapsed or Refractory Pediatric Bone and Soft Tissue (TINKS)

Pediatric Sarcoma, Refractory | Pediatric Sarcoma, Relapsed

United States
Salarius Pharmaceuticals, LLC
National Pediatric Cancer Foundation

Active, not recruiting

Clinical Trial of SP-2577 (Seclidemstat) in Patients With Relapsed or Refractory Ewing or Ewing-related Sarcomas

Ewing Sarcoma | Myxoid Liposarcoma | Fibromyxoid Tumor | Sarcoma,Soft Tissue | Desmoplastic Small Round Cell Tumor | Angiomatoid Fibrous Histiocytoma | Extraskeletal Myxoid Chondrosarcoma | Clear Cell Sarcoma | Primary Pulmonary Myxoid Sarcoma | Myoepithelial Tumor | Sclerosing Epithelioid Fibrosarcoma

United States
H. Lee Moffitt Cancer Center and Research Institute
National Pediatric Cancer Foundation

Recruiting

Evolutionary Therapy for Rhabdomyosarcoma

Rhabdomyosarcoma

United States
H. Lee Moffitt Cancer Center and Research Institute
National Pediatric Cancer Foundation

Active, not recruiting

Nab-Paclitaxel and Gemcitabine for Recurrent/Refractory Sarcoma

Soft Tissue Sarcoma | Osteosarcoma | Ewing Sarcoma | Rhabdomyosarcoma

United States
H. Lee Moffitt Cancer Center and Research Institute
Pediatric Cancer Foundation

Completed

Vincristine, Dexamethasone, Doxorubicin, and PEG-asparaginase (VPLD) and Metformin for Relapsed Childhood Acute Lymphoblastic Leukemia (ALL)

Acute Lymphoblastic Leukemia

United States
H. Lee Moffitt Cancer Center and Research Institute
Pediatric Cancer Foundation

Completed

Metformin in Children With Relapsed or Refractory Solid Tumors

Solid Tumors | Primary Brain Tumors

United States
H. Lee Moffitt Cancer Center and Research Institute
Bayer; Pediatric Cancer Foundation

Completed

Sorafenib and Topotecan in Refractory/Recurrent Pediatric Malignancies

Solid Tumor

United States
National Center for Research Resources (NCRR)
Elizabeth Glaser Pediatric AIDS Foundation

Completed

The Metabolic Effects of Protease Inhibitors in HIV Infected Children

HIV Infections

United States
University of California, San Francisco
Novartis Pharmaceuticals; Pediatric Brain Tumor Foundation; The Lilabean Foundation...

Recruiting

Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021)

High Grade Glioma | Low-grade Glioma | Recurrent World Health Organization (WHO) Grade II Glioma

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Terminated

Palbociclib Isethionate in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors

Recurrent Childhood Medulloblastoma | Childhood Choroid Plexus Tumor | Childhood Ependymoblastoma | Childhood Grade III Meningioma | Childhood High-grade Cerebellar Astrocytoma | Childhood High-grade Cerebral Astrocytoma | Childhood Medulloepithelioma | Recurrent Childhood Anaplastic Astrocytoma | Recurrent... and other conditions

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Withdrawn

Biomarkers in Blood Samples From Young Patients With Newly Diagnosed Brain Tumors Undergoing Standard Radiation Therapy and Chemotherapy

Brain and Central Nervous System Tumors

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Terminated

Oncolytic HSV-1716 in Treating Younger Patients With Refractory or Recurrent High Grade Glioma That Can Be Removed By Surgery

Recurrent Childhood Anaplastic Astrocytoma | Recurrent Childhood Anaplastic Oligoastrocytoma | Recurrent Childhood Anaplastic Oligodendroglioma | Recurrent Childhood Giant Cell Glioblastoma | Recurrent Childhood Glioblastoma | Recurrent Childhood Gliomatosis Cerebri | Recurrent Childhood Gliosarcoma

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Withdrawn

Studying Cerebrospinal Fluid Proteins and Angiogenesis Proteins in Young Patients With Newly Diagnosed Central Nervous System Tumors

Brain and Central Nervous System Tumors

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Completed

Genetic Study of Newly Diagnosed Central Nervous System Tumors in Young Children

Central Nervous System Embryonal Neoplasm

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Completed

VNP40101M in Treating Young Patients With Recurrent, Progressive, or Refractory Primary Brain Tumors

Brain and Central Nervous System Tumors

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Withdrawn

Immunotoxin Therapy in Treating Children With Recurrent Malignant Gliomas

Brain and Central Nervous System Tumors
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Terminated

SU5416 in Treating Children With Recurrent or Progressive Brain Tumors

Brain and Central Nervous System Tumors

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Completed

Ribociclib and Everolimus in Treating Children With Recurrent or Refractory Malignant Brain Tumors

Malignant Glioma | Recurrent Childhood Ependymoma | Recurrent Medulloblastoma | Recurrent Diffuse Intrinsic Pontine Glioma | Recurrent Atypical Teratoid/Rhabdoid Tumor | Refractory Diffuse Intrinsic Pontine Glioma | CNS Embryonal Tumor, Not Otherwise Specified

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Completed

p28 in Treating Younger Patients With Recurrent or Progressive Central Nervous System Tumors

Glioblastoma | Gliosarcoma | Medulloblastoma | Anaplastic Astrocytoma | Choroid Plexus Neoplasms | Anaplastic Oligodendroglioma | Giant Cell Glioblastoma | Neuroectodermal Tumor, Primitive | Brainstem Tumors | Teratoid Tumor, Atypical

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Completed

Capecitabine and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Nonmetastatic Brain Stem Glioma or High-Grade Glioma

Brain and Central Nervous System Tumors

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Terminated

MK0752 in Treating Young Patients With Recurrent or Refractory CNS Cancer

Brain and Central Nervous System Tumors

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Terminated

Topotecan in Treating Young Patients With Neoplastic Meningitis Due to Leukemia, Lymphoma, or Solid Tumors

Lymphoma | Unspecified Childhood Solid Tumor, Protocol Specific | Leukemia | Brain and Central Nervous System Tumors | Carcinoma of Unknown Primary

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Completed

Oxaliplatin in Treating Children With Recurrent or Refractory Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Atypical Teratoid Rhabdoid Tumor

Brain and Central Nervous System Tumors

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Completed

SCH 66336 in Treating Children With Recurrent or Progressive Brain Tumors

Brain and Central Nervous System Tumors

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Completed

Busulfan in Treating Children and Adolescents With Refractory CNS Cancer

Sarcoma | Lymphoma | Leukemia | Brain and Central Nervous System Tumors | Metastatic Cancer | Retinoblastoma | Childhood Germ Cell Tumor

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Completed

Trial of Panobinostat in Children With Diffuse Intrinsic Pontine Glioma (PBTC-047)

Glioma

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Terminated

Peginterferon Alfa-2b in Younger Patients With Craniopharyngioma That is Recurrent or Cannot Be Removed By Surgery

Childhood Craniopharyngioma

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Terminated

Imetelstat Sodium in Treating Younger Patients With Recurrent or Refractory Brain Tumors

Glioblastoma | Gliosarcoma | Ependymoma | Anaplastic Astrocytoma | Oligodendroglioma | Anaplastic Ependymoma | Giant Cell Glioblastoma | Astrocytoma, Grade II | Brainstem Tumors

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Completed

Enzastaurin in Treating Young Patients With Refractory Primary CNS Tumors

Brain and Central Nervous System Tumors | Neuroblastoma

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Terminated

Genetic Study of Brain Tumors in Young Children

Central Nervous System Tumor, Pediatric

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Terminated

TP-38 Toxin in Treating Young Patients With Recurrent or Progressive Supratentorial High-Grade Glioma

Brain and Central Nervous System Tumors

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Terminated

Carmustine Implants and O(6)-Benzylguanine in Treating Children With Recurrent Malignant Glioma

Brain and Central Nervous System Tumors

United States
National Cancer Institute (NCI)
Children's Cancer Group; Pediatric Oncology Group

Completed

Health-Related Outcomes in Patients Who Were Previously Treated for Rhabdomyosarcoma

Sarcoma | Long-term Effects Secondary to Cancer Therapy in Children
University of California, Los Angeles
Rally Foundation for Childhood Cancer Research; Bear Necessities Pediatric...

Completed

Adolescent Cancer Telemedicine for Pain Management

Cancer

United States
University of Florida
National Cancer Institute (NCI); National Institutes of Health (NIH); National... and other collaborators

Active, not recruiting

Adoptive Cellular Therapy in Pediatric Patients With High-grade Gliomas (ACTION)

High Grade Glioma | Malignant Glioma

United States
American Academy of Pediatrics
National Cancer Institute (NCI)

Completed

Adolescent Smoking Cessation in Pediatric Primary Care (Smokebusters)

Tobacco Cessation | Media Use

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Lance Armstrong Foundation

Active, not recruiting

Depression Treatment and Screening in Ovarian Cancer Patients

Ovarian Cancer | Fallopian Tube Cancer | Peritoneal Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Foundation for Women's Cancers

Recruiting

Lifestyle Intervention for the Reduction of Breast Cancer Risk in Normal Weight Women

Breast Carcinoma

United States
University of Helsinki
Royal Children's Hospital; Murdoch Childrens Research Institute; University of... and other collaborators

Active, not recruiting

Healthcare Transition of Adolescents With Chronic Health Conditions

Liver Diseases | Kidney Diseases | Diabetes | Rheumatic Diseases | Inflammatory Bowel Diseases | Neurologic Disorder | Congenital Heart Disease | Transition

Australia, Finland
Karen D. Wright, MD
National Cancer Institute (NCI); Pacific Pediatric Neuro-Oncology Consortium; Day One Biopharmaceuticals, Inc... and other collaborators

Active, not recruiting

DAY101 In Gliomas and Other Tumors

Low-grade Glioma

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI); PTC Therapeutics

Completed

PTC299 in Treating Young Patients With Refractory or Recurrent Primary Central Nervous System Tumors

Brain and Central Nervous System Tumors

United States
Children's Oncology Group
National Cancer Institute (NCI); Pediatric Oncology Group

Completed

Radiation Therapy Plus Combination Chemotherapy in Treating Children With Medulloblastoma

Brain Tumors | Central Nervous System Tumors

United States, Puerto Rico, Switzerland, Australia, Canada
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI); Memorial Sloan Kettering Cancer Center; Y-mAbs...

Active, not recruiting

131I-Omburtamab, in Recurrent Medulloblastoma and Ependymoma

Recurrent Ependymoma | Recurrent Medulloblastoma

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); Conquer Cancer Foundation

Completed

Resistance Training Program and Cardiovascular Exercise in Increasing Muscle Mass in Adolescent and Young Adult Stem Cell Transplant Survivors

Malignant Neoplasm

United States
M.D. Anderson Cancer Center
National Alopecia Areata Foundation

Active, not recruiting

Alopecia Areata Registry (NAAR)

Alopecia Areata | Alopecia Totalis | Alopecia Universalis | Autoimmune Hair Loss | Alopecia Partialis

United States
Children's Oncology Group
National Cancer Institute (NCI); Pediatric Brain Tumor Consortium

Active, not recruiting

Pilot Study to Enable Electronic Laboratory Data Transfer From Participating Institutions to MediData/RAVE

Accurate and Complete Data Acquisition for Clinical Trials

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); Livestrong Foundation

Completed

Survivorship Care in Reducing Symptoms in Young Adult Cancer Survivors

Depression | Soft Tissue Sarcoma | Pain | Lymphoma | Leukemia | Fatigue | Sleep Disorder | Breast Carcinoma | Cancer Survivor | Malignant Female Reproductive System Neoplasm | Malignant Digestive System Neoplasm | Malignant Male Reproductive System Neoplasm | Malignant Bone Neoplasm

United States
Dana-Farber Cancer Institute
Stahl Family Charitable Foundation; The Childhood Brain Tumor Foundation; Pedals...

Recruiting

High-Intensity Interval Exercise in Young Adult Survivors of Pediatric Brain Tumors: A Pilot Feasibility Study (HYPE)

Pediatric Brain Tumor

United States
Geriatric Education and Research Institute
National Healthcare Group, Singapore; Tsao Foundation

Completed

The COPACC Study: Utilization, Health and Economic Evaluation of a Community-Based Primary Care Geriatric Hub at Whampoa

Quality of Life | Health Services | Delivery of Health Care | Costs and Cost Analysis

Singapore
Nordic Society for Pediatric Hematology and Oncology
Danish Child Cancer Foundation; Medac, Hamburg, Germany

Unknown

Poly(Ethylene Glycol)(PEG)-Asparaginase During Two Treatment Courses

Acute Lymphoblastic Leukemia

Denmark

Clinical Trials Sponsored by National Pediatric Cancer Foundation

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Gabon

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations