Clinical Trials Sponsored by Newcastle-upon-Tyne Hospitals NHS Trust

Total 155 results

Isotech Ltd
Newcastle-upon-Tyne Hospitals NHS Trust

Recruiting

A Novel Device for the Treatment of Postural Hypotension - a Signal of Effectiveness Study.

Orthostatic Hypotension

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
Jain Foundation

Active, not recruiting

Clinical Outcome Study for Dysferlinopathy (Jain COS)

Dysferlinopathy | LGMD2B Now Classified as LGMDR2 | Miyoshi Myopathy

Korea, Republic of, Chile, Spain, United States, Denmark, France, Italy, Japan, United Kingdom
Biosignatures Limited
Newcastle-upon-Tyne Hospitals NHS Trust

Completed

Cystoscopic Imaging Collection and Enhancement pROject (CICERO)

Urinary Bladder Neoplasms
Northumbria University
Newcastle-upon-Tyne Hospitals NHS Trust

Recruiting

Protein Intake in Patients With Coronary Heart Disease

Sarcopenia | Coronary Heart Disease | Low Protein Intake

United Kingdom
Northumbria University
Newcastle-upon-Tyne Hospitals NHS Trust

Completed

Physical Activity Promotion Added to Standard Care Pulmonary Rehabilitation and Cognitive Behavioural Therapy

Chronic Obstructive Pulmonary Disease

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
Northumbria University

Unknown

Preterm Lung Function and Exercise Response Measured by OEP

Premature Birth

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
DePuy Orthopaedics

Completed

Predicting Poor Outcomes After Primary Knee Arthroplasty

Osteoarthritis, Knee
Northumbria Healthcare NHS Foundation Trust
Newcastle-upon-Tyne Hospitals NHS Trust

Recruiting

Influence of Reliance on Historical Blood Eosinophil Counts on ICS Prescribing by GOLD 2019 Thresholds in COPD (BECCOPD)

Chronic Obstructive Pulmonary Disease

United Kingdom
Newcastle University
Newcastle-upon-Tyne Hospitals NHS Trust; Unilever SEAC

Completed

Metagenome Resilience in Experimental Gingivitis

Gingivitis | Oral Disease

United Kingdom
University Hospital, Montpellier
Newcastle-upon-Tyne Hospitals NHS Trust

Recruiting

Clinical Validation of a Mobility Monitor to Measure and Predict Health Outcomes (MOBILISE-D)

Hip Fractures

France
South Tees Hospitals NHS Foundation Trust
Newcastle-upon-Tyne Hospitals NHS Trust

Not yet recruiting

Thrombogenicity of Lipoprotein A: Laboratory Study Defining the Prothrombotic Effects of Lipoprotein A

Cardiac Disease | Cardiovascular Disease and Lipid Disorders

United Kingdom
Newcastle University
Newcastle-upon-Tyne Hospitals NHS Trust; Cumbria, Northumberland Tyne and Wear...

Completed

Reducing Uncertainty Distress in Long Term Health Conditions

Rheumatic Diseases

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
Cancer Research UK

Completed

A Feasibility Study for a Multicentre Randomised Controlled Trial to Compare Surgery With Needle Ablation Techniques in People With Small Renal Masses (4cm) (CONSERVE)

Renal Cancer

United Kingdom
Newcastle University
Newcastle-upon-Tyne Hospitals NHS Trust; Arthritis Research UK

Completed

Autologous Tolerogenic Dendritic Cells for Rheumatoid Arthritis (AutoDECRA) (AutoDECRA)

Rheumatoid Arthritis

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
Medical Research Council; Newcastle University

Completed

Does GM-CSF Restore Neutrophil Phagocytosis in Critical Illness? (GMCSF)

Sepsis | Critical Illness | Immuno-suppression

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
University of Newcastle Upon-Tyne; North Tyneside Primary Care Trust; Northumberland...

Completed

Pilot: Group Therapy for Children Who Stammer

Stammering

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
Newcastle University; British Heart Foundation

Active, not recruiting

The British Heart Foundation SENIOR-RITA Trial (SENIOR-RITA)

NSTEMI - Non-ST Segment Elevation MI

United Kingdom
Newcastle University
Sanofi; Medtronic; Newcastle-upon-Tyne Hospitals NHS Trust; Newcastle Primary Care...

Completed

Prevention of Severe Hypoglycemia in Type 1 Diabetes

Type 1 Diabetes Mellitus

United Kingdom
Resolve Therapeutics
Newcastle-upon-Tyne Hospitals NHS Trust; University Hospital Birmingham

Completed

A Study of RSLV-132 in Subjects With Primary Sjogren's Syndrome (RSLV-132)

Sjogren's Syndrome

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
Newcastle University; DSM Nutritional Products, Inc.

Completed

Effect of SNPs in the BCMO1 Enzyme (BETASNP2)

Vitamin A Deficiency | Beta-carotene Bioavailability

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
The Urology Foundation, UK

Unknown

Hyaluronate for the Treatment and Prevention of Recurrent Urinary Tract Infection in Women Suffering Atrophic Vaginitis (HATPIN)

Urinary Tract Infections | Atrophic Vaginitis

United Kingdom
South Tees Hospitals NHS Foundation Trust
Newcastle University; Newcastle-upon-Tyne Hospitals NHS Trust; University of...

Completed

PROACT: Can we Prevent Chemotherapy-related Heart Damage in Patients With Breast Cancer and Lymphoma? (PROACT)

Breast Cancer | Non Hodgkin Lymphoma

United Kingdom
Cardiff University
University of Birmingham; Newcastle-upon-Tyne Hospitals NHS Trust

Recruiting

Primary Care Management of Lower Urinary Tract Symptoms in Men (PriMUS)

Lower Urinary Tract Symptoms

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...
Newcastle-upon-Tyne Hospitals NHS Trust

Completed

Treosulfan Pharmacokinetics in Children Undergoing Allogeneic HSCT (TreoPK)

Allogeneic Haematopoietic Stem Cell Transplantation

United Kingdom
Northumbria University
Newcastle-upon-Tyne Hospitals NHS Trust; Gateshead Health NHS Foundation Trust and other collaborators

Active, not recruiting

CIPN in Early Stage Breast Cancer Patients

Breast Cancer | Chemotherapy-induced Peripheral Neuropathy

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
Biotechnology and Biological Sciences Research Council

Completed

Bioactive Dietary Fibres and Obesity (FIBREFOODS)

Obesity
Newcastle-upon-Tyne Hospitals NHS Trust
University of Nottingham; Quadram Institute Bioscience

Completed

Where is the Initial Site of Biotransformation of Folates in Humans? (FOLTIPS)

Healthy

United Kingdom
Liverpool Heart and Chest Hospital NHS Foundation...
Newcastle-upon-Tyne Hospitals NHS Trust; Imperial College Healthcare NHS Trust

Not yet recruiting

The RIPPLE AT-PLUS Study

Atrial Tachycardia

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
Newcastle University; National Institute for Health Research, United Kingdom

Completed

Ciclosporin to Reduce Reperfusion Injury in Primary PCI (CAPRI)

Myocardial Reperfusion Injury

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
Northumbria Healthcare NHS Foundation Trust; North East Ambulance Service NHS...

Completed

Paramedic Initiated Lisinopril For Acute Stroke Treatment (PIL-FAST)

Stroke

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
National Institute for Health Research, United Kingdom

Completed

A Novel Home-based Physical Activity Intervention for Stable Chronic Heart Failure Patients (PAHF)

Heart Failure, Systolic
Newcastle-upon-Tyne Hospitals NHS Trust
National Institute for Health Research, United Kingdom

Completed

Study of Optimal Replacement of Thyroxine in the Elderly (SORTED)

Hypothyroidism

United Kingdom
University of Dundee
Newcastle-upon-Tyne Hospitals NHS Trust; Oxford University Hospitals NHS Trust and other collaborators

Completed

DIabetes REsearCh on Patient sTratification (DIRECT): GLP-1R Agonists (DIRECTGLP)

Diabetes

United Kingdom
Newcastle University
Bristol-Myers Squibb; Institute of Cancer Research, United Kingdom; Newcastle-upon-Tyne... and other collaborators

Completed

Comparison of Imatinib Versus Dasatinib in Patients With Newly-diagnosed Chronic Phase Chronic Myeloid Leukaemia (SPIRIT2)

Myeloid Leukemia, Chronic, Chronic Phase

United Kingdom
North Tees and Hartlepool NHS Foundation Trust
Newcastle-upon-Tyne Hospitals NHS Trust; Gateshead Health NHS Foundation Trust and other collaborators

Unknown

Investigating the Use of Drains and (Internal) Quilting Sutures on Seroma Formation Following Mastectomy

Breast Cancer

United Kingdom
Gateshead Health NHS Foundation Trust
Newcastle-upon-Tyne Hospitals NHS Trust; National Institute for Health Research...

Unknown

Vascular Augmentation of Late-life Unremitted Depression (VALUeD) (VALUeD)

Depression

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
National Institute for Health Research, United Kingdom; Alder Hey Children's...

Recruiting

Airway Intervention Registry (AIR): Recurrent Respiratory Papillomatosis (RRP) (AIR:RRP)

Human Papilloma Virus | Recurrent Respiratory Papillomatosis

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
Cardiff and Vale University Health Board; Royal Devon and Exeter NHS Foundation...

Completed

Post-Radioiodine Graves' Management: The PRAGMA-Study (PRAGMA)

Graves' Disease

United Kingdom
Newcastle University
Northumberland, Tyne and Wear NHS Foundation Trust

Completed

Cognitive Therapy for Distressing Visual Hallucinations: A Pilot Study

Psychotic Disorders | Visual Hallucinations

United Kingdom
Imperial College Healthcare NHS Trust
Nottingham University Hospitals NHS Trust; Barts & The London NHS Trust; Hospital... and other collaborators

Completed

Ripple Mapping Guided Ablation of Ischaemic Ventricular Tachycardia. (RIPPLE-VT)

Ischemic Heart Disease | Ventricular Tachycardia

United Kingdom
Northumbria Healthcare NHS Foundation Trust
Newcastle-upon-Tyne Hospitals NHS Trust; National Institute for Health Research... and other collaborators

Completed

Mortality and Symptom Burden Post Hospitalisation With COPD (MoSHCOPD)

Pulmonary Disease, Chronic Obstructive | Emphysema | Chronic Bronchitis | Pulmonary Disease, Obstructive | Chronic Bronchitis With Airways Obstruction | Chronic Bronchitis With Acute Exacerbation

United Kingdom
University College, London
University College London Hospitals; The Leeds Teaching Hospitals NHS Trust; Nottingham... and other collaborators

Unknown

COVID-19 Hyperinflammation Syndrome (COV-HI): Protocol for a Rapidly Executed Cohort Study (COV-HI)

COVID-19 | COV-HI | COVID-19 (COV) Hyperinflammatory (HI) Syndrome

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
Newcastle University; National Institute for Health Research, United Kingdom; Department of Health, United Kingdom

Completed

B-Cell Depleting Therapy (Rituximab) as a Treatment for Fatigue in Primary Biliary Cirrhosis (RITPBC)

Fatigue | Primary Biliary Cirrhosis

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
Cambridge University Hospitals NHS Foundation Trust; University of Southampton and other collaborators

Completed

Antibiotic Prophylaxis for Clean Intermittent Catheterisation (AnTIC)

Urinary Tract Infections, Recurrent

United Kingdom
Royal Devon and Exeter NHS Foundation Trust
King's College London; King's College Hospital NHS Trust; Newcastle University; Newcastle-upon-Tyne Hospitals NHS Trust and other collaborators

Completed

PROMASTER - PROspective Cohort MRC ABPI STratification and Extreme Response Mechanism in Diabetes (PROMASTER)

Diabetes

United Kingdom
University of Southampton
University of Leeds; Newcastle-upon-Tyne Hospitals NHS Trust; National Institute... and other collaborators

Not yet recruiting

Promoting Increased Physical Activity in Hospitalised Older Adults (PIVOT)

Hospital-associated Deconditioning
Newcastle-upon-Tyne Hospitals NHS Trust
King's College London; University College, London; Newcastle University; University... and other collaborators

Terminated

Multi-centre UK Study of the Acetylcholinesterase Inhibitor Donepezil in Early Dementia Associated With Parkinson's Disease (MUSTARDD-PD)

Parkinson's Disease

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; University of Cambridge; University of Newcastle Upon-Tyne and other collaborators

Recruiting

Pulmonary Hypertension: Intensification and Personalisation of Combination Rx (PHoenix)

Pulmonary Arterial Hypertension

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; University of Liverpool; University of Newcastle Upon-Tyne and other collaborators

Recruiting

Ii-HANC Improving Incurable Head and Neck Cancer Healthcare Experiences

Head and Neck Cancer

United Kingdom
Royal Marsden NHS Foundation Trust
University College, London; The Leeds Teaching Hospitals NHS Trust; Belfast Health... and other collaborators

Unknown

Targeted Radiotherapy in Androgen-suppressed Prostate Cancer Patients. (TRAP)

Prostate Cancer | Metastasis | Toxicity Due to Radiotherapy | Circulating Tumour DNA

United Kingdom

Clinical Trials Sponsored by Newcastle-upon-Tyne Hospitals NHS Trust

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