Clinical Trials Sponsored by NicOx Inc.

Total 35496 results

Nicox Ophthalmics, Inc.

Completed

Study Evaluating the Safety and Efficacy of NCX 4251 Ophthalmic Suspension for the Treatment of Blepharitis (Mississippi)

Blepharitis

United States
Nicox Ophthalmics, Inc.

Completed

Phase 2 Dose-Response Study Evaluating the Safety and Efficacy of NCX 470 vs Latanoprost in Subjects With Open-Angle Glaucoma or Ocular Hypertension

Glaucoma, Open-Angle | Hypertension, Ocular

United States
Nicox Ophthalmics, Inc.

Completed

Study Evaluating the Safety and Tolerability of NCX 4251 for the Treatment of Acute Exacerbations of Blepharitis

Blepharitis

United States
Nicox Ophthalmics, Inc.

Completed

Phase 3 Trial of NCX 470 vs. Latanoprost in Subjects With Open-Angle Glaucoma or Ocular Hypertension (Mont Blanc)

Ocular Hypertension | Open Angle Glaucoma

United States
Nicox Ophthalmics, Inc.

Recruiting

Aqueous Humor Dynamics of NCX 470 Ophthalmic Solution (Whistler)

Open Angle Glaucoma

United States
Nicox Ophthalmics, Inc.

Recruiting

MRCT Evaluating NCX 470 vs. Latanoprost in Subjects With Open-Angle Glaucoma or Ocular Hypertension (Denali)

Ocular Hypertension | Open Angle Glaucoma

United States, China
NicOx

Completed

ADenoVirus Initiative Study in Epidemiology in Italy

Viral Conjunctivitis

Italy
NicOx

Completed

Efficacy and Safety Study of Naproxcinod in Subjects With Osteoarthritis of the Knee

Osteoarthritis

United States
NicOx

Completed

To Assess the Effect of Naproxcinod Versus Naproxen and Ibuprofen on Arterial Blood Pressure in Osteoarthritis Patients With Controlled Essential Hypertension (HCT3012-X-112)

Hypertension | Osteoarthritis

United States
Nicox Ophthalmics, Inc.
ORA, Inc.

Completed

A Multi-Center, Vehicle-Controlled, Parallel-Group Study Evaluating the Safety of AC-170 Ophthalmic Solution

Healthy Subjects

United States
NicOx

Completed

ADenoVirus Initiative Study in Epidemiology in Germany

Viral Conjunctivitis

Germany
NicOx

Completed

A Study to Assess the Effects of Naproxcinod and Naproxen on Blood Pressure Measurements in Osteoarthritis Patients With Controlled High Blood Pressure (HCT3012-X-111)

Hypertension | Osteoarthritis

United States
NicOx

Completed

A Phase 1 Study to Compare the PK and Safety of Naproxcinod in Hepatic Impaired Patients and Matching Healthy Subjects

Liver Disease

United States
NicOx

Completed

Efficacy and Safety Study of Naproxcinod in Subjects With Osteoarthritis of the Hip

Osteoarthritis | Osteoarthritis, Hip

United States, Canada
NicOx

Completed

A Pharmacokinetics and Safety Study of Naproxcinod in Subjects With Impaired Renal Function (HCT3012-X-106)

Renal Failure

United States
NicOx

Completed

ADenoVirus Initiative Study in Epidemiology in Spain

Viral Conjunctivitis

Spain
NicOx

Completed

ADenoVirus Initiative Study in Epidemiology in UK

Viral Conjunctivitis

United Kingdom
NicOx

Completed

ADenoVirus Initiative Study in Epidemiology in France

Viral Conjunctivitis

France
NicOx

Completed

Pharmacokinetics Study: Determination of Naproxcinod and Its Metabolites After Oral Administration in Male

Pharmacokinetics
NicOx

Completed

Effect of Repeated Dosing of Naproxcinod on Renal Hemodynamic and on Sodium Balance in Healthy Volunteers Before and After a Single Dose of Furosemide

Renal Hemodynamics
NicOx

Completed

Analgesic Efficacy and Safety Study of Naproxcinod in Subjects With Osteoarthritis of the Knee

Osteoarthritis
Bausch & Lomb Incorporated
NicOx Inc.

Completed

Dose-Finding Study Comparing the Safety and Efficacy of Latanoprost to a Novel Treatment for Glaucoma

Primary Open Angle Glaucoma | Ocular Hypertension | Pigmentary Glaucoma | Pseudoexfoliative Glaucoma

United States
Viz.ai, Inc.
Nico Corporation

Enrolling by invitation

AI ENRICH - AI Detection of ICH

Intracerebral Hemorrhage

United States
NicOx Research Institute S.r.l.

Completed

Effect of NCX4016 on Walking Distance in Patients With Peripheral Arterial Occlusive Disease (PAOD)

Intermittent Claudication

Italy
NicOx
Theradis pharma; Iris Pharma

Withdrawn

Efficacy and Safety of Iota-Carrageenan Eye Drops (NCX-4240) (Goldeneye)

Adenoviral Conjunctivitis

Spain
Nico Corporation
Emory University

Completed

ENRICH: Early MiNimally-invasive Removal of IntraCerebral Hemorrhage (ICH) (ENRICH)

Cerebral Hemorrhage | Intracerebral Hemorrhage | Intracerebral Haemorrhage

United States
University of Maryland, Baltimore
Nico Corporation

Recruiting

Safety and Suitability of Supplementing Early MIP Surgery (MIPS) of ICH With Pioglitazone (ENRICHPLUS)

Intracerebral Haemorrhage, Intraventricular

United States
Baptist Health South Florida
Nico Corporation; Miami Cancer Institute

Not yet recruiting

Improving Understanding of Glioblastoma Through Preservation of Biologically Active Brain Tissue

Glioblastoma | Glioblastoma Multiforme | Gliosarcoma

United States
Region Stockholm
Karolinska Institutet; Uppsala University; Universidade do Porto; Niox Group Plc

Enrolling by invitation

Cluster-Randomized Asthma FeNO Trial (CRAFT)

Asthma

Sweden
IND Diagnostic Inc.

Unknown

Evaluation of the IND One Step Strep A Rapid Test vs. Culture

Strep Throat

United States
University Hospital, Essen
Nico Reinsch M. D.; Till Neumann Prof. M. D.

Completed

A Prospective Observational Trial to Determine Cardiovascular Diseases in HIV-infected Patients (HIV-HEART10)

Myocardial Infarction | Heart Failure | Aging | Coronary Heart Disease | HIV-infection | HIV-encephalopathy

Germany
University of California, San Francisco
San Francisco State University; NICOS Chinese Health Coalition

Completed

Lay Health Workers and Colorectal Cancer Screening Among Chinese Americans

Colorectal Neoplasms

United States
University Hospital, Montpellier
Luc Nicon, Education Specialist, Founder of "Tipi", a non-profit French association

Completed

Treating Phobia by a New Emotional Regulation Method (Tipi) (RE)

Phobic Fear

France
UNC Lineberger Comprehensive Cancer Center
Genentech, Inc.; Oncoceutics, Inc.

Recruiting

ONC201 and Atezolizumab in Obesity-Driven Endometrial Cancer

Metastasis | Endometrial Cancer

United States
NC Medial Research Inc

Recruiting

A Study of NCS-01 in Patients With Acute Ischemic Stroke

Ischemic Stroke

United States
IC-IT Sciences Inc.

Unknown

Comparison of the Natural Frequencies Technology Sleep Patches to Sham Patches During Sleep in the Home Environment

Sleep Disturbance

United States
Zhengzhou Gensciences Inc
Haimen Gensciences lnc

Completed

An Open Label Study to Determine the Safety and Efficacy of Recombinant Human Coagulation Factor VIII-Fc Fusion Protein for Injection in Adolescent and Adult Patients With Hemophilia A.

Hemophilia A

China
Zhengzhou Gensciences Inc
Jiangsu Gensciences lnc.

Completed

Phase III Expansion Trial for Determining the Safety and Efficacy of Recombinant Human Coagulation Factor VIII-Fc Fusion Protein for Injection in Adolescent and Adult Patients With Hemophilia A (RH-107-III02)

Hemophilia A

China
UNC Lineberger Comprehensive Cancer Center
Seagen Inc.

Completed

Induction Chemo w/ABVD Followed by Brentuximab Vedotin Consolidation in Newly Diagnosed, Non-Bulky Stage I/II Hodgkin Lymphoma

Hodgkin Lymphoma, Adult

United States
UNC Lineberger Comprehensive Cancer Center
Genentech, Inc.

Terminated

Efalizumab in Treating Patients With Graft-Versus-Host Disease of the Skin That Did Not Respond to Previous Steroids (NRR)

Graft Versus Host Disease

United States
UNC Lineberger Comprehensive Cancer Center
Veracyte, Inc.

Recruiting

Harnessing Analysis RNA Expression and Molecular Subtype to Optimize Novel TherapY MBCA (HARMONY)

Breast Cancer

United States
UNC Lineberger Comprehensive Cancer Center
Seagen Inc.

Active, not recruiting

BV-CHEP Chemotherapy for Adult T-cell Leukemia or Lymphoma

Lymphoma | Lymphatic Diseases | Adult T-Cell Leukemia/Lymphoma

United States
IGC Pharma LLC

Completed

Study of IGC-AD1 in Subjects With Dementia Due to Alzheimer's Disease

Dementia of Alzheimer Type

Puerto Rico
UNC Lineberger Comprehensive Cancer Center
Genentech, Inc.

Completed

Cancer Patients' Performance Status Assessed Using Cardiopulmonary Exercise Testing and Wearable Data Generation

Hematologic Malignancies | Malignant Solid Tumor

United States
IGC Pharma LLC

Recruiting

IGC-AD1 Trial on Agitation in Dementia Due to Alzheimer's (IGC-AD1-P2)

Aggression | Depression | Anxiety | Alzheimer Disease | Memory Impairment | Agitated; State, Acute Reaction to Stress | Agitation,Psychomotor | Care Giving Burden | NPS | Aggressive Outburst

United States, Canada, Puerto Rico
UNC Lineberger Comprehensive Cancer Center
Genentech, Inc.

Recruiting

Polatuzumab Vedotin With R-GDP in Relapsed/Refractory Diffuse Large B-cell Lymphoma

Diffuse Large B-cell Lymphoma

United States
Novan, Inc.
Synteract, Inc.; Therapeutics, Inc.

Completed

A Phase 3 Molluscum Contagiosum Efficacy and Safety Study (B-SIMPLE4)

Molluscum Contagiosum

United States
OBELAB, Inc.
Helptrial Inc.

Not yet recruiting

Evaluation of rSO2 Between Frontal Lesion Area and Normal Area of Brain by NIRSITX Using NIRS in Acute Ischemic Stroke Patients.

Acute Ischemic Stroke Patients

Korea, Republic of
Athersys, Inc
Medpace, Inc.

Recruiting

MultiStem® Administration for Stroke Treatment and Enhanced Recovery Study (MASTERS-2)

Ischemic Stroke

United States, Taiwan
89bio, Inc.
ProSciento, Inc.

Completed

A Multiple Ascending Dose Study of Pegozafermin in Participants With Biopsy Confirmed Nonalcoholic Steatohepatitis (NASH) or Nonalcoholic Fatty Liver Disease (NAFLD) and at High Risk of NASH

NASH

United States, Puerto Rico

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