Clinical Trials Sponsored by Onconova Therapeutics, Inc

Total 2951 results

Palvella Therapeutics, Inc.

Active, not recruiting

VALO-2: Study Evaluating the Safety and Efficacy of PTX022 in the Treatment of Adults With Pachyonychia Congenita (VALO-2)

Pachyonychia Congenita

United States
Aimmune Therapeutics, Inc.

Completed

Oral Desensitization to Peanut in Peanut-Allergic Children and Adults Using Characterized Peanut Allergen OIT (ARC001)

Peanut Allergy

United States
Aimmune Therapeutics, Inc.

Completed

Oral Desensitization to Peanut in Peanut Allergic Children and Adults Using CPNA Peanut OIT Safety Follow-On Study

Peanut Allergy

United States
Magenta Therapeutics, Inc.

Completed

MGTA-456 in Patients With Inherited Metabolic Disorders Undergoing Hematopoietic Stem Cell Transplantation (HSCT)

Inherited Metabolic Disorders (IMD)

United States
Aimmune Therapeutics, Inc.

Completed

AR101 Real-World Open-Label Extension Study

Peanut Allergy

United States, Canada
Protagonist Therapeutics, Inc.

Terminated

Safety and Efficacy Study of PTG-100 in the Treatment of Moderate to Severe Ulcerative Colitis

Ulcerative Colitis

United States, Australia, Belgium, Bosnia and Herzegovina, Canada, Croatia, Czechia, Germany, Hungary, Korea, Republic of, Latvia, Netherlands, New Zealand, Poland, Russian Federation, Serbia, Ukraine
Amphivena Therapeutics, Inc.

Active, not recruiting

Study of AMV564 in Subjects With Advanced Solid Tumors

Locally Advanced or Metastatic Solid Tumors

United States
Amphivena Therapeutics, Inc.

Completed

A Phase 1 Study of AMV564 in Patients With Intermediate or High-Risk Myelodysplastic Syndromes

Myelodysplastic Syndrome (MDS)

United States
Mati Therapeutics Inc.

Completed

Safety/Efficacy of Nepafenac Punctal Plug Delivery System Compared to Placebo to Control Ocular Pain/Inflammation After Cataract

Pain | Inflammation

United States
Impact Therapeutics, Inc.

Completed

IMP4297 DDI (Drug-Drug Interaction)Trial in Healthy Male Volunteers

Solid Tumor

China
Arcturus Therapeutics, Inc.

Completed

Ascending Dose Study of Investigational SARS-CoV-2 Vaccine ARCT-021 in Healthy Adult Subjects

SARS-CoV-2

Singapore
miRagen Therapeutics, Inc.

Completed

Efficacy, Safety, and Tolerability of Remlarsen (MRG-201) Following Intradermal Injection in Subjects With a History of Keloids

Keloid

United States
Aimmune Therapeutics, Inc.

Completed

ARTEMIS Peanut Allergy In Children (ARTEMIS)

Peanut Allergy

United Kingdom, Italy, France, Germany, Ireland, Spain, Sweden
Odonate Therapeutics, Inc.

Terminated

Tesetaxel Plus Reduced Dose of Capecitabine vs. Capecitabine in HER2 Negative, HR Positive, LA/MBC (CONTESSA)

Breast Cancer

Korea, Republic of, United States, Spain, Canada, Singapore, Taiwan, Australia, Belgium, Thailand, Hungary, Germany, United Kingdom, France, Ukraine, Austria, Czechia, Italy, Poland, Russian Federation
Odonate Therapeutics, Inc.

Terminated

Tesetaxel Plus 3 Different PD-(L)1 Inhibitors in Patients With Triple-Negative MBC and Tesetaxel Monotherapy in Patients With HER2-Negative MBC (CONTESSA TRIO)

Breast Cancer

United States, Korea, Republic of, Singapore
Protagonist Therapeutics, Inc.

Completed

Safety Study for Beta Thalassemia Subjects on PTG-300 (TRANSCEND)

β-thalassemia | Ineffective Erythropoiesis

Malaysia, Thailand, United States, Greece, United Kingdom, Turkey, Lebanon, Tunisia
Clarus Therapeutics, Inc.

Completed

Open-label, Follow-up Study of Oral Testosterone Undecanoate in Hypogonadal Men

Male Hypogonadism

United States, Germany
CymaBay Therapeutics, Inc.

Completed

Study Investigating the Safety, Tolerability, and PK, PD, of CB-0406

Healthy Volunteers

Australia
Nanoscope Therapeutics Inc.

Completed

Dose-Escalation Study to Evaluate the Safety and Tolerability of Intravitreal vMCO-I in Patients With Advanced Retinitis Pigmentosa

Retinal Degeneration | Retinal Diseases | Retinitis Pigmentosa

India
Vyne Therapeutics Inc.

Completed

Study of the Efficacy, Safety and Tolerability of Serlopitant for the Treatment of Pruritus (Itch) With Plaque Psoriasis

Psoriasis | Pruritus

United States
Vyne Therapeutics Inc.

Terminated

Study of the Long Term Safety of Serlopitant for the Treatment of Pruritus (Itch)

Psoriasis | Pruritus | Atopic Dermatitis | Prurigo Nodularis

United States, Austria, Germany, Poland
Vyne Therapeutics Inc.

Completed

Study of the Efficacy, Safety, and Tolerability of Serlopitant for the Treatment of Chronic Pruritus of Unknown Origin

Pruritus

United States
BlackThorn Therapeutics, Inc.

Completed

BTRX-246040 Administered Once Daily to Patients With Major Depressive Disorder

Major Depressive Disorder

United States
Melinta Therapeutics, Inc.

Completed

Oritavancin Versus IV Vancomycin for the Treatment of Patients With Acute Bacterial Skin and Skin Structure Infection (SOLO II)

Abscess | Cellulitis | Wound Infection | Systemic Inflammation

United States
Tenax Therapeutics, Inc.

Active, not recruiting

Open-Label Rollover Study of Levosimendan in PH-HFpEF Patients

Heart Failure With Normal Ejection Fraction | Hypertension Pulmonary Secondary Heart Failure | Right Sided Heart Failure With Normal Ejection Fraction

United States
Viking Therapeutics, Inc.

Completed

Safety and Tolerability of VK2809 in Patients With Primary Hypercholesterolemia and Non-Alcoholic Fatty Liver Disease

NAFLD | Hyperlipidemia

United States
Viking Therapeutics, Inc.

Completed

Acute Hip Fracture Study in Patients 65 Years or Greater

Hip Fractures

Serbia, United States, Hungary, Romania
Anika Therapeutics, Inc.

Completed

MONOVISC for Shoulder Joint Pain Relief

Osteo Arthritis Shoulders

Poland, Czechia
Anika Therapeutics, Inc.

Completed

MONOVISC for Ankle Joint Pain Relief

Osteoarthritis Ankle

Poland, Czechia
GPCR Therapeutics, Inc.

Completed

PD and Safety of TG-0054 Combined With G-CSF in Multiple Myeloma, Non-Hodgkin Lymphoma and Hodgkin Disease Patients

Multiple Myeloma | Hodgkin Disease | Non-Hodgkin Lymphoma

United States
TScan Therapeutics, Inc.

Completed

Blood Collection Study From COVID-19 Convalescents Previously Hospitalized to Identify Immunogenic Viral Epitopes

Identify the Viral Epitopes of Memory CD8 T Cells From Individuals That Have Recovered From SARS-CoV-2 Infection | Determine Which SARS-CoV-2 Proteins Are Frequently Recognized by T Cells in Patients With Varying HLA Types

United States
Mirati Therapeutics Inc.

Terminated

Phase 1/2 Study of Mocetinostat and Durvalumab in Patients With Advanced Solid Tumors and NSCLC

Advanced Cancer

United States
Impact Therapeutics, Inc.

Completed

A Study of IMP4297 in Patients With Advanced Solid Tumors

Breast Cancer | Ovarian Cancer | Prostate Cancer | Advanced Solid Tumours

China
Emergo Therapeutics, Inc.

Completed

Norketotifen for the Treatment of Uncomplicated Influenza-like Illness

Influenza -Like Illness

United States
Magenta Therapeutics, Inc.

Terminated

A Follow-up Study in Patients With Inherited Metabolic Disorders (IMD) Who Underwent Hematopoietic Stem Cell Transplantation (HSCT) With MGTA-456 (IMD-002)

Inherited Metabolic Disorders (IMD)

United States
Vyne Therapeutics Inc.

Completed

A Study to Compare FCD105 Foam to Minocycline 3% Foam, Adapalene 0.3% Foam and Vehicle Foam.

Acne Vulgaris

United States
Hengrui Therapeutics, Inc.

Unknown

Phase I Study of Pyrotinib in Patients With HER2-positive Solid Tumors

Breast Cancer | Gastric Cancer | NSCLC | Solid Tumors

United States
Sarepta Therapeutics, Inc.

Completed

Study of Eteplirsen in DMD Patients (PROMOVI)

Duchenne Muscular Dystrophy (DMD)

United States
Lisata Therapeutics, Inc.

Withdrawn

CLBS119 for Repair of COVID-19 Induced Pulmonary Damage

Covid-19

United States
Clarus Therapeutics, Inc.

Completed

Pharmacokinetic Study to Determine Time to Steady-state

Male Hypogonadism | Secondary Hypogonadism | Primary Hypogonadism

United States
Aclaris Therapeutics, Inc.

Completed

A Study in Male and Female Subjects With Androgenetic Alopecia Treated With ATI-50002 Topical Solution

Androgenetic Alopecia

United States
Aclaris Therapeutics, Inc.

Completed

Study of A-101 for the Treatment of Seborrheic Keratosis

Seborrheic Keratosis

United States
Peloton Therapeutics, Inc.

Completed

A Food Effect Study in Healthy Volunteers With Belzutifan (PT2977, MK-6482) Tablets

Healthy

United States
Iconic Therapeutics, Inc.

Completed

Safety and Tolerability Study for Age-Related Macular Degeneration

Neovascular Age-Related Macular Degeneration

United States
Leap Therapeutics, Inc.

Completed

Phase 1 Open-label Study of TRX518 Monotherapy and TRX518 in Combination With Gemcitabine, Pembrolizumab, or Nivolumab

Solid Tumors

United States
GSNOR Therapeutics, Inc.

Unknown

A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Study to Evaluate the Efficacy and Safety of Cavosonstat Administered Twice Daily Compared With Placebo for 24 Weeks in Adult Subjects With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease (COPD)
Iconic Therapeutics, Inc.

Completed

Study Evaluating Intravitreal hI-con1™ in Patients With Choroidal Neovascularization Secondary to Age-related Macular Degeneration (EMERGE)

Age-related Macular Degeneration | Choroidal Neovascularization

United States
Aclaris Therapeutics, Inc.

Completed

ATI-501 Oral Suspension Compared to Placebo in Subjects With Alopecia Areata, Alopecia Universalis or Alopecia Totalis

Alopecia

United States
Galectin Therapeutics Inc.

Completed

An Open-Label, Phase 2a Study to Evaluate Safety and Efficacy of GR-MD-02 for Treatment of Psoriasis

Psoriasis

United States
Cara Therapeutics, Inc.

Completed

Study to Evaluate IV CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus

Uremic Pruritus

United States

Clinical Trials Sponsored by Onconova Therapeutics, Inc

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