Clinical Trials Sponsored by Optos, PLC

Total 11315 results

Optos, PLC

Terminated

P200TE Agreement and Precision Study

Glaucoma | Normal | Retina Disease

United States
Optos, PLC
Optos, Inc.

Unknown

Side-by-Side Comparison of P200TE and Spectral OCT/SLO on Diseased Eyes

Glaucoma | Retinal Disease

United States
Optos, PLC

Recruiting

P200TE and Predicate Agreement and Precision Study

Glaucoma | Normal | Retina Disease

United States
Optos, PLC

Active, not recruiting

P200TE US Reference Database Study

Normal Eyes

United States
Optos, PLC

Terminated

Data Collection With the P200TE and P200TxE

Retinal Disease

United States
Optos, PLC

Completed

Optic Disc Photograph Collection Study

Glaucoma | Normal | Retina Disease

United States
Optos, PLC

Completed

Study Comparing the P200TE and the P200TxE in Glaucoma Patients

Glaucoma

United States
Optos, PLC

Recruiting

Glaucoma Evaluation With the P200TE

Glaucoma

United States
Optos, PLC

Recruiting

P200TxE Diseased Eye Image Collection

Retinal Disease

United States
Optos, PLC

Completed

Navigated OCT Imaging With the P200TxE

Retinal Disease

United States
Optos, PLC

Completed

Image Collection of Normal Eyes for Development of an EU RDB

Healthy

United Kingdom
Optos, PLC

Completed

Optos P200TE Agreement and Precision Study

Glaucoma | Retinal Disease

United States
Genetic Disease Investigators
Optos, PLC

Completed

Vascular Fundus Changes in Patients With High Probability of Chronic Cerebrospinal Venous Insufficiency (CCSVI)

Multiple Sclerosis | Ehlers-Danlos Syndrome

United States
University of Edinburgh
NHS Lothian; Optos, PLC

Completed

REtinaL Imaging & Ambulatory BLood PrEssure (RELIABLE)

Hypertension | Blood Pressure

United Kingdom
Optos, PLC
Medical Center Ophthalmology Associates San Antonio, Texas

Unknown

ObseRvation of PeripHEral rEtinal Morphology in Normals (ORPHEE2)

Healthy

United States
Clinique Ortos

Completed

Application of Powdered Vancomycin in the Surgical Wound in Haiti

Surgical Site Infection

Haiti
Verily Life Sciences LLC
The Emmes Company, LLC; Optos, PLC; Google LLC.; Nikon Corporation

Completed

ARDA Software for the Detection of mtmDR

Diabetic Retinopathy

United States
Manchester University NHS Foundation Trust
Topcon Corporation; Optos, PLC

Withdrawn

Sub-threshold Photocoagulation of Diabetic Macular Oedema (MEM)

Diabetic Macular Oedema

United Kingdom
Optos, PLC
Johns Hopkins University; University of Southern California

Completed

Evaluation of the Precision of the Microperimetry Function of the Spectral OCT/SLO

Age-Related Macular Degeneration | Diabetic Retinopathy | Macular Edema | Retinal Vein Occlusion | Geographic Atrophy | Epiretinal Membrane | Macular Hole | Pattern Dystrophy of Macula | Central Serous Retinopathy

United States
Opto Eletronica S.A.

Unknown

Treatment of Patients With Neovascular AMD Using Indocyanine Green-Mediated Photothrombosis (i-MP).

Maculopathy, Age-Related

Brazil
Angle plc
MidLantic Urology, LLC

Terminated

Characterization of Circulating Tumor Cells (CTCs) in High Risk and Early Metastatic Prostate Cancer Patients Using Parsortix® System (CHARTER)

Prostate Cancer | Castration-resistant Prostate Cancer | Biochemically Recurrent Prostate Carcinoma | High Risk Prostate Carcinoma

United States
MedRegen LLC
Johns Hopkins University; ICON plc

Recruiting

MRG-001 as an Immunoregulatory and Regenerative Therapy for COVID-19 Patients

COVID-19 | ARDS, Human | Regeneration | Stem Cells

United States
Redx Pharma Plc
Merck Sharp & Dohme LLC

Completed

A Study to Assess RXC004 Efficacy in Advanced Solid Tumours After Progression on Standard of Care (SoC) Therapy (PORCUPINE2) (KEYNOTE-E86)

Advanced Solid Tumours

United Kingdom, Australia
4D pharma plc
Merck Sharp & Dohme LLC

Terminated

Live Biotherapeutic Product MRx0518 and Pembrolizumab Combination Study in Solid Tumors

Melanoma | Renal Cell Carcinoma | Solid Tumor | Non Small Cell Lung Cancer | Bladder Cancer | Oncology

United States
Insel Gruppe AG, University Hospital Bern
Stiftung OPOS; Fondation Bertarelli

Recruiting

Ocular Microbiome and Immune System in Dry Eyes

Dry Eye Disease

Switzerland
PTC Therapeutics
Axio Research. LLC

Completed

Safety and Efficacy Study of EPI-743 in Children With Leigh Syndrome

Leigh Syndrome

United States
Arthritis Northwest PLLC
Epigenesys LLC

Unknown

Identification of Epigenetic Biomarkers for Early Detection of Rheumatic Disease

Arthritis, Rheumatoid

United States
University of Zurich
Albert Bruppacher-Stiftung; Stiftung OPOS zugunsten von Wahrnehmungsbehinderten

Completed

Strabismus Measurements Using Automated 3D Video Oculography

Strabismus

Switzerland
Herantis Pharma Plc.
Renishaw plc.

Completed

Safety of CDNF by Brain Infusion in Patients With Parkinson's Disease. Extension to HP-CD-CL-2002 Clinical Study

Brain Diseases | Nervous System Diseases | Parkinson Disease | Movement Disorders | Neuro-Degenerative Disease

Sweden, Finland
Herantis Pharma Plc.
Renishaw plc.

Completed

Clinical Study to Test the Safety of CDNF by Brain Infusion in Patients With Parkinson's Disease

Brain Diseases | Nervous System Diseases | Parkinson Disease | Movement Disorders | Neurodegenerative Diseases

Sweden, Finland
Reckitt Benckiser LLC
Premier Research Group plc; Aptuit Inc.

Completed

Ibuprofen/Acetaminophen Versus Nurofen Plus® and Panadeine® Extra Dental Pain Study

Post-operative Pain

United States
Corium, Inc.
Premier Research Group plc; Almac; Prometrika, LLC

Active, not recruiting

An Efficacy and Safety Study w/ Azstarys® in Children With ADHD (KP415P01)

Attention Deficit/Hyperactivity Disorder

United States
NuCana plc

Recruiting

A Safety, Pharmacokinetic and Clinical Activity Study of NUC-7738 in Patients With Advanced Solid Tumours and Lymphoma

Lymphoma | Solid Tumor | Advanced Cancer

United Kingdom
NuCana plc

Terminated

Comparing NUC-1031 Plus Cisplatin to Gemcitabine Plus Cisplatin in Patients With Advanced Biliary Tract Cancer

Biliary Tract Cancer

Canada, United States, Spain, Hungary, Korea, Republic of, United Kingdom, Czechia, Germany, Russian Federation, Australia, France, Taiwan, Ukraine, Italy, Turkey
NuCana plc

Active, not recruiting

A Study of NUC-3373 in Combination With Other Agents in Patients With Colorectal Cancer

Colorectal Neoplasms | Colorectal Cancer | Colorectal Cancer Metastatic | Colorectal Adenocarcinoma | Neoplasm, Colorectal

United States, Spain, United Kingdom, Italy, Germany, France
Angle plc

Completed

Harvest of CTCs From MBC Patients Using the Parsortix™ PC1 System (HOMING)

Healthy Volunteers | Breast Cancer, Metastatic

United States
NuCana plc

Recruiting

NUC-3373 in Combination With Other Agents in Patients With Advanced Solid Tumours

Melanoma | Renal Cell Carcinoma | Gastric Cancer | Non Small Cell Lung Cancer | Metastatic Cancer | Triple Negative Breast Cancer | Advanced Solid Tumor | Advanced Cancer | Head and Neck Squamous Cell Carcinoma | Endometrial Carcinoma | Urothelial Carcinoma | Classical Hodgkin Lymphoma | Neoplasm Malignant | Pleural... and other conditions

United Kingdom
NuCana plc

Completed

A Safety, Pharmacokinetic and Efficacy Study of NUC-3373 in Combination With Standard Agents Used in Colorectal Cancer Treatment

Colorectal Neoplasms | Colorectal Cancer | Colorectal Tumors | Colorectal Carcinoma | Neoplasms, Colorectal

United States, France, United Kingdom
ValiRx Plc

Completed

Dose Finding Safety Study of VAL201 in Cancer Patients (VAL201-001)

Stage III Prostate Carcinoma | Stage IV Prostate Carcinoma
NuCana plc

Terminated

NUC-1031 in Patients With Platinum-Resistant Ovarian Cancer

Ovarian Cancer

United States, United Kingdom
Viatar LLC
Commonwealth Hematology-Oncology, P.C.

Completed

Collection of Blood Specimens for Circulating Tumor Cell Analysis

Breast Cancer | Colorectal Cancer | Prostate Cancer

United States
Derm Research, PLLC
WFH MEDICAL, LLC

Completed

Aczone 5% Gel as Maintenance Treatment of Acne Vulgaris Following Completion of Oral Doxycycline and Aczone 5% Gel

Acne Vulgaris

United States
Universal Diagnostics
Premier Research Group plc; Science 37; Yanuvia, LLC

Recruiting

A Prospective, Multi-center, Observational Study for Signal-C Test Evaluation

Colorectal Cancer | Advanced Adenocarcinoma

United States
Acacia Pharma Ltd
Premier Research Group plc; Amicus CD LLC

Recruiting

Study of Intravenous Amisulpride for Prophylaxis of Post-operative Nausea and Vomiting (PONV) in Pediatric Patients

Nausea and Vomiting, Postoperative

Canada, United States, Germany, France
Nova Therapeutics LLC
Chinese PLA General Hospital

Recruiting

CART-PSMA Cells for Advanced Prostate Cancer

Prostate Cancer

China
Pega-One S.A.S.
ICON plc

Withdrawn

Imgatuzumab in Patients With Advanced Cutaneous Squamous Cell Carcinoma (I-PACE)

Cutaneous Squamous Cell Carcinoma
MaxWell Clinic, PLC

Recruiting

Utilizing Novel Blood RNA Biomarkers as a Diagnostic Tool in the Identification of Long COVID-19

Long COVID

United States
Oculis
ICON plc

Recruiting

Study of the Efficacy and Safety of OCS-01 Eye Drops in Subjects With Diabetic Macular Edema (DIAMOND-2)

Diabetic Macular Edema

United States
Gedeon Richter Plc.

Recruiting

Study to Evaluate Efficacy, Safety, and Tolerability of RGH-706 in Prader-Willi Syndrome

Prader-Willi Syndrome

United States, Spain, Czechia, Italy, France
Adaptimmune
ICON plc

Recruiting

ADP-A2M4CD8 as Monotherapy or in Combination With Either Nivolumab or Pembrolizumab in HLA-A2+ Subjects With MAGE-A4 Positive Tumors (SURPASS)

Melanoma | Head and Neck Cancer | Esophageal Cancer | Ovarian Cancer | Endometrial Cancer | Urothelial Cancer | Gastric (Stomach) Cancer | Esophagogastric Junction (EGJ) | Non-small Cell Lung (NSCLC)

United States, Canada, Spain, Belgium

Clinical Trials Sponsored by Optos, PLC

Sponsors and Collaborators

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CROs in Suriname

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