Clinical Trials Sponsored by Optum, Inc.

Total 35440 results

UNC Lineberger Comprehensive Cancer Center
AstraZeneca; Rgenix, Inc.

Recruiting

Abequolixron (RGX-104) and Durvalumab in Lung Cancer

Non-Small Cell Lung Cancer

United States
UNC Lineberger Comprehensive Cancer Center
Millennium Pharmaceuticals, Inc.

Terminated

A Phase I Study of Alisertib + R-EPOCH for Treatment of Myc-Positive Aggressive B-cell Lymphomas

Follicular Lymphoma | Burkitt Lymphoma | Diffuse Large B-cell Lymphoma

United States
UNC Lineberger Comprehensive Cancer Center
G1 Therapeutics, Inc.

Recruiting

Study of Trilaciclib and Lurbinectidin

Lung Cancer | Small-cell Lung Cancer

United States
UNC Lineberger Comprehensive Cancer Center
Cerulean Pharma Inc.

Terminated

Neoadjuvant Chemoradiotherapy With CRLX-101 and Capecitabine for Rectal Cancer

Rectal Cancer

United States
Mylan Pharmaceuticals Inc
Momenta Pharmaceuticals, Inc.

Completed

Extension Study of MYL-1701P-3001 for Safety and Efficacy

Diabetic Macular Edema

India
Verrica Pharmaceuticals Inc.
BioClinica, Inc.; Paidion Research, Inc.; Instat Consulting, Inc.

Completed

A Placebo-Controlled Study Using VP-102 in the Treatment of External Genital Warts (CARE-1)

Skin Diseases | Sexually Transmitted Diseases, Viral | Sexually Transmitted Diseases | Skin Diseases, Infectious | Warts | Papillomavirus Infections | Skin Diseases, Viral | Condylomata Acuminata

United States
Genentech, Inc.
Flatiron Health, Inc.; Foundation Medicine, Inc.

Completed

Prospective Clinicogenomic Program (PCG)

Non-Small Cell Lung Cancer (NSCLC) | Small-Cell Lung Cancer (SCLC)

United States
Mylan Pharmaceuticals Inc
Momenta Pharmaceuticals, Inc.

Completed

Comparative Study to Evaluate the Efficacy and Safety of MYL-1701P and Eylea® in Subjects With Diabetic Macular Edema (DME) (DME)

Diabetic Macular Edema

Japan, United States, Czechia, Germany, Hungary, India, Latvia, Poland, Russian Federation
HeartBeam, Inc.
Meditrial USA Inc.

Not yet recruiting

AIMIGo 12L ECG Synthesis Software Pivotal Study for Arrythmia Detection (VALID-ECG)

Atrial Fibrillation | Arrhythmias, Cardiac | Bradycardia | Tachycardia | Atrial Flutter

United States
GB002, Inc.

Recruiting

Efficacy and Safety of Seralutinib in Adult Subjects With PAH (PROSERA)

Pulmonary Arterial Hypertension

United States, Spain, Israel, Korea, Republic of, Netherlands, France, Singapore, United Kingdom, Lithuania, Australia, Latvia, Argentina, Portugal, Greece, Czechia, Puerto Rico, Belgium, Italy, Poland, Romania, Serbia, Austria, Chile, Denma... and more
Combangio, Inc
Kala Pharmaceuticals, Inc.

Recruiting

Trial to Evaluate Safety and Efficacy of KPI-012 Ophthalmic Solution in Participants With PCED (CHASE)

Persistent Corneal Epithelial Defect

United States
Vivani Medical, Inc
Medpace, Inc.

Not yet recruiting

Assessment of Safety, Tolerability and Drug Levels of NPM-119 in Participants With Type 2 Diabetes (LIBERATE-1)

Type 2 Diabetes
Verastem, Inc.
Mirati Therapeutics Inc.

Recruiting

Study of Avutometinib (VS-6766) + Adagrasib in KRAS G12C NSCLC Patients (RAMP204)

Non Small Cell Lung Cancer | Metastatic Cancer | Advanced Cancer | Malignant Neoplasm of Lung | Malignant Neoplastic Disease | KRAS Activating Mutation

United States
Criterium, Inc.
Novartis; Seagen Inc.

Recruiting

Clinical Trial of Alpelisb and Tucatinib in Patients With PIK3CA-Mutant HER2+ Metastatic Breast Cancer.

HER2-positive Metastatic Breast Cancer

United States
HBI Solutions Inc.
mProbe Inc.

Not yet recruiting

Development and Validation of a Multi-target, Blood-based NAFLD Diagnosis Test

NAFLD | NASH - Nonalcoholic Steatohepatitis
Neovasc Inc.
Shockwave Medical, Inc.

Recruiting

Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II (COSIRA-II)

Refractory Angina

United States, Canada
Cofactor Genomics, Inc.
Curebase Inc.

Recruiting

A Multicenter Cancer Biospecimen Collection Study

Renal Cell Carcinoma | Cervical Cancer | Hepatocellular Carcinoma | Colorectal Cancer | Triple Negative Breast Cancer | Small-cell Lung Cancer | Esophageal Squamous Cell Carcinoma | Urothelial Carcinoma | Cancer of Head and Neck | Lung Cancer, Nonsmall Cell | Gastroesophageal Junction Adenocarcinoma

United States
AVM Biotechnology Inc
Medpace, Inc.

Not yet recruiting

Evaluating AVM0703 for Treatment of COVID-19 or Influenza-mediated ARDS (AVM0703)

Covid19 | Influenza, Human | ARDS
Mylan Pharmaceuticals Inc

Completed

Food Study of Ondansetron Orally Disintegrating Tablets 8 mg to Zofran ODT® Tablets 8 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Food Study of Midodrine HCl Tablets 5 mg and ProAmatine® Tablets 5 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Quinapril HCl and Hydrochlorothiazide Tablets 20 mg/25 mg to Accuretic™ Tablets 20 mg/25 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Pioglitazone HCl Tablets 45 mg and Actos® Tablets 45 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Amlodipine and Benazepril HCl Capsules 10 mg/20 mg to Lotrel® Capsules 10 mg/20 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Doxycycline Monohydrate Tablets 150 mg and Adoxa Tablets 150 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Cetirizine HCl Tablets 10 mg and Zyrtec® Tablets 10 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Finasteride Tablets 5 mg and Proscar Tablets 5 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Food Study of Rabeprazole Sodium Delayed-Release Tablets 20 mg to Aciphex® Tablets 20 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Anagrelide Hydrochloride Capsules 1 mg to Agrylin® Capsules 1 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Ondansetron Orally Disintegrating Tablets 8 mg to Zofran ODT® Tablets 8 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Fexofenadine Tablets 180 mg and Allegra® Tablets 180 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Benazepril HCl and Hydrochlorothiazide Tablets 20 mg/25 mg to Lotensin HCT® Tablets 20 mg/25 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Metoprolol Tartrate/Hydrochlorothiazide Tablets 100/50 mg and Lopressor HCT® Tablets 100/50 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Food Study of Sertraline Hydrochloride Tablets 100 mg and Zoloft® Tablets 100 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Loxapine Succinate Capsules 25 mg and Loxitane® Capsules 25 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Food Study of Olanzapine Tablets 5 mg and Zyprexa® Tablets 5 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Food Study of Glipizide and Metformin HCl Tablets 5 mg/500 mg to Metaglip® Tablets 5 mg/500 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Metformin Hydrochloride ER Tablets 500 mg and Glucophage® XR Tablets 500 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Food Study of Paroxetine Hydrochloride Controlled-Release Tablets 25 mg to Paxil CR™ Tablets 25 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Ciprofloxacin Extended-Release Tablets 1000 mg and Cipro® XR Tablets 1000 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Food Study Metformin Hydrochloride ER Tablets 750 mg and Glucophage XR 750 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Metolazone Tablets 5 mg and Zaroloxyn® Tablets 5 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Food Study of Fexofenadine Tablets 180 mg and Allegra® Tablets 180 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Fluoxetine Capsules 40 mg and Prozac Pulvules 40 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Food Study of Escitalopram Oxalate Tablets 20 mg to Lexapro® Tablets 20 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Food Study of Ciprofloxacin Extended-Release Tablets 1000 mg and Cipro® XR Tablets 1000 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Food Study of Metoprolol Tartrate/Hydrochlorothiazide Tablets 100/50 mg to Lopressor HCT® Tablets 100/50 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Rabeprazole Sodium Delayed-Release Tablets 20 mg to Aciphex® Delayed-Release Tablets 20 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Cilostazol Tablets 100 mg and Pletal® Tablets 100 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fed Study of Finasteride Tablets 5 mg and Proscar® Tablets 5 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fed Study of Olmesartan Medoxomil and Hydrochlorothiazide Tablets 40 mg/25 mg and Benicar HCT® Tablets 40 mg/25 mg

Healthy

United States

Clinical Trials Sponsored by Optum, Inc.

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