Clinical Trials Sponsored by Orphan Australia

Total 1644 results

Orfagen
FDA Office of Orphan Products Development

Completed

Systemic and Local Diffusion of Ethanol After Administration of Ethanol 96% Formulated in a Gel and Ethanol 98% Solution by the Percutaneous Route, in Patients With Congenital Venous Malformations:Pharmacokinetic, Pharmacodynamic and Clinical Study.

Congenital Venous Malformation

United States, France
Aneira Pharma, Inc.
DataPharm Australia, CMAX Clinical Research, Agilex Australia

Not yet recruiting

Phase I Study of Safety and Pharmacokinetics of Topical Solution in Subjects With Androgenetic Alopecia

Androgenetic Alopecia
Murdoch Childrens Research Institute
Brockhoff Foundation Australia; Shepherd Foundation Australia

Completed

Protecting Young Special Risk Females From Cervical Cancer Through Human Papilloma Virus (HPV) Vaccination (HPV)

Cervical Cancer

Australia
Australian and New Zealand Intensive Care Research...
Melbourne Health; The Alfred; Barwon Health; Wellington Hospital; Monash Health; Austin... and other collaborators

Completed

The Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock Trial (VITAMINS)

Sepsis | Shock, Septic | Critically Ill | Vasoplegic Syndrome

Australia, New Zealand, Brazil
Curon Biopharmaceutical (Australia) Co Pty Ltd
Novotech (Australia) Pty Limited

Not yet recruiting

A Study of CN202 in Adult Subjects With Locally Advanced or Metastatic Solid Tumors or Hematologic Malignancies

Metastatic Solid Tumor | Hematologic Malignancies | Locally Advanced Solid Tumor
Curon Biopharmaceutical (Australia) Co Pty Ltd
Novotech (Australia) Pty Limited

Terminated

A Study of CN1 in Combination With CN401 in Adult Patients With Relapsed/Refractory Lymphoid Malignancies

Relapsed Lymphoid Malignancies | Refractory Lymphoid Malignancies

Australia
Curon Biopharmaceutical (Australia) Co Pty Ltd
Novotech (Australia) Pty Limited

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of CN1

B Cell Lymphoma | Advanced Solid Tumor

Austria
University of Sydney
National Heart Foundation, Australia; Meat & Livestock Australia

Completed

Glycemic Load, Weight Loss and Cardiovascular Disease Risk

Obesity | Overweight

Australia
60P Australia Pty Ltd

Not yet recruiting

A Clinical Evaluation of the Safety and Efficacy of Randomized Placebo Versus the 8-aminoquinoline Tafenoquine for Early Symptom Resolution in Patients With Mild to Moderate COVID 19 Disease and Low Risk of Disease Progression

Infectious Disease | SARS-CoV-2 | Severe Acute Respiratory Syndrome Coronavirus 2 | COVID 19 Disease | Mild to Moderate COVID 19 Disease
Inipharm Australia Pty Ltd

Recruiting

A Study of INI-822 in Healthy Volunteers and Participants With Non-alcoholic Steatohepatitis (NASH) or Presumed NASH

Non-alcoholic Steatohepatitis

Australia
Oticara Australia PTY LTD

Terminated

Treatment of Eosinophilic Chronic Rhinosinusitis Utilizing Betamethasone Dipropionate Nasal Cream (OT-007)

Chronic Rhinosinusitis (Diagnosis)

Australia
StimAire Australia Pty Ltd

Terminated

StimAire Sleep Study

Obstructive Sleep Apnea

Australia
Cyclomedica Australia PTY Limited

Terminated

A Comparison of Technegas and Xenon-133 Planar Lung Imaging in Subjects Referred for Ventilation Scintigraphy

Lung Structure Determination

United States
St George Hospital, Australia

Completed

Measuring Blood Pressure in Pregnancy Using Mercury and Automated Device (PRAM)

Hypertension | Pregnancy | Pre Eclampsia

Australia
St George Hospital, Australia

Unknown

Boost Use in Breast Conservation Radiotherapy

Breast Neoplasms

Australia
Kangabio AUSTRALIA LTD PTY

Not yet recruiting

A Phase 1, First-in-Human of KGX101 to Patients With Advanced or Metastatic Solid Tumors

Advanced or Metastatic Solid Tumors

Australia
AJNA Australia Pty Ltd

Not yet recruiting

A SAD, MAD and Food Effect Study to Evaluate the Safety, Tolerability, PK, and PD of AJA001 in Healthy Subjects

Healthy Volunteers
Pharmanex
Clinical Research Australia

Recruiting

Nutritional Supplement's Effects on Cognition

Healthy | Cognition | Dietary Supplement

Australia
Oticara Australia PTY LTD

Recruiting

The Effect of Intra-sinus Application of Betamethasone Dipropionate Nasal Cream on Patients With Chronic Rhinosinusitis Post Functional Endoscopic Sinus Surgery (FESS)

Chronic Rhinosinusitis (Diagnosis)

Australia
Melanoma Institute Australia
Novartis

Recruiting

Molecular Profiling and Matched Targeted Therapy for Patients With Metastatic Melanoma (MatchMel)

Melanoma

Australia
St George Hospital, Australia

Recruiting

Hemiablative Focal Brachytherapy Pilot Study

Prostate Cancer

Australia
Premier Specialists, Australia
Steritas

Active, not recruiting

Investigating the Morbidity of Glucocorticoid Use in Patients With Autoimmune Bullous Diseases (AIBDs)

Glucocorticoids Toxicity | Autoimmune Bullous Dermatosis

Australia
Pieris Australia Pty Ltd

Completed

Study of Multiple Doses of PRS-060 Administered by Oral Inhalation in Subjects With Mild Asthma

Asthma

Australia
Cyclomedica Australia PTY Limited

Terminated

Compare Technegas Ventilation-Perfusion SPECT and Xenon Ventilation-Perfusion Planar Imaging for Pulmonary Embolism

Pulmonary Embolism

United States
St George Hospital, Australia

Completed

Clean Intermittant Self Catheterisation: A Trial Comparing Single Use vs Reuse of Nelaton Catheters (SURE)

Urinary Retention

Australia
St George Hospital, Australia

Completed

Does Patient Activity Level Affect 24-Hour Pad Test Results in Stress-Incontinent Women

24-hour Pad Test Weight Gain With and Without Activity
St George Hospital, Australia

Completed

Brain Metastases Study: Radiotherapy Fractionation Schemes in the Treatment of Brain Metastases

Neoplasm Metastasis | Brain Neoplasms

Australia
St George Hospital, Australia

Completed

Mouth Care Regimes During Radiotherapy

Head and Neck Neoplasms

Australia
Swedish Orphan Biovitrum
CMIC Co, Ltd. Japan

Recruiting

A Study of Anakinra in Japanese Patients With Still's Disease (SJIA and AOSD)

Still's Disease, Adult-Onset | Still's Disease, Juvenile Onset

Japan
Fred Hutchinson Cancer Center
Swedish Orphan Biovitrum

Recruiting

Anakinra for the Prevention of Cytokine Release Syndrome and Neurotoxicity in Patients With B-Cell Non-Hodgkin Lymphoma Receiving CD19-Targeted CAR-T Cell Therapy

B-Cell Non-Hodgkin Lymphoma

United States
Bioverativ Therapeutics Inc.
Swedish Orphan Biovitrum

Completed

Study to Evaluate the Safety, Pharmacokinetics and Efficacy of Recombinant Factor VIII Fc Fusion Protein (rFVIIIFc) in Previously Treated Subjects With Severe Hemophilia A

Severe Hemophilia A

United States, United Kingdom, Spain, Hong Kong, Israel, New Zealand, Sweden, Australia, Brazil, Japan, Austria, Belgium, Italy, India, Switzerland, Canada, France, Germany, South Africa
Arbeitsgemeinschaft medikamentoese Tumortherapie
AOP Orphan Pharmaceuticals AG

Completed

Addition of P1101 to Imatinib Treatment in Patients With Chronic Phase Chronic Myeloid Leukaemia Not Achieving a Complete Molecular Response

Chronic Phase Chronic Myeloid Leukemia

Austria
St George Hospital, Australia
The University of New South Wales; Australian Government Department of Health... and other collaborators

Unknown

Tai Chi or Hydrotherapy for People With Osteoarthritis of the Hip(s) or Knee(s)

Osteoarthritis, Knee | Osteoarthritis, Hip

Australia
Bioverativ Therapeutics Inc.
Swedish Orphan Biovitrum

Completed

Pharmacokinetics and Safety of rFVIIIFc Manufactured at 15,000 L (15K) Scale (Elevate)

Severe Hemophilia A

United States, Australia, New Zealand
Bioverativ Therapeutics Inc.
Swedish Orphan Biovitrum

Completed

Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Recombinant Coagulation Factor VIII Fc Fusion Protein (rFVIIIFc) in Previously Treated Pediatric Subjects With Hemophilia A (Kids ALONG)

Hemophilia A

United States, Poland, United Kingdom, Netherlands, South Africa, Hong Kong, Australia, Ireland
Bioverativ Therapeutics Inc.
Swedish Orphan Biovitrum

Completed

Study of Recombinant Coagulation Factor IX Fc Fusion Protein, BIIB029, in Previously Treated Pediatric Participants With Hemophilia B (Kids B-LONG)

Hemophilia B

United States, United Kingdom, South Africa, Netherlands, Ireland, Australia
Bioverativ Therapeutics Inc.
Swedish Orphan Biovitrum

Terminated

Fc factOrs and Real-World hemophiliA Patient-ReporteD Outcomes (FORWARD)

Hemophilia A | Hemophilia B

United States
Bioverativ Therapeutics Inc.
Swedish Orphan Biovitrum

Completed

Study of Recombinant Factor IX Fc Fusion Protein (rFIXFc) in Participants With Hemophilia B

Severe Hemophilia B

Sweden, United States, France, Italy, Russian Federation, United Kingdom, Germany, China, Poland, Japan, Australia, Brazil, Canada, India, South Africa, Hong Kong, Belgium
Brett King
Swedish Orphan Biovitrum

Terminated

Study to Evaluate the Use of Palifermin to Treat Toxic Epidermal Necrolysis

Stevens-Johnson Syndrome | Toxic Epidermal Necrolysis

United States
Mayo Clinic
University of Florida; Orphan Medical

Completed

Betaine in Patients With Nonalcoholic Steatohepatitis

Nonalcoholic Steatohepatitis

United States
Australian and New Zealand Intensive Care Research...
National Health and Medical Research Council, Australia; Monash University

Recruiting

Early Rehabilitation in Patients on Extracorporeal Membrane Oxygenation (ECMO-Rehab)

Extracorporeal Membrane Oxygenation Complication

Australia
Menzies School of Health Research
Northern Territory Government of Australia; Australian Government Department...

Active, not recruiting

Hearing for Learning Initiative - a Health Facilitator Model for Otitis Media (HfLI)

Otitis Media | Conductive Hearing Loss

Australia
VITATOPS
National Health and Medical Research Council, Australia; National Heart Foundation... and other collaborators

Completed

VITATOPS: A Study of VITAmins TO Prevent Stroke

Stroke | Transient Ischemic Attack

Hong Kong, United Kingdom, Netherlands, Singapore, Australia, New Zealand, Italy, India, Malaysia, Portugal, United States, Sri Lanka, Philippines, Austria, Belgium, Brazil, Georgia, Moldova, Republic of, Pakistan, Serbia
Australian National University

Recruiting

Nebulised Heparin in Patients With Severe COVID-19 (CHARTER-MT)

Covid19 | Respiratory Failure

United States
Australian & New Zealand Children's Haematology...
National Health and Medical Research Council, Australia; Secura Bio, Inc.

Terminated

A Study of Panobinostat in Pediatric Patients With Solid Tumors Including MRT/ATRT (NORTH)

Rhabdoid Tumor | Atypical Teratoid/Rhabdoid Tumor | Malignant Rhabdoid Tumor | Recurrent Brain Tumor, Childhood

Australia, New Zealand, United States
Australian National University

Completed

IN2SHAPE: A Study of Physical Activity and Depressive Symptoms in Adolescence (IN2SHAPE)

Depression

Australia
Bioverativ, a Sanofi company
Swedish Orphan Biovitrum

Completed

An Open Label Study to Determine the Safety and Efficacy of Replacement Factor VIII Protein (Known as rFVIIIFc) in Previously Untreated Males With Severe Hemophilia A

Hemophilia A

United States, France, Italy, Spain, Netherlands, United Kingdom, Ireland, New Zealand, Poland, Australia, Germany, Brazil, Sweden, Canada
Bioverativ, a Sanofi company
Swedish Orphan Biovitrum

Completed

A Study to Evaluate Efficacy of rFVIIIFc for Immune Tolerance Induction (ITI) in Severe Hemophilia A Participants With Inhibitors Undergoing the First ITI Treatment (verITI-8 Study)

Hemophilia A With Inhibitors

United States, Spain, Canada, Belgium, France, Bulgaria, Italy, United Kingdom, Japan, Germany
Swedish Orphan Biovitrum
Pediatric Rheumatology International Trials Organization

Completed

Kineret CAPS Post Authorisation Study

Cryopyrin-Associated Periodic Syndromes

United Kingdom, Netherlands
FDA Office of Orphan Products Development
Bezoloven, Inc.

Withdrawn

Penicillamine Chelation for Children With Lead Poisoning

Vitamin D Deficiency | Lead Poisoning

United States

Clinical Trials Sponsored by Orphan Australia

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Peru

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations