Clinical Trials Sponsored by Pharmaceutical Research Network

Total 2614 results

Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Assess Bioequivalence of a New Tapentadol Extended-Release 250-mg Tablet With Respect to a Tapentadol Extended-Release 250-mg Tablet in Healthy Participants

Healthy

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

An Efficacy Study of JNJ-39220675 and Pseudoephedrine in Participants With Allergic Rhinitis

Allergic Rhinitis

Canada
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Evaluate the Relative Bioavailability, Food Effect and Effect of Ketoconazole on the Rate and Extent of Absorption of Solid Dosage Formulation(s) of JNJ-40411813

Healthy

Belgium
Johnson & Johnson Pharmaceutical Research & Development...

Completed

Single and Multiple Dose Study to Explore the Safety and Pharmacokinetics of JNJ-39758979 In Healthy Male Volunteers of Either Caucasian or Japanese Descent

Healthy

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study To Investigate The Effect of JNJ-39758979 on Histamine Induced Itch in Healthy Male Volunteers

Histamine Induced Itch

United Kingdom
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Doses of JNJ-38431055, Sitagliptin, and Co-administration of JNJ-38431055 and Sitagliptin

Diabetes Mellitus, Type 2

United States
Johnson & Johnson Pharmaceutical Research & Development...

Withdrawn

A Study of Patients Treated With Erythropoietin Receptor Agonists for Anemia Who Developed Anti-erythropoietin Antibodies

Anemia
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-40411813 in Male and Female Elderly Patients

Healthy

Belgium
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Pharmacokinetic Study to Characterize JNJ-39393406 in the Cerebrospinal Fluid of Healthy Volunteers

Healthy Volunteers
Johnson & Johnson Pharmaceutical Research & Development...

Completed

An Efficacy, Safety, and Tolerability Study of Canagliflozin (JNJ-28431754) in Patients With Type 2 Diabetes

Diabetes Mellitus, Type II | Diabetes Mellitus, Non Insulin Dependent

United States, Poland, Bulgaria, India, Malaysia, Romania, Canada, Russian Federation, Argentina, Puerto Rico, Czech Republic, United Kingdom, Mexico
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of the Safety and Effectiveness of Canagliflozin (JNJ-28431754) in Promoting Weight Loss in Overweight and Obese Patients Who do Not Have Diabetes

Obesity

United States, Puerto Rico
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Investigate How JNJ-38518168 May Affect the Plasma Levels of Methotrexate in Rheumatoid Arthritis Participants

Rheumatoid Arthritis

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Assess the Bioequivalence of 2 Fixed Dose Combination (FDC) Tablets of Canagliflozin and Metformin Immediate Release (IR) (50 mg/1,000 mg) With Respect to the Individual Components of Canagliflozin (1 x 100 mg) and Metformin IR Tablets (2 x 1,000 mg) in Healthy Volunteers

Healthy

United States
Johnson & Johnson Pharmaceutical Research & Development...

Terminated

An Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics Study of JNJ-17299425 in Participants With Traumatic Brain Injury

Traumatic Brain Injury

France, Belgium
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of Risk Factors for Anti-erythropoietin Antibody Positive Pure Red Cell Aplasia Among Patients With Chronic Kidney Disease Receiving Epoetin Alfa

Pure Red-cell Aplasia

United Kingdom, Sweden, South Africa, Brazil, Norway, France, Thailand
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of Patients With Pure Red Cell Aplasia Associated With Recombinant Human Erythropoietin Treatment

Pure Red-cell Aplasia

United Kingdom, Sweden, South Africa, Brazil, Canada, Germany, Norway, Thailand
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Evaluate the Effect of JNJ-28431754 (Canagliflozin) on Post-Meal Glucose in Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of Two Methods for Determining the Renal Threshold for Glucose in Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

Germany
Johnson & Johnson Pharmaceutical Research & Development...

Completed

The Effect of an Adhesive Overlay on the Delivery of Contraceptive Hormones From ORTHO EVRA® in Healthy Women

Healthy Volunteers

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

Study of Letrozole Plus Tipifarnib or Placebo in the Treatment of Advanced Breast Cancer

Breast Cancer

United Kingdom, United States, France, Russian Federation, Belgium, Netherlands
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Evaluate the Hormone Exposure From Multiple Commercial Lots of ORTHO EVRA (a Transdermal Contraceptive Patch)

Female Contraception | Contraception
Johnson & Johnson Pharmaceutical Research & Development...

Completed

Mode of Action of Topiramate in the Treatment of Obese Patients With and Without Type 2 Diabetes Mellitus

Obesity | Diabetes Mellitus Type 2
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Assess the Effects of Canagliflozin (JNJ-28431754) on the Pharmacokinetics and Safety of an Oral Contraceptive in Healthy Volunteers

Healthy
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Bioequivalence Study of 2 Formulations of Rabeprazole Sodium and Evaluation of the Effect of Food on Rabeprazole Sodium in Healthy Adult Volunteers

Healthy
Johnson & Johnson Pharmaceutical Research & Development...

Completed

Risk of Shopping Behavior of Tapentadol Immediate-Release (IR) Compared to Oxycodone Immediate-Release (IR)

Substance Abuse Detection
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Pharmacodynamics, Pharmacokinetics, and Safety Study of Hydrochlorothiazide and Canagliflozin in Healthy Volunteers

Healthy
Johnson & Johnson Pharmaceutical Research & Development...

Terminated

A Study of the Histone-deacetylase Inhibitor JNJ-26481585 in Patients With Advanced or Refractory Leukemia or Myelodysplastic Syndrome

Myelodysplastic Syndromes | Advanced or Refractory Leukemia

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Pharmacokinetic Dose Proportionality Study of Canagliflozin in Healthy Volunteers

Healthy

Belgium
Johnson & Johnson Pharmaceutical Research & Development...

Withdrawn

Study of JNJ-39758979 in Symptomatic Adult Patients With Uncontrolled Asthma

Asthma
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Safety Study of Epoetin Alfa in Patients With Cancer Who Have Chemotherapy-Related Anemia

Neoplasms | Anemia
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Compare the Bioequivalence of 50-mg Tapentadol (CG5503) Dose Administered as Two 50-mg Tablets Relative to One 100-mg Tablet

Healthy Volunteer
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Assess the Effects of Multiple-Dose Probenecid on the Multiple-Dose Pharmacokinetics of Canagliflozin in Healthy Volunteers

Healthy

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Evaluate the Safety and Effectiveness of Topiramate Compared to Placebo in the Treatment of Patients With Bipolar I Disorder

Mental Disorders | Mood Disorders | Bipolar Disorder | Affective Disorders, Psychotic
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of Dopamine Type 2 (D2) Receptor Occupancy Following a Single Oral Dose of OROS Paliperidone

Schizophrenia
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Evaluate the Efficacy and Safety of Three Fixed Doses of Extended-release Paliperidone in Subjects With Bipolar I Disorder

Mood Disorders | Bipolar Disorder
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Comparison of the Pharmacokinetics and Safety of Long-acting Injectable Risperidone When Administered to Gluteal or Deltoid Intramuscular Injection Sites in Stable Schizophrenia Patients.

Schizophrenia
Johnson & Johnson Pharmaceutical Research & Development...

Terminated

A Study of the Efficacy and Safety of Topiramate in Obese, Type 2 Diabetic Patients Inadequately Controlled on Sulfonylurea Therapy

Obesity | Diabetes Mellitus, Type 2 | Diabetes Mellitus, Adult-Onset
Johnson & Johnson Pharmaceutical Research & Development...

Terminated

A Study on Efficacy and Safety of Topiramate in Treatment of Obese Subjects With Dyslipidemia

Obesity | Hypertriglyceridemia | Hyperlipidemia
Johnson & Johnson Pharmaceutical Research & Development...

Terminated

A Study on the Efficacy and Safety of Long-Term Treatment and Re-Treatment of Lower Extremity Diabetic Ulcers With REGRANEX

Diabetic Foot | Foot Ulcer | Skin Ulcer | Diabetic Neuropathies
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of the Effectiveness and Safety of Topiramate in the Treatment of Children With Epilepsy

Epilepsy | Seizures | Epilepsies, Partial
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Bioequivalence Study of 15 mg ER OROS Paliperidone

Schizophrenia
Johnson & Johnson Pharmaceutical Research & Development...

Completed

The Efficacy and Safety of Risperidone in the Treatment of Adolescents With Schizophrenia

Schizophrenia
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of QT and QTc Intervals in Patients Administered Immediate Release Paliperidone

Schizophrenia | Schizoaffective Disorder
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Evaluate the Exposure of Norelgestromin and Ethinyl Estradiol From Commercial Lots of EVRA (a Transdermal Contraceptive Patch Manufactured by LOHMANN Therapie-Systeme) and CILEST (an Oral Contraceptive)

Female Contraception | Contraception
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of the Efficacy and Safety of Topiramate Treatment in Patients With Epilepsy

Epilepsy | Seizures
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of Effectiveness and Safety of Paliperidone Extended-release (ER) Tablets in the Prevention of Recurrence in Adult Patients With Schizophrenia.

Schizophrenia
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A 52-week, Open-label Extension Study Following a 6-week, Double-blind, Placebo- and Active- Controlled Study (R076477-SCH-303) to Evaluate the Safety and Tolerability of Paliperidone ER in Subjects With Schizophrenia

Schizophrenia
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Phase 1 Bioavailability Study of Topiramate Oral Liquid Formulation Compared to the Marketed Sprinkle Capsule Formulation in Healthy Adults

Epilepsy
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of the Effectiness and Safety of Levofloxacin in Treating Children With a Rapid and Severe Onset of Infection and Inflammation of the Middle Ear That is Difficult to Treat

Otitis Media
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of Safety and Efficacy of Topiramate in Male Patients With Abdominal Obesity

Obesity

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