Clinical Trials Sponsored by Servier

Total 6447 results

Servier Affaires Médicales

Recruiting

An Early Access Study of Ivosidenib in Patients With a Pretreated Locally Advanced or Metastatic Cholangiocarcinoma (ProvIDHe)

Cholangiocarcinoma

France, Netherlands, Spain, Belgium, Sweden, Italy, Australia, Austria, Germany, United Kingdom
Servier
Servier Pharmaceuticals, LLC

Available

Vorasidenib Expanded Access Program

Pathologic Processes | Glioma | Neoplasms | Neoplasms by Histologic Type | Neoplasms, Glandular and Epithelial | Recurrence | Disease Attributes | Neoplasms, Germ Cell and Embryonal | Neoplasms, Neuroepithelial | Neuroectodermal Tumors | Neoplasms, Nerve Tissue
Servier Affaires Médicales

Active, not recruiting

Management of Metastatic Colorectal Cancer: A Clinical and Patient Perspective (PROMETCO)

Metastatic Colorectal Cancer

Netherlands, Belgium, Spain, France, Italy, Sweden, Slovenia, Germany, Argentina, Austria, Croatia, Czechia, Greece, Hungary, Ireland, Portugal, Switzerland, United Kingdom
Servier Affaires Médicales

Recruiting

Effectiveness of a Combination of Trimetazidine With One Hemodynamic Agent in Patients Recently Diagnosed With Stable Angina and Still Symptomatic Despite First Line Hemodynamic Therapy

Stable Angina

Romania
Servier Affaires Médicales

Recruiting

An Open-label Phase 3b Study of Ivosidenib in Combination With Azacitidine in Adult Patients Newly Diagnosed With IDH1m Acute Myeloid Leukemia (AML) Ineligible for Intensive Induction Chemotherapy.

Acute Myeloid Leukemia (AML)

Netherlands, Italy, Austria, France
Servier Affaires Médicales

Completed

aCute HemORrhoidal Disease evALuation International Study (CHORALIS)

Hemorrhoids

France
Servier Affaires Médicales

Completed

Evaluation of Type 2 Diabetes Treatment

Type2 Diabetes

Azerbaijan
Servier Affaires Médicales

Completed

Observational Study of Effectiveness and Tolerability of Gliclazide MR 60mg in Diabetic Patients Fasting During RAMADAN (DIA-RAMADAN)

Type 2 Diabetes

France
Servier Affaires Médicales

Active, not recruiting

RWE on Patients With mPDAC Long-term Survival After Treatment With Liposomal Irinotecan (NALLONG)

Pancreatic Cancer Metastatic

Germany
Servier Affaires Médicales

Completed

Chronic VEnous dIsorders maNagement and Treatment effectivenesS evaluaTion in Chronic vEnous Disease, an International Program (VEIN STEP)

Chronic Venous Disease

France
Servier

Completed

Non-drug Treatment Study in Parkinson's Disease Patients and Healthy Volunteers to Collect Biological Samples in Order to Assess ex Vivo the Activity of Candidate Therapies and Develop Novel Analytical Methods for Biomarkers (IRIS-CLE-LRRK2)

Parkinson Disease

France
Servier

Completed

Evaluation of the Clinical Efficacy and Safety of Amlodipine 5mg/ Bisoprolol Fumarate 5mg /Perindopril Arginine 5mg Fixed-dose Combination in Capsule and Free Monotherapy at the Same Dose in Patients With Uncontrolled Essential Hypertension.

Essential Hypertension

Russian Federation
Servier

Active, not recruiting

A Phase 2 Study of Ivosidenib in Previously Treated Japanese Subjects With Nonresectable or Metastatic Cholangiocarcinoma With an IDH1 Mutation

Cholangiocarcinoma Non-resectable | Cholangiocarcinoma Metastatic

Japan
Servier Bio-Innovation LLC
Institut de Recherches Internationales Servier

Not yet recruiting

S095035 in Adult Participants With Advanced or Metastatic Solid Tumors With Deletion of the Methylthioadenosine Phosphorylase (MTAP) Gene

MTAP-deleted Solid Tumors
Institut de Recherches Internationales Servier

Not yet recruiting

Phase 2 Study of Irinotecan Liposome Injection, Oxaliplatin, 5-fluorouracil/Levoleucovorin in Japanese Participants Not Previously Treated for Metastatic Adenocarcinoma of the Pancreas

Metastatic Adenocarcinoma of the Pancreas

Japan
Institut de Recherches Internationales Servier

Active, not recruiting

Study of Orally Administered AG-881 in Patients With Advanced Solid Tumors, Including Gliomas, With an IDH1 and/or IDH2 Mutation

Glioma

United States
Institut de Recherches Internationales Servier

Active, not recruiting

Study of AG-120 and AG-881 in Subjects With Low Grade Glioma

Glioma

United States
Servier
Institut de Recherches Internationales Servier

Terminated

An Experimental Medicine Clinical Study to Compare Peripheral Immune System From Subjects Without Cancer Diagnosis and Patients With Solid Tumours. (IMMUNOPBMC)

Immune System

France
Institut de Recherches Internationales Servier

Active, not recruiting

Study of Vorasidenib (AG-881) in Participants With Residual or Recurrent Grade 2 Glioma With an IDH1 or IDH2 Mutation (INDIGO)

Recurrent Glioma | Grade 2 Glioma | Residual Glioma

United States, Canada, Spain, Italy, United Kingdom, Switzerland, Israel, Japan, Netherlands, Germany, France
Institut de Recherches Internationales Servier

Completed

Study of AG-120 in Previously Treated Advanced Cholangiocarcinoma With IDH1 Mutations (ClarIDHy) (ClarIDHy)

Metastatic Cholangiocarcinoma | Advanced Cholangiocarcinoma

United States, Spain, Korea, Republic of, Italy, France, United Kingdom
Servier Deutschland GmbH
iOMEDICO AG

Completed

Trifluridin/tipirACil in meTastatIc Colorectal Cancer (TACTIC)

Metastatic Colorectal Cancer

Germany
Institut de Recherches Internationales Servier

Withdrawn

Clinical Investigation to Determine the Accuracy and Benefit of Cardioskin™ in Patients With Known Atrial Fibrillation

Atrial Fibrillation

Netherlands
Institut de Recherches Internationales Servier

Completed

Study of Oral Lucitanib (E-3810), a Dual VEGFR-FGFR Tyrosine Kinase Inhibitor, in Patients With Solid Tumors

Solid Tumors

Italy, France, Spain
Institut de Recherches Internationales Servier

Completed

Efficacy of Agomelatine in Patients With Obsessive-Compulsive Disorder

Obsessive Compulsive Disorder

Israel
Institut de Recherches Internationales Servier

Completed

Efficacy and Safety of 3 Doses of S47445 Versus Placebo in Patients With Alzheimer's Disease at Mild to Moderate Stages With Depressive Symptoms

Alzheimer's Disease

Brazil, South Africa, Chile, Hungary, Bulgaria, Czechia, Germany, Japan, Mexico, Poland, Russian Federation, Slovakia
Institut de Recherches Internationales Servier

Completed

Efficacy and Safety of Ivabradine on Top of Atenolol in Stable Angina Pectoris (ASSOCIATE)

Angina Pectoris

Canada
UNICANCER
Servier

Not yet recruiting

Safety of Trifluridine/Tipiracil in Patients With Dihydropyrimidine Dehydrogenase Deficiency Diagnosed With Metastatic Colorectal or Gastroesophageal Cancer (TRIFLUOX-DP)

Metastatic Colorectal Cancer | Metastatic Gastroesophageal Adenocarcinoma | DPD Deficiency
Servier Russia

Completed

Description of the Effectiveness, Safety, Tolerability and Adherence to Amlodipine/Atorvastatin/Perindopril Single Pill Combination Treatment in Patients With Arterial Hypertension and Dyslipidemia (TARGET) (TARGET)

Arterial Hypertension | HTN

Russian Federation
Servier Russia

Completed

Efficacy and Tolerability of Venoactive Drugs in Patients With Chronic Venous Diseases C4a&b in Real Clinical Practice. (VAP-PRO-C4)

Chronic Venous Diseases

Russian Federation
Servier Russia

Completed

VAP-PRO-C6. Effectiveness and Tolerability of Venoactive Drugs in Combination Therapy in Patients With CVD (CEAP C6) (VAP-PRO-C6)

Chronic Venous Insufficiency

Russian Federation
Servier Russia

Completed

PRIDE. Assessment of the Efficacy, Adherence and Tolerability of the Single Pill Combination Bisoprolol/Perindopril (PRIDE)

Myocardial Infarction | Coronary Artery Disease | Arterial Hypertension

Russian Federation
Servier Russia

Completed

The Use of TrIple Fixed-dose Combination in the Treatment of Arterial Hypertension (TRICOLOR)

Arterial Hypertension

Russian Federation
Servier Russia

Completed

Data on the Impact of Different Treatment on the Quality of Life of Patients With Acute and Chronic Hemorrhoid Disease (EQUALISER)

Hemorrhoids

Russian Federation
Servier Russia

Completed

Assessment of the Efficacy and Tolerability of the Fixed-dose Combination of Bisoprolol/Perindopril (STYLE)

Arterial Hypertension | CHD - Coronary Heart Disease

Russian Federation
Servier Bio-Innovation LLC
Institut de Recherches Internationales Servier

Recruiting

A Phase 1, Open-Label Study to Evaluate the Effect of a Low-Fat Meal and Multiple Doses of Ciprofloxacin on the Pharmacokinetics of Vorasidenib in Healthy Subjects

Healthy Subjects

United States
Servier Bio-Innovation LLC
Institut de Recherches Internationales Servier

Recruiting

Ivosidenib, Nivolumab, and Ipilimumab Combination in Previously Treated Subjects With Nonresectable or Metastatic IDH1 Mutant Cholangiocarcinoma

IDH1-mutant Cholangiocarcinoma

United States, United Kingdom
Servier Bio-Innovation LLC
Institut de Recherches Internationales Servier

Recruiting

A Study of PRS-344/S095012 (PD-L1x4-1BB Bispecific Antibody-Anticalin Fusion) in Patients With Solid Tumors

Solid Tumor

Spain, Australia, Belgium, United States
Institut de Recherches Internationales Servier

Completed

Efficacy and Safety of Perindopril 5 mg / Indapamide 1.25 mg / Amlodipine 5 mg Fixed Combination in Hypertension

Hypertension

China
Institut de Recherches Internationales Servier

Completed

Effects of Ivabradine in Patients With Stable Coronary Artery Disease Without Clinical Heart Failure (SIGNIFY)

Coronary Artery Disease

United Kingdom, Italy
Institut de Recherches Internationales Servier

Terminated

Long-term Safety of Gevokizumab in the Treatment of Patients With Chronic Non-infectious Uveitis (EYEGUARD-X) (EYEGUARD-X)

Chronic Uveitis

Italy, United Kingdom, Korea, Republic of, Portugal, Taiwan, Australia, Turkey, Tunisia, Austria, France, Germany, Greece, Spain
Institut de Recherches Internationales Servier

Completed

S90652 in Paediatric Hypertension

Hypertension

France
Institut de Recherches Internationales Servier

Terminated

Efficacy and Safety of S18986 in the Treatment of Mild Cognitive Impairment Patients

Mild Cognitive Impairment

France
Institut de Recherches Internationales Servier

Completed

Efficacy and Safety of Ivabradine in Severe Congestive Heart Failure

Heart Failure, Congestive

Italy
Institut de Recherches Internationales Servier

Recruiting

Study of Orally Administered AG-120 in Subjects With Advanced Hematologic Malignancies With an IDH1 Mutation

Myelodysplastic Syndromes | Relapsed or Refractory Acute Myeloid Leukemia (AML) | Untreated AML | Other IDH1-mutated Positive Hematologic Malignancies

United States, France
Institut de Recherches Internationales Servier

Terminated

Study of AG-270 in Participants With Advanced Solid Tumors or Lymphoma With MTAP Loss

Lymphoma | Advanced Solid Tumors

United States, Spain, France
Institut de Recherches Internationales Servier

Active, not recruiting

Study of AG-120 (Ivosidenib) vs. Placebo in Combination With Azacitidine in Participants With Previously Untreated Acute Myeloid Leukemia With an IDH1 Mutation (AGILE)

Leukemia, Myeloid, Acute | Untreated AML | Newly Diagnosed Acute Myeloid Leukemia (AML) | AML Arising From Myelodysplastic Syndrome (MDS)

Spain, United States, France, Korea, Republic of, Taiwan, Australia, Canada, Germany, China, Italy, Austria, Czechia, Poland, Japan, United Kingdom, Russian Federation, Netherlands, Brazil, Israel, Mexico
Institut de Recherches Internationales Servier

Completed

Study of Orally Administered AG-120 in Subjects With Advanced Solid Tumors, Including Glioma, With an IDH1 Mutation

Glioma | Cholangiocarcinoma | Chondrosarcoma | Other Advanced Solid Tumors

United States, France
Institut de Recherches Internationales Servier

Completed

A Study of Vorasidenib in Participants With Moderate or Mild Hepatic Impairment and Matched Participants With Normal Hepatic Function

Hepatic Impairment

United States
Institut de Recherches Internationales Servier

Terminated

Efficacy of Gevokizumab in the Treatment of Patients With Behçet's Disease Uveitis (EYEGUARD™-B) (EYEGUARD™-B)

Behcet's Uveitis

Korea, Republic of, United Kingdom
Institut de Recherches Internationales Servier

Completed

Effects of Ivabradine on Cardiovascular Events in Patients With Moderate to Severe Chronic Heart Failure and Left Ventricular Systolic Dysfunction. A Three-year International Multicentre Study (SHIFT)

Chronic Heart Failure

France, Sweden

Clinical Trials Sponsored by Servier

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